|
|
HHAL006987-PA
(Halyomorpha halys)
Paired box
|
TF Information |
|---|
| Pfam ID |
Interpro ID |
Gene ID |
CIS-BP ID |
Sequence source |
| PF00292 (PAX) |
IPR001523 |
HHAL006987-PA |
T312235_2.00 |
Misc (2018-Jan-19) |
| NCBI Gene Info:This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016] |
Directly determined binding motifs |
|---|
| Name/Motif ID |
Species |
Forward |
Reverse |
Type/Study/Study ID |
SR
Score |
DBD
Identity |
| No direct experiments |
|
|
|
|
|
Motifs from related TFs |
|---|
| Name/Motif ID |
Species |
Forward |
Reverse |
Type/Study/Study ID |
SR
Score |
DBD
Identity |
sv
M01302_2.00 |
Drosophila melanogaster |
NNNSCRBRDM |
KHYVYGSNNN |
PBM
Lambert et al.(2019)
pTH9773
|
0.903
|
0.903
|
sv
M03949_2.00 |
Drosophila melanogaster |
NBCRNYSAWGCGTGACS |
SGTCACGCWTSRNYGVN |
SELEX
Nitta et al.(2015)
sv_1
|
0.903
|
0.903
|
sv
M06438_2.00 |
Drosophila melanogaster |
RNYSRDSCGTRACNN |
NNGTYACGSHYSRNY |
B1H
Zhu et al.(2011)
sv_SOLEXA_5_FBgn0005561
|
0.903
|
0.903
|
pax2b
M02425_2.00 |
Danio rerio |
HVNYSRNSCR |
YGSNYSRNBD |
PBM
Weirauch et al.(2014)
pTH8679
|
0.792
|
0.792
|
pax2
M02428_2.00 |
Xenopus tropicalis |
NNNRNBCRNN |
NNYGVNYNNN |
PBM
Weirauch et al.(2014)
pTH8556
|
0.792
|
0.792
|
Pax5B
M01301_2.00 |
Gallus gallus |
NSNDTNNNN |
NNNNAHNSN |
PBM
Lambert et al.(2019)
pTH9781
|
0.750
|
0.750
|
PAX5
M03443_2.00 |
Homo sapiens |
RNBYANYSAWSCGTRACN |
NGTYACGSWTSRNTRVNY |
SELEX
Jolma et al.(2013)
PAX5_1
|
0.750
|
0.750
|
PAX5
M08160_2.00 |
Homo sapiens |
RDGCGTGACCNN |
NNGGTCACGCHY |
ChIP-seq
Mathelier et al.(2014)
MA0014.3
|
0.750
|
0.750
|
PAX5
M07995_2.00 |
Homo sapiens |
BCAVYSRDSCRKRRC |
GYYMYGSHYSRBTGV |
ChIP-seq
Gerstein et al.(2012)
GM12878_PAX5C20_HudsonAlpha
|
0.750
|
0.750
|
PAX5
M07996_2.00 |
Homo sapiens |
BCASYSRDSCRTRAC |
GTYAYGSHYSRSTGV |
ChIP-seq
Gerstein et al.(2012)
GM12878_PAX5N19_HudsonAlpha
|
0.750
|
0.750
|
PAX5
M07997_2.00 |
Homo sapiens |
CASYSRDSCRKRACN |
NGTYMYGSHYSRSTG |
ChIP-seq
Gerstein et al.(2012)
GM12891_PAX5C20_HudsonAlpha
|
0.750
|
0.750
|
PAX5
M07998_2.00 |
Homo sapiens |
BCASYSRDSCGKRRC |
GYYMCGSHYSRSTGV |
ChIP-seq
Gerstein et al.(2012)
GM12892_PAX5C20_HudsonAlpha
|
0.750
|
0.750
|
PAX5
M08227_2.00 |
Homo sapiens |
BCANYSRDGCGTRAM |
KTYACGCHYSRNTGV |
ChIP-seq
