NEMVEDRAFT_v1g248037 (Nematostella vectensis)
SMAD

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF03165 (MH1) IPR003619 NEMVEDRAFT_v1g248037 T325165_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Smad4
M05889_2.00 		Mus musculus
KCYAGACR
YGTCTRGM		 SMiLE-seq
Isakova et al.(2017)
Smad4 		0.931 0.931
Med
M06447_2.00 		Drosophila melanogaster
KCGBCDKKSHVT
ABDSMMHGVCGM		 B1H
Zhu et al.(2011)
Med_FlyReg_FBgn0011655 		0.931 0.931
SMAD4
M09377_2.00 		Homo sapiens
DRGTGNSAGACWN
NWGTCTSNCACYH		 Misc
Kulakovskiy et al.(2013)
SMAD4_HUMAN.H11MO.0.B 		0.931 0.931
Smad4
M09382_2.00 		Mus musculus
DGWGNBAGVCWN
NWGBCTVNCWCH		 Misc
Kulakovskiy et al.(2013)
SMAD4_MOUSE.H11MO.0.A 		0.931 0.931
SMAD4
M09634_2.00 		Homo sapiens
NNNYGTCTGS
SCAGACRNNN		 Misc
Heinz et al.(2010)
ESC-SMAD4_GSE29422 		0.931 0.931
Med
M09693_2.00 		Drosophila melanogaster
YYBYVYCTGYY
RRCAGRBRVRR		 Misc
Kulakovskiy et al.(2009)
Med 		0.931 0.931
SMAD4
M11275_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD4_Q4 		0.931 0.931
SMAD4
M11276_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD4_Q6_01 		0.931 0.931
SMAD4
M11277_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD4_Q6 		0.931 0.931
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
EDO31382 SMAD 31 132

Links

Other SMAD family TFs
Other Nematostella vectensis TFs

215 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
L798_13939 Zootermopsis nevadensis L798_13939 I 0.941
SMAR013850 Strigamia maritima SMAR013850 I 0.941
TC010848 Tribolium castaneum TC010848 I 0.941
smad4a Danio rerio ENSDARG00000075226 I 0.941
ENSXMAG00000015245 Xiphophorus maculatus ENSXMAG00000015245 I 0.941
smad4a Oryzias latipes ENSORLG00000005020 I 0.941
ENSPFOG00000018987 Poecilia formosa ENSPFOG00000018987 I 0.941
ENSAMXG00000019219 Astyanax mexicanus ENSAMXG00000019219 I 0.941
PHUM002670 Pediculus humanus PHUM002670 I 0.941
LDEC015949 Leptinotarsa decemlineata LDEC015949 I 0.941
AAEL013896 Aedes aegypti AAEL013896 I 0.941
GF22974 Drosophila ananassae FBgn0099968 I 0.931
GA14643 Drosophila pseudoobscura FBgn0074670 I 0.931
MDOA012885 Musca domestica MDOA012885 I 0.931
Med Drosophila melanogaster FBgn0011655 D 0.931
GG11819 Drosophila erecta FBgn0104114 I 0.931
GI23400 Drosophila mojavensis FBgn0146126 I 0.931
GJ23092 Drosophila virilis FBgn0210194 I 0.931
CpipJ_CPIJ002563 Culex pipiens CpipJ_CPIJ002563 I 0.931
GM16436 Drosophila sechellia FBgn0171351 I 0.931
GL23637 Drosophila persimilis FBgn0161227 I 0.931
SMAD4 Vicugna pacos ENSVPAG00000006757 I 0.931
GH18642 Drosophila grimshawi FBgn0126109 I 0.931
SMAD4 Tupaia belangeri ENSTBEG00000014105 I 0.931
ENSPANG00000024703 Papio anubis ENSPANG00000024703 I 0.931
