ENSBTAP00000052990-D1 (Bos grunniens)

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source
PF00505 (HMG_box) IPR000910 ENSBTAP00000052990-D1 T333684_2.00 GigaDB (2015-Oct-22)
NCBI Gene Info:
This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
No TFs with similar DNA binding domains

DNA Binding Domains

Protein ID Domain From To Sequence
ENSBTAP00000052990-D1 Sox 8 81
ENSBTAP00000052990-D1 Sox 94 161


Other Sox family TFs
Other Bos grunniens TFs

190 Related TFs

Name Species Gene ID Motif Evidence SR
ENSBTAG00000015315 Bos taurus ENSBTAG00000015315 N 0.736
ENSSSCG00000020770 Sus scrofa ENSSSCG00000020770 N 0.627
ENSMPUG00000018359 Mustela putorius furo ENSMPUG00000018359 N 0.627
ENSSSCG00000024283 Sus scrofa ENSSSCG00000024283 N 0.627
LOC688583 Rattus norvegicus ENSRNOG00000050910 N 0.624
ENSCJAG00000033322 Callithrix jacchus ENSCJAG00000033322 N 0.623
ENSCSAG00000013078 Chlorocebus sabaeus ENSCSAG00000013078 N 0.623
ENSCJAG00000007419 Callithrix jacchus ENSCJAG00000007419 N 0.622
ENSCJAG00000014214 Callithrix jacchus ENSCJAG00000014214 N 0.618
ENSBTAG00000031711 Bos taurus ENSBTAG00000031711 N 0.618
ENSPANG00000010595 Papio anubis ENSPANG00000010595 N 0.613
ENSSTOG00000012404 Ictidomys tridecemlineatus ENSSTOG00000012404 N 0.609
HMGB3 Oryctolagus cuniculus ENSOCUG00000024959 N 0.607
ENSBTAP00000049034-D1 Bos grunniens ENSBTAP00000049034-D1 N 0.606
ENSPANG00000023341 Papio anubis ENSPANG00000023341 N 0.606
ENSBTAG00000005098 Bos taurus ENSBTAG00000005098 N 0.606
ENSMLUG00000028530 Myotis lucifugus ENSMLUG00000028530 N 0.602
Myotis_brandtii_HMGB3_10026974 Myotis brandtii Myotis_brandtii_HMGB3_10026974 N 0.597
ENSOGAG00000031959 Otolemur garnettii ENSOGAG00000031959 N 0.596
ENSPANG00000020000 Papio anubis ENSPANG00000020000 N 0.593
ENSMPUG00000020113 Mustela putorius furo ENSMPUG00000020113 N 0.590
ENSCJAG00000007594 Callithrix jacchus ENSCJAG00000007594 N 0.581
ENSCSAG00000010707 Chlorocebus sabaeus ENSCSAG00000010707 N 0.580
ENSOCUG00000016030 Oryctolagus cuniculus ENSOCUG00000016030 N 0.578
ENSCJAG00000005187 Callithrix jacchus ENSCJAG00000005187 I 0.573
ENSCJAG00000004401 Callithrix jacchus ENSCJAG00000004401 N 0.573
ENSOGAG00000029272 Otolemur garnettii ENSOGAG00000029272 N 0.573
ENSOGAG00000006589 Otolemur garnettii ENSOGAG00000006589 N 0.568
ENSOCUG00000021132 Oryctolagus cuniculus ENSOCUG00000021132 N 0.567
ENSPANG00000025478 Papio anubis ENSPANG00000025478 N 0.567
ENSMMUP00000010196 Macaca fascicularis ENSMMUP00000010196 N 0.557
ENSMMUG00000007761 Macaca mulatta ENSMMUG00000007761 N 0.557
ENSGGOG00000026945 Gorilla gorilla ENSGGOG00000026945 N 0.554
AAH44009 Xenopus laevis AAH44009 N 0.553
ENSPANG00000007527 Papio anubis ENSPANG00000007527 N 0.552
ENSOCUG00000004133 Oryctolagus cuniculus ENSOCUG00000004133 N 0.552
ENSOARG00000010383 Ovis aries ENSOARG00000010383 N 0.552
ENSOARG00000015382 Ovis aries ENSOARG00000015382 N 0.552
ENSOARG00000015955 Ovis aries ENSOARG00000015955 N 0.552
ENSCJAG00000022832 Callithrix jacchus ENSCJAG00000022832 N 0.551
