NFIA (Homo sapiens)
SMAD

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF03165 (MH1) IPR003619 ENSG00000162599 T324628_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
This gene encodes a member of the NF1 (nuclear factor 1) family of transcription factors. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
NFIA
M03480_2.00
Homo sapiens
YTGGCANNNTGCCAA

TTGGCANNNTGCCAR
SELEX
Jolma et al.(2013)
NFIA_1
(Direct) (Direct)
NFIA
M03481_2.00
Homo sapiens
NNTGCCAANN

NNTTGGCANN
SELEX
Jolma et al.(2013)
NFIA_2
(Direct) (Direct)
NFIA
M09379_2.00
Homo sapiens
YTGGCWNYNDGCCAD

HTGGCHNRNWGCCAR
Misc
Kulakovskiy et al.(2013)
NFIA_HUMAN.H11MO.0.C
(Direct) (Direct)
NFIA
M11282_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$NF1A_Q6_01
(Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
Nfia
M09383_2.00
Mus musculus
YTGGCWNYNDGCCAD

HTGGCHNRNWGCCAR
Misc
Kulakovskiy et al.(2013)
NFIA_MOUSE.H11MO.0.C
1.000 1.000
Nfia
M11291_2.00
Rattus norvegicus Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$NFIA_02
1.000 1.000
NFIB
M03479_2.00
Homo sapiens
YTGGCANNNTGCCAA

TTGGCANNNTGCCAR
SELEX
Jolma et al.(2013)
NFIB_1
0.934 0.934
NFIX
M03475_2.00
Homo sapiens
YTGGCNNNNTGCCAA

TTGGCANNNNGCCAR
SELEX
Jolma et al.(2013)
NFIX_1
0.934 0.934
NFIX
M03476_2.00
Homo sapiens
NYTGGCDNN

NNHGCCARN
SELEX
Jolma et al.(2013)
NFIX_2
0.934 0.934
NFIX
M03477_2.00
Homo sapiens
NYTGGCWNN

NNWGCCARN
SELEX
Jolma et al.(2013)
NFIX_3
0.934 0.934
NFIX
M03478_2.00
Homo sapiens
TTGGCANNNTGCCAR

YTGGCANNNTGCCAA
SELEX
Jolma et al.(2013)
NFIX_4
0.934 0.934
NFIB
M05747_2.00
Homo sapiens
NYTGGCNNNNYGCCARN

NYTGGCRNNNNGCCARN
SELEX
Yin et al.(2017)
NFIB_FL_HT-SELEX
0.934 0.934
NFIX
M05741_2.00
Homo sapiens
NHTGGCDNNNTGCCADN

NHTGGCANNNHGCCADN
SELEX
Yin et al.(2017)
NFIX_FL_HT-SELEX
0.934 0.934
Nfib
M09381_2.00
Mus musculus
BVWGCCARV

BYTGGCWBV
Misc
Kulakovskiy et al.(2013)
NFIB_MOUSE.H11MO.0.C
0.934 0.934
NFIB
M11280_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$NF1B_Q6_01
0.934 0.934
NFIB
M11281_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$NF1B_Q6
0.934 0.934
NFIB
M05748_2.00
Homo sapiens
NTTGGCDNNNTGCCARN

NYTGGCANNNHGCCAAN
SELEX
Yin et al.(2017)
NFIB_FL_Methyl-HT-SELEX
0.934 0.934
NFIX
M05742_2.00
Homo sapiens
NYTGGCDNNNTGCCARN

NYTGGCANNNHGCCARN
SELEX
Yin et al.(2017)
NFIX_FL_Methyl-HT-SELEX
0.934 0.934
Nfic
M09385_2.00
Mus musculus
NBYTGGCWN

NWGCCARVN
Misc
Kulakovskiy et al.(2013)
NFIC_MOUSE.H11MO.0.A
0.868 0.868
NFIC
M05745_2.00
Homo sapiens
NTTGGCNNNNTGCCARN

NYTGGCANNNNGCCAAN
SELEX
Yin et al.(2017)
NFIC_FL_HT-SELEX
0.857 0.857
NFIC
M08164_2.00
Homo sapiens
NNCTTGGCANN

NNTGCCAAGNN
ChIP-seq
Mathelier et al.(2014)
MA0161.2
0.857 0.857
NFIC
M09378_2.00
Homo sapiens
BYTGGMHBYNDKCCMRV

BYKGGMHNRVDKCCARV
Misc
Kulakovskiy et al.(2013)
NFIC_HUMAN.H11MO.0.A
0.857 0.857
NFIC
M09635_2.00
Homo sapiens
BYTGSCAV

BTGSCARV
Misc
Heinz et al.(2010)
LNCaP-NF1_Unpublished
0.857 0.857
NFIC
M09636_2.00
Homo sapiens
BYTGGCHNNNDGCCAR

YTGGCHNNNDGCCARV
Misc
Heinz et al.(2010)
LNCAP-NF1_Unpublished
0.857 0.857
NFIC
M11278_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$CTF1_01
0.857 0.857
NFIC
M11279_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$NF1C_Q6
0.857 0.857
NFIC
M05746_2.00
Homo sapiens
NYTGGCNNNNYGCCARN

