OFLC_0001565801 (Onchocerca flexuosa)
SMAD

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source
PF03165 (MH1) IPR003619 OFLC_0001565801 T325865_2.00 WormBase:ParaSite (2015-Oct-22)

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Mad
M06446_2.00 		Drosophila melanogaster
GYGHCGBCVS
SBGVCGDCRC		 B1H
Zhu et al.(2011)
Mad_FlyReg_FBgn0011648 		0.722 0.722
Mad
M08427_2.00 		Drosophila melanogaster
SNGRCGMSRVSRBNS
SNVYSBYSKCGYCNS		 ChIP-chip
Mathelier et al.(2014)
MA0535.1 		0.722 0.722
Mad
M09692_2.00 		Drosophila melanogaster
KCBGSHGKCGCSNC
GNSGCGMCDSCVGM		 Misc
Kulakovskiy et al.(2009)
Mad 		0.722 0.722
Mad
M11293_2.00 		Drosophila melanogaster Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
I$MAD_Q6 		0.722 0.722
SMAD5
M05743_2.00 		Homo sapiens
YGTCTAGACW
WGTCTAGACR		 SELEX
Yin et al.(2017)
SMAD5_eDBD_HT-SELEX 		0.704 0.704
Smad5
M11288_2.00 		Mus musculus Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD5_01 		0.704 0.704
SMAD5
M11271_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD5_02 		0.704 0.704
Smad5
M11292_2.00 		Rattus norvegicus Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD5_03 		0.704 0.704
SMAD5
M11272_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD5_Q5_01 		0.704 0.704
SMAD5
M11273_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD5_Q5 		0.704 0.704
SMAD9
M11274_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD8_01 		0.704 0.704
Smad9
M11290_2.00 		Rattus norvegicus Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD8_02 		0.704 0.704
Smad9
M11289_2.00 		Mus musculus Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SMAD8_03 		0.704 0.704
SMAD5
M05744_2.00 		Homo sapiens
CGTCTAGACR
YGTCTAGACG		 SELEX
Yin et al.(2017)
SMAD5_eDBD_Methyl-HT-SELEX 		0.704 0.704
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
OFLC_0001565801-mRNA-1 SMAD 27 83

Links

Other SMAD family TFs
Other Onchocerca flexuosa TFs

219 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
nDi.2.2.2.g04365 Dirofilaria immitis nDi.2.2.2.g04365 I 0.889
nAv.1.0.1.g00979 Acanthocheilonema viteae nAv.1.0.1.g00979 I 0.889
Bm5383 Brugia malayi Bm5383 I 0.889
WBGene00246233 Onchocerca volvulus WBGene00246233 I 0.889
WUBG_01190 Wuchereria bancrofti WUBG_01190 I 0.889
TCLT_0000734101 Thelazia callipaeda TCLT_0000734101 I 0.870
nLs.2.1.2.g04119 Litomosoides sigmodontis nLs.2.1.2.g04119 I 0.870
TCNE_0001440901 Toxocara canis TCNE_0001440901 I 0.870
ASU_08570 Ascaris suum ASU_08570 I 0.870
DME_0000409101 Dracunculus medinensis DME_0000409101 I 0.852
GPUH_0002149301 Gongylonema pulchrum GPUH_0002149301 I 0.833
GPUH_0002623401 Gongylonema pulchrum GPUH_0002623401 I 0.833
nOo.2.0.1.g11302 Onchocerca ochengi nOo.2.0.1.g11302 I 0.833
ALUE_0002104001 Ascaris lumbricoides ALUE_0002104001 I 0.815
PTRK_0001409600 Parastrongyloides trichosuri PTRK_0001409600 I 0.796
