Bbx (Mus musculus)
Sox

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00505 (HMG_box) IPR000910 ENSMUSG00000022641 T328495_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Acts upstream of or within bone development. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in nucleus. Is expressed in several structures, including central nervous system; dorsal root ganglion; early conceptus; genitourinary system; and sensory organ. Orthologous to human BBX (BBX high mobility group box domain containing). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Bbx
M00196_2.00		 Mus musculus
TTCATTGA
TCAATGAA		 PBM
Badis et al.(2009)
Bbx_3753		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
BBX
M05763_2.00 		Homo sapiens
TGAWCDNYGWTCA
TGAWCRNHGWTCA		 SELEX
Yin et al.(2017)
BBX_eDBD_HT-SELEX 		0.708 0.986
BBX
M05764_2.00 		Homo sapiens
TGAACDNYGTTCA
TGAACRNHGTTCA		 SELEX
Yin et al.(2017)
BBX_eDBD_Methyl-HT-SELEX 		0.708 0.986
bbx
M03975_2.00 		Drosophila melanogaster
NAACAATDNCATTGTTN
NAACAATGNHATTGTTN		 SELEX
Nitta et al.(2015)
bbx_1 		0.486 0.594
Cic
M00195_2.00 		Mus musculus
NNTGCTGABN
NVTCAGCANN		 PBM
Badis et al.(2009)
Cic_3454 		0.434 0.580
For this family, TFs with SR scores > 0.415 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M00196_2.00 Sox 17 85

DNA Binding Domains

Protein ID Domain From To Sequence
ENSMUSP00000086821 Sox 80 148
ENSMUSP00000086826 Sox 80 148
ENSMUSP00000110121 Sox 80 148
ENSMUSP00000110132 Sox 80 148
ENSMUSP00000119238 Sox 80 148

Links

Other Sox family TFs
Other Mus musculus TFs

240 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
Bbx Rattus norvegicus ENSRNOG00000001971 I 0.741
bbx Takifugu rubripes ENSTRUG00000003077 I 0.735
BBX Ornithorhynchus anatinus ENSOANG00000007497 I 0.708
ENSNLEG00000003524 Nomascus leucogenys ENSNLEG00000003524 I 0.708
ENSOARG00000018829 Ovis aries ENSOARG00000018829 I 0.708
BBX Ochotona princeps ENSOPRG00000017013 I 0.708
BBX Otolemur garnettii ENSOGAG00000008056 I 0.708
BBX Oryctolagus cuniculus ENSOCUG00000001686 I 0.708
ENSMPUG00000009907 Mustela putorius furo ENSMPUG00000009907 I 0.708
BBX Monodelphis domestica ENSMODG00000001748 I 0.708
BBX Felis catus ENSFCAG00000007296 I 0.708
BBX Echinops telfairi ENSETEG00000005122 I 0.708
BBX Erinaceus europaeus ENSEEUG00000014092 I 0.708
BBX Equus caballus ENSECAG00000023413 I 0.708
BBX Homo sapiens ENSG00000114439 D 0.708
BBX Gorilla gorilla ENSGGOG00000028441 I 0.708
BBX Macaca mulatta ENSMMUG00000008787 I 0.708
BBX Meleagris gallopavo ENSMGAG00000014384 I 0.708
ENSLACG00000001134 Latimeria chalumnae ENSLACG00000001134 I 0.708
ENSPANG00000018335 Papio anubis ENSPANG00000018335 I 0.708
ENSPPYG00000013578 Pongo abelii ENSPPYG00000013578 I 0.708
Cmyd_10015225 Chelonia mydas Cmyd_10015225 I 0.708
Alligator_sinensis_CCG019960.1 Alligator sinensis Alligator_sinensis_CCG019960.1 I 0.708
Afo_R006638 Aptenodytes forsteri Afo_R006638 I 0.708
