ENSBTAP00000049357-D1 (Bos grunniens)
Sox

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source
PF00505 (HMG_box) IPR000910 ENSBTAP00000049357-D1 T333682_2.00 GigaDB (2015-Oct-22)
NCBI Gene Info:
This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No TFs with similar DNA binding domains

DNA Binding Domains

Protein ID Domain From To Sequence
ENSBTAP00000049357-D1 Sox 3 70
ENSBTAP00000049357-D1 Sox 85 153

Links

Other Sox family TFs
Other Bos grunniens TFs

216 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
HMGB1 Bos taurus ENSBTAG00000014862 N 0.648
Hmg1l1 Rattus norvegicus ENSRNOG00000034130 N 0.648
ENSPANG00000011105 Papio anubis ENSPANG00000011105 N 0.648
ENSPANG00000005029 Papio anubis ENSPANG00000005029 N 0.648
ENSMODG00000009238 Monodelphis domestica ENSMODG00000009238 N 0.648
ENSOARG00000017078 Ovis aries ENSOARG00000017078 N 0.648
ENSMMUG00000001275 Macaca mulatta ENSMMUG00000001275 N 0.648
ENSECAG00000005186 Equus caballus ENSECAG00000005186 N 0.648
ENSCPOG00000003985 Cavia porcellus ENSCPOG00000003985 N 0.648
HMGB1 Microcebus murinus ENSMICG00000006213 N 0.648
ENSSTOG00000000443 Ictidomys tridecemlineatus ENSSTOG00000000443 N 0.648
AC135696.1 Rattus norvegicus ENSRNOG00000058908 N 0.648
ENSCJAG00000008384 Callithrix jacchus ENSCJAG00000008384 N 0.645
ENSCJAG00000008378 Callithrix jacchus ENSCJAG00000008378 N 0.644
ENSOCUG00000004133 Oryctolagus cuniculus ENSOCUG00000004133 N 0.644
ENSPPYG00000011668 Pongo abelii ENSPPYG00000011668 N 0.639
Hmg1l1 Rattus norvegicus ENSRNOG00000051482 N 0.634
ENSCJAG00000022832 Callithrix jacchus ENSCJAG00000022832 N 0.631
ENSECAG00000003655 Equus caballus ENSECAG00000003655 N 0.629
ENSDNOG00000005537 Dasypus novemcinctus ENSDNOG00000005537 N 0.628
Myotis_brandtii_Hmgb1_10026956 Myotis brandtii Myotis_brandtii_Hmgb1_10026956 N 0.625
LOC108350839 Rattus norvegicus ENSRNOG00000038437 N 0.624
ENSOGAG00000028411 Otolemur garnettii ENSOGAG00000028411 N 0.622
Myotis_brandtii_Hmgb2_10018437 Myotis brandtii Myotis_brandtii_Hmgb2_10018437 N 0.620
ENSOARG00000011611 Ovis aries ENSOARG00000011611 N 0.617
ENSPANG00000007527 Papio anubis ENSPANG00000007527 N 0.615
ENSOARG00000015955 Ovis aries ENSOARG00000015955 N 0.615
ENSOARG00000015382 Ovis aries ENSOARG00000015382 N 0.615
ENSOARG00000010383 Ovis aries ENSOARG00000010383 N 0.615
ENSOGAG00000027410 Otolemur garnettii ENSOGAG00000027410 N 0.614
ENSTBEG00000016187 Tupaia belangeri ENSTBEG00000016187 N 0.612
AABR07025074.1 Rattus norvegicus ENSRNOG00000032550 N 0.611
Myotis_brandtii_Hmgb1_10003213 Myotis brandtii Myotis_brandtii_Hmgb1_10003213 N 0.611
ENSTBEG00000009427 Tupaia belangeri ENSTBEG00000009427 N 0.610
Hmgb2 Rattus norvegicus ENSRNOG00000033321 N 0.609
Hmgb2l1 Rattus norvegicus ENSRNOG00000013167 N 0.609
