Rfx7 (Mus musculus)
RFX

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF02257 (RFX_DNA_binding) IPR003150 ENSMUSG00000037674 T318366_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human RFX7 (regulatory factor X7). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Rfx7
M00187_2.00		 Mus musculus
BGTHDYYRNN
NNYRRHDACV		 PBM
Badis et al.(2009)
Rfxdc2_3516		 (Direct) (Direct)
Rfx7
M00823_2.00		 Mus musculus
GTYRCYRNSB
VSNYRGYRAC		 PBM
Weirauch et al.(2013)
pTH3516		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
RFX7
M05729_2.00 		Homo sapiens
BGTTRCYRY
RYRGYAACV		 SELEX
Yin et al.(2017)
RFX7_eDBD_HT-SELEX 		0.793 1.000
RFX7
M05730_2.00 		Homo sapiens
BGTTGCYRB
VYRGCAACV		 SELEX
Yin et al.(2017)
RFX7_eDBD_Methyl-HT-SELEX 		0.793 1.000
RFX5
M03458_2.00 		Homo sapiens
BGTTRCYATRGYAACV
BGTTRCYATRGYAACV		 SELEX
Jolma et al.(2013)
RFX5_1 		0.710 0.620
RFX5
M03459_2.00 		Homo sapiens
BGTTGCYATGGYAACV
BGTTRCCATRGCAACV		 SELEX
Jolma et al.(2013)
RFX5_2 		0.710 0.620
RFX5
M03460_2.00 		Homo sapiens
BGTTGCYATGGYAACV
BGTTRCCATRGCAACV		 SELEX
Jolma et al.(2013)
RFX5_3 		0.710 0.620
RFX5
M05725_2.00 		Homo sapiens
BGTTRCYANGBGTTGCYRN
NYRGCAACVCNTRGYAACV		 SELEX
Yin et al.(2017)
RFX5_eDBD_HT-SELEX_1 		0.710 0.620
RFX5
M05726_2.00 		Homo sapiens
NYRVYAACSGTTRCYAN
NTRGYAACSGTTRBYRN		 SELEX
Yin et al.(2017)
RFX5_eDBD_HT-SELEX_2 		0.710 0.620
RFX5
M08009_2.00 		Homo sapiens
KCRBYDGTTRCYRRG
CYYRGYAACHRVYGM		 ChIP-seq
Gerstein et al.(2012)
GM12878_RFX5_Stanford 		0.710 0.620
RFX5
M08010_2.00 		Homo sapiens
DBVBYDGTTGCYRGGBVRR
YYBVCCYRGCAACHRVBVH		 ChIP-seq
Gerstein et al.(2012)
H1-hESC_RFX5_Stanford 		0.710 0.620
RFX5
M08011_2.00 		Homo sapiens
TCVBYDGTTDCYRDG
CHYRGHAACHRVBGA		 ChIP-seq
Gerstein et al.(2012)
HeLa-S3_RFX5_Stanford 		0.710 0.620
RFX5
M08012_2.00 		Homo sapiens
YDGTTRCYRKGBVRV
BYBVCMYRGYAACHR		 ChIP-seq
Gerstein et al.(2012)
HepG2_RFX5_Stanford 		0.710 0.620
RFX5
M09364_2.00 		Homo sapiens
VNNVBYDGTTGCYRKGNVRV
BYBNCMYRGCAACHRVBNNB		 Misc
Kulakovskiy et al.(2013)
RFX5_HUMAN.H11MO.0.A 		0.710 0.620
RFX5
M09629_2.00 		Homo sapiens
NDGTTRCYADGV
BCHTRGYAACHN		 Misc
Heinz et al.(2010)
GM12878-Rfx5_GSE31477 		0.710 0.620
RFX5
M11249_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$RFX5_03 		0.710 0.620
RFX5
M11250_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$RFX5_05 		0.710 0.620
RFX5
M05727_2.00 		Homo sapiens
BGTYRYYRNGBGTTGYYRN
NYRRCAACVCNYRRYRACV		 SELEX
Yin et al.(2017)
RFX5_eDBD_Methyl-HT-SELEX_1 		0.710 0.620
RFX5
M05728_2.00 		Homo sapiens
NTRGYAASSGTYRBYRN
NYRVYRACSSTTRCYAN		 SELEX
Yin et al.(2017)
RFX5_eDBD_Methyl-HT-SELEX_2 		0.710 0.620
For this family, TFs with SR scores > 0.650 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M00187_2.00 RFX 26 104
M00823_2.00 RFX 26 104

DNA Binding Domains

Protein ID Domain From To Sequence
ENSMUSP00000091338 RFX 105 183
ENSMUSP00000127192 RFX 105 183
ENSMUSP00000138957 RFX 105 183
ENSMUSP00000139195 RFX 105 183

Links

Other RFX family TFs
Other Mus musculus TFs

Invalid Input OrderBy

233 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action