ENSDNOG00000005537 Dasypus novemcinctus ENSDNOG00000005537 N 0.551
ENSTBEG00000012989 Tupaia belangeri ENSTBEG00000012989 N 0.548
Myotis_brandtii_Hmgb2_10018437 Myotis brandtii Myotis_brandtii_Hmgb2_10018437 N 0.547
Hmgb2 Rattus norvegicus ENSRNOG00000033321 N 0.546
Hmgb2l1 Rattus norvegicus ENSRNOG00000013167 N 0.546
RGD1561694 Rattus norvegicus ENSRNOG00000029107 N 0.546
ENSCJAG00000011146 Callithrix jacchus ENSCJAG00000011146 N 0.544
ENSOCUG00000023449 Oryctolagus cuniculus ENSOCUG00000023449 N 0.536
ENSMICG00000016224 Microcebus murinus ENSMICG00000016224 N 0.536
ENSCJAG00000003900 Callithrix jacchus ENSCJAG00000003900 N 0.536
ENSDNOG00000033430 Dasypus novemcinctus ENSDNOG00000033430 N 0.536
HMGB2 Sus scrofa ENSSSCG00000009704 N 0.535
ENSTBEG00000009427 Tupaia belangeri ENSTBEG00000009427 N 0.534
AABR07025074.1 Rattus norvegicus ENSRNOG00000032550 N 0.529
ENSPFOG00000008464 Poecilia formosa ENSPFOG00000008464 N 0.528
ENSOGAG00000007401 Otolemur garnettii ENSOGAG00000007401 N 0.528
HMGB2 Macaca mulatta ENSMMUG00000020008 N 0.527
ENSGGOG00000025769 Gorilla gorilla ENSGGOG00000025769 N 0.523
hmgb2.S Xenopus laevis XB-GENE-1000251 N 0.523
ENSCJAG00000033913 Callithrix jacchus ENSCJAG00000033913 N 0.522
ENSOCUG00000027747 Oryctolagus cuniculus ENSOCUG00000027747 N 0.521
ENSPANG00000011105 Papio anubis ENSPANG00000011105 N 0.520
ENSPANG00000005029 Papio anubis ENSPANG00000005029 N 0.520
ENSECAG00000005186 Equus caballus ENSECAG00000005186 N 0.520
ENSFCAG00000028961 Felis catus ENSFCAG00000028961 N 0.520
Hmg1l1 Rattus norvegicus ENSRNOG00000034130 N 0.520
HMGB1 Microcebus murinus ENSMICG00000006213 N 0.520
ENSCPOG00000003985 Cavia porcellus ENSCPOG00000003985 N 0.520
ENSCJAG00000008384 Callithrix jacchus ENSCJAG00000008384 N 0.520
ENSSTOG00000000443 Ictidomys tridecemlineatus ENSSTOG00000000443 N 0.520
ENSOARG00000017078 Ovis aries ENSOARG00000017078 N 0.520
ENSGGOG00000027139 Gorilla gorilla ENSGGOG00000027139 N 0.520
ENSMMUG00000001275 Macaca mulatta ENSMMUG00000001275 N 0.520
AC135696.1 Rattus norvegicus ENSRNOG00000058908 N 0.520
ENSMODG00000009238 Monodelphis domestica ENSMODG00000009238 N 0.520
HMGB1 Monodelphis domestica ENSMODG00000004443 N 0.517
ENSCJAG00000008378 Callithrix jacchus ENSCJAG00000008378 N 0.516
ENSMMUG00000010106 Macaca mulatta ENSMMUG00000010106 I 0.516
hmgb2a Danio rerio ENSDARG00000029722 N 0.513
ENSSTOG00000007009 Ictidomys tridecemlineatus ENSSTOG00000007009 N 0.513
ENSTBEG00000016187 Tupaia belangeri ENSTBEG00000016187 N 0.512
ENSPPYG00000011668 Pongo abelii ENSPPYG00000011668 N 0.512
Myotis_brandtii_Hmgb1_10026956 Myotis brandtii Myotis_brandtii_Hmgb1_10026956 N 0.509
ENSOGAG00000033658 Otolemur garnettii ENSOGAG00000033658 N 0.509
ENSCAFG00000023930 Canis familiaris ENSCAFG00000023930 N 0.508
HMGB1 Bos taurus ENSBTAG00000014862 N 0.508
ENSOGAG00000027410 Otolemur garnettii ENSOGAG00000027410 N 0.508
ENSMMUG00000018606 Macaca mulatta ENSMMUG00000018606 N 0.507
hmgb1a Danio rerio ENSDARG00000099175 N 0.507
Hmg1l1 Rattus norvegicus ENSRNOG00000051482 N 0.507