RGD1561694 Rattus norvegicus ENSRNOG00000029107 N 0.606
ENSOGAG00000032152 Otolemur garnettii ENSOGAG00000032152 N 0.605
ENSCAFG00000023930 Canis familiaris ENSCAFG00000023930 N 0.604
ENSMICG00000016224 Microcebus murinus ENSMICG00000016224 N 0.603
ENSOCUG00000021132 Oryctolagus cuniculus ENSOCUG00000021132 N 0.601
LOC100911637 Rattus norvegicus ENSRNOG00000048094 N 0.598
LOC100911637 Rattus norvegicus ENSRNOG00000048471 N 0.598
hmgb2.S Xenopus laevis XB-GENE-1000251 N 0.596
ENSTBEG00000012989 Tupaia belangeri ENSTBEG00000012989 N 0.596
ENSOARG00000005357 Ovis aries ENSOARG00000005357 N 0.593
Hmgb1-ps3 Rattus norvegicus ENSRNOG00000032420 N 0.590
hmgb1a Danio rerio ENSDARG00000099175 N 0.590
ENSOGAG00000033437 Otolemur garnettii ENSOGAG00000033437 N 0.589
ENSDNOG00000046844 Dasypus novemcinctus ENSDNOG00000046844 N 0.588
ENSOGAG00000030052 Otolemur garnettii ENSOGAG00000030052 N 0.587
ENSOGAG00000032147 Otolemur garnettii ENSOGAG00000032147 N 0.587
ENSOCUG00000023449 Oryctolagus cuniculus ENSOCUG00000023449 N 0.584
ENSFCAG00000028961 Felis catus ENSFCAG00000028961 N 0.583
HMGB2 Sus scrofa ENSSSCG00000009704 N 0.581
BAA06440 Xenopus laevis BAA06440 N 0.580
ENSBTAG00000020685 Bos taurus ENSBTAG00000020685 N 0.580
ENSAMXG00000014832 Astyanax mexicanus ENSAMXG00000014832 N 0.578
ENSPFOG00000008464 Poecilia formosa ENSPFOG00000008464 N 0.578
ENSOGAG00000032240 Otolemur garnettii ENSOGAG00000032240 N 0.576
hmgb1a Takifugu rubripes ENSTRUG00000008452 N 0.576
HMGB2 Macaca mulatta ENSMMUG00000020008 N 0.576
RGD1563668 Rattus norvegicus ENSRNOG00000038478 N 0.575
AAH73449 Xenopus laevis AAH73449 N 0.573
AAC59859 Xenopus laevis AAC59859 N 0.573
ENSOCUG00000027747 Oryctolagus cuniculus ENSOCUG00000027747 N 0.570
ENSDNOG00000047452 Dasypus novemcinctus ENSDNOG00000047452 N 0.569
HMGB1 Monodelphis domestica ENSMODG00000004443 N 0.566
ENSXMAG00000006844 Xiphophorus maculatus ENSXMAG00000006844 N 0.565
ENSOCUG00000016030 Oryctolagus cuniculus ENSOCUG00000016030 N 0.565
hmgb1a Tetraodon nigroviridis ENSTNIG00000009909 N 0.565
ENSTSYG00000003868 Tarsius syrichta ENSTSYG00000003868 N 0.564
ENSMMUG00000019832 Macaca mulatta ENSMMUG00000019832 N 0.563
ENSTBEG00000014925 Tupaia belangeri ENSTBEG00000014925 N 0.562
ENSONIG00000005505 Oreochromis niloticus ENSONIG00000005505 N 0.559
ENSOGAG00000028007 Otolemur garnettii ENSOGAG00000028007 N 0.558
ENSGGOG00000007804 Gorilla gorilla ENSGGOG00000007804 N 0.558
hmgb2a Danio rerio ENSDARG00000029722 N 0.557
hmgb1b Takifugu rubripes ENSTRUG00000004822 N 0.557
ENSMEUG00000011289 Macropus eugenii ENSMEUG00000011289 N 0.556
ENSOGAG00000030563 Otolemur garnettii ENSOGAG00000030563 N 0.555
ENSONIG00000019935 Oreochromis niloticus ENSONIG00000019935 N 0.554
