ENSBTAP00000049034-D1 (Bos grunniens)

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source
PF00505 (HMG_box) IPR000910 ENSBTAP00000049034-D1 T333681_2.00 GigaDB (2015-Oct-22)
NCBI Gene Info:
This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
No TFs with similar DNA binding domains

DNA Binding Domains

Protein ID Domain From To Sequence
ENSBTAP00000049034-D1 Sox 9 78
ENSBTAP00000049034-D1 Sox 91 158


Other Sox family TFs
Other Bos grunniens TFs

241 Related TFs

Name Species Gene ID Motif Evidence SR
ENSBTAG00000005098 Bos taurus ENSBTAG00000005098 N 0.741
ENSMPUG00000018359 Mustela putorius furo ENSMPUG00000018359 N 0.656
ENSSSCG00000020770 Sus scrofa ENSSSCG00000020770 N 0.656
ENSSSCG00000024283 Sus scrofa ENSSSCG00000024283 N 0.656
LOC688583 Rattus norvegicus ENSRNOG00000050910 N 0.654
ENSOGAG00000031959 Otolemur garnettii ENSOGAG00000031959 N 0.653
ENSCJAG00000033322 Callithrix jacchus ENSCJAG00000033322 N 0.653
ENSCSAG00000013078 Chlorocebus sabaeus ENSCSAG00000013078 N 0.653
ENSPANG00000020000 Papio anubis ENSPANG00000020000 N 0.651
ENSBTAG00000031711 Bos taurus ENSBTAG00000031711 N 0.648
ENSCJAG00000014214 Callithrix jacchus ENSCJAG00000014214 N 0.648
ENSPANG00000010595 Papio anubis ENSPANG00000010595 N 0.645
ENSCJAG00000007419 Callithrix jacchus ENSCJAG00000007419 N 0.639
HMGB3 Oryctolagus cuniculus ENSOCUG00000024959 N 0.639
ENSMLUG00000028530 Myotis lucifugus ENSMLUG00000028530 N 0.631
ENSMPUG00000020113 Mustela putorius furo ENSMPUG00000020113 N 0.619
ENSPANG00000023341 Papio anubis ENSPANG00000023341 N 0.613
ENSSTOG00000012404 Ictidomys tridecemlineatus ENSSTOG00000012404 N 0.612
Myotis_brandtii_HMGB3_10026974 Myotis brandtii Myotis_brandtii_HMGB3_10026974 N 0.612
ENSBTAP00000052990-D1 Bos grunniens ENSBTAP00000052990-D1 N 0.606
ENSMMUG00000007761 Macaca mulatta ENSMMUG00000007761 N 0.602
ENSMMUP00000010196 Macaca fascicularis ENSMMUP00000010196 N 0.602
ENSOGAG00000029272 Otolemur garnettii ENSOGAG00000029272 N 0.602
ENSCJAG00000004401 Callithrix jacchus ENSCJAG00000004401 N 0.602
ENSBTAG00000015315 Bos taurus ENSBTAG00000015315 N 0.601
ENSCSAG00000010707 Chlorocebus sabaeus ENSCSAG00000010707 N 0.594
ENSOCUG00000016030 Oryctolagus cuniculus ENSOCUG00000016030 N 0.590
ENSCJAG00000005187 Callithrix jacchus ENSCJAG00000005187 I 0.587
ENSOGAG00000006589 Otolemur garnettii ENSOGAG00000006589 N 0.584
AAH44009 Xenopus laevis AAH44009 N 0.583
ENSCJAG00000011146 Callithrix jacchus ENSCJAG00000011146 N 0.583
ENSCJAG00000007594 Callithrix jacchus ENSCJAG00000007594 N 0.582
ENSPANG00000025478 Papio anubis ENSPANG00000025478 N 0.581
ENSOCUG00000021132 Oryctolagus cuniculus ENSOCUG00000021132 N 0.580
ENSGGOG00000025769 Gorilla gorilla ENSGGOG00000025769 N 0.569
ENSGGOG00000026945 Gorilla gorilla ENSGGOG00000026945 N 0.568
ENSOCUG00000004133 Oryctolagus cuniculus ENSOCUG00000004133 N 0.568
ENSDNOG00000005537 Dasypus novemcinctus ENSDNOG00000005537 N 0.568
ENSPANG00000007527 Papio anubis ENSPANG00000007527 N 0.566
