nhr-274 (Caenorhabditis elegans)
Nuclear receptor

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00105 (zf-C4) IPR001628 WBGene00021522 T306379_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in regulation of transcription, DNA-templated. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human PPARD (peroxisome proliferator activated receptor delta). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No TFs with similar DNA binding domains

DNA Binding Domains

Protein ID Domain From To Sequence
Y41D4B.21a Nuclear receptor 34 103
Y41D4B.21c Nuclear receptor 34 103

Links

Other Nuclear receptor family TFs
Other Caenorhabditis elegans TFs

23 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
CRE13698 Caenorhabditis remanei CRE13698 N 0.991
CJA01109 Caenorhabditis japonica CJA01109 N 0.991
CBN12278 Caenorhabditis brenneri CBN12278 N 0.990
CBG13579 Caenorhabditis briggsae CBG13579 N 0.990
Hba_13467 Heterorhabditis bacteriophora Hba_13467 N 0.974
CJA17398 Caenorhabditis japonica CJA17398 N 0.962
scaffold665-EXSNAP2012.4 Pristionchus exspectatus scaffold665-EXSNAP2012.4 N 0.924
CRE09284 Caenorhabditis remanei CRE09284 N 0.921
CBG10365 Caenorhabditis briggsae CBG10365 N 0.921
nhr-181 Caenorhabditis elegans WBGene00018189 N 0.921
CBG06579 Caenorhabditis briggsae CBG06579 N 0.905
nhr-260 Caenorhabditis elegans WBGene00016517 N 0.904
CRE09282 Caenorhabditis remanei CRE09282 N 0.903
CBN05437 Caenorhabditis brenneri CBN05437 N 0.898
nhr-262 Caenorhabditis elegans WBGene00008619 N 0.873
CRE02503 Caenorhabditis remanei CRE02503 N 0.854
CRE09477 Caenorhabditis remanei CRE09477 N 0.854
CBN09493 Caenorhabditis brenneri CBN09493 N 0.836
CJA43179 Caenorhabditis japonica CJA43179 N 0.834
CBN13714 Caenorhabditis brenneri CBN13714 N 0.819
CRE28929 Caenorhabditis remanei CRE28929 N 0.801
CRE05426 Caenorhabditis remanei CRE05426 N 0.795