ENSBTAP00000009058-D1 Bos grunniens ENSBTAP00000009058-D1 I 0.708
ENSMMUP00000011518 Macaca fascicularis ENSMMUP00000011518 I 0.708
XP_002932333 Xenopus tropicalis XP_002932333 I 0.708
bbx.L Xenopus laevis XB-GENE-981431 I 0.708
Tal_R013114 Tyto alba Tal_R013114 I 0.708
Aan_R014485 Calypte anna Aan_R014485 I 0.708
BBX Vicugna pacos ENSVPAG00000007818 I 0.708
BBX Pan troglodytes ENSPTRG00000015187 I 0.708
ENSPSIG00000015872 Pelodiscus sinensis ENSPSIG00000015872 I 0.708
Bbx Dipodomys ordii ENSDORG00000008169 I 0.708
BBX Pteropus vampyrus ENSPVAG00000010534 I 0.708
ENSSHAG00000003009 Sarcophilus harrisii ENSSHAG00000003009 I 0.708
ENSTSYG00000000857 Tarsius syrichta ENSTSYG00000000857 I 0.708
bbx Tetraodon nigroviridis ENSTNIG00000008596 I 0.708
BBX Sus scrofa ENSSSCG00000011943 I 0.708
BBX Procavia capensis ENSPCAG00000013443 I 0.708
BBX Tursiops truncatus ENSTTRG00000013182 I 0.708
BBX Callithrix jacchus ENSCJAG00000004843 I 0.708
BBX Cavia porcellus ENSCPOG00000003575 I 0.708
ENSCSAG00000006313 Chlorocebus sabaeus ENSCSAG00000006313 I 0.708
bbx Danio rerio ENSDARG00000012699 I 0.708
BBX Canis familiaris ENSCAFG00000009867 I 0.708
ENSAMEG00000002574 Ailuropoda melanoleuca ENSAMEG00000002574 I 0.708
ENSAPLG00000005336 Anas platyrhynchos ENSAPLG00000005336 I 0.708
BBX Dasypus novemcinctus ENSDNOG00000013923 I 0.708
BBX Bos taurus ENSBTAG00000006893 I 0.708
Gfo_R002593 Geospiza fortis Gfo_R002593 I 0.705
BBX Anolis carolinensis ENSACAG00000006532 I 0.705
ENSTGUG00000013611 Taeniopygia guttata ENSTGUG00000013611 I 0.705
Pvit_02469 Pogona vitticeps Pvit_02469 I 0.705
Ogr11041 Ophisaurus gracilis Ogr11041 I 0.705
ENSFALG00000006478 Ficedula albicollis ENSFALG00000006478 I 0.705
Brh_R008020 Buceros rhinoceros Brh_R008020 I 0.705
BBX Myotis lucifugus ENSMLUG00000007351 I 0.703
Myotis_brandtii_BBX_10016000 Myotis brandtii Myotis_brandtii_BBX_10016000 I 0.703
ENSAMXG00000017656 Astyanax mexicanus ENSAMXG00000017656 I 0.701
ENSXMAG00000009457 Xiphophorus maculatus ENSXMAG00000009457 I 0.701
BBX Loxodonta africana ENSLAFG00000006362 I 0.701
bbx Oryzias latipes ENSORLG00000005486 I 0.701
ENSGMOG00000015829 Gadus morhua ENSGMOG00000015829 I 0.701
bbx Gasterosteus aculeatus ENSGACG00000020111 I 0.701
ENSPFOG00000000813 Poecilia formosa ENSPFOG00000000813 I 0.701
ENSONIG00000004775 Oreochromis niloticus ENSONIG00000004775 I 0.699
Sakowv30039572m.g Saccoglossus kowalevskii Sakowv30039572m.g I 0.642
BGLB009093 Biomphalaria glabrata BGLB009093 I 0.623
ENSLOCG00000005165 Lepisosteus oculatus ENSLOCG00000005165 I 0.606
CapteG223458 Capitella teleta CapteG223458 I 0.590
LotgiG89909 Lottia gigantea LotgiG89909 I 0.590
CGI_10018417 Crassostrea gigas CGI_10018417 I 0.590
CapteG39110 Capitella teleta CapteG39110 I 0.590
ENSSSCG00000025539 Sus scrofa ENSSSCG00000025539 I 0.565
CpipJ_CPIJ005582 Culex pipiens CpipJ_CPIJ005582 I 0.541
AAEL011161 Aedes aegypti AAEL011161 I 0.541
