hmg-1.2 (Caenorhabditis elegans)
Sox

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00505 (HMG_box) IPR000910 WBGene00001972 T333268_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Enables transcription cis-regulatory region binding activity. Involved in several processes, including gonad development; positive regulation of transcription by RNA polymerase II; and vulval development. Located in nucleus. Is expressed in several structures, including anal depressor muscle; intestine; nervous system; pharynx; and reproductive system. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis; congestive heart failure; and syndromic microphthalmia 13. Orthologous to several human genes including HMGB3 (high mobility group box 3). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No TFs with similar DNA binding domains

DNA Binding Domains

Protein ID Domain From To Sequence
F47D12.4a.1 Sox 47 113
F47D12.4a.1 Sox 135 203
F47D12.4a.2 Sox 47 113
F47D12.4a.2 Sox 135 203
F47D12.4b Sox 46 112
F47D12.4b Sox 134 202
F47D12.4c.1 Sox 47 115
F47D12.4c.1 Sox 133 201
F47D12.4c.2 Sox 47 115
F47D12.4c.2 Sox 133 201

Links

Other Sox family TFs
Other Caenorhabditis elegans TFs

153 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
CJA09678 Caenorhabditis japonica CJA09678 N 0.735
CBN17977 Caenorhabditis brenneri CBN17977 N 0.733
CBG17468 Caenorhabditis briggsae CBG17468 N 0.732
CRE02943 Caenorhabditis remanei CRE02943 N 0.732
CJA42049 Caenorhabditis japonica CJA42049 N 0.704
NBR_0000911001 Nippostrongylus brasiliensis NBR_0000911001 N 0.696
ACOC_0000768601 Angiostrongylus costaricensis ACOC_0000768601 N 0.696
NECAME_09126 Necator americanus NECAME_09126 N 0.696
HCOI00860100 Haemonchus contortus HCOI00860100 N 0.696
TELCIR_07111 Teladorsagia circumcincta TELCIR_07111 N 0.696
Hba_13817 Heterorhabditis bacteriophora Hba_13817 N 0.691
SMUV_0000232601 Syphacia muris SMUV_0000232601 N 0.678
nAv.1.0.1.g02101 Acanthocheilonema viteae nAv.1.0.1.g02101 N 0.674
TCLT_0000879501 Thelazia callipaeda TCLT_0000879501 N 0.674
nDi.2.2.2.g04979 Dirofilaria immitis nDi.2.2.2.g04979 N 0.674
PEQ_0000150901 Parascaris equorum PEQ_0000150901 N 0.674
ASU_03902 Ascaris suum ASU_03902 N 0.674
EEL_0000068601 Elaeophora elaphi EEL_0000068601 N 0.674
LOAG_04936 Loa loa LOAG_04936 N 0.674
L596_g22130 Steinernema carpocapsae L596_g22130 N 0.674
TCNE_0000567001 Toxocara canis TCNE_0000567001 N 0.674
L892_g17551 Steinernema scapterisci L892_g17551 N 0.674
WBGene00245261 Onchocerca volvulus WBGene00245261 N 0.674
EVEC_0000577301 Enterobius vermicularis EVEC_0000577301 N 0.674
Bm4180 Brugia malayi Bm4180 N 0.674
L893_g5947 Steinernema glaseri L893_g5947 N 0.671
L889_g13533 Steinernema feltiae L889_g13533 N 0.669
TTRE_0000338301 Trichuris trichiura TTRE_0000338301 N 0.661
D918_07195 Trichuris suis D918_07195 N 0.661
DME_0001055201 Dracunculus medinensis DME_0001055201 N 0.658
PTRK_0000986200 Parastrongyloides trichosuri PTRK_0000986200 N 0.652
Ppa-hmg-1.2 Pristionchus pacificus PPA02361 N 0.652
nRc.2.0.1.g43473 Romanomermis culicivorax nRc.2.0.1.g43473 N 0.652
scaffold580-EXSNAP2012.5 Pristionchus exspectatus scaffold580-EXSNAP2012.5 N 0.652
SSTP_0000371800 Strongyloides stercoralis SSTP_0000371800 N 0.652
SPAL_0001030300 Strongyloides papillosus SPAL_0001030300 N 0.652
SVE_0494300 Strongyloides venezuelensis SVE_0494300 N 0.652
