nfkb1 (Danio rerio)
Rel

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00554 (RHD_DNA_bind) IPR011539 ENSDARG00000105261 T317109_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of transcription, DNA-templated. Predicted to be located in cytoplasm and nucleus. Is expressed in retina. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); common variable immunodeficiency; melanoma; prostate cancer; and tropical spastic paraparesis. Orthologous to several human genes including BICDL1 (BICD family like cargo adaptor 1). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
NFKB1
M03448_2.00 		Homo sapiens
MGGGGAWTCCCCT
AGGGGAWTCCCCK		 SELEX
Jolma et al.(2013)
NFKB1_1 		0.734 0.734
NFKB1
M05887_2.00 		Homo sapiens
NGGKRNTYYCCCN
NGGGRRANYMCCN		 SMiLE-seq
Isakova et al.(2017)
NFKB1 		0.734 0.734
NFKB1
M09348_2.00 		Homo sapiens
HYTTCCCY
RGGGAARD		 Misc
Kulakovskiy et al.(2013)
NFKB1_HUMAN.H11MO.0.A 		0.734 0.734
NFKB1
M11228_2.00 		Homo sapiens
GGGGATYCCC
GGGRATCCCC		 Transfac
Matys et al.(2006)
V$NFKAPPAB50_01 		0.734 0.734
NFKB1
M11229_2.00 		Homo sapiens
NGGGAHTYYCCM
KGGRRADTCCCN		 Transfac
Matys et al.(2006)
V$NFKB_C 		0.734 0.734
NFKB1
M11230_2.00 		Homo sapiens
DKGGGAMTTYCCNN
NNGGRAAKTCCCMH		 Transfac
Matys et al.(2006)
V$NFKB_Q6 		0.734 0.734
NFKB1
M11231_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$P50_Q6 		0.734 0.734
Nfkb1
M09358_2.00 		Mus musculus
GGGRNTTYCCC
GGGRAANYCCC		 Misc
Kulakovskiy et al.(2013)
NFKB1_MOUSE.H11MO.0.A 		0.728 0.728
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSDARP00000131701 Rel 49 247
ENSDARP00000135800 Rel 55 253