Myotis_brandtii_Hmgb1_10003213 Myotis brandtii Myotis_brandtii_Hmgb1_10003213 N 0.506
AAI68534 Xenopus tropicalis AAI68534 N 0.505
ENSBTAP00000049357-D1 Bos grunniens ENSBTAP00000049357-D1 N 0.505
ENSECAG00000003655 Equus caballus ENSECAG00000003655 N 0.502
ENSOGAG00000032147 Otolemur garnettii ENSOGAG00000032147 N 0.500
hmgb1a Takifugu rubripes ENSTRUG00000008452 N 0.499
hmgb1a Tetraodon nigroviridis ENSTNIG00000009909 N 0.499
ENSONIG00000019935 Oreochromis niloticus ENSONIG00000019935 N 0.498
ENSOGAG00000030563 Otolemur garnettii ENSOGAG00000030563 N 0.498
LOC108350839 Rattus norvegicus ENSRNOG00000038437 N 0.497
BAA06440 Xenopus laevis BAA06440 N 0.497
ENSCJAG00000014197 Callithrix jacchus ENSCJAG00000014197 N 0.497
ENSOGAG00000028411 Otolemur garnettii ENSOGAG00000028411 N 0.495
ENSDNOG00000047452 Dasypus novemcinctus ENSDNOG00000047452 N 0.492
ENSCJAG00000007044 Callithrix jacchus ENSCJAG00000007044 N 0.492
ENSOGAG00000028007 Otolemur garnettii ENSOGAG00000028007 N 0.492
ENSGMOG00000010060 Gadus morhua ENSGMOG00000010060 N 0.491
ENSOARG00000011611 Ovis aries ENSOARG00000011611 N 0.490
hmgb1b Gasterosteus aculeatus ENSGACG00000011447 N 0.489
ENSAMXG00000014832 Astyanax mexicanus ENSAMXG00000014832 N 0.488
ENSOGAG00000032240 Otolemur garnettii ENSOGAG00000032240 N 0.488
ENSCJAG00000007095 Callithrix jacchus ENSCJAG00000007095 N 0.486
ENSDNOG00000046844 Dasypus novemcinctus ENSDNOG00000046844 N 0.485
hmgb2b Oryzias latipes ENSORLG00000018687 N 0.484
ENSOGAG00000010941 Otolemur garnettii ENSOGAG00000010941 N 0.484
ENSPFOG00000004794 Poecilia formosa ENSPFOG00000004794 N 0.484
hmgb2b Tetraodon nigroviridis ENSTNIG00000004824 N 0.484
ENSOGAG00000032152 Otolemur garnettii ENSOGAG00000032152 N 0.484
ENSCSAG00000001500 Chlorocebus sabaeus ENSCSAG00000001500 N 0.484
ENSTSYG00000003868 Tarsius syrichta ENSTSYG00000003868 N 0.484
ENSOARG00000002938 Ovis aries ENSOARG00000002938 N 0.482
ENSOARG00000020499 Ovis aries ENSOARG00000020499 N 0.482
ENSOGAG00000032325 Otolemur garnettii ENSOGAG00000032325 N 0.481
ENSXMAG00000011106 Xiphophorus maculatus ENSXMAG00000011106 N 0.481
hmgb2b Takifugu rubripes ENSTRUG00000005015 N 0.481
hmgb3b Danio rerio ENSDARG00000006408 N 0.480
ENSLAFG00000030388 Loxodonta africana ENSLAFG00000030388 N 0.480
hmgb2b Gasterosteus aculeatus ENSGACG00000001173 N 0.478
RGD1563668 Rattus norvegicus ENSRNOG00000038478 N 0.478
ENSMICG00000010120 Microcebus murinus ENSMICG00000010120 N 0.478
hmgb1a Oryzias latipes ENSORLG00000003400 N 0.478
ENSCJAG00000031139 Callithrix jacchus ENSCJAG00000031139 I 0.477
LOC100911637 Rattus norvegicus ENSRNOG00000048471 N 0.475
ENSGGOG00000007804 Gorilla gorilla ENSGGOG00000007804 N 0.475
LOC100911637 Rattus norvegicus ENSRNOG00000048094 N 0.475
ENSDNOG00000035552 Dasypus novemcinctus ENSDNOG00000035552 N 0.473
ENSAMXG00000014031 Astyanax mexicanus ENSAMXG00000014031 N 0.473
ENSAMEG00000011652 Ailuropoda melanoleuca ENSAMEG00000011652 N 0.472
ENSMMUP00000003419 Macaca fascicularis ENSMMUP00000003419 N 0.468
ENSTBEG00000005874 Tupaia belangeri ENSTBEG00000005874 N 0.465