CPIJ005582 Culex quinquefasciatus CPIJ005582 I 0.541
Ocbimv22001036m.g Octopus bimaculoides Ocbimv22001036m.g I 0.541
ISCW010061 Ixodes scapularis ISCW010061 I 0.525
HMEL012996 Heliconius melpomene HMEL012996 I 0.524
BGIBMGA008274 Bombyx mori BGIBMGA008274 I 0.524
LDEC000948 Leptinotarsa decemlineata LDEC000948 I 0.516
YQE_06837 Dendroctonus ponderosae YQE_06837 I 0.516
L798_02329 Zootermopsis nevadensis L798_02329 I 0.513
tetur23g01950 Tetranychus urticae tetur23g01950 I 0.506
ASTEI11145 Anopheles stephensi ASTEI11145 I 0.505
ASTEI00827 Anopheles stephensi ASTEI00827 I 0.505
SINV12425 Solenopsis invicta SINV12425 I 0.504
GB48450 Apis mellifera GB48450 I 0.504
Cflo_04908--XP_624175.2_APIME Camponotus floridanus Cflo_04908--XP_624175.2_APIME I 0.504
Hsal_01854--XP_624175.2_APIME Harpegnathos saltator Hsal_01854--XP_624175.2_APIME I 0.504
PAXRUDRAFT_130978 Paxillus rubicundulus PAXRUDRAFT_130978 I 0.495
SCLCIDRAFT_120630 Scleroderma citrinum SCLCIDRAFT_120630 I 0.495
CY34DRAFT_798812 Suillus luteus CY34DRAFT_798812 I 0.495
TC007499 Tribolium castaneum TC007499 I 0.489
MDOA012813 Musca domestica MDOA012813 I 0.486
GA16961 Drosophila pseudoobscura FBgn0076975 I 0.486
GK25081 Drosophila willistoni FBgn0227040 I 0.486
GI21541 Drosophila mojavensis FBgn0144271 I 0.486
GG19727 Drosophila erecta FBgn0111928 I 0.486
GF20922 Drosophila ananassae FBgn0097927 I 0.486
GJ16014 Drosophila virilis FBgn0203199 I 0.486
GE17925 Drosophila yakuba FBgn0235361 I 0.486
bbx Drosophila melanogaster FBgn0024251 D 0.486
GM23082 Drosophila sechellia FBgn0177950 I 0.486
LCUP006498 Lucilia cuprina LCUP006498 I 0.479
ECPE_0001539401 Echinostoma caproni ECPE_0001539401 I 0.477
CBG00068 Caenorhabditis briggsae CBG00068 I 0.473
AMAM016153 Anopheles maculatus AMAM016153 I 0.461
PISMIDRAFT_61363 Pisolithus microcarpus PISMIDRAFT_61363 I 0.460
M404DRAFT_998162 Pisolithus tinctorius M404DRAFT_998162 I 0.460
KGM_16790 Danaus plexippus KGM_16790 I 0.455
TVAG_010230 Trichomonas vaginalis TVAG_010230 I 0.452
SMAR012744 Strigamia maritima SMAR012744 I 0.450
D915_09544 Fasciola hepatica D915_09544 I 0.449
csin104163 Clonorchis sinensis csin104163 I 0.441
T265_01499 Opisthorchis viverrini T265_01499 I 0.441
ACYPI004663 Acyrthosiphon pisum ACYPI004663 I 0.441
PHUM230960 Pediculus humanus PHUM230960 I 0.439
SBAD_0000026401 Soboliphyme baturini SBAD_0000026401 I 0.438
ACEP13490 Atta cephalotes ACEP13490 I 0.436
AMIN000258 Anopheles minimus AMIN000258 I 0.436
ACUA015009 Anopheles culicifacies ACUA015009 I 0.434
ADIR003322 Anopheles dirus ADIR003322 I 0.434
Myotis_brandtii_Cic_10007129 Myotis brandtii Myotis_brandtii_Cic_10007129 I 0.434
CIC Gorilla gorilla ENSGGOG00000000192 I 0.434
Hsal_08911--XP_624175.2_APIME Harpegnathos saltator Hsal_08911--XP_624175.2_APIME I 0.434
ENSCPOG00000004391 Cavia porcellus ENSCPOG00000004391 I 0.434
ENSP00000160740-D1 Bos grunniens ENSP00000160740-D1 I 0.434
Cflo_01544--XP_624175.2_APIME Camponotus floridanus Cflo_01544--XP_624175.2_APIME I 0.434