NYTGGCRNNNNGCCARN
SELEX
Yin et al.(2017)
NFIC_FL_Methyl-HT-SELEX
0.857 0.857
NfI
M03968_2.00
Drosophila melanogaster
YTGGCDNNNHGCCAR

YTGGCDNNNHGCCAR
SELEX
Nitta et al.(2015)
NfI_1
0.780 0.780
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000360226 SMAD 68 172
ENSP00000360227 SMAD 68 172
ENSP00000360229 SMAD 68 172
ENSP00000360231 SMAD 113 217
ENSP00000360233 SMAD 91 195
ENSP00000384523 SMAD 68 172
ENSP00000384680 SMAD 60 164
ENSP00000419785 SMAD 68 172
ENSP00000473830 SMAD 1 76
ENSP00000474461 SMAD 21 125

Links

Other SMAD family TFs
Other Homo sapiens TFs

363 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
baz2a.L Xenopus laevis XB-GENE-965905 N 0.000
BAZ2A Sus scrofa ENSSSCG00000000403 N 0.000
ENSSHAG00000000118 Sarcophilus harrisii ENSSHAG00000000118 N 0.000
BAZ2A Sorex araneus ENSSARG00000009404 N 0.000
Baz2a Rattus norvegicus ENSRNOG00000053881 N 0.000
BAZ2A Pteropus vampyrus ENSPVAG00000007618 N 0.000
BAZ2A Pan troglodytes ENSPTRG00000005106 N 0.000
ENSPPYG00000004667 Pongo abelii ENSPPYG00000004667 N 0.000
BAZ2A Procavia capensis ENSPCAG00000010434 N 0.000
ENSPANG00000021120 Papio anubis ENSPANG00000021120 N 0.000
BAZ2A Ochotona princeps ENSOPRG00000001687 N 0.000
ENSSTOG00000013452 Ictidomys tridecemlineatus ENSSTOG00000013452 N 0.000
BAZ2A Tupaia belangeri ENSTBEG00000001463 N 0.000
BAZ2A Tursiops truncatus ENSTTRG00000002130 N 0.000
baz2a Xenopus tropicalis XB-GENE-965900 N 0.000
Pvit_00723 Pogona vitticeps Pvit_00723 N 0.000
Myotis_brandtii_BAZ2A_10002672 Myotis brandtii Myotis_brandtii_BAZ2A_10002672 N 0.000
ENSP00000368754 Macaca fascicularis ENSP00000368754 N 0.000
ENSBTAP00000038030-D1 Bos grunniens ENSBTAP00000038030-D1 N 0.000
Cmyd_10002714 Chelonia mydas Cmyd_10002714 N 0.000
Alligator_sinensis_CCG000760.1 Alligator sinensis Alligator_sinensis_CCG000760.1 N 0.000
Afo_R009805 Aptenodytes forsteri Afo_R009805 N 0.000
Aan_R000723 Calypte anna Aan_R000723 N 0.000
BAZ2A Vicugna pacos ENSVPAG00000004023 N 0.000
BAZ2A Otolemur garnettii ENSOGAG00000003537 N 0.000
BAZ2A Oryctolagus cuniculus ENSOCUG00000006079 N 0.000
BAZ2A Echinops telfairi ENSETEG00000010203 N 0.000
BAZ2A Equus caballus ENSECAG00000018243 N 0.000
BAZ2A Dasypus novemcinctus ENSDNOG00000011221 N 0.000
ENSCSAG00000005062 Chlorocebus sabaeus ENSCSAG00000005062 N 0.000
BAZ2A Cavia porcellus ENSCPOG00000006404 N 0.000
BAZ2A Callithrix jacchus ENSCJAG00000010774 N 0.000
BAZ2A Choloepus hoffmanni ENSCHOG00000007335 N 0.000
BAZ2A Canis familiaris ENSCAFG00000000135 N 0.000
BAZ2A Bos taurus ENSBTAG00000017840 N 0.000
ENSAMEG00000004115 Ailuropoda melanoleuca ENSAMEG00000004115 N 0.000
BAZ2A Felis catus ENSFCAG00000012029 N 0.000
BAZ2A Homo sapiens ENSG00000076108 N 0.000
BAZ2A Gorilla gorilla ENSGGOG00000011580 N 0.000
ENSOARG00000008407 Ovis aries ENSOARG00000008407 N 0.000
ENSNLEG00000017462 Nomascus leucogenys ENSNLEG00000017462 N 0.000
Baz2a Mus musculus ENSMUSG00000040054 N 0.000
ENSMPUG00000001495 Mustela putorius furo ENSMPUG00000001495 N 0.000
BAZ2A Macaca mulatta ENSMMUG00000019332 N 0.000
ENSMLUG00000000546 Myotis lucifugus ENSMLUG00000000546 N 0.000
ENSMEUG00000002868 Macropus eugenii ENSMEUG00000002868 N 0.000
ENSLOCG00000007281 Lepisosteus oculatus ENSLOCG00000007281 N 0.000
BAZ2A Loxodonta africana ENSLAFG00000008255 N 0.000
ENSLACG00000018672 Latimeria chalumnae ENSLACG00000018672 N 0.000
BAZ2A Anolis carolinensis ENSACAG00000016700 N 0.000