Nfkb2 (Rattus norvegicus)
Rel

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00554 (RHD_DNA_bind) IPR011539 ENSRNOG00000019311 T317478_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in aging; response to cytokine; and response to lipopolysaccharide. Located in cytosol and nucleus. Used to study Parkinsonism. Human ortholog(s) of this gene implicated in common variable immunodeficiency. Orthologous to human NFKB2 (nuclear factor kappa B subunit 2). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Nfkb2
M09356_2.00 		Mus musculus
GGGRHTTYCCC
GGGRAADYCCC		 Misc
Kulakovskiy et al.(2013)
NFKB2_MOUSE.H11MO.0.C 		1.000 1.000
NFKB2
M03446_2.00 		Homo sapiens
NGGGGAWTCCCCB
VGGGGAWTCCCCN		 SELEX
Jolma et al.(2013)
NFKB2_1 		0.976 0.976
NFKB2
M05699_2.00 		Homo sapiens
HGGKRNWTCCCCN
NGGGGAWNYMCCD		 SELEX
Yin et al.(2017)
NFKB2_eDBD_HT-SELEX 		0.976 0.976
NFKB2
M09344_2.00 		Homo sapiens
GGGRHTTYCCC
GGGRAADYCCC		 Misc
Kulakovskiy et al.(2013)
NFKB2_HUMAN.H11MO.0.B 		0.976 0.976
NFKB2
M05700_2.00 		Homo sapiens
HGGKRNWTYCCCN
NGGGRAWNYMCCD		 SELEX
Yin et al.(2017)
NFKB2_eDBD_Methyl-HT-SELEX 		0.976 0.976
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSRNOP00000026235 Rel 40 220

Links

Other Rel family TFs
Other Rattus norvegicus TFs

Invalid Input OrderBy

57 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action