ENSPPYG00000009165 Pongo abelii ENSPPYG00000009165 I 0.931
PPAI002168 Phlebotomus papatasi PPAI002168 I 0.931
SMAD4 Ochotona princeps ENSOPRG00000013601 I 0.931
ENSONIG00000015035 Oreochromis niloticus ENSONIG00000015035 I 0.931
ENSPSIG00000014614 Pelodiscus sinensis ENSPSIG00000014614 I 0.931
SMAD4 Pan troglodytes ENSPTRG00000010028 I 0.931
ENSSTOG00000028580 Ictidomys tridecemlineatus ENSSTOG00000028580 I 0.931
GE10952 Drosophila yakuba FBgn0228782 I 0.931
SMAD4 Sus scrofa ENSSSCG00000004524 I 0.931
ENSSHAG00000010344 Sarcophilus harrisii ENSSHAG00000010344 I 0.931
Smad4 Rattus norvegicus ENSRNOG00000051965 I 0.931
ENSTSYG00000009792 Tarsius syrichta ENSTSYG00000009792 I 0.931
GB50071 Apis mellifera GB50071 I 0.931
Gfo_R011803 Geospiza fortis Gfo_R011803 I 0.931
Gfo_R016223 Geospiza fortis Gfo_R016223 I 0.931
ENSP00000381452 Macaca fascicularis ENSP00000381452 I 0.931
ENSP00000341551-D1 Bos grunniens ENSP00000341551-D1 I 0.931
Cmyd_10005540 Chelonia mydas Cmyd_10005540 I 0.931
Hsal_09633--XP_392838.3_APIME Harpegnathos saltator Hsal_09633--XP_392838.3_APIME I 0.931
Myotis_brandtii_Smad4_10005924 Myotis brandtii Myotis_brandtii_Smad4_10005924 I 0.931
AAH84196 Xenopus laevis AAH84196 I 0.931
CLEC002594 Cimex lectularius CLEC002594 I 0.931
e_gw.452.68.1 Branchiostoma floridae e_gw.452.68.1 I 0.931
Pvit_01119 Pogona vitticeps Pvit_01119 I 0.931
Ogr14199 Ophisaurus gracilis Ogr14199 I 0.931
Cflo_07183--XP_392838.3_APIME Camponotus floridanus Cflo_07183--XP_392838.3_APIME I 0.931
Brh_R010414 Buceros rhinoceros Brh_R010414 I 0.931
NV12984 Nasonia vitripennis NV12984 I 0.931
SMAD4 Otolemur garnettii ENSOGAG00000012081 I 0.931
smad4.1.L Xenopus laevis XB-GENE-865543 I 0.931
ISCW018468 Ixodes scapularis ISCW018468 I 0.931
HHAL000394-PA Halyomorpha halys HHAL000394-PA I 0.931
RPRC010188 Rhodnius prolixus RPRC010188 I 0.931
SINV15516 Solenopsis invicta SINV15516 I 0.931
Alligator_sinensis_CCG008910.1 Alligator sinensis Alligator_sinensis_CCG008910.1 I 0.931
LCUP007928 Lucilia cuprina LCUP007928 I 0.931
Afo_R008709 Aptenodytes forsteri Afo_R008709 I 0.931
YQE_06624 Dendroctonus ponderosae YQE_06624 I 0.931
smad4.1 Xenopus tropicalis XB-GENE-485691 I 0.931
LLOJ008806 Lutzomyia longipalpis LLOJ008806 I 0.931
GK11724 Drosophila willistoni FBgn0213735 I 0.931
SMAD4 Echinops telfairi ENSETEG00000007750 I 0.931
SMAD4 Equus caballus ENSECAG00000017857 I 0.931
Smad4 Dipodomys ordii ENSDORG00000009089 I 0.931
SMAD4 Dasypus novemcinctus ENSDNOG00000005063 I 0.931
SMAD4 Felis catus ENSFCAG00000005257 I 0.931
SMAD4 Homo sapiens ENSG00000141646 D 0.931
ENSGMOG00000005844 Gadus morhua ENSGMOG00000005844 I 0.931