Links

Other Rel family TFs
Other Danio rerio TFs

65 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
NFKB2 Homo sapiens ENSG00000077150 D 0.931
NFKB1 Sus scrofa ENSSSCG00000030957 I 0.905
ENSLOCG00000012080 Lepisosteus oculatus ENSLOCG00000012080 I 0.864
ENSPFOG00000016918 Poecilia formosa ENSPFOG00000016918 I 0.864
ENSXMAG00000015369 Xiphophorus maculatus ENSXMAG00000015369 I 0.858
NFKB1 Gasterosteus aculeatus ENSGACG00000016876 I 0.858
ENSONIG00000004349 Oreochromis niloticus ENSONIG00000004349 I 0.846
ENSAMXG00000003341 Astyanax mexicanus ENSAMXG00000003341 I 0.828
ENSGMOG00000007506 Gadus morhua ENSGMOG00000007506 N 0.828
ENSOANG00000028755 Ornithorhynchus anatinus ENSOANG00000028755 I 0.809
NFKB1 Tetraodon nigroviridis ENSTNIG00000002693 N 0.805
Nfkb1 Mus musculus ENSMUSG00000028163 D 0.776
NFKB1 Homo sapiens ENSG00000109320 D 0.760
ENSLACG00000002751 Latimeria chalumnae ENSLACG00000002751 I 0.757
NFKB1 Gallus gallus ENSGALG00000012304 I 0.746
Pvit_05196 Pogona vitticeps Pvit_05196 I 0.746
NFKB1 Meleagris gallopavo ENSMGAG00000011299 I 0.746
NFKB1 Monodelphis domestica ENSMODG00000020672 I 0.740
Brh_R011794 Buceros rhinoceros Brh_R011794 I 0.740
ENSMEUG00000001334 Macropus eugenii ENSMEUG00000001334 I 0.740
ENSSHAG00000007374 Sarcophilus harrisii ENSSHAG00000007374 I 0.740
NFKB1 Vicugna pacos ENSVPAG00000000280 I 0.734
ENSPSIG00000008515 Pelodiscus sinensis ENSPSIG00000008515 I 0.734
ENSPPYG00000014965 Pongo abelii ENSPPYG00000014965 I 0.734
Aan_R012729 Calypte anna Aan_R012729 I 0.734
Afo_R015662 Aptenodytes forsteri Afo_R015662 I 0.734
ENSP00000226574 Macaca fascicularis ENSP00000226574 I 0.734
NFKB1 Pan troglodytes ENSPTRG00000016320 I 0.734
NFKB1 Tursiops truncatus ENSTTRG00000010852 I 0.734
Nfkb1 Rattus norvegicus ENSRNOG00000023258 I 0.734
ENSSTOG00000011445 Ictidomys tridecemlineatus ENSSTOG00000011445 I 0.734
NFKB1 Pteropus vampyrus ENSPVAG00000002722 I 0.734
NFKB1 Tupaia belangeri ENSTBEG00000003520 I 0.734
NFKB1 Taeniopygia guttata ENSTGUG00000003595 I 0.734
NFKB1 Ochotona princeps ENSOPRG00000005212 I 0.734
ENSMPUG00000009413 Mustela putorius furo ENSMPUG00000009413 I 0.734
ENSCSAG00000004049 Chlorocebus sabaeus ENSCSAG00000004049 I 0.734
NFKB1 Dasypus novemcinctus ENSDNOG00000006855 I 0.734
Nfkb1 Dipodomys ordii ENSDORG00000007447 I 0.734
NFKB1 Cavia porcellus ENSCPOG00000007789 I 0.734
NFKB1 Callithrix jacchus ENSCJAG00000015382 I 0.734
ENSAPLG00000013878 Anas platyrhynchos ENSAPLG00000013878 I 0.734
Tal_R004861 Tyto alba Tal_R004861 I 0.734
NFKB1 Canis familiaris ENSCAFG00000010730 I 0.734
ENSFALG00000008136 Ficedula albicollis ENSFALG00000008136 I 0.734
NFKB1 Felis catus ENSFCAG00000007557 I 0.734
Myotis_brandtii_NFKB1_10013135 Myotis brandtii Myotis_brandtii_NFKB1_10013135 I 0.734
ENSAMEG00000008882 Ailuropoda melanoleuca ENSAMEG00000008882 I 0.734
NFKB1 Oryctolagus cuniculus ENSOCUG00000021712 I 0.734
Gfo_R000994 Geospiza fortis Gfo_R000994 I 0.734
ENSNLEG00000013325 Nomascus leucogenys ENSNLEG00000013325 I 0.734
NFKB1 Gorilla gorilla ENSGGOG00000009071 I 0.734
NFKB1 Myotis lucifugus ENSMLUG00000005986 I 0.734
NFKB1 Macaca mulatta ENSMMUG00000003736 I 0.734
ENSBTAP00000027016-D1 Bos grunniens ENSBTAP00000027016-D1 I 0.728
ENSOARG00000012718 Ovis aries ENSOARG00000012718 I 0.728
NFKB1 Loxodonta africana ENSLAFG00000009344 I 0.728
NFKB1 Bos taurus ENSBTAG00000020270 I 0.728
Alligator_sinensis_CCG005309.1 Alligator sinensis Alligator_sinensis_CCG005309.1 I 0.728
NFKB1 Otolemur garnettii ENSOGAG00000012840 I 0.728
ENSPANG00000023882 Papio anubis ENSPANG00000023882 I 0.722
ENSOANG00000022123 Ornithorhynchus anatinus ENSOANG00000022123 I 0.714
nfkb1.L Xenopus laevis XB-GENE-985749 I 0.704
NFKB1 Procavia capensis ENSPCAG00000008172 I 0.704