ANCCAN_10156 Ancylostoma caninum ANCCAN_10156 N 0.645
TMUE_s0235000800 Trichuris muris TMUE_s0235000800 N 0.645
ASIM_0000048401 Anisakis simplex ASIM_0000048401 N 0.640
D917_08189 Trichinella nativa D917_08189 N 0.634
SBAD_0000405201 Soboliphyme baturini SBAD_0000405201 N 0.633
WUBG_12099 Wuchereria bancrofti WUBG_12099 N 0.623
ACAC_0001052301 Angiostrongylus cantonensis ACAC_0001052301 N 0.620
ANCCEY_10333 Ancylostoma ceylanicum ANCCEY_10333 N 0.610
EFV57410 Trichinella spiralis EFV57410 N 0.608
D917_01254 Trichinella nativa D917_01254 N 0.608
genemark-nMf.1.1.scaf06964-processed-gene-0.3 Meloidogyne floridensis genemark-nMf.1.1.scaf06964-processed-gene-0.3 N 0.605
augustus_masked-nMf.1.1.scaf01778-processed-gene-0.2 Meloidogyne floridensis augustus_masked-nMf.1.1.scaf01778-processed-gene-0.2 N 0.605
EFV53345 Trichinella spiralis EFV53345 N 0.596
RSKR_0000605700 Rhabditophanes kr3021 RSKR_0000605700 N 0.594
nLs.2.1.2.g00300 Litomosoides sigmodontis nLs.2.1.2.g00300 N 0.584
BXY_1555400 Bursaphelenchus xylophilus BXY_1555400 N 0.572
TELCIR_06008 Teladorsagia circumcincta TELCIR_06008 N 0.564
GPUH_0001544201 Gongylonema pulchrum GPUH_0001544201 N 0.563
MhA1_Contig113.frz3.gene9 Meloidogyne hapla MhA1_Contig113.frz3.gene9 N 0.550
Minc03268 Meloidogyne incognita Minc03268 N 0.550
Minc08988 Meloidogyne incognita Minc08988 N 0.550
fgenesh2_pm.scaffold_24000033 Branchiostoma floridae fgenesh2_pm.scaffold_24000033 N 0.515
Minc01077 Meloidogyne incognita Minc01077 N 0.496
tetur02g08260 Tetranychus urticae tetur02g08260 N 0.473
tetur02g08340 Tetranychus urticae tetur02g08340 N 0.470
ISCW017350 Ixodes scapularis ISCW017350 N 0.469
MCOS_0000526101 Mesocestoides corti MCOS_0000526101 N 0.462
EmuJ_001049000 Echinococcus multilocularis EmuJ_001049000 N 0.462
TsM_000115400 Taenia solium TsM_000115400 N 0.462
CapteG158220 Capitella teleta CapteG158220 N 0.461
ACYPI007949 Acyrthosiphon pisum ACYPI007949 N 0.456
Sakowv30042012m.g Saccoglossus kowalevskii Sakowv30042012m.g N 0.449
SMAR013695 Strigamia maritima SMAR013695 N 0.447
CGI_10023724 Crassostrea gigas CGI_10023724 N 0.447
NV15664 Nasonia vitripennis NV15664 N 0.443
ECANG7_02036 Echinococcus canadensis ECANG7_02036 N 0.442
TTAC_0000225801 Hydatigera taeniaeformis TTAC_0000225801 N 0.442
PXEA_0000566701 Protopolystoma xenopodis PXEA_0000566701 N 0.441
HelroG157878 Helobdella robusta HelroG157878 N 0.440
DAPPUDRAFT_232871 Daphnia pulex DAPPUDRAFT_232871 N 0.439
PXEA_0002175501 Protopolystoma xenopodis PXEA_0002175501 N 0.437
SMU15016767 Schmidtea mediterranea SMU15016767 N 0.436
SPU_005572 Strongylocentrotus purpuratus SPU_005572 N 0.434
HmN_000466000 Hymenolepis microstoma HmN_000466000 N 0.434
HDID_0000237901 Hymenolepis diminuta HDID_0000237901 N 0.434
HNAJ_0001249801 Hymenolepis nana HNAJ_0001249801 N 0.434
AEPI002924 Anopheles epiroticus AEPI002924 N 0.433
T265_12733 Opisthorchis viverrini T265_12733 N 0.433
SMU15027649 Schmidtea mediterranea SMU15027649 N 0.432
ENSCJAG00000033322 Callithrix jacchus ENSCJAG00000033322 N 0.431
ENSCJAG00000014214 Callithrix jacchus ENSCJAG00000014214 N 0.431
D915_00818 Fasciola hepatica D915_00818 N 0.431
ENSCSAG00000013078 Chlorocebus sabaeus ENSCSAG00000013078 N 0.431
ENSBTAG00000031711 Bos taurus ENSBTAG00000031711 N 0.431
ENSSSCG00000024283 Sus scrofa ENSSSCG00000024283 N 0.431