SMAD4 Gorilla gorilla ENSGGOG00000013662 I 0.931
SMAD4 Bos taurus ENSBTAG00000006919 I 0.931
ENSCSAG00000018094 Chlorocebus sabaeus ENSCSAG00000018094 I 0.931
SMAD4 Cavia porcellus ENSCPOG00000006470 I 0.931
SMAD4 Oryctolagus cuniculus ENSOCUG00000003929 I 0.931
ENSAPLG00000003924 Anas platyrhynchos ENSAPLG00000003924 I 0.931
SMAD4 Canis familiaris ENSCAFG00000000164 I 0.931
ENSAMEG00000002899 Ailuropoda melanoleuca ENSAMEG00000002899 I 0.931
SMAD4 Choloepus hoffmanni ENSCHOG00000000860 I 0.931
SMAD4 Callithrix jacchus ENSCJAG00000001910 I 0.931
CPIJ002563 Culex quinquefasciatus CPIJ002563 I 0.931
SMAD4 Anolis carolinensis ENSACAG00000010186 I 0.931
SMAD4 Loxodonta africana ENSLAFG00000012595 I 0.931
smad4a Gasterosteus aculeatus ENSGACG00000007495 I 0.931
ENSMPUG00000008776 Mustela putorius furo ENSMPUG00000008776 I 0.931
SMAD4 Monodelphis domestica ENSMODG00000010995 I 0.931
SMAD4 Macaca mulatta ENSMMUG00000018334 I 0.931
SMAD4 Myotis lucifugus ENSMLUG00000013944 I 0.931
Smad4 Mus musculus ENSMUSG00000024515 D 0.931
ENSNLEG00000011859 Nomascus leucogenys ENSNLEG00000011859 I 0.931
ENSOANG00000030959 Ornithorhynchus anatinus ENSOANG00000030959 I 0.931
ENSOARG00000004662 Ovis aries ENSOARG00000004662 I 0.931
SMAD4 Ornithorhynchus anatinus ENSOANG00000008117 I 0.931
SMAD4 Danio rerio ENSDARG00000012649 I 0.922
HMEL002203 Heliconius melpomene HMEL002203 I 0.922
smad4.2.S Xenopus laevis XB-GENE-5995204 I 0.922
KGM_12572 Danaus plexippus KGM_12572 I 0.922
AGAP002902 Anopheles gambiae AGAP002902 I 0.922
BGIBMGA010110 Bombyx mori BGIBMGA010110 I 0.922
SMAD4 Oryzias latipes ENSORLG00000007703 I 0.922
DAPPUDRAFT_304115 Daphnia pulex DAPPUDRAFT_304115 I 0.922
ENSPFOG00000019807 Poecilia formosa ENSPFOG00000019807 I 0.922
Ogr06720 Ophisaurus gracilis Ogr06720 I 0.922
HHAL000393-PA Halyomorpha halys HHAL000393-PA I 0.922
smad4.2.L Xenopus laevis XB-GENE-6256010 I 0.922
MCINX014520 Melitaea cinxia MCINX014520 I 0.922
ASTEI00079 Anopheles stephensi ASTEI00079 I 0.922
SMAD4 Takifugu rubripes ENSTRUG00000014045 I 0.922
ACUA025512 Anopheles culicifacies ACUA025512 I 0.922
AMAM019778 Anopheles maculatus AMAM019778 I 0.922
ADIR002761 Anopheles dirus ADIR002761 I 0.922
AEPI002385 Anopheles epiroticus AEPI002385 I 0.922
AFUN009864 Anopheles funestus AFUN009864 I 0.922
AFAF011208 Anopheles farauti AFAF011208 I 0.922
SMAD4 Tetraodon nigroviridis ENSTNIG00000009050 I 0.922
ENSXMAG00000005051 Xiphophorus maculatus ENSXMAG00000005051 I 0.922
ACOM037505 Anopheles coluzzii ACOM037505 I 0.922
AQUA009305 Anopheles quadriannulatus AQUA009305 I 0.922
AATE010695 Anopheles atroparvus AATE010695 I 0.922
AARA004719 Anopheles arabiensis AARA004719 I 0.922
