ENSCSAVG00000006480 (Ciona savignyi)
SMAD

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF03165 (MH1) IPR003619 ENSCSAVG00000006480 T324550_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Smad4
M05889_2.00 		Mus musculus
KCYAGACR
YGTCTRGM		 SMiLE-seq
Isakova et al.(2017)
Smad4 		0.922 0.922
SMAD4
M09377_2.00 		Homo sapiens
DRGTGNSAGACWN
NWGTCTSNCACYH		 Misc
Kulakovskiy et al.(2013)
SMAD4_HUMAN.H11MO.0.B 		0.922 0.922
Smad4
M09382_2.00 		Mus musculus
DGWGNBAGVCWN
NWGBCTVNCWCH		 Misc
Kulakovskiy et al.(2013)
SMAD4_MOUSE.H11MO.0.A 		0.922 0.922
SMAD4
M09634_2.00 		Homo sapiens
NNNYGTCTGS
SCAGACRNNN		 Misc
Heinz et al.(2010)
ESC-SMAD4_GSE29422 		0.922 0.922
SMAD4
M11275_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD4_Q4 		0.922 0.922
SMAD4
M11276_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD4_Q6_01 		0.922 0.922
SMAD4
M11277_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD4_Q6 		0.922 0.922
Med
M06447_2.00 		Drosophila melanogaster
KCGBCDKKSHVT
ABDSMMHGVCGM		 B1H
Zhu et al.(2011)
Med_FlyReg_FBgn0011655 		0.912 0.912
Med
M09693_2.00 		Drosophila melanogaster
YYBYVYCTGYY
RRCAGRBRVRR		 Misc
Kulakovskiy et al.(2009)
Med 		0.912 0.912
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSCSAVP00000011075 SMAD 33 134
ENSCSAVP00000011076 SMAD 33 134
ENSCSAVP00000011077 SMAD 33 134
ENSCSAVP00000011078 SMAD 32 133
ENSCSAVP00000011079 SMAD 31 132
ENSCSAVP00000011080 SMAD 26 127
ENSCSAVP00000011081 SMAD 26 127

Links

Other SMAD family TFs
Other Ciona savignyi TFs

210 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
smad4 Ciona intestinalis ENSCING00000005559 I 0.990
SMAD4 Homo sapiens ENSG00000141646 D 0.964
ENSAMXG00000019219 Astyanax mexicanus ENSAMXG00000019219 I 0.931
ENSPFOG00000018987 Poecilia formosa ENSPFOG00000018987 I 0.931
ENSXMAG00000015245 Xiphophorus maculatus ENSXMAG00000015245 I 0.931
smad4a Oryzias latipes ENSORLG00000005020 I 0.931
smad4a Danio rerio ENSDARG00000075226 I 0.931
ENSLACG00000007810 Latimeria chalumnae ENSLACG00000007810 I 0.931
SMAD4 Gorilla gorilla ENSGGOG00000013662 I 0.922
ENSGMOG00000005844 Gadus morhua ENSGMOG00000005844 I 0.922
ENSPPYG00000009165 Pongo abelii ENSPPYG00000009165 I 0.922
ENSPSIG00000014614 Pelodiscus sinensis ENSPSIG00000014614 I 0.922
Smad4 Rattus norvegicus ENSRNOG00000051965 I 0.922
SMAD4 Equus caballus ENSECAG00000017857 I 0.922
SMAD4 Dasypus novemcinctus ENSDNOG00000005063 I 0.922
SMAD4 Echinops telfairi ENSETEG00000007750 I 0.922
SMAD4 Felis catus ENSFCAG00000005257 I 0.922
SMAD4 Pan troglodytes ENSPTRG00000010028 I 0.922
ENSTSYG00000009792 Tarsius syrichta ENSTSYG00000009792 I 0.922