ENSOARG00000015382 Ovis aries ENSOARG00000015382 N 0.566
ENSOARG00000010383 Ovis aries ENSOARG00000010383 N 0.566
ENSOARG00000015955 Ovis aries ENSOARG00000015955 N 0.566
ENSCJAG00000022832 Callithrix jacchus ENSCJAG00000022832 N 0.564
Myotis_brandtii_Hmgb2_10018437 Myotis brandtii Myotis_brandtii_Hmgb2_10018437 N 0.561
Hmgb2l1 Rattus norvegicus ENSRNOG00000013167 N 0.559
Hmgb2 Rattus norvegicus ENSRNOG00000033321 N 0.559
RGD1561694 Rattus norvegicus ENSRNOG00000029107 N 0.559
ENSTBEG00000012989 Tupaia belangeri ENSTBEG00000012989 N 0.556
LOC108350839 Rattus norvegicus ENSRNOG00000038437 N 0.555
ENSDNOG00000033430 Dasypus novemcinctus ENSDNOG00000033430 N 0.552
hmgb2.S Xenopus laevis XB-GENE-1000251 N 0.552
HMGB2 Sus scrofa ENSSSCG00000009704 N 0.551
ENSGGOG00000027139 Gorilla gorilla ENSGGOG00000027139 N 0.550
ENSOCUG00000023449 Oryctolagus cuniculus ENSOCUG00000023449 N 0.549
ENSMICG00000016224 Microcebus murinus ENSMICG00000016224 N 0.549
ENSMMUG00000010106 Macaca mulatta ENSMMUG00000010106 I 0.547
ENSTBEG00000009427 Tupaia belangeri ENSTBEG00000009427 N 0.543
AABR07025074.1 Rattus norvegicus ENSRNOG00000032550 N 0.542
hmgb2a Danio rerio ENSDARG00000029722 N 0.542
ENSOGAG00000033658 Otolemur garnettii ENSOGAG00000033658 N 0.541
ENSPFOG00000008464 Poecilia formosa ENSPFOG00000008464 N 0.541
HMGB2 Macaca mulatta ENSMMUG00000020008 N 0.540
ENSMMUG00000018606 Macaca mulatta ENSMMUG00000018606 N 0.539
HMGB1 Monodelphis domestica ENSMODG00000004443 N 0.539
ENSCJAG00000033913 Callithrix jacchus ENSCJAG00000033913 N 0.538
ENSOGAG00000007401 Otolemur garnettii ENSOGAG00000007401 N 0.537
ENSCJAG00000003900 Callithrix jacchus ENSCJAG00000003900 N 0.537
hmgb1a Danio rerio ENSDARG00000099175 N 0.536
ENSPANG00000011105 Papio anubis ENSPANG00000011105 N 0.534
ENSCPOG00000003985 Cavia porcellus ENSCPOG00000003985 N 0.534
ENSAMXG00000014832 Astyanax mexicanus ENSAMXG00000014832 N 0.534
ENSPANG00000005029 Papio anubis ENSPANG00000005029 N 0.534
ENSECAG00000005186 Equus caballus ENSECAG00000005186 N 0.534
ENSOARG00000017078 Ovis aries ENSOARG00000017078 N 0.534
ENSOCUG00000027747 Oryctolagus cuniculus ENSOCUG00000027747 N 0.534
ENSMODG00000009238 Monodelphis domestica ENSMODG00000009238 N 0.534
Hmg1l1 Rattus norvegicus ENSRNOG00000034130 N 0.534
AC135696.1 Rattus norvegicus ENSRNOG00000058908 N 0.534
ENSSTOG00000000443 Ictidomys tridecemlineatus ENSSTOG00000000443 N 0.534
HMGB1 Microcebus murinus ENSMICG00000006213 N 0.534
ENSMMUG00000001275 Macaca mulatta ENSMMUG00000001275 N 0.534
ENSFCAG00000028961 Felis catus ENSFCAG00000028961 N 0.533
ENSOGAG00000032240 Otolemur garnettii ENSOGAG00000032240 N 0.533
ENSCJAG00000008384 Callithrix jacchus ENSCJAG00000008384 N 0.531
ENSCJAG00000007044 Callithrix jacchus ENSCJAG00000007044 N 0.531
ENSSTOG00000007009 Ictidomys tridecemlineatus ENSSTOG00000007009 N 0.530
ENSCJAG00000008378 Callithrix jacchus ENSCJAG00000008378 N 0.530
BAA06440 Xenopus laevis BAA06440 N 0.526
ENSTBEG00000016187 Tupaia belangeri ENSTBEG00000016187 N 0.525