ASIM_0002076001 Anisakis simplex ASIM_0002076001 I 0.796
SMUV_0000762601 Syphacia muris SMUV_0000762601 I 0.796
SPAL_0000266700 Strongyloides papillosus SPAL_0000266700 I 0.796
SSTP_0000598700 Strongyloides stercoralis SSTP_0000598700 I 0.778
scaffold778-EXSNAP2012.5 Pristionchus exspectatus scaffold778-EXSNAP2012.5 N 0.778
SVE_1899900 Strongyloides venezuelensis SVE_1899900 I 0.778
PHUM612490 Pediculus humanus PHUM612490 I 0.759
L898_g8161 Steinernema monticolum L898_g8161 I 0.759
L889_g17000 Steinernema feltiae L889_g17000 I 0.759
L596_g25216 Steinernema carpocapsae L596_g25216 I 0.759
ENSLACG00000011178 Latimeria chalumnae ENSLACG00000011178 I 0.759
BTMF_0000942101 Brugia timori BTMF_0000942101 I 0.759
TTRE_0000645601 Trichuris trichiura TTRE_0000645601 I 0.759
D918_06928 Trichuris suis D918_06928 I 0.759
TMUE_s0173000400 Trichuris muris TMUE_s0173000400 I 0.759
HelroG186716 Helobdella robusta HelroG186716 I 0.759
TTAC_0000954401 Hydatigera taeniaeformis TTAC_0000954401 I 0.741
BXY_1645200 Bursaphelenchus xylophilus BXY_1645200 I 0.741
csin106589 Clonorchis sinensis csin106589 I 0.741
SMAR012602 Strigamia maritima SMAR012602 I 0.741
SPU_023107 Strongylocentrotus purpuratus SPU_023107 I 0.741
Sjc_0006780 Schistosoma japonicum Sjc_0006780 I 0.741
SPU_020722 Strongylocentrotus purpuratus SPU_020722 I 0.741
SROB_0000039301 Schistosoma rodhaini SROB_0000039301 I 0.741
DILT_0000355601 Diphyllobothrium latum DILT_0000355601 I 0.741
Smp_013060 Schistosoma mansoni Smp_013060 I 0.741
ISCW010869 Ixodes scapularis ISCW010869 I 0.741
D915_05666 Fasciola hepatica D915_05666 I 0.741
DAPPUDRAFT_300607 Daphnia pulex DAPPUDRAFT_300607 I 0.741
MCOS_0000603801 Mesocestoides corti MCOS_0000603801 I 0.741
maker-nMf.1.1.scaf04862-augustus-gene-0.4 Meloidogyne floridensis maker-nMf.1.1.scaf04862-augustus-gene-0.4 I 0.741
TsM_000781600 Taenia solium TsM_000781600 I 0.741
SCUD_0000553301 Schistosoma curassoni SCUD_0000553301 I 0.741
SMTD_0001194901 Schistosoma mattheei SMTD_0001194901 I 0.741
SMRZ_0000889701 Schistosoma margrebowiei SMRZ_0000889701 I 0.741
HNAJ_0000781101 Hymenolepis nana HNAJ_0000781101 I 0.741
T265_01150 Opisthorchis viverrini T265_01150 I 0.741
ECPE_0001803101 Echinostoma caproni ECPE_0001803101 I 0.741
ECANG7_02712 Echinococcus canadensis ECANG7_02712 I 0.741
HmN_000160100 Hymenolepis microstoma HmN_000160100 I 0.741
TASK_0000610701 Taenia asiatica TASK_0000610701 I 0.741
EmuJ_001018300 Echinococcus multilocularis EmuJ_001018300 I 0.741
HDID_0000986701 Hymenolepis diminuta HDID_0000986701 I 0.741
AAK02019 Xenopus laevis AAK02019 I 0.722
Tal_R004657 Tyto alba Tal_R004657 I 0.722
estExt_fgenesh2_pg.C_20279 Branchiostoma floridae estExt_fgenesh2_pg.C_20279 I 0.722
Pvit_04328 Pogona vitticeps Pvit_04328 I 0.722
estExt_fgenesh2_pm.C_1880004 Branchiostoma floridae estExt_fgenesh2_pm.C_1880004 I 0.722
