ENSP00000371434 (Macaca fascicularis)
RFX

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source
PF02257 (RFX_DNA_binding) IPR003150 ENSP00000371434 T318983_2.00 GigaDB (2015-Oct-22)
NCBI Gene Info:
This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X2, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with other RFX family members. Multiple transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2013]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
RFX3
M03452_2.00
Homo sapiens
NGTTRCCATGGHAACV

BGTTDCCATGGYAACN
SELEX
Jolma et al.(2013)
RFX3_1
0.779 1.000
RFX3
M03453_2.00
Homo sapiens
BGTTGCTARGCAACS

SGTTGCYTAGCAACV
SELEX
Jolma et al.(2013)
RFX3_2
0.779 1.000
RFX3
M02750_2.00
Homo sapiens
GTTRYYATGG

CCATRRYAAC
SELEX
Jolma et al.(2010)
RFX3_dimer
0.779 1.000
RFX3
M05715_2.00
Homo sapiens
NGTTRYYATRRYAACN

NGTTRYYATRRYAACN
SELEX
Yin et al.(2017)
RFX3_eDBD_HT-SELEX_1
0.779 1.000
RFX3
M05716_2.00
Homo sapiens
BGTTGCTARGCAACS

SGTTGCYTAGCAACV
SELEX
Yin et al.(2017)
RFX3_eDBD_HT-SELEX_2
0.779 1.000
RFX3
M09361_2.00
Homo sapiens
BGTTRCCATGGYRN

NYRCCATGGYAACV
Misc
Kulakovskiy et al.(2013)
RFX3_HUMAN.H11MO.0.B
0.779 1.000
RFX3
M09627_2.00
Homo sapiens
BNGTTGCCATGGCAAC

GTTGCCATGGCAACNV
Misc
Heinz et al.(2010)
K562-RFX3_SRA012198
0.779 1.000
RFX3
M05717_2.00
Homo sapiens
BGTTRYYATRRYAACV

BGTTRYYATRRYAACV
SELEX
Yin et al.(2017)
RFX3_eDBD_Methyl-HT-SELEX_1
0.779 1.000
RFX3
M05718_2.00
Homo sapiens
BGTTGCTARGCAACV

BGTTGCYTAGCAACV
SELEX
Yin et al.(2017)
RFX3_eDBD_Methyl-HT-SELEX_2
0.779 1.000
RFX2
M03454_2.00
Homo sapiens
BGTTRCCATGGYAACV

BGTTRCCATGGYAACV
SELEX
Jolma et al.(2013)
RFX2_1
0.775 0.962
RFX2
M03455_2.00
Homo sapiens
SGTTGCTARGCAACS

SGTTGCYTAGCAACS
SELEX
Jolma et al.(2013)
RFX2_2
0.775 0.962
RFX2
M05719_2.00
Homo sapiens
NGTWDYYATRRHWACN

NGTWDYYATRRHWACN
SELEX
Yin et al.(2017)
RFX2_eDBD_HT-SELEX
0.775 0.962
RFX2
M09362_2.00
Homo sapiens
YNGTTGCCATGGVRACVV

BBGTYBCCATGGCAACNR
Misc
Kulakovskiy et al.(2013)
RFX2_HUMAN.H11MO.0.A
0.775 0.962
RFX2
M09628_2.00
Homo sapiens
BGTTKCCATGGMAAC

GTTKCCATGGMAACV
Misc
Heinz et al.(2010)
LoVo-RFX2_GSE49402
0.775 0.962
RFX2
M05720_2.00
Homo sapiens
BGTTRCCATGRYAACV

BGTTRYCATGGYAACV
SELEX
Yin et al.(2017)
RFX2_eDBD_Methyl-HT-SELEX
0.775 0.962
Rfx2
M03461_2.00
Mus musculus
BGTTRCCATGGYAACV

BGTTRCCATGGYAACV
SELEX
Jolma et al.(2013)
Rfx2_1
0.773 0.949
Rfx2
M03462_2.00
Mus musculus
SGTTGCTARGCAACV

BGTTGCYTAGCAACS
SELEX
Jolma et al.(2013)
Rfx2_2
0.773 0.949
Rfx2
M05888_2.00
Mus musculus
NGTTRCYATGGHDAY

