nr1i2.L (Xenopus laevis)
Nuclear receptor

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source
PF00105 (zf-C4) IPR001628 XB-GENE-17336519 T307243_2.00 Misc (2018-Jan-19)

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
NR1I2
M03925_2.00
Homo sapiens
RGKKCRNNVRGKKCR

YGMMCYBNNYGMMCY
SELEX
Nitta et al.(2015)
NR1I2_1
0.960 0.714
NR1I2
M05625_2.00
Homo sapiens
VRGTTCRNNSRGKTCRH

DYGAMCYSNNYGAACYB
SELEX
Yin et al.(2017)
NR1I2_eDBD_HT-SELEX
0.960 0.729
NR1I2
M09283_2.00
Homo sapiens
DDRRBTYMDNNRAGKTCAN

NTGAMCTYNNHKRAVYYHH
Misc
Kulakovskiy et al.(2013)
NR1I2_HUMAN.H11MO.0.C
0.960 0.729
NR1I2
M05626_2.00
Homo sapiens
VRGKKCRNNVRGKKCRN

NYGMMCYBNNYGMMCYB
SELEX
Yin et al.(2017)
NR1I2_eDBD_Methyl-HT-SELEX
0.960 0.714
VDR
M03363_2.00
Homo sapiens
GRGTTCAYHGRGTTCA

TGAACYCDRTGAACYC
SELEX
Jolma et al.(2013)
VDR_1
0.958 0.714
Vdr
M03429_2.00
Mus musculus
RRGTTCAYHGRGTTCA

TGAACYCDRTGAACYY
SELEX
Jolma et al.(2013)
Vdr_1
0.958 0.714
VDR
M05877_2.00
Homo sapiens
HRRGTTCA

TGAACYYD
SMiLE-seq
Isakova et al.(2017)
VDR
0.958 0.714
VDR
M09269_2.00
Homo sapiens
NRGGKCANNGRGKKCR

YGMMCYCNNTGMCCYN
Misc
Kulakovskiy et al.(2013)
VDR_HUMAN.H11MO.0.A
0.958 0.714
Vdr
M09315_2.00
Mus musculus
NRGGKCANNGRGKKCR

YGMMCYCNNTGMCCYN
Misc
Kulakovskiy et al.(2013)
VDR_MOUSE.H11MO.0.A
0.958 0.714
VDR
M09606_2.00
Homo sapiens
NRRGGTCANNRRGKKCANNN

NNNTGMMCYYNNTGACCYYN
Misc
Heinz et al.(2010)
GM10855-VDR+vitD_GSE22484
0.958 0.729
VDR
M11116_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$VDR_Q3
0.958 0.729
VDR
M11117_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$VDR_Q6_01
0.958 0.714
VDR
M11118_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$VDR_Q6
0.958 0.714
ENSPMAG00000000180
M02403_2.00
Petromyzon marinus
RGKWCRN

NYGWMCY
PBM
Weirauch et al.(2014)
pTH5509
0.945 0.714
Nr1i2
M09316_2.00
Mus musculus
DDRRBTYMDNNRAGKTCAN

NTGAMCTYNNHKRAVYYHH
Misc
Kulakovskiy et al.(2013)
NR1I2_MOUSE.H11MO.0.C
0.918 0.700
ENSGALG00000028624
M02398_2.00
Gallus gallus
GRGKTCAH

DTGAMCYC
PBM
Weirauch et al.(2014)
pTH6492
0.906 0.657
Nr1i3
M09302_2.00
Mus musculus
DRGGTCANNNRAGTTYAN

NTRAACTYNNNTGACCYH
Misc
Kulakovskiy et al.(2013)
NR1I3_MOUSE.H11MO.0.C
0.873 0.629
NR1I3
M03924_2.00
Homo sapiens
RGKDYRNNNNRGKKYR

YRMMCYNNNNYRHMCY
SELEX
Nitta et al.(2015)
NR1I3_1
0.855 0.643
NR1I3
M05619_2.00
Homo sapiens
WDAGTTCAH

DTGAACTHW
SELEX
Yin et al.(2017)
NR1I3_FL_HT-SELEX
0.855 0.643
NR1I3
M09281_2.00
Homo sapiens
DRGGTCANNNRAGTTYAN

NTRAACTYNNNTGACCYH
Misc
Kulakovskiy et al.(2013)
NR1I3_HUMAN.H11MO.0.C
0.855 0.643
NR1I3
M05620_2.00
Homo sapiens
WDAGTTCRN

NYGAACTHW
SELEX
Yin et al.(2017)
NR1I3_FL_Methyl-HT-SELEX
0.855 0.657
EcR
M06414_2.00
Drosophila melanogaster
RAGGTCAW

