Pou3f3 (Mus musculus)
POU

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00157 (Pou) IPR000327 ENSMUSG00000045515 T316250_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Enables HMG box domain binding activity and sequence-specific DNA binding activity. Involved in several processes, including metanephric nephron epithelium development; negative regulation of apoptotic process; and regulation of transcription, DNA-templated. Acts upstream of or within several processes, including excretion; forebrain development; and positive regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in several structures, including alimentary system; brain; genitourinary system; phalanx; and sensory organ. Orthologous to human POU3F3 (POU class 3 homeobox 3). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
Pou3f3
M00553_2.00
Mus musculus
NNDMAWDN

NHWTKHNN
PBM
Berger et al.(2008)
Pou3f3_3235
(Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
Pou2f1
M00803_2.00
Mus musculus
NHATWWNHNN

NNDNWWATDN
PBM
Weirauch et al.(2013)
pTH4325
0.778 0.778
For this family, TFs with SR scores > 0.700 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M00553_2.00 POU 19 90
M00553_2.00 Homeodomain 109 165

DNA Binding Domains

Protein ID Domain From To Sequence
ENSMUSP00000052088 POU 314 385

Links

Other POU family TFs
Other Mus musculus TFs

Invalid Input OrderBy

25 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action