smad4a Gasterosteus aculeatus ENSGACG00000007495 I 0.922
SMAD4 Vicugna pacos ENSVPAG00000006757 I 0.922
SMAD4 Oryctolagus cuniculus ENSOCUG00000003929 I 0.922
ENSOARG00000004662 Ovis aries ENSOARG00000004662 I 0.922
SMAD4 Otolemur garnettii ENSOGAG00000012081 I 0.922
ENSPANG00000024703 Papio anubis ENSPANG00000024703 I 0.922
SMAD4 Ochotona princeps ENSOPRG00000013601 I 0.922
ENSONIG00000015035 Oreochromis niloticus ENSONIG00000015035 I 0.922
ENSOANG00000030959 Ornithorhynchus anatinus ENSOANG00000030959 I 0.922
SMAD4 Ornithorhynchus anatinus ENSOANG00000008117 I 0.922
SMAD4 Macaca mulatta ENSMMUG00000018334 I 0.922
SMAD4 Myotis lucifugus ENSMLUG00000013944 I 0.922
SMAD4 Monodelphis domestica ENSMODG00000010995 I 0.922
ENSMPUG00000008776 Mustela putorius furo ENSMPUG00000008776 I 0.922
ENSNLEG00000011859 Nomascus leucogenys ENSNLEG00000011859 I 0.922
Smad4 Mus musculus ENSMUSG00000024515 D 0.922
SMAD4 Loxodonta africana ENSLAFG00000012595 I 0.922
ENSSHAG00000010344 Sarcophilus harrisii ENSSHAG00000010344 I 0.922
Gfo_R016223 Geospiza fortis Gfo_R016223 I 0.922
Myotis_brandtii_Smad4_10005924 Myotis brandtii Myotis_brandtii_Smad4_10005924 I 0.922
Gfo_R011803 Geospiza fortis Gfo_R011803 I 0.922
ENSP00000381452 Macaca fascicularis ENSP00000381452 I 0.922
Cmyd_10005540 Chelonia mydas Cmyd_10005540 I 0.922
ENSP00000341551-D1 Bos grunniens ENSP00000341551-D1 I 0.922
Ogr06720 Ophisaurus gracilis Ogr06720 I 0.922
Ogr14199 Ophisaurus gracilis Ogr14199 I 0.922
smad4.1 Xenopus tropicalis XB-GENE-485691 I 0.922
SMAD4 Tupaia belangeri ENSTBEG00000014105 I 0.922
LDEC015949 Leptinotarsa decemlineata LDEC015949 I 0.922
ENSSTOG00000028580 Ictidomys tridecemlineatus ENSSTOG00000028580 I 0.922
Pvit_01119 Pogona vitticeps Pvit_01119 I 0.922
AAH84196 Xenopus laevis AAH84196 I 0.922
Brh_R010414 Buceros rhinoceros Brh_R010414 I 0.922
Alligator_sinensis_CCG008910.1 Alligator sinensis Alligator_sinensis_CCG008910.1 I 0.922
SMAD4 Callithrix jacchus ENSCJAG00000001910 I 0.922
SMAD4 Choloepus hoffmanni ENSCHOG00000000860 I 0.922
SMAD4 Cavia porcellus ENSCPOG00000006470 I 0.922
ENSCSAG00000018094 Chlorocebus sabaeus ENSCSAG00000018094 I 0.922
SMAD4 Sus scrofa ENSSSCG00000004524 I 0.922
TC010848 Tribolium castaneum TC010848 I 0.922
SMAD4 Canis familiaris ENSCAFG00000000164 I 0.922
SMAD4 Bos taurus ENSBTAG00000006919 I 0.922
ENSAMEG00000002899 Ailuropoda melanoleuca ENSAMEG00000002899 I 0.922
SMAD4 Anolis carolinensis ENSACAG00000010186 I 0.922
smad4.1.L Xenopus laevis XB-GENE-865543 I 0.922
Afo_R008709 Aptenodytes forsteri Afo_R008709 I 0.922
YQE_06624 Dendroctonus ponderosae YQE_06624 I 0.922
