Pou3f3 (Mus musculus)
POU

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00157 (Pou) IPR000327 ENSMUSG00000045515 T316250_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Enables HMG box domain binding activity and sequence-specific DNA binding activity. Involved in several processes, including metanephric nephron epithelium development; negative regulation of apoptotic process; and regulation of transcription, DNA-templated. Acts upstream of or within several processes, including excretion; forebrain development; and positive regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in several structures, including alimentary system; brain; genitourinary system; phalanx; and sensory organ. Orthologous to human POU3F3 (POU class 3 homeobox 3). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Pou3f3
M00553_2.00		 Mus musculus
NNDMAWDN
NHWTKHNN		 PBM
Berger et al.(2008)
Pou3f3_3235		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Pou2f1
M00803_2.00 		Mus musculus
NHATWWNHNN
NNDNWWATDN		 PBM
Weirauch et al.(2013)
pTH4325 		0.778 0.778
For this family, TFs with SR scores > 0.700 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M00553_2.00 POU 19 90
M00553_2.00 Homeodomain 109 165

DNA Binding Domains

Protein ID Domain From To Sequence
ENSMUSP00000052088 POU 314 385

Links

Other POU family TFs
Other Mus musculus TFs

25 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
ENSDORG00000005303 Dipodomys ordii ENSDORG00000005303 I 1.000
pou3f3b Oryzias latipes ENSORLG00000001901 I 1.000
ENSMLUG00000001011 Myotis lucifugus ENSMLUG00000001011 I 0.944
OESDEN_22180 Oesophagostomum dentatum OESDEN_22180 I 0.917
TELCIR_24859 Teladorsagia circumcincta TELCIR_24859 I 0.917
Sjc_0006200 Schistosoma japonicum Sjc_0006200 I 0.903
GPUH_0000960301 Gongylonema pulchrum GPUH_0000960301 I 0.889
pou5f3 Tetraodon nigroviridis ENSTNIG00000003465 I 0.792
ENSTSYG00000009143 Tarsius syrichta ENSTSYG00000009143 I 0.778
ENSORLG00000014257 Oryzias latipes ENSORLG00000014257 I 0.778
ENSGMOG00000000005 Gadus morhua ENSGMOG00000000005 I 0.778
AMAM009299 Anopheles maculatus AMAM009299 I 0.769
POU2F2 Homo sapiens ENSG00000028277 D 0.764
POU2F2 Pteropus vampyrus ENSPVAG00000010621 I 0.764
ENSPPYG00000003972 Pongo abelii ENSPPYG00000003972 I 0.764
ENSDNOG00000046180 Dasypus novemcinctus ENSDNOG00000046180 I 0.764
POU2F3 Pan troglodytes ENSPTRG00000004391 I 0.764
ENSSARG00000008273 Sorex araneus ENSSARG00000008273 I 0.764
Brh_R009827 Buceros rhinoceros Brh_R009827 I 0.750
CAA36119 Xenopus laevis CAA36119 I 0.744
SBAD_0000845701 Soboliphyme baturini SBAD_0000845701 I 0.722
scaffold518-EXSNAP2012.7 Pristionchus exspectatus scaffold518-EXSNAP2012.7 N 0.708
augustus_masked-nMf.1.1.scaf21308-processed-gene-0.0 Meloidogyne floridensis augustus_masked-nMf.1.1.scaf21308-processed-gene-0.0 N 0.708
augustus_masked-nMf.1.1.scaf20785-processed-gene-0.0 Meloidogyne floridensis augustus_masked-nMf.1.1.scaf20785-processed-gene-0.0 N 0.708
ENSVPAG00000010276 Vicugna pacos ENSVPAG00000010276 I 0.706