Deaf1 (Drosophila melanogaster)
SAND

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF01342 (SAND) IPR000770 FBgn0013799 T321961_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Enables DNA-binding transcription factor activity and sequence-specific DNA binding activity. Involved in embryo development; regulation of immune response; and regulation of transcription, DNA-templated. Located in nucleus and polytene chromosome. Is expressed in several structures, including embryonic/larval midgut; embryonic/larval nervous system; extended germ band embryo; and presumptive embryonic/larval system. Human ortholog(s) of this gene implicated in Vulto-van Silfout-de Vries syndrome. Orthologous to human DEAF1 (DEAF1 transcription factor). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Deaf1
M06445_2.00		 Drosophila melanogaster
VMCGAR
YTCGKB		 B1H
Zhu et al.(2011)
Deaf1_FlyReg_FBgn0013799		 (Direct) (Direct)
Deaf1
M07544_2.00		 Drosophila melanogaster
VMCGAR
YTCGKB		 DNaseI footprinting
Mathelier et al.(2014)
MA0185.1		 (Direct) (Direct)
Deaf1
M11268_2.00		 Drosophila melanogaster Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
I$DEAF_01		 (Direct) (Direct)
Deaf1
M11269_2.00		 Drosophila melanogaster Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
I$DEAF1_Q6		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
For this family, TFs with SR scores > 0.843 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
FBpp0074651 SAND 215 290
FBpp0100128 SAND 215 290
FBpp0302624 SAND 178 253
FBpp0304463 SAND 215 290
FBpp0304972 SAND 178 253

Links

Other SAND family TFs
Other Drosophila melanogaster TFs

Invalid Input OrderBy

44 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action