ENSCJAG00000014214 Callithrix jacchus ENSCJAG00000014214 N 0.554
ENSTBEG00000015758 Tupaia belangeri ENSTBEG00000015758 N 0.552
hmgb1a Oryzias latipes ENSORLG00000003400 N 0.551
ENSGMOG00000010060 Gadus morhua ENSGMOG00000010060 N 0.551
ENSCJAG00000033322 Callithrix jacchus ENSCJAG00000033322 N 0.549
ENSSSCG00000020770 Sus scrofa ENSSSCG00000020770 N 0.549
ENSMPUG00000018359 Mustela putorius furo ENSMPUG00000018359 N 0.549
hmgb2b Gasterosteus aculeatus ENSGACG00000001173 N 0.549
ENSSSCG00000024283 Sus scrofa ENSSSCG00000024283 N 0.549
LOC688583 Rattus norvegicus ENSRNOG00000050910 N 0.549
hmgb1b Gasterosteus aculeatus ENSGACG00000011447 N 0.549
ENSCSAG00000013078 Chlorocebus sabaeus ENSCSAG00000013078 N 0.549
ENSGMOG00000010657 Gadus morhua ENSGMOG00000010657 N 0.548
ENSPFOG00000004533 Poecilia formosa ENSPFOG00000004533 N 0.547
ENSSTOG00000007009 Ictidomys tridecemlineatus ENSSTOG00000007009 N 0.546
AABR07019870.1 Rattus norvegicus ENSRNOG00000038033 N 0.546
ENSGGOG00000025109 Gorilla gorilla ENSGGOG00000025109 N 0.545
ENSCJAG00000014197 Callithrix jacchus ENSCJAG00000014197 N 0.545
ENSCJAG00000014991 Callithrix jacchus ENSCJAG00000014991 N 0.543
ENSDNOG00000041663 Dasypus novemcinctus ENSDNOG00000041663 N 0.543
ENSOGAG00000034801 Otolemur garnettii ENSOGAG00000034801 N 0.543
ENSTBEG00000017117 Tupaia belangeri ENSTBEG00000017117 N 0.543
ENSBTAG00000031711 Bos taurus ENSBTAG00000031711 N 0.543
ENSOGAG00000029748 Otolemur garnettii ENSOGAG00000029748 N 0.542
ENSPFOG00000004794 Poecilia formosa ENSPFOG00000004794 N 0.540
ENSXMAG00000011106 Xiphophorus maculatus ENSXMAG00000011106 N 0.540
hmgb2b Oryzias latipes ENSORLG00000018687 N 0.540
hmgb2b Takifugu rubripes ENSTRUG00000005015 N 0.540
hmgb2b Tetraodon nigroviridis ENSTNIG00000004824 N 0.540
ENSMMUP00000039817 Macaca fascicularis ENSMMUP00000039817 N 0.537
ENSOGAG00000033550 Otolemur garnettii ENSOGAG00000033550 N 0.537
ENSMODG00000004606 Monodelphis domestica ENSMODG00000004606 N 0.537
ENSOGAG00000032325 Otolemur garnettii ENSOGAG00000032325 N 0.533
ENSOGAG00000010941 Otolemur garnettii ENSOGAG00000010941 N 0.532
ENSSTOG00000012404 Ictidomys tridecemlineatus ENSSTOG00000012404 N 0.531
ENSPANG00000010595 Papio anubis ENSPANG00000010595 N 0.530
ENSCJAG00000007095 Callithrix jacchus ENSCJAG00000007095 N 0.529
HMGB3 Oryctolagus cuniculus ENSOCUG00000024959 N 0.528
Myotis_brandtii_HMGB3_10026974 Myotis brandtii Myotis_brandtii_HMGB3_10026974 N 0.527
ENSMLUG00000028530 Myotis lucifugus ENSMLUG00000028530 N 0.524
AAI68534 Xenopus tropicalis AAI68534 N 0.523
ENSMMUG00000002662 Macaca mulatta ENSMMUG00000002662 N 0.522
ENSTBEG00000015340 Tupaia belangeri ENSTBEG00000015340 N 0.520
ENSAMEG00000011652 Ailuropoda melanoleuca ENSAMEG00000011652 N 0.520