WTGACCTY
B1H
Zhu et al.(2011)
EcR_SANGER_5_FBgn0000546
0.773 0.571
For this family, TFs with SR scores > 0.745 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
AAH41187 Nuclear receptor 35 104
CAA53006 Nuclear receptor 35 104

Links

Other Nuclear receptor family TFs
Other Xenopus laevis TFs

217 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
Nr1i3 Mus musculus ENSMUSG00000005677 D 0.873
Nr1i2 Mus musculus ENSMUSG00000022809 D 0.918
Vdr Mus musculus ENSMUSG00000022479 D 0.958
EcR Drosophila melanogaster FBgn0000546 D 0.773
NR1I3 Homo sapiens ENSG00000143257 D 0.855
VDR Homo sapiens ENSG00000111424 D 0.958
NR1I2 Homo sapiens ENSG00000144852 D 0.960
ENSGALG00000028624 Gallus gallus ENSGALG00000028624 D 0.906
ENSPMAG00000000180 Petromyzon marinus ENSPMAG00000000180 D 0.945
EcR Drosophila pseudoobscura FBgn0243551 I 0.773
ENSXMAG00000018707 Xiphophorus maculatus ENSXMAG00000018707 I 0.945
HMEL012265 Heliconius melpomene HMEL012265 I 0.775
ENSXMAG00000004608 Xiphophorus maculatus ENSXMAG00000004608 I 0.945
ENSXMAG00000003990 Xiphophorus maculatus ENSXMAG00000003990 I 0.822
VDR Tursiops truncatus ENSTTRG00000012578 I 0.958
ENSTSYG00000010757 Tarsius syrichta ENSTSYG00000010757 I 0.960
ENSTSYG00000003990 Tarsius syrichta ENSTSYG00000003990 I 0.931
vdra Takifugu rubripes ENSTRUG00000011907 I 0.945
GF13818 Drosophila ananassae FBgn0090845 I 0.773
GG10830 Drosophila erecta FBgn0103135 I 0.779
GL16258 Drosophila persimilis FBgn0153862 I 0.773
GA24101 Drosophila pseudoobscura FBgn0245500 I 0.773
GE19426 Drosophila yakuba FBgn0236769 I 0.773
GK21996 Drosophila willistoni FBgn0223981 I 0.773
GJ20887 Drosophila virilis FBgn0208023 I 0.782
GD10334 Drosophila simulans FBgn0182106 I 0.773
GM16480 Drosophila sechellia FBgn0171395 I 0.773
GB48059 Apis mellifera GB48059 I 0.772
GI21285 Drosophila mojavensis FBgn0144015 I 0.782
GH20948 Drosophila grimshawi FBgn0128410 I 0.782
ISCW003147 Ixodes scapularis ISCW003147 I 0.772
VDR Taeniopygia guttata ENSTGUG00000017093 I 0.959
NR1I3 Sorex araneus ENSSARG00000002684 I 0.898
Vdr Rattus norvegicus ENSRNOG00000054420 I 0.958
Nr1i3 Rattus norvegicus ENSRNOG00000003260 I 0.873
Nr1i2 Rattus norvegicus ENSRNOG00000002906 I 0.918
VDR Pteropus vampyrus ENSPVAG00000011085 I 0.958
NR1I3 Pteropus vampyrus ENSPVAG00000005540 I 0.873
NR1I2 Pteropus vampyrus ENSPVAG00000000884 I 0.955
NR1I2 Pan troglodytes ENSPTRG00000015263 I 0.960
NR1I3 Pan troglodytes ENSPTRG00000001582 I 0.855
ENSPSIG00000018108 Pelodiscus sinensis ENSPSIG00000018108 I 0.945
ENSPSIG00000004437 Pelodiscus sinensis ENSPSIG00000004437 I 0.930
ENSSHAG00000004437 Sarcophilus harrisii ENSSHAG00000004437 I 0.957
ENSSHAG00000016687 Sarcophilus harrisii ENSSHAG00000016687 I 0.926
NR1I3 Sus scrofa ENSSSCG00000006353 I 0.896
vdrb Takifugu rubripes ENSTRUG00000011576 I 0.945
nr1i2 Takifugu rubripes ENSTRUG00000003245 I 0.827
nr1i2 Tetraodon nigroviridis ENSTNIG00000013932 I 0.900
vdrb Tetraodon nigroviridis ENSTNIG00000007031 I 0.945
vdra Tetraodon nigroviridis ENSTNIG00000005559 I 0.919
