LEF1 (Echinops telfairi)
Sox

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00505 (HMG_box) IPR000910 ENSETEG00000018357 T327999_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
Lef1
M00200_2.00
Mus musculus
NSWTCAAAVN

NBTTTGAWSN
PBM
Badis et al.(2009)
Lef1_3504
0.672 0.942
LEF1
M03511_2.00
Homo sapiens
NRAGATCAAAGRVWW

WWBYCTTTGATCTYN
SELEX
Jolma et al.(2013)
LEF1_1
0.672 0.942
LEF1
M05771_2.00
Homo sapiens
NSATCAAAS

STTTGATSN
SELEX
Yin et al.(2017)
LEF1_eDBD_HT-SELEX_1
0.672 0.942
LEF1
M05772_2.00
Homo sapiens
WCATCGRGRCGCTGW

WCAGCGYCYCGATGW
SELEX
Yin et al.(2017)
LEF1_eDBD_HT-SELEX_2
0.672 0.942
LEF1
M05775_2.00
Homo sapiens
ASATCAAAG

CTTTGATST
SELEX
Yin et al.(2017)
LEF1_FL_HT-SELEX_1
0.672 0.942
LEF1
M05776_2.00
Homo sapiens
ACATCGRGRCGCTGW

WCAGCGYCYCGATGT
SELEX
Yin et al.(2017)
LEF1_FL_HT-SELEX_2
0.672 0.942
LEF1
M05895_2.00
Homo sapiens
WTCAAAGNNN

NNNCTTTGAW
SMiLE-seq
Isakova et al.(2017)
LEF1
0.672 0.942
LEF1
M09392_2.00
Homo sapiens
BSYTTTSWNNTBYH

DRVANNWSAAARSV
Misc
Kulakovskiy et al.(2013)
LEF1_HUMAN.H11MO.0.A
0.672 0.942
Lef1
M09402_2.00
Mus musculus
BSYTTTSWNNTBYH

DRVANNWSAAARSV
Misc
Kulakovskiy et al.(2013)
LEF1_MOUSE.H11MO.0.B
0.672 0.942
LEF1
M11311_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$LEF1_Q2_01
0.672 0.942
LEF1
M11312_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$LEF1_Q3
0.672 0.942
LEF1
M11313_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$LEF1_Q4
0.672 0.942
LEF1
M11314_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$LEF1_Q5_01
0.672 0.942
LEF1
M11315_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$LEF1_Q5
0.672 0.942
LEF1
M05773_2.00
Homo sapiens
ASATCAAAG

CTTTGATST
SELEX
Yin et al.(2017)
LEF1_eDBD_Methyl-HT-SELEX_1
0.672 0.942
LEF1
M05774_2.00
Homo sapiens
WCATCGRGGCGCTGW

WCAGCGCCYCGATGW
SELEX
Yin et al.(2017)
LEF1_eDBD_Methyl-HT-SELEX_2
0.672 0.942
LEF1
M05777_2.00
Homo sapiens
ASATCAAAG

CTTTGATST
SELEX
Yin et al.(2017)
LEF1_FL_Methyl-HT-SELEX_1
0.672 0.942
LEF1
M05778_2.00
Homo sapiens
ACATCGRGRCGCTGW

WCAGCGYCYCGATGT
SELEX
Yin et al.(2017)
LEF1_FL_Methyl-HT-SELEX_2
0.672 0.942
Tcf7l2
M00198_2.00
Mus musculus
NSWTCAAAVN

NBTTTGAWSN
PBM
Badis et al.(2009)
Tcf7l2_3461
0.672 0.928
Tcf7l2
M02646_2.00
Mus musculus
SATCAAAGN

NCTTTGATS
SELEX
Hallikas et al.(2006)
Tcf4
0.672 0.928
TCF7L2
M08167_2.00
Homo sapiens
NVASWTCAAAGVVN

NBBCTTTGAWSTBN
ChIP-seq
Mathelier et al.(2014)
MA0523.1
0.672 0.928
TCF7L2
M09393_2.00
Homo sapiens
DGCAGSTGKS

SMCASCTGCH
Misc
Kulakovskiy et al.(2013)
ITF2_HUMAN.H11MO.0.C
0.672 0.928
TCF7L2
M09394_2.00
Homo sapiens
VVASWTCAAAGVV

