nhr-182 (Caenorhabditis elegans)
Nuclear receptor

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00105 (zf-C4) IPR001628 WBGene00018265 T306343_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in regulation of transcription, DNA-templated. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human PPARD (peroxisome proliferator activated receptor delta). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
nhr-182
M00701_2.00		 Caenorhabditis elegans
DWBYGTGWCH
DGWCACRVWH		 PBM
Narasimhan et al.(2015)
pTH10779		 (Direct) (Direct)
nhr-182
M00702_2.00		 Caenorhabditis elegans
NNNHRTRNHN
NDNYAYDNNN		 PBM
Narasimhan et al.(2015)
pTH6106		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
CBG01250
M02391_2.00 		Caenorhabditis briggsae
WBYGTGTC
GACACRVW		 PBM
Weirauch et al.(2014)
pTH6110 		0.851 0.571
nhr-232
M00700_2.00 		Caenorhabditis elegans
NNTNTDWYN
NRWHANANN		 PBM
Narasimhan et al.(2015)
pTH10647 		0.812 0.514
For this family, TFs with SR scores > 0.745 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M00701_2.00 Nuclear receptor 4 76
M00702_2.00 Nuclear receptor 1 73

DNA Binding Domains

Protein ID Domain From To Sequence
F41B5.9 Nuclear receptor 4 76

Links

Other Nuclear receptor family TFs
Other Caenorhabditis elegans TFs

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55 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action