Hsal_07345--XP_392819.2_APIME Harpegnathos saltator Hsal_07345--XP_392819.2_APIME I 0.722
Sakowv30001252m.g Saccoglossus kowalevskii Sakowv30001252m.g I 0.722
AAL86772 Xenopus laevis AAL86772 I 0.722
Alligator_sinensis_CCG012577.1 Alligator sinensis Alligator_sinensis_CCG012577.1 I 0.722
NV13248 Nasonia vitripennis NV13248 I 0.722
CpipJ_CPIJ000420 Culex pipiens CpipJ_CPIJ000420 I 0.722
PHUM612590 Pediculus humanus PHUM612590 I 0.722
Aan_R005227 Calypte anna Aan_R005227 I 0.722
Afo_R003117 Aptenodytes forsteri Afo_R003117 I 0.722
Cflo_02382--XP_392819.2_APIME Camponotus floridanus Cflo_02382--XP_392819.2_APIME I 0.722
Brh_R009512 Buceros rhinoceros Brh_R009512 I 0.722
Gfo_R005758 Geospiza fortis Gfo_R005758 I 0.722
AMEC005585 Anopheles melas AMEC005585 I 0.722
AMEM010864 Anopheles merus AMEM010864 I 0.722
AMIN001006 Anopheles minimus AMIN001006 I 0.722
AMAM023956 Anopheles maculatus AMAM023956 I 0.722
AFUN010580 Anopheles funestus AFUN010580 I 0.722
AFAF000844 Anopheles farauti AFAF000844 I 0.722
AQUA000239 Anopheles quadriannulatus AQUA000239 I 0.722
ASTEI05192 Anopheles stephensi ASTEI05192 I 0.722
EVEC_0000230001 Enterobius vermicularis EVEC_0000230001 I 0.722
LotgiG104873 Lottia gigantea LotgiG104873 I 0.722
PPAI007902 Phlebotomus papatasi PPAI007902 I 0.722
LLOJ009024 Lutzomyia longipalpis LLOJ009024 I 0.722
AEPI001857 Anopheles epiroticus AEPI001857 I 0.722
ADIR010877 Anopheles dirus ADIR010877 I 0.722
smad9.S Xenopus laevis XB-GENE-865114 I 0.722
Minc07882 Meloidogyne incognita Minc07882 I 0.722
smad9 Xenopus tropicalis XB-GENE-484686 I 0.722
LDEC003904 Leptinotarsa decemlineata LDEC003904 I 0.722
AAL86774 Xenopus laevis AAL86774 I 0.722
AALB000402 Anopheles albimanus AALB000402 I 0.722
AARA011030 Anopheles arabiensis AARA011030 I 0.722
ACUA022001 Anopheles culicifacies ACUA022001 I 0.722
ACUA017601 Anopheles culicifacies ACUA017601 I 0.722
ACHR005633 Anopheles christyi ACHR005633 I 0.722
AATE020501 Anopheles atroparvus AATE020501 I 0.722
AAL86773 Xenopus laevis AAL86773 I 0.722
SINV11024 Solenopsis invicta SINV11024 I 0.722
ENSCSAVG00000002875 Ciona savignyi ENSCSAVG00000002875 I 0.722
ENSMEUG00000007556 Macropus eugenii ENSMEUG00000007556 I 0.722
smad9 Danio rerio ENSDARG00000021938 I 0.722
smad5 Danio rerio ENSDARG00000037238 I 0.722
ENSGMOG00000005788 Gadus morhua ENSGMOG00000005788 I 0.722
ENSCING00000022875 Ciona intestinalis ENSCING00000022875 I 0.722
ENSGMOG00000012301 Gadus morhua ENSGMOG00000012301 I 0.722
ENSAMXG00000010992 Astyanax mexicanus ENSAMXG00000010992 I 0.722
smad5 Tetraodon nigroviridis ENSTNIG00000003701 I 0.722
ENSAPLG00000009135 Anas platyrhynchos ENSAPLG00000009135 I 0.722
SMAD9 Monodelphis domestica ENSMODG00000010017 I 0.722
ENSSHAG00000001186 Sarcophilus harrisii ENSSHAG00000001186 I 0.722
ENSPSIG00000002483 Pelodiscus sinensis ENSPSIG00000002483 I 0.722
