polybromo (Drosophila melanogaster)
Sox

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00505 (HMG_box) IPR000910 FBgn0039227 T329520_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable chromatin binding activity. Involved in chorion-containing eggshell formation; chromatin remodeling; and negative regulation of transcription by RNA polymerase II. Part of brahma complex. Is expressed in several structures, including embryonic brain; embryonic/larval midgut; extended germ band embryo; and larval ventral nerve cord. Human ortholog(s) of this gene implicated in extrahepatic bile duct adenocarcinoma; lung non-small cell carcinoma; lung small cell carcinoma; and renal cell carcinoma. Orthologous to human PBRM1 (polybromo 1). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No TFs with similar DNA binding domains

DNA Binding Domains

Protein ID Domain From To Sequence
FBpp0084115 Sox 1316 1383

Links

Other Sox family TFs
Other Drosophila melanogaster TFs

Invalid Input OrderBy

65 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action