ENSPPYG00000011668 Pongo abelii ENSPPYG00000011668 N 0.522
AAI68534 Xenopus tropicalis AAI68534 N 0.521
HMGB1 Bos taurus ENSBTAG00000014862 N 0.521
Hmg1l1 Rattus norvegicus ENSRNOG00000051482 N 0.520
ENSECAG00000003655 Equus caballus ENSECAG00000003655 N 0.515
ENSONIG00000019935 Oreochromis niloticus ENSONIG00000019935 N 0.514
hmgb1a Tetraodon nigroviridis ENSTNIG00000009909 N 0.513
ENSCJAG00000014197 Callithrix jacchus ENSCJAG00000014197 N 0.513
ENSOARG00000002938 Ovis aries ENSOARG00000002938 N 0.512
hmgb1a Takifugu rubripes ENSTRUG00000008452 N 0.512
ENSOGAG00000028007 Otolemur garnettii ENSOGAG00000028007 N 0.512
ENSCAFG00000023930 Canis familiaris ENSCAFG00000023930 N 0.512
hmgb3b Danio rerio ENSDARG00000006408 N 0.509
ENSOGAG00000028411 Otolemur garnettii ENSOGAG00000028411 N 0.508
ENSGMOG00000010060 Gadus morhua ENSGMOG00000010060 N 0.508
hmgb1a Oryzias latipes ENSORLG00000003400 N 0.507
Myotis_brandtii_Hmgb1_10026956 Myotis brandtii Myotis_brandtii_Hmgb1_10026956 N 0.507
ENSDNOG00000047452 Dasypus novemcinctus ENSDNOG00000047452 N 0.506
ENSOGAG00000030563 Otolemur garnettii ENSOGAG00000030563 N 0.505
ENSOGAG00000032325 Otolemur garnettii ENSOGAG00000032325 N 0.504
Myotis_brandtii_Hmgb1_10003213 Myotis brandtii Myotis_brandtii_Hmgb1_10003213 N 0.503
ENSOARG00000011611 Ovis aries ENSOARG00000011611 N 0.503
hmgb1b Gasterosteus aculeatus ENSGACG00000011447 N 0.502
hmgb2b Oryzias latipes ENSORLG00000018687 N 0.501
hmgb2b Tetraodon nigroviridis ENSTNIG00000004824 N 0.501
ENSPFOG00000004794 Poecilia formosa ENSPFOG00000004794 N 0.501
ENSCSAG00000017502 Chlorocebus sabaeus ENSCSAG00000017502 N 0.500
ENSCJAG00000031139 Callithrix jacchus ENSCJAG00000031139 I 0.500
ENSDNOG00000035552 Dasypus novemcinctus ENSDNOG00000035552 N 0.498
ENSLAFG00000030388 Loxodonta africana ENSLAFG00000030388 N 0.498
ENSOGAG00000032152 Otolemur garnettii ENSOGAG00000032152 N 0.497
hmgb2b Takifugu rubripes ENSTRUG00000005015 N 0.497
ENSXMAG00000011106 Xiphophorus maculatus ENSXMAG00000011106 N 0.497
hmgb1b Takifugu rubripes ENSTRUG00000004822 N 0.495
ENSPMAG00000007397 Petromyzon marinus ENSPMAG00000007397 N 0.495
hmgb2b Gasterosteus aculeatus ENSGACG00000001173 N 0.494
ENSOGAG00000034801 Otolemur garnettii ENSOGAG00000034801 N 0.493
RGD1563668 Rattus norvegicus ENSRNOG00000038478 N 0.491
ENSGGOG00000007804 Gorilla gorilla ENSGGOG00000007804 N 0.490
ENSAMXG00000014031 Astyanax mexicanus ENSAMXG00000014031 N 0.490
ENSOGAG00000032147 Otolemur garnettii ENSOGAG00000032147 N 0.490
ENSOGAG00000027410 Otolemur garnettii ENSOGAG00000027410 N 0.489
LOC100911637 Rattus norvegicus ENSRNOG00000048471 N 0.488
ENSCSAG00000001500 Chlorocebus sabaeus ENSCSAG00000001500 N 0.488
LOC100911637 Rattus norvegicus ENSRNOG00000048094 N 0.488
ENSAMEG00000011652 Ailuropoda melanoleuca ENSAMEG00000011652 N 0.486
ENSDNOG00000046844 Dasypus novemcinctus ENSDNOG00000046844 N 0.486
ENSOGAG00000010941 Otolemur garnettii ENSOGAG00000010941 N 0.485
ENSONIG00000005505 Oreochromis niloticus ENSONIG00000005505 N 0.485