ENSPMAG00000009833 Petromyzon marinus ENSPMAG00000009833 I 0.722
ENSONIG00000015791 Oreochromis niloticus ENSONIG00000015791 I 0.722
ENSFALG00000008280 Ficedula albicollis ENSFALG00000008280 I 0.722
ENSONIG00000012614 Oreochromis niloticus ENSONIG00000012614 I 0.722
SMAD9 Ornithorhynchus anatinus ENSOANG00000015497 I 0.722
L798_03803 Zootermopsis nevadensis L798_03803 I 0.722
smad9 Gasterosteus aculeatus ENSGACG00000020562 I 0.722
smad9 Oryzias latipes ENSORLG00000003956 I 0.722
ENSPFOG00000015910 Poecilia formosa ENSPFOG00000015910 I 0.722
ENSPFOG00000015984 Poecilia formosa ENSPFOG00000015984 I 0.722
ENSPFOG00000005752 Poecilia formosa ENSPFOG00000005752 I 0.722
SMAD9 Gallus gallus ENSGALG00000017050 I 0.722
smad5 Oryzias latipes ENSORLG00000009395 I 0.722
smad5 Gasterosteus aculeatus ENSGACG00000018718 I 0.722
smad5 Takifugu rubripes ENSTRUG00000001329 I 0.722
GD22774 Drosophila simulans FBgn0194168 I 0.722
GJ19553 Drosophila virilis FBgn0206695 I 0.722
AGAP008551 Anopheles gambiae AGAP008551 I 0.722
ENSLOCG00000011514 Lepisosteus oculatus ENSLOCG00000011514 I 0.722
GM18164 Drosophila sechellia FBgn0173071 I 0.722
SMAD9 Meleagris gallopavo ENSMGAG00000015060 I 0.722
GK18268 Drosophila willistoni FBgn0220267 I 0.722
HMEL009295 Heliconius melpomene HMEL009295 I 0.722
ADAC002355 Anopheles darlingi ADAC002355 I 0.722
GB44177 Apis mellifera GB44177 I 0.722
GA28973 Drosophila pseudoobscura FBgn0250331 I 0.722
GE14935 Drosophila yakuba FBgn0232525 I 0.722
KGM_04785 Danaus plexippus KGM_04785 I 0.722
GL26531 Drosophila persimilis FBgn0164113 I 0.722
CPIJ000420 Culex quinquefasciatus CPIJ000420 I 0.722
ENSXMAG00000016280 Xiphophorus maculatus ENSXMAG00000016280 I 0.722
SMAD9 Anolis carolinensis ENSACAG00000004463 I 0.722
ENSXMAG00000008595 Xiphophorus maculatus ENSXMAG00000008595 I 0.722
AAEL005513 Aedes aegypti AAEL005513 I 0.722
Mad Drosophila melanogaster FBgn0011648 D 0.722
CGI_10014747 Crassostrea gigas CGI_10014747 I 0.722
GH10284 Drosophila grimshawi FBgn0117765 I 0.722
GG24457 Drosophila erecta FBgn0116589 I 0.722
GF20577 Drosophila ananassae FBgn0097583 I 0.722
GI17981 Drosophila mojavensis FBgn0140721 I 0.722
ENSLOCG00000008478 Lepisosteus oculatus ENSLOCG00000008478 I 0.722
HPLM_0000851001 Haemonchus placei HPLM_0000851001 N 0.704
HCOI01110700 Haemonchus contortus HCOI01110700 N 0.704
SMAD9 Loxodonta africana ENSLAFG00000002903 I 0.704
ENSLACG00000007324 Latimeria chalumnae ENSLACG00000007324 I 0.704
SMAD9 Gorilla gorilla ENSGGOG00000001017 I 0.704
ENSCSAG00000017872 Chlorocebus sabaeus ENSCSAG00000017872 I 0.704
ENSAMEG00000014442 Ailuropoda melanoleuca ENSAMEG00000014442 I 0.704
SMAD9 Bos taurus ENSBTAG00000007589 I 0.704
SVUK_0001208601 Strongylus vulgaris SVUK_0001208601 N 0.704
BGIBMGA010481 Bombyx mori BGIBMGA010481 I 0.704