VDR Tupaia belangeri ENSTBEG00000005717 I 0.958
ENSSTOG00000026741 Ictidomys tridecemlineatus ENSSTOG00000026741 I 0.958
ENSSTOG00000014988 Ictidomys tridecemlineatus ENSSTOG00000014988 I 0.918
ENSSTOG00000003818 Ictidomys tridecemlineatus ENSSTOG00000003818 I 0.935
VDR Sus scrofa ENSSSCG00000020864 I 0.958
NR1I2 Sus scrofa ENSSSCG00000011890 I 0.952
ENSPPYG00000004448 Pongo abelii ENSPPYG00000004448 I 0.958
PPAI003337 Phlebotomus papatasi PPAI003337 I 0.774
nr1i2.S Xenopus laevis XB-GENE-865343 I 0.989
vdr.S Xenopus laevis XB-GENE-864847 I 0.933
vdr Xenopus tropicalis XB-GENE-486505 I 0.931
nr1i3 Xenopus tropicalis XB-GENE-479859 I 0.814
SNAPOd2T00001873001 Oikopleura dioica SNAPOd2T00001873001 I 0.798
SMU15000518 Schmidtea mediterranea SMU15000518 I 0.747
LDEC009466 Leptinotarsa decemlineata LDEC009466 I 0.751
LCUP007589 Lucilia cuprina LCUP007589 I 0.775
CLEC002129 Cimex lectularius CLEC002129 I 0.757
Pvit_09406 Pogona vitticeps Pvit_09406 I 0.890
AALB010791 Anopheles albimanus AALB010791 I 0.775
AARA003299 Anopheles arabiensis AARA003299 I 0.775
AATE015478 Anopheles atroparvus AATE015478 I 0.775
MDOA013387 Musca domestica MDOA013387 I 0.775
ASTEI02489 Anopheles stephensi ASTEI02489 I 0.775
AQUA002870 Anopheles quadriannulatus AQUA002870 I 0.775
AMIN006955 Anopheles minimus AMIN006955 I 0.775
AMEM018998 Anopheles merus AMEM018998 I 0.775
AFUN015736 Anopheles funestus AFUN015736 I 0.775
AFAF021556 Anopheles farauti AFAF021556 I 0.775
AEPI000843 Anopheles epiroticus AEPI000843 I 0.775
ADIR001886 Anopheles dirus ADIR001886 I 0.775
ACUA000806 Anopheles culicifacies ACUA000806 I 0.775
ACOM026429 Anopheles coluzzii ACOM026429 I 0.775
Pvit_09404 Pogona vitticeps Pvit_09404 I 0.890
Pvit_07440 Pogona vitticeps Pvit_07440 I 0.945
Afo_R013462 Aptenodytes forsteri Afo_R013462 I 0.960
Aan_R009572 Calypte anna Aan_R009572 I 0.959
tetur01g15140 Tetranychus urticae tetur01g15140 I 0.772
tetur01g10970 Tetranychus urticae tetur01g10970 I 0.761
TC012112 Tribolium castaneum TC012112 I 0.772
SMAR011767 Strigamia maritima SMAR011767 I 0.772
RPRC014174 Rhodnius prolixus RPRC014174 I 0.772
Q9DFH3_CHICK Gallus gallus Q9DFH3_CHICK I 0.906
PHUM467460 Pediculus humanus PHUM467460 I 0.762
NV11088 Nasonia vitripennis NV11088 I 0.772
L798_01568 Zootermopsis nevadensis L798_01568 I 0.772
Alligator_sinensis_CCG005392.1 Alligator sinensis Alligator_sinensis_CCG005392.1 I 0.852
Alligator_sinensis_CCG006068.1 Alligator sinensis Alligator_sinensis_CCG006068.1 I 0.898
Cmyd_10001928 Chelonia mydas Cmyd_10001928 I 0.930
Ogr03312 Ophisaurus gracilis Ogr03312 I 0.904
Myotis_brandtii_VDR_10022134 Myotis brandtii Myotis_brandtii_VDR_10022134 I 0.958
Myotis_brandtii_NR1I2_10031787 Myotis brandtii Myotis_brandtii_NR1I2_10031787 I 0.964
Gfo_R005027 Geospiza fortis Gfo_R005027 I 0.959
ENSP00000356959 Macaca fascicularis ENSP00000356959 I 0.846
ENSP00000356959-D1 Bos grunniens ENSP00000356959-D1 I 0.896
ENSP00000336528 Macaca fascicularis ENSP00000336528 I 0.960
ENSP00000336528-D1 Bos grunniens ENSP00000336528-D1 I 0.952
