hmg-1.2 (Caenorhabditis elegans)
Sox

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00505 (HMG_box) IPR000910 WBGene00001972 T333268_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Enables transcription cis-regulatory region binding activity. Involved in several processes, including gonad development; positive regulation of transcription by RNA polymerase II; and vulval development. Located in nucleus. Is expressed in several structures, including anal depressor muscle; intestine; nervous system; pharynx; and reproductive system. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis; congestive heart failure; and syndromic microphthalmia 13. Orthologous to several human genes including HMGB3 (high mobility group box 3). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No TFs with similar DNA binding domains

DNA Binding Domains

Protein ID Domain From To Sequence
F47D12.4a.1 Sox 47 113
F47D12.4a.1 Sox 135 203
F47D12.4a.2 Sox 47 113
F47D12.4a.2 Sox 135 203
F47D12.4b Sox 46 112
F47D12.4b Sox 134 202
F47D12.4c.1 Sox 47 115
F47D12.4c.1 Sox 133 201
F47D12.4c.2 Sox 47 115
F47D12.4c.2 Sox 133 201

Links

Other Sox family TFs
Other Caenorhabditis elegans TFs

Invalid Input OrderBy

153 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action