ACHR000067 Anopheles christyi ACHR000067 I 0.922
AMIN000723 Anopheles minimus AMIN000723 I 0.922
AMEM015931 Anopheles merus AMEM015931 I 0.922
ENSONIG00000014036 Oreochromis niloticus ENSONIG00000014036 I 0.912
ACYPI000365 Acyrthosiphon pisum ACYPI000365 I 0.912
ENSGACG00000016858 Gasterosteus aculeatus ENSGACG00000016858 I 0.912
ENSLACG00000007810 Latimeria chalumnae ENSLACG00000007810 I 0.912
BGLB014287 Biomphalaria glabrata BGLB014287 I 0.902
AALB009485 Anopheles albimanus AALB009485 I 0.902
ADAC007516 Anopheles darlingi ADAC007516 I 0.902
CapteG179368 Capitella teleta CapteG179368 I 0.902
ENSAMXG00000017275 Astyanax mexicanus ENSAMXG00000017275 I 0.902
ENSAMXG00000018339 Astyanax mexicanus ENSAMXG00000018339 I 0.902
si:dkey-222b8.1 Takifugu rubripes ENSTRUG00000004163 I 0.902
ENSGMOG00000013964 Gadus morhua ENSGMOG00000013964 I 0.902
si:dkey-222b8.1 Gasterosteus aculeatus ENSGACG00000000538 I 0.902
gb:cr929477 Tetraodon nigroviridis ENSTNIG00000003193 I 0.902
ENSMEUG00000001823 Macropus eugenii ENSMEUG00000001823 I 0.902
ENSONIG00000001557 Oreochromis niloticus ENSONIG00000001557 I 0.902
ENSONIG00000010360 Oreochromis niloticus ENSONIG00000010360 I 0.902
ENSPMAG00000008404 Petromyzon marinus ENSPMAG00000008404 I 0.902
si:dkey-222b8.1 Danio rerio ENSDARG00000045094 I 0.902
gb:cr929477 Takifugu rubripes ENSTRUG00000011769 I 0.902
ENSPMAG00000009414 Petromyzon marinus ENSPMAG00000009414 I 0.892
SPU_004287 Strongylocentrotus purpuratus SPU_004287 I 0.892
si:dkey-239n17.4 Danio rerio ENSDARG00000070428 I 0.892
ENSGMOG00000000297 Gadus morhua ENSGMOG00000000297 I 0.892
Ocbimv22032358m.g Octopus bimaculoides Ocbimv22032358m.g I 0.892
LotgiG131078 Lottia gigantea LotgiG131078 I 0.892
smad4 Ciona intestinalis ENSCING00000005559 I 0.882
si:dkey-222b8.1 Tetraodon nigroviridis ENSTNIG00000005007 I 0.882
ENSCSAVG00000006480 Ciona savignyi ENSCSAVG00000006480 I 0.882
ENSPFOG00000019867 Poecilia formosa ENSPFOG00000019867 I 0.882
fgenesh2_pg.scaffold_230000050 Branchiostoma floridae fgenesh2_pg.scaffold_230000050 I 0.882
tetur10g00400 Tetranychus urticae tetur10g00400 I 0.873
ACYPI003759 Acyrthosiphon pisum ACYPI003759 I 0.863
YQE_08737 Dendroctonus ponderosae YQE_08737 I 0.863
Alligator_sinensis_CCG001823.1 Alligator sinensis Alligator_sinensis_CCG001823.1 I 0.863
ENSGACG00000003171 Gasterosteus aculeatus ENSGACG00000003171 I 0.863
XP_002161797.1 Hydra magnipapillata XP_002161797.1 I 0.853
ACYPI008450 Acyrthosiphon pisum ACYPI008450 I 0.853
HelroG88197 Helobdella robusta HelroG88197 I 0.843
ACYPI005550 Acyrthosiphon pisum ACYPI005550 I 0.833
Aqu1.215834 Amphimedon queenslandica Aqu1.215834 I 0.833