ENSAPLG00000003924 Anas platyrhynchos ENSAPLG00000003924 I 0.922
Smad4 Dipodomys ordii ENSDORG00000009089 I 0.921
gb:cr929477 Takifugu rubripes ENSTRUG00000011769 I 0.912
ENSXMAG00000005051 Xiphophorus maculatus ENSXMAG00000005051 I 0.912
Med Drosophila melanogaster FBgn0011655 D 0.912
SMAD4 Takifugu rubripes ENSTRUG00000014045 I 0.912
L798_13939 Zootermopsis nevadensis L798_13939 I 0.912
SMAR013850 Strigamia maritima SMAR013850 I 0.912
PHUM002670 Pediculus humanus PHUM002670 I 0.912
SMAD4 Tetraodon nigroviridis ENSTNIG00000009050 I 0.912
LCUP007928 Lucilia cuprina LCUP007928 I 0.912
smad4.2.S Xenopus laevis XB-GENE-5995204 I 0.912
MDOA012885 Musca domestica MDOA012885 I 0.912
smad4.2.L Xenopus laevis XB-GENE-6256010 I 0.912
GE10952 Drosophila yakuba FBgn0228782 I 0.912
GK11724 Drosophila willistoni FBgn0213735 I 0.912
GG11819 Drosophila erecta FBgn0104114 I 0.912
GF22974 Drosophila ananassae FBgn0099968 I 0.912
GH18642 Drosophila grimshawi FBgn0126109 I 0.912
GI23400 Drosophila mojavensis FBgn0146126 I 0.912
GJ23092 Drosophila virilis FBgn0210194 I 0.912
GM16436 Drosophila sechellia FBgn0171351 I 0.912
GA14643 Drosophila pseudoobscura FBgn0074670 I 0.912
GL23637 Drosophila persimilis FBgn0161227 I 0.912
SMAD4 Danio rerio ENSDARG00000012649 I 0.912
AAEL013896 Aedes aegypti AAEL013896 I 0.912
ENSPFOG00000019807 Poecilia formosa ENSPFOG00000019807 I 0.912
SMAD4 Oryzias latipes ENSORLG00000007703 I 0.912
gb:cr929477 Tetraodon nigroviridis ENSTNIG00000003193 I 0.912
ACUA025512 Anopheles culicifacies ACUA025512 I 0.902
ACOM037505 Anopheles coluzzii ACOM037505 I 0.902
SINV15516 Solenopsis invicta SINV15516 I 0.902
BGIBMGA010110 Bombyx mori BGIBMGA010110 I 0.902
NV12984 Nasonia vitripennis NV12984 I 0.902
AQUA009305 Anopheles quadriannulatus AQUA009305 I 0.902
MCINX014520 Melitaea cinxia MCINX014520 I 0.902
ADIR002761 Anopheles dirus ADIR002761 I 0.902
Hsal_09633--XP_392838.3_APIME Harpegnathos saltator Hsal_09633--XP_392838.3_APIME I 0.902
ASTEI00079 Anopheles stephensi ASTEI00079 I 0.902
CPIJ002563 Culex quinquefasciatus CPIJ002563 I 0.902
DAPPUDRAFT_304115 Daphnia pulex DAPPUDRAFT_304115 I 0.902
AEPI002385 Anopheles epiroticus AEPI002385 I 0.902
AFAF011208 Anopheles farauti AFAF011208 I 0.902
AFUN009864 Anopheles funestus AFUN009864 I 0.902
AMAM019778 Anopheles maculatus AMAM019778 I 0.902
BGLB014287 Biomphalaria glabrata BGLB014287 I 0.902
AMEM015931 Anopheles merus AMEM015931 I 0.902
Cflo_07183--XP_392838.3_APIME Camponotus floridanus Cflo_07183--XP_392838.3_APIME I 0.902
AMIN000723 Anopheles minimus AMIN000723 I 0.902
KGM_12572 Danaus plexippus KGM_12572 I 0.902
CpipJ_CPIJ002563 Culex pipiens CpipJ_CPIJ002563 I 0.902