BBCTTTGAWSTBB
Misc
Kulakovskiy et al.(2013)
TF7L2_HUMAN.H11MO.0.A
0.672 0.928
Tcf7l2
M09401_2.00
Mus musculus
VVASWTCAAAGVV

BBCTTTGAWSTBB
Misc
Kulakovskiy et al.(2013)
TF7L2_MOUSE.H11MO.0.A
0.672 0.928
TCF7L2
M09638_2.00
Homo sapiens
CCTTTGAWST

ASWTCAAAGG
Misc
Heinz et al.(2010)
K562-TCF7L2_GSE29196
0.672 0.928
TCF7L2
M11316_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$TCF4_Q5_01
0.672 0.928
TCF7L2
M11317_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$TCF4_Q5_02
0.672 0.928
TCF7L2
M11318_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$TCF4_Q5
0.672 0.928
TCF7L2
M11319_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$TCF7L2_06
0.672 0.928
Tcf7l1
M00207_2.00
Mus musculus
NNNNWWDN

NHWWNNNN
PBM
Badis et al.(2009)
Tcf3_3787
0.672 0.870
TCF7L1
M03512_2.00
Homo sapiens
AAAGATCAAAGG

CCTTTGATCTTT
SELEX
Jolma et al.(2013)
TCF7L1_1
0.672 0.870
TCF7L1
M05779_2.00
Homo sapiens
RSATCAAAG

CTTTGATSY
SELEX
Yin et al.(2017)
TCF7L1_eDBD_HT-SELEX_1
0.672 0.870
TCF7L1
M05780_2.00
Homo sapiens
ACATCGRGRCGCTGW

WCAGCGYCYCGATGT
SELEX
Yin et al.(2017)
TCF7L1_eDBD_HT-SELEX_2
0.672 0.870
TCF7L1
M09395_2.00
Homo sapiens
NBBCTTTGAWSTB

VASWTCAAAGVVN
Misc
Kulakovskiy et al.(2013)
TF7L1_HUMAN.H11MO.0.B
0.672 0.870
Tcf7l1
M09406_2.00
Mus musculus
BBCTTTGAWST

ASWTCAAAGVV
Misc
Kulakovskiy et al.(2013)
TF7L1_MOUSE.H11MO.0.A
0.672 0.870
Tcf7l1
M09407_2.00
Mus musculus
NDGCAGSTGBB

VVCASCTGCHN
Misc
Kulakovskiy et al.(2013)
TFE2_MOUSE.H11MO.0.A
0.672 0.870
TCF7L1
M11320_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$TCF3_01
0.672 0.870
TCF7L1
M11321_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$TCF3_Q6_01
0.672 0.870
TCF7L1
M11322_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$TCF3_Q6
0.672 0.870
TCF7L1
M05781_2.00
Homo sapiens
CTTTGATSY

RSATCAAAG
SELEX
Yin et al.(2017)
TCF7L1_eDBD_Methyl-HT-SELEX_1
0.672 0.870
TCF7L1
M05782_2.00
Homo sapiens
ACATCGRGRCGCTGW

WCAGCGYCYCGATGT
SELEX
Yin et al.(2017)
TCF7L1_eDBD_Methyl-HT-SELEX_2
0.672 0.870
pan
M06451_2.00
Drosophila melanogaster
DWYCAAAD

HTTTGRWH
B1H
Zhu et al.(2011)
pan_FlyReg_FBgn0085432
0.651 0.855
pan
M08428_2.00
Drosophila melanogaster
WHNAAAVRNRSCGM

KCGSYNYBTTTNDW
ChIP-chip
Mathelier et al.(2014)
MA0237.2
0.651 0.855
pan
M11337_2.00
Drosophila melanogaster
AAGATCAAAGG

CCTTTGATCTT
Transfac
Matys et al.(2006)
I$TCF_1
0.651 0.855
pan
M11338_2.00
Drosophila melanogaster Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
I$TCF_Q6
0.651 0.855
Tcf7
M00193_2.00
Mus musculus
HNHNNNNNN

NNNNNNDND
PBM
Badis et al.(2009)
Tcf7_0950
0.647 0.913
Tcf7
M03532_2.00
Mus musculus
AAASATCAAAGV

BCTTTGATSTTT
SELEX
Jolma et al.(2013)
Tcf7_1
0.647 0.913
TCF7
M05755_2.00
Homo sapiens
DSATCAAWS