Aqu1.215833 Amphimedon queenslandica Aqu1.215833 I 0.833
ML02191a Mnemiopsis leidyi ML02191a I 0.824
SPU_017971 Strongylocentrotus purpuratus SPU_017971 I 0.818
T265_11013 Opisthorchis viverrini T265_11013 I 0.814
ACEP19585 Atta cephalotes ACEP19585 I 0.814
TTRE_0000855901 Trichuris trichiura TTRE_0000855901 I 0.804
TMUE_s0006012700 Trichuris muris TMUE_s0006012700 I 0.804
TriadG30731 Trichoplax adhaerens TriadG30731 I 0.804
SMU15015494 Schmidtea mediterranea SMU15015494 I 0.794
D917_09719 Trichinella nativa D917_09719 I 0.794
GPUH_0001329001 Gongylonema pulchrum GPUH_0001329001 I 0.794
EFV62078 Trichinella spiralis EFV62078 I 0.794
Aan_R014474 Calypte anna Aan_R014474 I 0.793
BTMF_0000404601 Brugia timori BTMF_0000404601 I 0.784
ASIM_0001604001 Anisakis simplex ASIM_0001604001 I 0.784
Bm3575 Brugia malayi Bm3575 I 0.784
ECPE_0001832001 Echinostoma caproni ECPE_0001832001 I 0.784
HelroG76435 Helobdella robusta HelroG76435 I 0.784
ASU_13433 Ascaris suum ASU_13433 I 0.775
EEL_0000707501 Elaeophora elaphi EEL_0000707501 I 0.775
nAv.1.0.1.g00430 Acanthocheilonema viteae nAv.1.0.1.g00430 I 0.775
WUBG_02880 Wuchereria bancrofti WUBG_02880 I 0.775
nLs.2.1.2.g01457 Litomosoides sigmodontis nLs.2.1.2.g01457 I 0.775
nDi.2.2.2.g01429 Dirofilaria immitis nDi.2.2.2.g01429 I 0.775
D915_03789 Fasciola hepatica D915_03789 I 0.775
CGI_10000594 Crassostrea gigas CGI_10000594 I 0.768
nOo.2.0.1.g00181 Onchocerca ochengi nOo.2.0.1.g00181 I 0.765
TCLT_0000917301 Thelazia callipaeda TCLT_0000917301 I 0.765
LOAG_08923 Loa loa LOAG_08923 I 0.765
ENSLOCG00000012872 Lepisosteus oculatus ENSLOCG00000012872 I 0.765
WBGene00241622 Onchocerca volvulus WBGene00241622 I 0.765
Sjc_0030450 Schistosoma japonicum Sjc_0030450 I 0.755
TRE_0001987301 Trichobilharzia regenti TRE_0001987301 I 0.755
Aqu1.229767 Amphimedon queenslandica Aqu1.229767 I 0.745
SMTD_0002197901 Schistosoma mattheei SMTD_0002197901 I 0.735
Smp_033950 Schistosoma mansoni Smp_033950 I 0.735
tetur10g00380 Tetranychus urticae tetur10g00380 I 0.733
SROB_0000384401 Schistosoma rodhaini SROB_0000384401 I 0.725
SVUK_0000938201 Strongylus vulgaris SVUK_0000938201 I 0.716
NEMVEDRAFT_v1g18576 Nematostella vectensis NEMVEDRAFT_v1g18576 I 0.716
ANCCAN_20978 Ancylostoma caninum ANCCAN_20978 I 0.716
TELCIR_19676 Teladorsagia circumcincta TELCIR_19676 I 0.716
Sakowv30001112m.g Saccoglossus kowalevskii Sakowv30001112m.g I 0.716
OESDEN_03018 Oesophagostomum dentatum OESDEN_03018 I 0.716
L893_g15056 Steinernema glaseri L893_g15056 I 0.706
L893_g344 Steinernema glaseri L893_g344 I 0.706
HCOI00676200 Haemonchus contortus HCOI00676200 I 0.706
L889_g22387 Steinernema feltiae L889_g22387 I 0.703