ENSP00000229022-D1 Bos grunniens ENSP00000229022-D1 I 0.958
ENSMMUP00000008847 Macaca fascicularis ENSMMUP00000008847 I 0.958
Cmyd_10006875 Chelonia mydas Cmyd_10006875 I 0.945
KGM_08219 Danaus plexippus KGM_08219 I 0.775
ENSPMAG00000008742 Petromyzon marinus ENSPMAG00000008742 I 0.746
ENSGALG00000026166 Gallus gallus ENSGALG00000026166 I 0.959
NR1I3 Dasypus novemcinctus ENSDNOG00000045179 I 0.885
VDR Dasypus novemcinctus ENSDNOG00000039161 I 0.958
vdrb Danio rerio ENSDARG00000070721 I 0.945
nr1i2 Danio rerio ENSDARG00000029766 I 0.950
ENSCSAVG00000008466 Ciona savignyi ENSCSAVG00000008466 I 0.889
ENSCSAVG00000001918 Ciona savignyi ENSCSAVG00000001918 I 0.932
ENSCSAG00000006576 Chlorocebus sabaeus ENSCSAG00000006576 I 0.958
ENSCSAG00000002676 Chlorocebus sabaeus ENSCSAG00000002676 I 0.846
NR1I2 Cavia porcellus ENSCPOG00000020161 I 0.918
NR1I3 Cavia porcellus ENSCPOG00000015331 I 0.918
ENSCPOG00000006025 Cavia porcellus ENSCPOG00000006025 I 0.958
ENSDORG00000001701 Dipodomys ordii ENSDORG00000001701 I 0.874
Nr1i2 Dipodomys ordii ENSDORG00000003966 I 0.918
vdrb Gasterosteus aculeatus ENSGACG00000007975 I 0.945
vdra Gasterosteus aculeatus ENSGACG00000004763 I 0.945
VDR Felis catus ENSFCAG00000024594 I 0.958
NR1I2 Felis catus ENSFCAG00000006092 I 0.960
NR1I3 Felis catus ENSFCAG00000000497 I 0.889
NR1I2 Echinops telfairi ENSETEG00000018117 I 0.960
VDR Erinaceus europaeus ENSEEUG00000011116 I 0.958
NR1I3 Erinaceus europaeus ENSEEUG00000004981 I 0.894
NR1I3 Equus caballus ENSECAG00000020930 I 0.882
VDR Equus caballus ENSECAG00000015822 I 0.958
NR1I2 Equus caballus ENSECAG00000008728 I 0.960
VDR Callithrix jacchus ENSCJAG00000015018 I 0.958
NR1I2 Callithrix jacchus ENSCJAG00000008854 I 0.960
ENSAMEG00000013706 Ailuropoda melanoleuca ENSAMEG00000013706 I 0.958
ENSAMEG00000007006 Ailuropoda melanoleuca ENSAMEG00000007006 I 0.960
VDR Anolis carolinensis ENSACAG00000013485 I 0.945
ENSACAG00000001535 Anolis carolinensis ENSACAG00000001535 I 0.917
DAPPUDRAFT_319648 Daphnia pulex DAPPUDRAFT_319648 I 0.771
CPIJ002963 Culex quinquefasciatus CPIJ002963 I 0.775
BGIBMGA006767 Bombyx mori BGIBMGA006767 I 0.775
AGAP012211 Anopheles gambiae AGAP012211 I 0.775
ADAC008672 Anopheles darlingi ADAC008672 I 0.775
ACYPI001692 Acyrthosiphon pisum ACYPI001692 I 0.772
ECR Aedes aegypti AAEL009600 I 0.775
ENSAMEG00000015383 Ailuropoda melanoleuca ENSAMEG00000015383 I 0.935
ENSAMXG00000008863 Astyanax mexicanus ENSAMXG00000008863 I 0.929
NR1I3 Callithrix jacchus ENSCJAG00000004783 I 0.855
vdr-a Ciona intestinalis ENSCING00000020740 I 0.918
ENSCHOG00000008514 Choloepus hoffmanni ENSCHOG00000008514 I 0.958
NR1I3 Canis familiaris ENSCAFG00000012921 I 0.903
NR1I2 Canis familiaris ENSCAFG00000011094 I 0.934
VDR Canis familiaris ENSCAFG00000009103 I 0.958
NR1I2 Bos taurus ENSBTAG00000019557 I 0.949
VDR Bos taurus ENSBTAG00000016414 I 0.958
NR1I3 Bos taurus ENSBTAG00000009215 I 0.896
ENSAMXG00000019854 Astyanax mexicanus ENSAMXG00000019854 I 0.945
ENSAMXG00000012991 Astyanax mexicanus ENSAMXG00000012991 I 0.945