ENSTBEG00000005874 Tupaia belangeri ENSTBEG00000005874 N 0.520
ENSTSYG00000012587 Tarsius syrichta ENSTSYG00000012587 N 0.520
ENSCJAG00000007419 Callithrix jacchus ENSCJAG00000007419 N 0.515
ENSTBEG00000005706 Tupaia belangeri ENSTBEG00000005706 N 0.515
ENSCJAG00000033913 Callithrix jacchus ENSCJAG00000033913 N 0.513
ENSCSAG00000015385 Chlorocebus sabaeus ENSCSAG00000015385 N 0.512
ENSCJAG00000011146 Callithrix jacchus ENSCJAG00000011146 N 0.510
ENSCJAG00000007594 Callithrix jacchus ENSCJAG00000007594 N 0.508
ENSBTAG00000015315 Bos taurus ENSBTAG00000015315 N 0.505
ENSBTAP00000052990-D1 Bos grunniens ENSBTAP00000052990-D1 N 0.505
ENSOGAG00000031959 Otolemur garnettii ENSOGAG00000031959 N 0.504
ENSCJAG00000005187 Callithrix jacchus ENSCJAG00000005187 I 0.502
ENSAMXG00000014031 Astyanax mexicanus ENSAMXG00000014031 N 0.501
ENSMPUG00000020113 Mustela putorius furo ENSMPUG00000020113 N 0.498
ENSPANG00000025478 Papio anubis ENSPANG00000025478 N 0.496
ENSDNOG00000042649 Dasypus novemcinctus ENSDNOG00000042649 N 0.496
ENSCSAG00000010707 Chlorocebus sabaeus ENSCSAG00000010707 N 0.494
ENSPMAG00000007397 Petromyzon marinus ENSPMAG00000007397 N 0.493
ENSGGOG00000026945 Gorilla gorilla ENSGGOG00000026945 N 0.493
ENSOGAG00000024497 Otolemur garnettii ENSOGAG00000024497 N 0.492
ENSPANG00000023341 Papio anubis ENSPANG00000023341 N 0.492
hmgb3b Danio rerio ENSDARG00000006408 N 0.490
ENSCJAG00000004401 Callithrix jacchus ENSCJAG00000004401 N 0.490
ENSOGAG00000029272 Otolemur garnettii ENSOGAG00000029272 N 0.490
ENSOGAG00000033253 Otolemur garnettii ENSOGAG00000033253 N 0.489
ENSMMUG00000018606 Macaca mulatta ENSMMUG00000018606 N 0.488
ENSLAFG00000030388 Loxodonta africana ENSLAFG00000030388 N 0.487
AAH44009 Xenopus laevis AAH44009 N 0.485
ENSGGOG00000025769 Gorilla gorilla ENSGGOG00000025769 N 0.482
ENSETEG00000009246 Echinops telfairi ENSETEG00000009246 N 0.480
ENSBTAG00000005098 Bos taurus ENSBTAG00000005098 N 0.480
ENSCJAG00000010744 Callithrix jacchus ENSCJAG00000010744 N 0.480
ENSBTAP00000049034-D1 Bos grunniens ENSBTAP00000049034-D1 N 0.480
ENSCSAG00000012719 Chlorocebus sabaeus ENSCSAG00000012719 N 0.477
ENSETEG00000013458 Echinops telfairi ENSETEG00000013458 N 0.476
ENSMEUG00000009480 Macropus eugenii ENSMEUG00000009480 N 0.476
ENSBTAP00000049357-D3 Bos grunniens ENSBTAP00000049357-D3 N 0.472
ENSMMUG00000010106 Macaca mulatta ENSMMUG00000010106 I 0.472
ENSOARG00000019147 Ovis aries ENSOARG00000019147 N 0.469
ENSCSAVG00000000341 Ciona savignyi ENSCSAVG00000000341 N 0.468
AABR07060165.1 Rattus norvegicus ENSRNOG00000048544 N 0.468
ENSTBEG00000013995 Tupaia belangeri ENSTBEG00000013995 N 0.466
SMAR013695 Strigamia maritima SMAR013695 N 0.465
ENSMEUG00000016024 Macropus eugenii ENSMEUG00000016024 N 0.465