ENSOGAG00000033437 Otolemur garnettii ENSOGAG00000033437 N 0.481
ENSBTAP00000049357-D1 Bos grunniens ENSBTAP00000049357-D1 N 0.480
ENSTSYG00000003868 Tarsius syrichta ENSTSYG00000003868 N 0.480
ENSCJAG00000007095 Callithrix jacchus ENSCJAG00000007095 N 0.480
ENSXMAG00000006844 Xiphophorus maculatus ENSXMAG00000006844 N 0.479
ENSPFOG00000004533 Poecilia formosa ENSPFOG00000004533 N 0.479
ENSOGAG00000030052 Otolemur garnettii ENSOGAG00000030052 N 0.478
AAH73449 Xenopus laevis AAH73449 N 0.478
AAC59859 Xenopus laevis AAC59859 N 0.478
SMAR013695 Strigamia maritima SMAR013695 N 0.477
ENSOARG00000020499 Ovis aries ENSOARG00000020499 N 0.476
ENSMMUG00000002662 Macaca mulatta ENSMMUG00000002662 N 0.476
Hmgb1-ps3 Rattus norvegicus ENSRNOG00000032420 N 0.476
ENSGGOG00000025109 Gorilla gorilla ENSGGOG00000025109 N 0.476
ENSMICG00000010120 Microcebus murinus ENSMICG00000010120 N 0.475
ENSBTAG00000020685 Bos taurus ENSBTAG00000020685 N 0.473
ENSGGOG00000023427 Gorilla gorilla ENSGGOG00000023427 N 0.472
ENSMMUP00000003419 Macaca fascicularis ENSMMUP00000003419 N 0.472
HelroG157726 Helobdella robusta HelroG157726 N 0.471
ENSOARG00000005357 Ovis aries ENSOARG00000005357 N 0.470
ENSTBEG00000005874 Tupaia belangeri ENSTBEG00000005874 N 0.469
Sakowv30042012m.g Saccoglossus kowalevskii Sakowv30042012m.g N 0.469
ENSOGAG00000027183 Otolemur garnettii ENSOGAG00000027183 N 0.468
ENSMMUG00000002541 Macaca mulatta ENSMMUG00000002541 I 0.467
ENSTSYG00000012587 Tarsius syrichta ENSTSYG00000012587 N 0.467
ENSMODG00000004606 Monodelphis domestica ENSMODG00000004606 N 0.464
SMU15027649 Schmidtea mediterranea SMU15027649 N 0.464
ENSCSAVG00000000341 Ciona savignyi ENSCSAVG00000000341 N 0.463
CapteG158220 Capitella teleta CapteG158220 N 0.463
ENSTBEG00000014925 Tupaia belangeri ENSTBEG00000014925 N 0.462
ENSMMUP00000039817 Macaca fascicularis ENSMMUP00000039817 N 0.462
tetur02g08260 Tetranychus urticae tetur02g08260 N 0.460
tetur02g08340 Tetranychus urticae tetur02g08340 N 0.460
ENSGMOG00000010657 Gadus morhua ENSGMOG00000010657 N 0.456
Aqu1.227714 Amphimedon queenslandica Aqu1.227714 N 0.456
ENSOGAG00000029748 Otolemur garnettii ENSOGAG00000029748 N 0.456
ENSPANG00000011772 Papio anubis ENSPANG00000011772 N 0.453
ENSMEUG00000011289 Macropus eugenii ENSMEUG00000011289 N 0.452
ENSCJAG00000014991 Callithrix jacchus ENSCJAG00000014991 N 0.452
ENSMMUG00000019832 Macaca mulatta ENSMMUG00000019832 N 0.451
hmg1/2 Ciona intestinalis ENSCING00000004075 N 0.450
ENSCSAG00000015385 Chlorocebus sabaeus ENSCSAG00000015385 N 0.448
AABR07019870.1 Rattus norvegicus ENSRNOG00000038033 N 0.447
ENSDNOG00000041663 Dasypus novemcinctus ENSDNOG00000041663 N 0.445
ENSGGOG00000025145 Gorilla gorilla ENSGGOG00000025145 N 0.445
ENSOGAG00000024497 Otolemur garnettii ENSOGAG00000024497 N 0.445
ENSETEG00000009246 Echinops telfairi ENSETEG00000009246 N 0.444
CPIJ014043 Culex quinquefasciatus CPIJ014043 N 0.443
CpipJ_CPIJ014043 Culex pipiens CpipJ_CPIJ014043 N 0.443
ISCW017350 Ixodes scapularis ISCW017350 N 0.443
