|
HHAL002936-PA
(Halyomorpha halys)
SMAD
|
TF Information |
Pfam ID |
Interpro ID |
Gene ID |
CIS-BP ID |
Sequence source |
PF03165 (MH1) |
IPR003619 |
HHAL002936-PA |
T325395_2.00 |
Misc (2018-Jan-19) |
NCBI Gene Info:This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016] |
Directly determined binding motifs |
Name/Motif ID |
Species |
Forward |
Reverse |
Type/Study/Study ID |
SR Score |
DBD Identity |
No direct experiments |
|
|
|
|
|
Motifs from related TFs |
Name/Motif ID |
Species |
Forward |
Reverse |
Type/Study/Study ID |
SR Score |
DBD Identity |
NfI
M03968_2.00 |
Drosophila melanogaster |
YTGGCDNNNHGCCAR |
YTGGCDNNNHGCCAR |
SELEX
Nitta et al.(2015)
NfI_1
|
0.901
|
0.901
|
NFIC
M05745_2.00 |
Homo sapiens |
NTTGGCNNNNTGCCARN |
NYTGGCANNNNGCCAAN |
SELEX
Yin et al.(2017)
NFIC_FL_HT-SELEX
|
0.890
|
0.890
|
NFIC
M08164_2.00 |
Homo sapiens |
NNCTTGGCANN |
NNTGCCAAGNN |
ChIP-seq
Mathelier et al.(2014)
MA0161.2
|
0.890
|
0.890
|
NFIC
M09378_2.00 |
Homo sapiens |
BYTGGMHBYNDKCCMRV |
BYKGGMHNRVDKCCARV |
Misc
Kulakovskiy et al.(2013)
NFIC_HUMAN.H11MO.0.A
|
0.890
|
0.890
|
NFIC
M09635_2.00 |
Homo sapiens |
BYTGSCAV |
BTGSCARV |
Misc
Heinz et al.(2010)
LNCaP-NF1_Unpublished
|
0.890
|
0.890
|
NFIC
M09636_2.00 |
Homo sapiens |
BYTGGCHNNNDGCCAR |
YTGGCHNNNDGCCARV |
Misc
Heinz et al.(2010)
LNCAP-NF1_Unpublished
|
0.890
|
0.890
|
NFIC
M11278_2.00 |
Homo sapiens |
Transfac license required
|
Transfac license required
|
Transfac
Matys et al.(2006)
V$CTF1_01
|
0.890
|
0.890
|
NFIC
M11279_2.00 |
Homo sapiens |
Transfac license required
|
Transfac license required
|
Transfac
Matys et al.(2006)
V$NF1C_Q6
|
0.890
|
0.890
|
NFIC
M05746_2.00 |
Homo sapiens |
NYTGGCNNNNYGCCARN |
NYTGGCRNNNNGCCARN |
SELEX
Yin et al.(2017)
NFIC_FL_Methyl-HT-SELEX
|
0.890
|
0.890
|
Nfic
M09385_2.00 |
Mus musculus |
NBYTGGCWN |
NWGCCARVN |
Misc
Kulakovskiy et al.(2013)
NFIC_MOUSE.H11MO.0.A
|
0.868
|
0.868
|
NFIA
M03480_2.00 |
Homo sapiens |
YTGGCANNNTGCCAA |
TTGGCANNNTGCCAR |
SELEX
Jolma et al.(2013)
NFIA_1
|
0.813
|
0.813
|
NFIA
M03481_2.00 |
Homo sapiens |
NNTGCCAANN |
NNTTGGCANN |
SELEX
Jolma et al.(2013)
NFIA_2
|
0.813
|
0.813
|
NFIA
M09379_2.00 |
Homo sapiens |
YTGGCWNYNDGCCAD |
HTGGCHNRNWGCCAR |
Misc
Kulakovskiy et al.(2013)
NFIA_HUMAN.H11MO.0.C
|
0.813
|
0.813
|
Nfia
M09383_2.00 |
Mus musculus |
YTGGCWNYNDGCCAD |
HTGGCHNRNWGCCAR |
Misc
Kulakovskiy et al.(2013)
NFIA_MOUSE.H11MO.0.C
|
0.813
|
0.813
|
NFIA
M11282_2.00 |
Homo sapiens |
Transfac license required
|
Transfac license required
|
Transfac
Matys et al.(2006)
V$NF1A_Q6_01
|
0.813
|
0.813
|
Nfia
M11291_2.00 |
Rattus norvegicus |
Transfac license required
|
Transfac license required
|
Transfac
Matys et al.(2006)
V$NFIA_02
|
0.813
|
0.813
|
NFIX
M03475_2.00 |
Homo sapiens |
YTGGCNNNNTGCCAA |
TTGGCANNNNGCCAR |
SELEX
Jolma et al.(2013)
NFIX_1
|
0.791
|
0.791
|
NFIX
M03476_2.00 |
Homo sapiens |
NYTGGCDNN |
NNHGCCARN |
SELEX
Jolma et al.(2013)
NFIX_2
|
0.791
|
0.791
|
NFIX
M03477_2.00 |
Homo sapiens |
NYTGGCWNN |
NNWGCCARN |
SELEX
Jolma et al.(2013)
NFIX_3
|
0.791
|
0.791
|
NFIX
M03478_2.00 |
Homo sapiens |
TTGGCANNNTGCCAR |
YTGGCANNNTGCCAA |
SELEX
Jolma et al.(2013)
NFIX_4
|
0.791
|
0.791
|
NFIX
M05741_2.00 |
Homo sapiens |
NHTGGCDNNNTGCCADN |
NHTGGCANNNHGCCADN |
SELEX
Yin et al.(2017)
NFIX_FL_HT-SELEX
|
0.791
|
0.791
|
NFIX
M05742_2.00 |
Homo sapiens |
NYTGGCDNNNTGCCARN |
NYTGGCANNNHGCCARN |
SELEX
Yin et al.(2017)
NFIX_FL_Methyl-HT-SELEX
|
0.791
|
0.791
|
NFIB
M03479_2.00 |
Homo sapiens |
YTGGCANNNTGCCAA |
TTGGCANNNTGCCAR |
SELEX
Jolma et al.(2013)
NFIB_1
|
0.769
|
0.769
|
NFIB
M05747_2.00 |
Homo sapiens |
NYTGGCNNNNYGCCARN |
NYTGGCRNNNNGCCARN |
SELEX
Yin et al.(2017)
NFIB_FL_HT-SELEX
|
0.769
|
0.769
|
Nfib
M09381_2.00 |
Mus musculus |
BVWGCCARV |
BYTGGCWBV |
Misc
Kulakovskiy et al.(2013)
NFIB_MOUSE.H11MO.0.C
|
0.769
|
0.769
|
NFIB
M11280_2.00 |
Homo sapiens |
Transfac license required
|
Transfac license required
|
Transfac
Matys et al.(2006)
V$NF1B_Q6_01
|
0.769
|
0.769
|
NFIB
M11281_2.00 |
Homo sapiens |
Transfac license required
|
Transfac license required
|
Transfac
Matys et al.(2006)
V$NF1B_Q6
|
0.769
|
0.769
|
NFIB
M05748_2.00 |
Homo sapiens |
NTTGGCDNNNTGCCARN |
NYTGGCANNNHGCCAAN |
SELEX
Yin et al.(2017)
NFIB_FL_Methyl-HT-SELEX
|
0.769
|
0.769
|
For this family, TFs with SR scores > 0.700 will likely have a similar motif |