e_gw.452.68.1 Branchiostoma floridae e_gw.452.68.1 I 0.902
PPAI002168 Phlebotomus papatasi PPAI002168 I 0.902
ENSONIG00000014036 Oreochromis niloticus ENSONIG00000014036 I 0.902
ENSPMAG00000008404 Petromyzon marinus ENSPMAG00000008404 I 0.902
AARA004719 Anopheles arabiensis AARA004719 I 0.902
ENSGACG00000016858 Gasterosteus aculeatus ENSGACG00000016858 I 0.902
AATE010695 Anopheles atroparvus AATE010695 I 0.902
AGAP002902 Anopheles gambiae AGAP002902 I 0.902
HMEL002203 Heliconius melpomene HMEL002203 I 0.902
ISCW018468 Ixodes scapularis ISCW018468 I 0.902
ACHR000067 Anopheles christyi ACHR000067 I 0.902
LLOJ008806 Lutzomyia longipalpis LLOJ008806 I 0.902
GB50071 Apis mellifera GB50071 I 0.902
ENSAMXG00000017275 Astyanax mexicanus ENSAMXG00000017275 I 0.892
ACYPI000365 Acyrthosiphon pisum ACYPI000365 I 0.892
AALB009485 Anopheles albimanus AALB009485 I 0.892
CLEC002594 Cimex lectularius CLEC002594 I 0.892
si:dkey-222b8.1 Takifugu rubripes ENSTRUG00000004163 I 0.892
ADAC007516 Anopheles darlingi ADAC007516 I 0.892
HHAL000394-PA Halyomorpha halys HHAL000394-PA I 0.892
SPU_004287 Strongylocentrotus purpuratus SPU_004287 I 0.892
ENSGMOG00000013964 Gadus morhua ENSGMOG00000013964 I 0.892
ENSMEUG00000001823 Macropus eugenii ENSMEUG00000001823 I 0.892
ENSONIG00000001557 Oreochromis niloticus ENSONIG00000001557 I 0.892
ENSONIG00000010360 Oreochromis niloticus ENSONIG00000010360 I 0.892
RPRC010188 Rhodnius prolixus RPRC010188 I 0.892
si:dkey-222b8.1 Gasterosteus aculeatus ENSGACG00000000538 I 0.892
si:dkey-222b8.1 Danio rerio ENSDARG00000045094 I 0.892
ENSAMXG00000018339 Astyanax mexicanus ENSAMXG00000018339 I 0.892
CapteG179368 Capitella teleta CapteG179368 I 0.882
fgenesh2_pg.scaffold_230000050 Branchiostoma floridae fgenesh2_pg.scaffold_230000050 I 0.882
Ocbimv22032358m.g Octopus bimaculoides Ocbimv22032358m.g I 0.882
Alligator_sinensis_CCG001823.1 Alligator sinensis Alligator_sinensis_CCG001823.1 I 0.882
HHAL000393-PA Halyomorpha halys HHAL000393-PA I 0.882
ENSGMOG00000000297 Gadus morhua ENSGMOG00000000297 I 0.882
si:dkey-239n17.4 Danio rerio ENSDARG00000070428 I 0.882
NEMVEDRAFT_v1g248037 Nematostella vectensis NEMVEDRAFT_v1g248037 I 0.882
ENSPMAG00000009414 Petromyzon marinus ENSPMAG00000009414 I 0.873
ENSPFOG00000019867 Poecilia formosa ENSPFOG00000019867 I 0.873
LotgiG131078 Lottia gigantea LotgiG131078 I 0.873
XP_002161797.1 Hydra magnipapillata XP_002161797.1 I 0.863
YQE_08737 Dendroctonus ponderosae YQE_08737 I 0.863
si:dkey-222b8.1 Tetraodon nigroviridis ENSTNIG00000005007 I 0.853
ACYPI003759 Acyrthosiphon pisum ACYPI003759 I 0.853