Contrino et al.(2012)
Mv108
|
0.750
|
0.750
|
PAX5
M08228_2.00 |
Homo sapiens |
AGCGTGRCYG |
CRGYCACGCT |
ChIP-seq
Contrino et al.(2012)
Mv109
|
0.750
|
0.750
|
PAX5
M09341_2.00 |
Homo sapiens |
SNVDGNKCARCVRAGCRDGAC |
GTCHYGCTYBGYTGMNCHBNS |
Misc
Kulakovskiy et al.(2013)
PAX5_HUMAN.H11MO.0.A
|
0.750
|
0.750
|
Pax5
M09342_2.00 |
Mus musculus |
VDRNBCAVYVRDSCRKRRM |
KYYMYGSHYBRBTGVNYHB |
Misc
Kulakovskiy et al.(2013)
PAX5_MOUSE.H11MO.0.A
|
0.750
|
0.750
|
PAX5
M09622_2.00 |
Homo sapiens |
BCASYSRDSCRTGRMN |
NKYCAYGSHYSRSTGV |
Misc
Heinz et al.(2010)
GM12878-PAX5_GSE32465_1
|
0.750
|
0.750
|
PAX5
M09623_2.00 |
Homo sapiens |
BCABNVRSCGTGAC |
GTCACGSYBNVTGV |
Misc
Heinz et al.(2010)
GM12878-PAX5_GSE32465_2
|
0.750
|
0.750
|
PAX5
M11208_2.00 |
Homo sapiens |
BCNNNRNKCANBGNWGNRKRGMSRSHNB |
VNDSYSKCYMYNCWNCVNTGMNYNNNGV |
Transfac
Matys et al.(2006)
V$PAX5_01
|
0.750
|
0.750
|
PAX5
M11209_2.00 |
Homo sapiens |
VRHVDGDNDBBTNRAGCGKRACVRYNVH |
DBNRYBGTYMCGCTYNAVVHNHCHBDYB |
Transfac
Matys et al.(2006)
V$PAX5_02
|
0.750
|
0.750
|
PAX5
M11210_2.00 |
Homo sapiens |
Transfac license required
|
Transfac license required
|
Transfac
Matys et al.(2006)
V$PAX5_06
|
0.750
|
0.750
|
PAX5
M11211_2.00 |
Homo sapiens |
Transfac license required
|
Transfac license required
|
Transfac
Matys et al.(2006)
V$PAX5_07
|
0.750
|
0.750
|
PAX5
M11212_2.00 |
Homo sapiens |
Transfac license required
|
Transfac license required
|
Transfac
Matys et al.(2006)
V$PAX5_Q6
|
0.750
|
0.750
|
PAX8
M05685_2.00 |
Homo sapiens |
NRNBYRNYSRWGCGTGACSN |
NSGTCACGCWYSRNYRVNYN |
SELEX
Yin et al.(2017)
PAX8_FL_HT-SELEX
|
0.736
|
0.736
|
Pax8
M09624_2.00 |
Rattus norvegicus |
BCAGBCADSCRKGVM |
KBCMYGSHTGVCTGV |
Misc
Heinz et al.(2010)
Thyroid-Pax8_GSE26938
|
0.736
|
0.736
|
PAX8
M11205_2.00 |
Homo sapiens |
Transfac license required
|
Transfac license required
|
Transfac
Matys et al.(2006)
V$PAX8_01
|
0.736
|
0.736
|
PAX8
M11206_2.00 |
Homo sapiens |
Transfac license required
|
Transfac license required
|
Transfac
Matys et al.(2006)
V$PAX8_B
|
0.736
|
0.736
|
PAX8
M05686_2.00 |
Homo sapiens |
NRNBCRNTSAWSCGYGACNN |
NNGTCRCGSWTSANYGVNYN |
SELEX
Yin et al.(2017)
PAX8_FL_Methyl-HT-SELEX
|
0.736
|
0.736
|
| For this family, TFs with SR scores > 0.700 will likely have a similar motif |