ENSOGAG00000033253 Otolemur garnettii ENSOGAG00000033253 N 0.442
ENSTBEG00000015758 Tupaia belangeri ENSTBEG00000015758 N 0.440
SPU_005572 Strongylocentrotus purpuratus SPU_005572 N 0.440
ACYPI007949 Acyrthosiphon pisum ACYPI007949 N 0.438
HMEL007340 Heliconius melpomene HMEL007340 N 0.433
ENSTBEG00000017117 Tupaia belangeri ENSTBEG00000017117 N 0.433
LotgiG200052 Lottia gigantea LotgiG200052 N 0.432
ASIS000124 Anopheles sinensis ASIS000124 N 0.432
ENSDNOG00000042649 Dasypus novemcinctus ENSDNOG00000042649 N 0.429
BGIBMGA001132 Bombyx mori BGIBMGA001132 N 0.429
ACUA021022 Anopheles culicifacies ACUA021022 N 0.428
AATE018776 Anopheles atroparvus AATE018776 N 0.428
MDOA008812 Musca domestica MDOA008812 N 0.428
AALB006743 Anopheles albimanus AALB006743 N 0.428
ADIR011701 Anopheles dirus ADIR011701 N 0.428
AFAF003948 Anopheles farauti AFAF003948 N 0.428
AMEC021909 Anopheles melas AMEC021909 N 0.428
AMEM017336 Anopheles merus AMEM017336 N 0.428
AMAM015540 Anopheles maculatus AMAM015540 N 0.428
AAEL011380 Aedes aegypti AAEL011380 N 0.428
AMIN005344 Anopheles minimus AMIN005344 N 0.428
AFUN010134 Anopheles funestus AFUN010134 N 0.428
AEPI002924 Anopheles epiroticus AEPI002924 N 0.428
AARA010318 Anopheles arabiensis AARA010318 N 0.428
HelroG157878 Helobdella robusta HelroG157878 N 0.428
AGAP000005 Anopheles gambiae AGAP000005 N 0.428
ADAC001494 Anopheles darlingi ADAC001494 N 0.428
Cflo_05895--XP_001121384.1_APIME Camponotus floridanus Cflo_05895--XP_001121384.1_APIME N 0.427
ACEP16613 Atta cephalotes ACEP16613 N 0.427
Hsal_13110--XP_001121384.1_APIME Harpegnathos saltator Hsal_13110--XP_001121384.1_APIME N 0.427
Hba_13817 Heterorhabditis bacteriophora Hba_13817 N 0.427
NV15664 Nasonia vitripennis NV15664 N 0.427
SINV22586 Solenopsis invicta SINV22586 N 0.427
HCOI00860100 Haemonchus contortus HCOI00860100 N 0.425
TELCIR_07111 Teladorsagia circumcincta TELCIR_07111 N 0.425
NBR_0000911001 Nippostrongylus brasiliensis NBR_0000911001 N 0.425
NECAME_09126 Necator americanus NECAME_09126 N 0.425
ACOC_0000768601 Angiostrongylus costaricensis ACOC_0000768601 N 0.425
DME_0001055201 Dracunculus medinensis DME_0001055201 N 0.421
ACAC_0001052301 Angiostrongylus cantonensis ACAC_0001052301 N 0.420
PTRK_0000986200 Parastrongyloides trichosuri PTRK_0000986200 N 0.420
SPAL_0001030300 Strongyloides papillosus SPAL_0001030300 N 0.420
SSTP_0000371800 Strongyloides stercoralis SSTP_0000371800 N 0.420
ENSOARG00000019147 Ovis aries ENSOARG00000019147 N 0.420
SVE_0494300 Strongyloides venezuelensis SVE_0494300 N 0.420
GI10980 Drosophila mojavensis FBgn0133743 N 0.418
L889_g13533 Steinernema feltiae L889_g13533 N 0.418
GH12282 Drosophila grimshawi FBgn0119761 N 0.418
Alligator_sinensis_CCG007907.1 Alligator sinensis Alligator_sinensis_CCG007907.1 N 0.418
TTRE_0000338301 Trichuris trichiura TTRE_0000338301 N 0.417
ENSTBEG00000015340 Tupaia belangeri ENSTBEG00000015340 N 0.417
ENSOGAG00000033550 Otolemur garnettii ENSOGAG00000033550 N 0.417
AABR07060165.1 Rattus norvegicus ENSRNOG00000048544 N 0.415