ACYPI010124 Acyrthosiphon pisum ACYPI010124 I 0.704
TELCIR_10810 Teladorsagia circumcincta TELCIR_10810 N 0.704
SMAD9 Canis familiaris ENSCAFG00000006162 I 0.704
Smad9 Dipodomys ordii ENSDORG00000002526 I 0.704
SMAD9 Felis catus ENSFCAG00000003813 I 0.704
SMAD5 Homo sapiens ENSG00000113658 D 0.704
SMAD9 Echinops telfairi ENSETEG00000020236 I 0.704
SMAD9 Equus caballus ENSECAG00000012534 I 0.704
Smad5 Dipodomys ordii ENSDORG00000004533 I 0.704
NECAME_03891 Necator americanus NECAME_03891 N 0.704
SMAD9 Homo sapiens ENSG00000120693 D 0.704
BGLB010651 Biomphalaria glabrata BGLB010651 I 0.704
SMAD9 Sus scrofa ENSSSCG00000009357 I 0.704
ENSSTOG00000007103 Ictidomys tridecemlineatus ENSSTOG00000007103 I 0.704
SMAD9 Tupaia belangeri ENSTBEG00000011491 I 0.704
ENSTSYG00000005021 Tarsius syrichta ENSTSYG00000005021 I 0.704
CLEC006591 Cimex lectularius CLEC006591 I 0.704
LCUP000453 Lucilia cuprina LCUP000453 I 0.704
Smad9 Rattus norvegicus ENSRNOG00000000091 D 0.704
LOC103691556 Rattus norvegicus ENSRNOG00000058416 I 0.704
SMAD9 Sorex araneus ENSSARG00000011878 I 0.704
SMAD9 Tursiops truncatus ENSTTRG00000007903 I 0.704
Ogr17529 Ophisaurus gracilis Ogr17529 I 0.704
NV15769 Nasonia vitripennis NV15769 I 0.704
NEMVEDRAFT_v1g228395 Nematostella vectensis NEMVEDRAFT_v1g228395 I 0.704
MESCA005689 Megaselia scalaris MESCA005689 I 0.704
TC014921 Tribolium castaneum TC014921 I 0.704
tetur04g09040 Tetranychus urticae tetur04g09040 I 0.704
Myotis_brandtii_SMAD9_10010468 Myotis brandtii Myotis_brandtii_SMAD9_10010468 I 0.704
ENSP00000382216 Macaca fascicularis ENSP00000382216 I 0.704
ENSBTAP00000029021-D3 Bos grunniens ENSBTAP00000029021-D3 I 0.704
SMAD9 Pteropus vampyrus ENSPVAG00000013871 I 0.704
SMAD9 Pan troglodytes ENSPTRG00000005788 I 0.704
ENSNLEG00000001639 Nomascus leucogenys ENSNLEG00000001639 I 0.704
ANCCAN_05759 Ancylostoma caninum ANCCAN_05759 N 0.704
SMAD5 Ornithorhynchus anatinus ENSOANG00000009906 I 0.704
ACAC_0000906701 Angiostrongylus cantonensis ACAC_0000906701 N 0.704
Smad9 Mus musculus ENSMUSG00000027796 D 0.704
ENSMPUG00000001838 Mustela putorius furo ENSMPUG00000001838 I 0.704
SMAD9 Microcebus murinus ENSMICG00000003343 I 0.704
SMAD9 Myotis lucifugus ENSMLUG00000006399 I 0.704
SMAD9 Macaca mulatta ENSMMUG00000009914 I 0.704
MDOA015236 Musca domestica MDOA015236 I 0.704
MDOA012257 Musca domestica MDOA012257 I 0.704
ENSPANG00000014460 Papio anubis ENSPANG00000014460 I 0.704
SMAD9 Procavia capensis ENSPCAG00000002604 I 0.704
ENSPPYG00000005285 Pongo abelii ENSPPYG00000005285 I 0.704
SMAD5 Ochotona princeps ENSOPRG00000010102 I 0.704
SMAD9 Ochotona princeps ENSOPRG00000004923 I 0.704
ENSOARG00000010293 Ovis aries ENSOARG00000010293 I 0.704
SMAD9 Oryctolagus cuniculus ENSOCUG00000007453 I 0.704
SMAD9 Otolemur garnettii ENSOGAG00000002742 I 0.704
DICVIV_05604 Dictyocaulus viviparus DICVIV_05604 N 0.704