RTHDCCATRGYAACN
SMiLE-seq
Isakova et al.(2017)
RFX2
0.773 0.949
Rfx2
M09366_2.00
Mus musculus
NBYBGTYNCCMTGGCAACNSSS

SSSNGTTGCCAKGGNRACVRVN
Misc
Kulakovskiy et al.(2013)
RFX2_MOUSE.H11MO.0.A
0.773 0.949
Rfx3
M00188_2.00
Mus musculus
SNTRRHDACN

NGTHDYYANS
PBM
Badis et al.(2009)
Rfx3_3961
0.768 0.962
Rfx3
M03463_2.00
Mus musculus
SGTTRCCATGGYAACS

SGTTRCCATGGYAACS
SELEX
Jolma et al.(2013)
Rfx3_1
0.768 0.962
Rfx3
M09368_2.00
Mus musculus
BBGTTGCCATGGNRAC

GTYNCCATGGCAACVV
Misc
Kulakovskiy et al.(2013)
RFX3_MOUSE.H11MO.0.C
0.768 0.962
RFX2
M02449_2.00
Homo sapiens
BGTHRYYADG

CHTRRYDACV
PBM
Weirauch et al.(2014)
pTH9194
0.764 0.923
RFX2
M02450_2.00
Ornithorhynchus anatinus
NGTHRYYANV

BNTRRYDACN
PBM
Weirauch et al.(2014)
pTH9269
0.764 0.923
RFX1
M02447_2.00
Anolis carolinensis
GTHRCYANGN

NCNTRGYDAC
PBM
Weirauch et al.(2014)
pTH9223
0.762 0.846
RFX1
M02451_2.00
Tetraodon nigroviridis
GTHDYYANGN

NCNTRRHDAC
PBM
Weirauch et al.(2014)
pTH9385
0.762 0.846
RFX1
M05723_2.00
Homo sapiens
BGTTRYCATGRYAACV

BGTTRYCATGRYAACV
SELEX
Yin et al.(2017)
RFX1_eDBD_HT-SELEX
0.762 0.846
Rfx1
M08162_2.00
Mus musculus
GTTGCYADGGNRAC

GTYNCCHTRGCAAC
ChIP-seq
Mathelier et al.(2014)
MA0509.1
0.762 0.846
RFX1
M09363_2.00
Homo sapiens
BBBSSNGTTGCCADGGNRMCVV

BBGKYNCCHTGGCAACNSSVVV
Misc
Kulakovskiy et al.(2013)
RFX1_HUMAN.H11MO.0.B
0.762 0.846
Rfx1
M09367_2.00
Mus musculus
BBBSSNGTTGCCADGGNRMCVV

BBGKYNCCHTGGCAACNSSVVV
Misc
Kulakovskiy et al.(2013)
RFX1_MOUSE.H11MO.0.A
0.762 0.846
RFX1
M11245_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$EFC_Q6
0.762 0.846
RFX1
M11246_2.00
Homo sapiens
HNGTTRCYWVGYDMYNN

NNRKHRCBWRGYAACND
Transfac
Matys et al.(2006)
V$RFX1_01
0.762 0.846
RFX1
M11247_2.00
Homo sapiens
HNGTTRCYWBVGYDMYNN

NNRKHRCBVWRGYAACND
Transfac
Matys et al.(2006)
V$RFX1_02
0.762 0.846
RFX1
M11248_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$RFX1_Q6
0.762 0.846
RFX1
M05724_2.00
Homo sapiens
BGTWRYCATGRYWACV

BGTWRYCATGRYWACV
SELEX
Yin et al.(2017)
RFX1_eDBD_Methyl-HT-SELEX
0.762 0.846
GB41876
M02453_2.00
Apis mellifera
GTHDCYANVN

NBNTRGHDAC
PBM
Weirauch et al.(2014)
pTH9226
0.760 0.859
XP_002157607.1
M02456_2.00
Hydra magnipapillata
GTHDYYDNVN

NBNHRRHDAC
PBM
Weirauch et al.(2014)
pTH9199
0.757 0.808
G4VLF2_SCHMA
M02452_2.00
Schistosoma mansoni
GTTGCTAD

HTAGCAAC
PBM
Weirauch et al.(2014)
pTH8587
0.756 0.821
Sjc_0102030
M02455_2.00
Schistosoma japonicum
GTTRCYANG

