nhr-270 (Caenorhabditis elegans)
Nuclear receptor

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00105 (zf-C4) IPR001628 WBGene00020062 T306363_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in regulation of transcription, DNA-templated. Predicted to be located in nucleus. Is expressed in seam cell. Human ortholog(s) of this gene implicated in Alzheimer's disease; coronary artery disease; hepatocellular carcinoma; lipid metabolism disorder; and myocardial infarction. Orthologous to human PPARA (peroxisome proliferator activated receptor alpha). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No TFs with similar DNA binding domains

DNA Binding Domains

Protein ID Domain From To Sequence
R13D11.8 Nuclear receptor 68 137

Links

Other Nuclear receptor family TFs
Other Caenorhabditis elegans TFs

5 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
CBN07563 Caenorhabditis brenneri CBN07563 N 0.859
CRE18677 Caenorhabditis remanei CRE18677 N 0.833
CBN13714 Caenorhabditis brenneri CBN13714 N 0.768
CBG11459 Caenorhabditis briggsae CBG11459 N 0.750
CRE05426 Caenorhabditis remanei CRE05426 N 0.750