SWTTGATSH
SELEX
Yin et al.(2017)
TCF7_eDBD_HT-SELEX_1
0.647 0.913
TCF7
M05756_2.00
Homo sapiens
WCWKCGYCYCGWTGW

WCAWCGRGRCGMWGW
SELEX
Yin et al.(2017)
TCF7_eDBD_HT-SELEX_2
0.647 0.913
TCF7
M05890_2.00
Homo sapiens
NNASATCAAASNN

NNSTTTGATSTNN
SMiLE-seq
Isakova et al.(2017)
TCF7
0.647 0.913
TCF7
M09386_2.00
Homo sapiens
NBBCTTTSAWSTBNBN

NVNVASWTSAAAGVVN
Misc
Kulakovskiy et al.(2013)
TCF7_HUMAN.H11MO.0.A
0.647 0.913
Tcf7
M09400_2.00
Mus musculus
VVRVADSAAARVVVNV

BNBBBYTTTSHTBYBB
Misc
Kulakovskiy et al.(2013)
TCF7_MOUSE.H11MO.0.A
0.647 0.913
TCF7
M11294_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$TCF1_Q5_01
0.647 0.913
TCF7
M11295_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$TCF1_Q5
0.647 0.913
TCF7
M05757_2.00
Homo sapiens
RSATCAAAS

STTTGATSY
SELEX
Yin et al.(2017)
TCF7_eDBD_Methyl-HT-SELEX_1
0.647 0.913
TCF7
M05758_2.00
Homo sapiens
WCAWCGRGRCGMWGW

WCWKCGYCYCGWTGW
SELEX
Yin et al.(2017)
TCF7_eDBD_Methyl-HT-SELEX_2
0.647 0.913
pop-1
M00712_2.00
Caenorhabditis elegans
NNHDWVNNNN

NNNNBWHDNN
PBM
Narasimhan et al.(2015)
pTH9135
0.446 0.507
For this family, TFs with SR scores > 0.415 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSETEP00000014920 Sox 286 354

Links

Other Sox family TFs
Other Echinops telfairi TFs

483 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
ACRE_025820 Acremonium chrysogenum ACRE_025820 N 0.000
CFIO01_00502 Colletotrichum fioriniae CFIO01_00502 I 0.000
CGGC5_12972 Colletotrichum gloeosporioides CGGC5_12972 I 0.000
CH063_04960 Colletotrichum higginsianum CH063_04960 I 0.000
clr-2 Neurospora crassa NCU08042 D 0.000
CSUB01_07131 Colletotrichum sublineola CSUB01_07131 I 0.000
CTHT_0033840 Chaetomium thermophilum CTHT_0033840 I 0.000
e_gw1.3.2553.1 Cryphonectria parasitica e_gw1.3.2553.1 I 0.000
F503_04469 Ophiostoma piceae uamh F503_04469 I 0.000
FFUJ_09725 Fusarium fujikuroi FFUJ_09725 N 0.000
fgenesh3_pm.C_scaffold_3000122 Neurospora discreta fgenesh3_pm.C_scaffold_3000122 I 0.000
FGRRES_12282 Fusarium graminearum FGRRES_12282 N 0.000
FOXG_11357 Fusarium oxysporum FOXG_11357 N 0.000
FVEG_10459 Fusarium verticillioides FVEG_10459 N 0.000
GGTG_08810 Gaeumannomyces graminis GGTG_08810 I 0.000
GLRG_08292 Colletotrichum graminicola GLRG_08292 I 0.000
HMPREF1624_07333 Sporothrix schenckii HMPREF1624_07333 I 0.000
MAPG_04988 Magnaporthe poae MAPG_04988 I 0.000
MGG_01833 Magnaporthe oryzae MGG_01833 I 0.000
NEUTE1DRAFT_99711 Neurospora tetrasperma NEUTE1DRAFT_99711 I 0.000
PFICI_05693 Pestalotiopsis fici PFICI_05693 I 0.000
PODANS_6_1990 Podospora anserina PODANS_6_1990 I 0.000
S40285_05006 Stachybotrys chlorohalonata S40285_05006 I 0.000
S40285_08994 Stachybotrys chlorohalonata S40285_08994 I 0.000
S40288_04438 Stachybotrys chartarum S40288_04438 I 0.000
SMAC_03793 Sordaria macrospora SMAC_03793 I 0.000
THITE_2128774 Thielavia terrestris THITE_2128774 I 0.000
VDAG_00390 Verticillium dahliae VDAG_00390 I 0.000