ENSPANG00000020000 Papio anubis ENSPANG00000020000 N 0.464
HelroG157878 Helobdella robusta HelroG157878 N 0.464
CapteG158220 Capitella teleta CapteG158220 N 0.463
ENSOGAG00000027183 Otolemur garnettii ENSOGAG00000027183 N 0.463
HelroG157726 Helobdella robusta HelroG157726 N 0.463
HMGB1 Tupaia belangeri ENSTBEG00000013046 N 0.462
Alligator_sinensis_CCG007907.1 Alligator sinensis Alligator_sinensis_CCG007907.1 N 0.462
ENSMPUG00000000121 Mustela putorius furo ENSMPUG00000000121 N 0.458
ENSOGAG00000006589 Otolemur garnettii ENSOGAG00000006589 N 0.457
ENSMICG00000000573 Microcebus murinus ENSMICG00000000573 N 0.456
hmg1/2 Ciona intestinalis ENSCING00000004075 N 0.455
Sakowv30042012m.g Saccoglossus kowalevskii Sakowv30042012m.g N 0.452
ENSDNOG00000033430 Dasypus novemcinctus ENSDNOG00000033430 N 0.451
ENSCJAG00000017053 Callithrix jacchus ENSCJAG00000017053 N 0.449
ENSGGOG00000027139 Gorilla gorilla ENSGGOG00000027139 N 0.448
ENSCJAG00000003900 Callithrix jacchus ENSCJAG00000003900 N 0.447
ENSOGAG00000028737 Otolemur garnettii ENSOGAG00000028737 N 0.447
ENSPPYG00000020229 Pongo abelii ENSPPYG00000020229 N 0.444
ENSMMUP00000017448 Macaca fascicularis ENSMMUP00000017448 N 0.440
ENSMMUG00000013266 Macaca mulatta ENSMMUG00000013266 N 0.440
ENSCHOG00000001924 Choloepus hoffmanni ENSCHOG00000001924 N 0.439
ENSMICG00000010120 Microcebus murinus ENSMICG00000010120 N 0.438
ENSOGAG00000007401 Otolemur garnettii ENSOGAG00000007401 N 0.436
PHUM006290 Pediculus humanus PHUM006290 N 0.436
ENSMMUP00000010196 Macaca fascicularis ENSMMUP00000010196 N 0.434
ACYPI007949 Acyrthosiphon pisum ACYPI007949 N 0.434
ENSMMUG00000007761 Macaca mulatta ENSMMUG00000007761 N 0.434
ENSOARG00000020499 Ovis aries ENSOARG00000020499 N 0.433
HMGB1 Gorilla gorilla ENSGGOG00000026606 N 0.430
ENSGGOG00000023265 Gorilla gorilla ENSGGOG00000023265 N 0.430
PXEA_0002175501 Protopolystoma xenopodis PXEA_0002175501 N 0.429
tetur02g08340 Tetranychus urticae tetur02g08340 N 0.427
tetur02g08260 Tetranychus urticae tetur02g08260 N 0.427
NV15664 Nasonia vitripennis NV15664 N 0.425
Gfo_R010508 Geospiza fortis Gfo_R010508 N 0.424
ENSTBEG00000013375 Tupaia belangeri ENSTBEG00000013375 N 0.423
CpipJ_CPIJ014043 Culex pipiens CpipJ_CPIJ014043 N 0.423
CPIJ014043 Culex quinquefasciatus CPIJ014043 N 0.423
ENSTGUG00000006267 Taeniopygia guttata ENSTGUG00000006267 N 0.421
ENSCSAG00000001500 Chlorocebus sabaeus ENSCSAG00000001500 N 0.420
LotgiG200052 Lottia gigantea LotgiG200052 N 0.420
MCOS_0000526101 Mesocestoides corti MCOS_0000526101 N 0.418
TsM_000115400 Taenia solium TsM_000115400 N 0.418
ISCW017350 Ixodes scapularis ISCW017350 N 0.418
EmuJ_001049000 Echinococcus multilocularis EmuJ_001049000 N 0.418
ENSDNOG00000036626 Dasypus novemcinctus ENSDNOG00000036626 N 0.416