ENSGACG00000003171 Gasterosteus aculeatus ENSGACG00000003171 I 0.853
tetur10g00400 Tetranychus urticae tetur10g00400 I 0.853
HelroG88197 Helobdella robusta HelroG88197 I 0.853
ACYPI008450 Acyrthosiphon pisum ACYPI008450 I 0.853
SPU_017971 Strongylocentrotus purpuratus SPU_017971 I 0.836
Aqu1.215834 Amphimedon queenslandica Aqu1.215834 I 0.824
ACYPI005550 Acyrthosiphon pisum ACYPI005550 I 0.824
ML02191a Mnemiopsis leidyi ML02191a I 0.824
Aqu1.215833 Amphimedon queenslandica Aqu1.215833 I 0.824
Aan_R014474 Calypte anna Aan_R014474 I 0.810
ECPE_0001832001 Echinostoma caproni ECPE_0001832001 I 0.804
T265_11013 Opisthorchis viverrini T265_11013 I 0.794
CGI_10000594 Crassostrea gigas CGI_10000594 I 0.786
TriadG30731 Trichoplax adhaerens TriadG30731 I 0.784
TMUE_s0006012700 Trichuris muris TMUE_s0006012700 I 0.784
TRE_0001987301 Trichobilharzia regenti TRE_0001987301 I 0.784
ASIM_0001604001 Anisakis simplex ASIM_0001604001 I 0.784
TTRE_0000855901 Trichuris trichiura TTRE_0000855901 I 0.784
ACEP19585 Atta cephalotes ACEP19585 I 0.784
SMU15015494 Schmidtea mediterranea SMU15015494 I 0.775
GPUH_0001329001 Gongylonema pulchrum GPUH_0001329001 I 0.775
D915_03789 Fasciola hepatica D915_03789 I 0.775
ASU_13433 Ascaris suum ASU_13433 I 0.775
D917_09719 Trichinella nativa D917_09719 I 0.765
BTMF_0000404601 Brugia timori BTMF_0000404601 I 0.765
NEMVEDRAFT_v1g18576 Nematostella vectensis NEMVEDRAFT_v1g18576 I 0.765
Bm3575 Brugia malayi Bm3575 I 0.765
WUBG_02880 Wuchereria bancrofti WUBG_02880 I 0.765
Sjc_0030450 Schistosoma japonicum Sjc_0030450 I 0.765
EFV62078 Trichinella spiralis EFV62078 I 0.765
TCLT_0000917301 Thelazia callipaeda TCLT_0000917301 I 0.755
SMTD_0002197901 Schistosoma mattheei SMTD_0002197901 I 0.755
HelroG76435 Helobdella robusta HelroG76435 I 0.755
Smp_033950 Schistosoma mansoni Smp_033950 I 0.755
nDi.2.2.2.g01429 Dirofilaria immitis nDi.2.2.2.g01429 I 0.755
nLs.2.1.2.g01457 Litomosoides sigmodontis nLs.2.1.2.g01457 I 0.745
nOo.2.0.1.g00181 Onchocerca ochengi nOo.2.0.1.g00181 I 0.745
LOAG_08923 Loa loa LOAG_08923 I 0.745
WBGene00241622 Onchocerca volvulus WBGene00241622 I 0.745
SROB_0000384401 Schistosoma rodhaini SROB_0000384401 I 0.745
EEL_0000707501 Elaeophora elaphi EEL_0000707501 I 0.745
nAv.1.0.1.g00430 Acanthocheilonema viteae nAv.1.0.1.g00430 I 0.745
ENSLOCG00000012872 Lepisosteus oculatus ENSLOCG00000012872 I 0.735
Sakowv30001112m.g Saccoglossus kowalevskii Sakowv30001112m.g I 0.716
Aqu1.229767 Amphimedon queenslandica Aqu1.229767 I 0.716
tetur10g00380 Tetranychus urticae tetur10g00380 I 0.709
L893_g344 Steinernema glaseri L893_g344 I 0.706
L898_g17086 Steinernema monticolum L898_g17086 I 0.706