ENSMPUG00000018359 Mustela putorius furo ENSMPUG00000018359 N 0.431
LOC688583 Rattus norvegicus ENSRNOG00000050910 N 0.431
ENSSSCG00000020770 Sus scrofa ENSSSCG00000020770 N 0.431
HMGB3 Oryctolagus cuniculus ENSOCUG00000024959 N 0.431
Hsal_13110--XP_001121384.1_APIME Harpegnathos saltator Hsal_13110--XP_001121384.1_APIME N 0.430
ENSSTOG00000012404 Ictidomys tridecemlineatus ENSSTOG00000012404 N 0.430
Cflo_05895--XP_001121384.1_APIME Camponotus floridanus Cflo_05895--XP_001121384.1_APIME N 0.430
AATE018776 Anopheles atroparvus AATE018776 N 0.429
AFAF003948 Anopheles farauti AFAF003948 N 0.429
AFUN010134 Anopheles funestus AFUN010134 N 0.429
AMAM015540 Anopheles maculatus AMAM015540 N 0.429
ADIR011701 Anopheles dirus ADIR011701 N 0.429
ACUA021022 Anopheles culicifacies ACUA021022 N 0.429
AARA010318 Anopheles arabiensis AARA010318 N 0.429
AGAP000005 Anopheles gambiae AGAP000005 N 0.429
AMEC021909 Anopheles melas AMEC021909 N 0.429
AALB006743 Anopheles albimanus AALB006743 N 0.429
AMEM017336 Anopheles merus AMEM017336 N 0.429
AAEL011380 Aedes aegypti AAEL011380 N 0.429
ADAC001494 Anopheles darlingi ADAC001494 N 0.429
AMIN005344 Anopheles minimus AMIN005344 N 0.429
ASIS000124 Anopheles sinensis ASIS000124 N 0.429
Aqu1.227714 Amphimedon queenslandica Aqu1.227714 N 0.428
SINV22586 Solenopsis invicta SINV22586 N 0.426
ACEP16613 Atta cephalotes ACEP16613 N 0.426
DAPPUDRAFT_306496 Daphnia pulex DAPPUDRAFT_306496 N 0.424
BXY_1714600 Bursaphelenchus xylophilus BXY_1714600 N 0.424
SROB_0000153901 Schistosoma rodhaini SROB_0000153901 N 0.423
SMTD_0001194601 Schistosoma mattheei SMTD_0001194601 N 0.423
SCUD_0000020101 Schistosoma curassoni SCUD_0000020101 N 0.423
AATE010886 Anopheles atroparvus AATE010886 N 0.423
Smp_000980 Schistosoma mansoni Smp_000980 N 0.423
GG17955 Drosophila erecta FBgn0110175 N 0.422
GF19115 Drosophila ananassae FBgn0096126 N 0.422
GA11488 Drosophila pseudoobscura FBgn0071539 N 0.422
ENSPFOG00000008464 Poecilia formosa ENSPFOG00000008464 N 0.422
Dsp1 Drosophila melanogaster FBgn0011764 N 0.422
GE17263 Drosophila yakuba FBgn0234741 N 0.422
ENSOCUG00000021132 Oryctolagus cuniculus ENSOCUG00000021132 N 0.422
GD17278 Drosophila simulans FBgn0188840 N 0.422
PHUM006290 Pediculus humanus PHUM006290 N 0.420
HMEL007340 Heliconius melpomene HMEL007340 N 0.419
SSLN_0000493501 Schistocephalus solidus SSLN_0000493501 N 0.418
GJ19445 Drosophila virilis FBgn0206588 N 0.418
HelroG157726 Helobdella robusta HelroG157726 N 0.418
GK25058 Drosophila willistoni FBgn0227017 N 0.418
DILT_0001497901 Diphyllobothrium latum DILT_0001497901 N 0.418
GI10980 Drosophila mojavensis FBgn0133743 N 0.418
GH12282 Drosophila grimshawi FBgn0119761 N 0.418
csin110255 Clonorchis sinensis csin110255 N 0.417
ENSCJAG00000007419 Callithrix jacchus ENSCJAG00000007419 N 0.417
T265_14643 Opisthorchis viverrini T265_14643 N 0.417
hmgb1a Takifugu rubripes ENSTRUG00000008452 N 0.417
D915_15256 Fasciola hepatica D915_15256 N 0.417
ENSDNOG00000005537 Dasypus novemcinctus ENSDNOG00000005537 N 0.417
ENSCJAG00000022832 Callithrix jacchus ENSCJAG00000022832 N 0.417
ASIS009950 Anopheles sinensis ASIS009950 N 0.416
CpipJ_CPIJ014043 Culex pipiens CpipJ_CPIJ014043 N 0.415
CPIJ014043 Culex quinquefasciatus CPIJ014043 N 0.415
AABR07025074.1 Rattus norvegicus ENSRNOG00000032550 N 0.415