ENSMEUG00000016625 Macropus eugenii ENSMEUG00000016625 I 0.434
ADAC008993 Anopheles darlingi ADAC008993 I 0.434
Alligator_sinensis_CCG005631.1 Alligator sinensis Alligator_sinensis_CCG005631.1 I 0.434
ENSLACG00000002764 Latimeria chalumnae ENSLACG00000002764 I 0.434
Cmyd_10001800 Chelonia mydas Cmyd_10001800 I 0.434
ENSP00000160740 Macaca fascicularis ENSP00000160740 I 0.434
Ogr10275 Ophisaurus gracilis Ogr10275 I 0.434
ACEP18843 Atta cephalotes ACEP18843 I 0.434
ENSGMOG00000005167 Gadus morhua ENSGMOG00000005167 I 0.434
CIC Homo sapiens ENSG00000079432 I 0.434
CIC Equus caballus ENSECAG00000011342 I 0.434
AEPI005675 Anopheles epiroticus AEPI005675 I 0.434
CIC Dasypus novemcinctus ENSDNOG00000047657 I 0.434
CLEC003268 Cimex lectularius CLEC003268 I 0.434
ASTEI00261 Anopheles stephensi ASTEI00261 I 0.434
cic Xenopus tropicalis XB-GENE-6467430 I 0.434
AARA001217 Anopheles arabiensis AARA001217 I 0.434
AALB003439 Anopheles albimanus AALB003439 I 0.434
CpipJ_CPIJ012202 Culex pipiens CpipJ_CPIJ012202 I 0.434
AQUA008168 Anopheles quadriannulatus AQUA008168 I 0.434
Sakowv30042695m.g Saccoglossus kowalevskii Sakowv30042695m.g I 0.434
AFAF009600 Anopheles farauti AFAF009600 I 0.434
ENSFCAG00000012737 Felis catus ENSFCAG00000012737 I 0.434
AMIN003810 Anopheles minimus AMIN003810 I 0.434
Pvit_02876 Pogona vitticeps Pvit_02876 I 0.434
ACHR006446 Anopheles christyi ACHR006446 I 0.434
AGAP013411 Anopheles gambiae AGAP013411 I 0.434
gw.448.64.1 Branchiostoma floridae gw.448.64.1 I 0.434
AMEM005678 Anopheles merus AMEM005678 I 0.434
Ocbimv22037932m.g Octopus bimaculoides Ocbimv22037932m.g I 0.434
CIC Echinops telfairi ENSETEG00000017271 I 0.434
gw.46.292.1 Branchiostoma floridae gw.46.292.1 I 0.434
cicb Gasterosteus aculeatus ENSGACG00000009452 I 0.434
CIC Canis familiaris ENSCAFG00000004858 I 0.434
ENSPPYG00000010041 Pongo abelii ENSPPYG00000010041 I 0.434
AMAM017484 Anopheles maculatus AMAM017484 I 0.434
BGIBMGA010263 Bombyx mori BGIBMGA010263 I 0.434
CIC Tursiops truncatus ENSTTRG00000013873 I 0.434
ENSPFOG00000016231 Poecilia formosa ENSPFOG00000016231 I 0.434
ENSPFOG00000000116 Poecilia formosa ENSPFOG00000000116 I 0.434
ENSONIG00000013108 Oreochromis niloticus ENSONIG00000013108 I 0.434
cicb Oryzias latipes ENSORLG00000013259 I 0.434
AMEC010127 Anopheles melas AMEC010127 I 0.434
ENSPANG00000009039 Papio anubis ENSPANG00000009039 I 0.434
CPIJ012202 Culex quinquefasciatus CPIJ012202 I 0.434
CIC Pan troglodytes ENSPTRG00000011051 I 0.434
CIC Tupaia belangeri ENSTBEG00000009044 I 0.434
ENSSTOG00000000852 Ictidomys tridecemlineatus ENSSTOG00000000852 I 0.434
Cic Rattus norvegicus ENSRNOG00000056118 I 0.434
CIC Sus scrofa ENSSSCG00000003030 I 0.434
CGI_10015746 Crassostrea gigas CGI_10015746 I 0.434
CIC Tetraodon nigroviridis ENSTNIG00000003521 I 0.434
CIC Takifugu rubripes ENSTRUG00000007193 I 0.434
CIC Pteropus vampyrus ENSPVAG00000016806 I 0.434
