TF Information

ENSBTAP00000005261-D1 *(Bos grunniens)* Pipsqueak
Pfam ID	Interpro ID	Gene ID	CIS-BP ID	Sequence source
PF05225 (HTH_psq)	IPR007889	ENSBTAP00000005261-D1	T314434_2.00	GigaDB (2015-Oct-22)
NCBI Gene Info: This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016]
Directly determined binding motifs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
No direct experiments
Motifs from related TFs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
ENSMGAG00000009953 M02433_2.00	Meleagris gallopavo	NNNYNAAWNN	NNWTTNRNNN	PBM Weirauch et al.(2014) pTH8649	1.000	1.000
ENSACAG00000012432 M02430_2.00	Anolis carolinensis	NNNCNAAWNN	NNWTTNGNNN	PBM Weirauch et al.(2014) pTH9220	0.956	0.956
lcorl M02438_2.00	Xenopus tropicalis	NYCNAAWHN	NDWTTNGRN	PBM Weirauch et al.(2014) pTH8558	0.956	0.956
ENSORLG00000000044 M02434_2.00	Oryzias latipes	CCCAAAWT	AWTTTGGG	PBM Weirauch et al.(2014) pTH9275	0.911	0.911
ENSGACG00000007469 M02432_2.00	Gasterosteus aculeatus	NVNMGAWACH	DGTWTCKNBN	PBM Weirauch et al.(2014) pTH9179	0.822	0.822
ENSORLG00000007805 M02435_2.00	Oryzias latipes	SCNAAWNNNN	NNNNWTTNGS	PBM Weirauch et al.(2014) pTH9277	0.822	0.822
LCORL M02431_2.00	Choloepus hoffmanni	NNYNAAHNN	NNDTTNRNN	PBM Weirauch et al.(2014) pTH9253	0.800	0.800
For this family, TFs with SR scores > 0.778* will likely have a similar motif*