CNTRGYAAC
PBM
Weirauch et al.(2014)
pTH9285
0.755 0.808
Rfx
M03959_2.00
Drosophila melanogaster
NGTHRCYATRGYDACN

NGTHRCYATRGYDACN
SELEX
Nitta et al.(2015)
Rfx_1
0.751 0.808
Rfx
M03960_2.00
Drosophila melanogaster
GTTGCTARGCAAC

GTTGCYTAGCAAC
SELEX
Nitta et al.(2015)
Rfx_2
0.751 0.808
Rfx
M03961_2.00
Drosophila melanogaster
BGTWRCCATGGYWACV

BGTWRCCATGGYWACV
SELEX
Nitta et al.(2015)
Rfx_3
0.751 0.808
Rfx
M03962_2.00
Drosophila melanogaster
GTTRCYAWTRGYAAC

GTTRCYAWTRGYAAC
SELEX
Nitta et al.(2015)
Rfx_4
0.751 0.808
Rfx
M03963_2.00
Drosophila melanogaster
GTTGCTARGCAAC

GTTGCYTAGCAAC
SELEX
Nitta et al.(2015)
Rfx_5
0.751 0.808
PHUM046580
M02454_2.00
Pediculus humanus
NGTHDCYANV

BNTRGHDACN
PBM
Weirauch et al.(2014)
pTH9278
0.742 0.833
daf-19
M00709_2.00
Caenorhabditis elegans
SGTTRCTADG

CHTAGYAACS
PBM
Narasimhan et al.(2015)
pTH10021
0.729 0.679
RFX4
M02448_2.00
Cavia porcellus
GTHDYYNNGN

NCNNRRHDAC
PBM
Weirauch et al.(2014)
pTH9249
0.704 0.654
Rfx4
M00186_2.00
Mus musculus
GTHDYYNNSN

NSNNRRHDAC
PBM
Badis et al.(2009)
Rfx4_3761
0.704 0.654
RFX4
M03456_2.00
Homo sapiens
NGTWRYCATRGHWACN

NGTWDCYATGRYWACN
SELEX
Jolma et al.(2013)
RFX4_1
0.704 0.654
RFX4
M03457_2.00
Homo sapiens
NGTTGCYRRGCAACS

SGTTGCYYRGCAACN
SELEX
Jolma et al.(2013)
RFX4_2
0.704 0.654
RFX4
M05721_2.00
Homo sapiens
BGTWRYCATGRYWACV

BGTWRYCATGRYWACV
SELEX
Yin et al.(2017)
RFX4_eDBD_HT-SELEX
0.704 0.654
RFX4
M05722_2.00
Homo sapiens
BGTWRYCATGRYWACV

BGTWRYCATGRYWACV
SELEX
Yin et al.(2017)
RFX4_eDBD_Methyl-HT-SELEX
0.704 0.654
Rfx6
M09365_2.00
Mus musculus
BDGTWKCYNDG

CHNRGMAACHV
Misc
Kulakovskiy et al.(2013)
RFX6_MOUSE.H11MO.0.C
0.684 0.615
RFX1
M00066_2.00
Saccharomyces cerevisiae
NSGTTGCYAN

NTRGCAACSN
PBM
Badis et al.(2008)
RFX1_4537
0.651 0.410
RFX1
M07494_2.00
Saccharomyces cerevisiae
BGTTRCYA

TRGYAACV
PBM, CSA and or DIP-chip
Mathelier et al.(2014)
MA0365.1
0.651 0.410
RFX1
M08600_2.00
Saccharomyces cerevisiae
CGTYRBYAYRGYWACM

KGTWRCYRTRVYRACG
Misc
DeBoer et al.(2011)
YLR176C_1478
0.651 0.410
RFX1
M08601_2.00
Saccharomyces cerevisiae
BGTTRCYA

TRGYAACV
Misc
DeBoer et al.(2011)
YLR176C_496
0.651 0.410
RFX1
M11251_2.00
Saccharomyces cerevisiae Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
F$RFX1_02
0.651 0.410
For this family, TFs with SR scores > 0.650 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000371434 RFX 181 258

Links

Other RFX family TFs
Other Macaca fascicularis TFs

693 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action