AAC59859 Xenopus laevis AAC59859 N 0.465
AAH73449 Xenopus laevis AAH73449 N 0.465
ENSGGOG00000023427 Gorilla gorilla ENSGGOG00000023427 N 0.464
ENSMODG00000004606 Monodelphis domestica ENSMODG00000004606 N 0.464
ENSTSYG00000012587 Tarsius syrichta ENSTSYG00000012587 N 0.463
Hmgb1-ps3 Rattus norvegicus ENSRNOG00000032420 N 0.463
ENSMMUG00000002541 Macaca mulatta ENSMMUG00000002541 I 0.463
ENSMMUP00000039817 Macaca fascicularis ENSMMUP00000039817 N 0.462
ENSMMUG00000002662 Macaca mulatta ENSMMUG00000002662 N 0.460
ENSOGAG00000030052 Otolemur garnettii ENSOGAG00000030052 N 0.458
ENSBTAG00000020685 Bos taurus ENSBTAG00000020685 N 0.458
ENSOGAG00000034801 Otolemur garnettii ENSOGAG00000034801 N 0.457
ENSONIG00000005505 Oreochromis niloticus ENSONIG00000005505 N 0.455
HelroG157726 Helobdella robusta HelroG157726 N 0.455
ENSMEUG00000011289 Macropus eugenii ENSMEUG00000011289 N 0.454
ENSPMAG00000007397 Petromyzon marinus ENSPMAG00000007397 N 0.453
ENSOARG00000005357 Ovis aries ENSOARG00000005357 N 0.452
ENSCSAG00000017502 Chlorocebus sabaeus ENSCSAG00000017502 N 0.452
ENSXMAG00000006844 Xiphophorus maculatus ENSXMAG00000006844 N 0.450
ENSPFOG00000004533 Poecilia formosa ENSPFOG00000004533 N 0.450
hmgb1b Takifugu rubripes ENSTRUG00000004822 N 0.449
ENSTBEG00000014925 Tupaia belangeri ENSTBEG00000014925 N 0.449
ENSCJAG00000014991 Callithrix jacchus ENSCJAG00000014991 N 0.446
ENSOGAG00000033437 Otolemur garnettii ENSOGAG00000033437 N 0.445
Sakowv30042012m.g Saccoglossus kowalevskii Sakowv30042012m.g N 0.444
ENSCSAG00000015385 Chlorocebus sabaeus ENSCSAG00000015385 N 0.444
AABR07019870.1 Rattus norvegicus ENSRNOG00000038033 N 0.440
ENSOGAG00000029748 Otolemur garnettii ENSOGAG00000029748 N 0.436
ENSMMUG00000019832 Macaca mulatta ENSMMUG00000019832 N 0.435
CapteG158220 Capitella teleta CapteG158220 N 0.431
ENSDNOG00000041663 Dasypus novemcinctus ENSDNOG00000041663 N 0.429
ENSOGAG00000027183 Otolemur garnettii ENSOGAG00000027183 N 0.429
ENSDNOG00000042649 Dasypus novemcinctus ENSDNOG00000042649 N 0.429
SMAR013695 Strigamia maritima SMAR013695 N 0.428
ENSCSAVG00000000341 Ciona savignyi ENSCSAVG00000000341 N 0.426
SMU15027649 Schmidtea mediterranea SMU15027649 N 0.426
ENSOGAG00000033253 Otolemur garnettii ENSOGAG00000033253 N 0.425
ENSGMOG00000010657 Gadus morhua ENSGMOG00000010657 N 0.424
ENSETEG00000009246 Echinops telfairi ENSETEG00000009246 N 0.424
Aqu1.227714 Amphimedon queenslandica Aqu1.227714 N 0.424
tetur02g08260 Tetranychus urticae tetur02g08260 N 0.422
ENSPANG00000011772 Papio anubis ENSPANG00000011772 N 0.422
tetur02g08340 Tetranychus urticae tetur02g08340 N 0.422
ENSGGOG00000025109 Gorilla gorilla ENSGGOG00000025109 N 0.418
ENSOGAG00000033550 Otolemur garnettii ENSOGAG00000033550 N 0.417
ENSOARG00000019147 Ovis aries ENSOARG00000019147 N 0.416
ENSOARG00000005773 Ovis aries ENSOARG00000005773 N 0.416
ENSTBEG00000015340 Tupaia belangeri ENSTBEG00000015340 N 0.416
ENSTBEG00000017117 Tupaia belangeri ENSTBEG00000017117 N 0.416
SPU_005572 Strongylocentrotus purpuratus SPU_005572 N 0.415