CpipJ_CPIJ002963 Culex pipiens CpipJ_CPIJ002963 I 0.775
ENSPMAG00000003695 Petromyzon marinus ENSPMAG00000003695 I 0.950
ENSONIG00000014385 Oreochromis niloticus ENSONIG00000014385 I 0.746
ENSONIG00000009200 Oreochromis niloticus ENSONIG00000009200 I 0.945
NR1I3 Otolemur garnettii ENSOGAG00000013738 I 0.861
NR1I2 Otolemur garnettii ENSOGAG00000006017 I 0.935
VDR Otolemur garnettii ENSOGAG00000005480 I 0.958
VDR Oryctolagus cuniculus ENSOCUG00000027507 I 0.958
NR1I3 Oryctolagus cuniculus ENSOCUG00000013537 I 0.884
NR1I2 Oryctolagus cuniculus ENSOCUG00000006125 I 0.859
ENSOARG00000019372 Ovis aries ENSOARG00000019372 I 0.958
ENSOARG00000009965 Ovis aries ENSOARG00000009965 I 0.828
ENSNLEG00000017900 Nomascus leucogenys ENSNLEG00000017900 I 0.958
ENSONIG00000019378 Oreochromis niloticus ENSONIG00000019378 I 0.945
NR1I3 Ochotona princeps ENSOPRG00000003455 I 0.869
ENSPFOG00000014233 Poecilia formosa ENSPFOG00000014233 I 0.945
ENSPFOG00000007256 Poecilia formosa ENSPFOG00000007256 I 0.848
ENSPFOG00000001655 Poecilia formosa ENSPFOG00000001655 I 0.945
NR1I3 Procavia capensis ENSPCAG00000013933 I 0.892
NR1I2 Procavia capensis ENSPCAG00000009674 I 0.917
ENSPANG00000014194 Papio anubis ENSPANG00000014194 I 0.846
ENSPANG00000011327 Papio anubis ENSPANG00000011327 I 0.958
nr1i2 Oryzias latipes ENSORLG00000017953 I 0.836
vdr Oryzias latipes ENSORLG00000016402 I 0.945
vdralpha Oryzias latipes ENSORLG00000001063 I 0.945
NR1I2 Ochotona princeps ENSOPRG00000010448 I 0.919
ENSNLEG00000014287 Nomascus leucogenys ENSNLEG00000014287 I 0.855
ENSNLEG00000005060 Nomascus leucogenys ENSNLEG00000005060 I 0.960
ENSMEUG00000000113 Macropus eugenii ENSMEUG00000000113 I 0.957
ENSLOCG00000005194 Lepisosteus oculatus ENSLOCG00000005194 I 0.945
NR1I2 Loxodonta africana ENSLAFG00000007829 I 0.914
VDR Loxodonta africana ENSLAFG00000006418 I 0.958
NR1I3 Loxodonta africana ENSLAFG00000001180 I 0.892
ENSLACG00000019104 Latimeria chalumnae ENSLACG00000019104 I 0.943
ENSLACG00000010334 Latimeria chalumnae ENSLACG00000010334 I 0.958
ENSGMOG00000019451 Gadus morhua ENSGMOG00000019451 I 0.945
ENSGMOG00000012720 Gadus morhua ENSGMOG00000012720 I 0.945
VDR Gorilla gorilla ENSGGOG00000016473 I 0.958
NR1I2 Gorilla gorilla ENSGGOG00000007361 I 0.960
ENSMEUG00000001987 Macropus eugenii ENSMEUG00000001987 I 0.917
ENSMEUG00000014791 Macropus eugenii ENSMEUG00000014791 I 0.958
ENSMPUG00000014388 Mustela putorius furo ENSMPUG00000014388 I 0.880
ENSMPUG00000000419 Mustela putorius furo ENSMPUG00000000419 I 0.958
ENSMODG00000028774 Monodelphis domestica ENSMODG00000028774 I 0.958
NR1I3 Monodelphis domestica ENSMODG00000005089 I 0.893
NR1I3 Macaca mulatta ENSMMUG00000018128 I 0.846
VDR Macaca mulatta ENSMMUG00000006727 I 0.958
NR1I2 Macaca mulatta ENSMMUG00000001976 I 0.960
NR1I2 Myotis lucifugus ENSMLUG00000002877 I 0.964
VDR Myotis lucifugus ENSMLUG00000000912 I 0.958
VDR Microcebus murinus ENSMICG00000009017 I 0.958
VDR Meleagris gallopavo ENSMGAG00000004846 I 0.959
NR1I3 Gorilla gorilla ENSGGOG00000005724 I 0.852