CapteG39126 Capitella teleta CapteG39126 I 0.434
CIC Callithrix jacchus ENSCJAG00000012847 I 0.434
GB43462 Apis mellifera GB43462 I 0.434
TC004697 Tribolium castaneum TC004697 I 0.434
SPU_025292 Strongylocentrotus purpuratus SPU_025292 I 0.434
LLOJ007756 Lutzomyia longipalpis LLOJ007756 I 0.434
SMAR009315 Strigamia maritima SMAR009315 I 0.434
ENSMPUG00000007557 Mustela putorius furo ENSMPUG00000007557 I 0.434
ENSMMUG00000012174 Macaca mulatta ENSMMUG00000012174 I 0.434
ENSMICG00000015176 Microcebus murinus ENSMICG00000015176 I 0.434
ENSMLUG00000016650 Myotis lucifugus ENSMLUG00000016650 I 0.434
AFUN006011 Anopheles funestus AFUN006011 I 0.434
Cic Mus musculus ENSMUSG00000005442 D 0.434
ENSBTAG00000019785 Bos taurus ENSBTAG00000019785 I 0.434
ENSAMXG00000018358 Astyanax mexicanus ENSAMXG00000018358 I 0.434
Cic Dipodomys ordii ENSDORG00000008822 I 0.434
ENSOCUG00000006458 Oryctolagus cuniculus ENSOCUG00000006458 I 0.434
KGM_16941 Danaus plexippus KGM_16941 I 0.434
MCINX015089 Melitaea cinxia MCINX015089 I 0.434
NV10910 Nasonia vitripennis NV10910 I 0.434
ENSNLEG00000010614 Nomascus leucogenys ENSNLEG00000010614 I 0.434
PHUM079880 Pediculus humanus PHUM079880 I 0.434
ENSOARG00000007985 Ovis aries ENSOARG00000007985 I 0.434
CIC Otolemur garnettii ENSOGAG00000003964 I 0.434
AATE006341 Anopheles atroparvus AATE006341 I 0.431
BGLB001462 Biomphalaria glabrata BGLB001462 I 0.428
D918_06270 Trichuris suis D918_06270 I 0.428
TMUE_s0223001200 Trichuris muris TMUE_s0223001200 I 0.428
D917_02434 Trichinella nativa D917_02434 I 0.428
TTRE_0000098801 Trichuris trichiura TTRE_0000098801 I 0.428
L798_08623 Zootermopsis nevadensis L798_08623 I 0.428
HHAL000065-PA Halyomorpha halys HHAL000065-PA I 0.428
RPRC001090 Rhodnius prolixus RPRC001090 I 0.428
cica Oryzias latipes ENSORLG00000007091 I 0.428
CRE24068 Caenorhabditis remanei CRE24068 I 0.428
AFAF016820 Anopheles farauti AFAF016820 I 0.428
CIC Procavia capensis ENSPCAG00000017001 I 0.428
AFUN003674 Anopheles funestus AFUN003674 I 0.426
tetur21g00740 Tetranychus urticae tetur21g00740 I 0.426
YQE_03282 Dendroctonus ponderosae YQE_03282 I 0.426
cica Danio rerio ENSDARG00000071150 I 0.426
AAEL004381 Aedes aegypti AAEL004381 I 0.426
ENSAMXG00000014362 Astyanax mexicanus ENSAMXG00000014362 I 0.426
TVAG_344020 Trichomonas vaginalis TVAG_344020 I 0.425
scaffold4-EXSNAP2012.129 Pristionchus exspectatus scaffold4-EXSNAP2012.129 I 0.421
ENSONIG00000004979 Oreochromis niloticus ENSONIG00000004979 I 0.420
PAAG_02636 Paracoccidioides sp lutzii PAAG_02636 I 0.417
SCUD_0001673101 Schistosoma curassoni SCUD_0001673101 I 0.416
B_00914 Schistosoma haematobium B_00914 I 0.416
ADIR003385 Anopheles dirus ADIR003385 I 0.416
Sjc_0093980 Schistosoma japonicum Sjc_0093980 I 0.416
SPU_023037 Strongylocentrotus purpuratus SPU_023037 I 0.416
GALMADRAFT_340474 Galerina marginata GALMADRAFT_340474 I 0.416
CGI_10003963 Crassostrea gigas CGI_10003963 I 0.416