snap_masked-nMf.1.1.scaf27159-processed-gene-0.2 (Meloidogyne floridensis)
Sox

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source
PF00505 (HMG_box) IPR000910 snap_masked-nMf.1.1.scaf27159-processed-gene-0.2 T336978_2.00 WormBase:ParaSite (2015-Oct-22)
NCBI Gene Info:
This gene encodes a member of the Smad family of signal transduction proteins. Smad proteins are phosphorylated and activated by transmembrane serine-threonine receptor kinases in response to transforming growth factor (TGF)-beta signaling. The product of this gene forms homomeric complexes and heteromeric complexes with other activated Smad proteins, which then accumulate in the nucleus and regulate the transcription of target genes. This protein binds to DNA and recognizes an 8-bp palindromic sequence (GTCTAGAC) called the Smad-binding element (SBE). The protein acts as a tumor suppressor and inhibits epithelial cell proliferation. It may also have an inhibitory effect on tumors by reducing angiogenesis and increasng blood vessel hyperpermeability. The encoded protein is a crucial component of the bone morphogenetic protein signaling pathway. The Smad proteins are subject to complex regulation by post-translational modifications. Mutations or deletions in this gene have been shown to result in pancreatic cancer, juvenile polyposis syndrome, and hereditary hemorrhagic telangiectasia syndrome. [provided by RefSeq, Aug 2017]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No TFs with similar DNA binding domains

DNA Binding Domains

Protein ID Domain From To Sequence
snap_masked-nMf.1.1.scaf27159-processed-gene-0.2-mRNA-1 Sox 20 88

Links

Other Sox family TFs
Other Meloidogyne floridensis TFs

115 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
Minc14081 Meloidogyne incognita Minc14081 N 0.741
maker-nMf.1.1.scaf01126-augustus-gene-0.13 Meloidogyne floridensis maker-nMf.1.1.scaf01126-augustus-gene-0.13 N 0.741
MhA1_Contig1809.frz3.gene8 Meloidogyne hapla MhA1_Contig1809.frz3.gene8 N 0.660
HPBE_0000083501 Heligmosomoides bakeri HPBE_0000083501 N 0.554
HPLM_0001658301 Haemonchus placei HPLM_0001658301 N 0.554
TELCIR_14354 Teladorsagia circumcincta TELCIR_14354 N 0.554
HCOI00569400 Haemonchus contortus HCOI00569400 N 0.554
GPLIN_000239300 Globodera pallida GPLIN_000239300 N 0.554
ANCCAN_03785 Ancylostoma caninum ANCCAN_03785 N 0.554
ANCCAN_09575 Ancylostoma caninum ANCCAN_09575 N 0.554
ANCCEY_02937 Ancylostoma ceylanicum ANCCEY_02937 N 0.554
ANCDUO_12071 Ancylostoma duodenale ANCDUO_12071 N 0.554
NECAME_16117 Necator americanus NECAME_16117 N 0.554
HCOI00022200 Haemonchus contortus HCOI00022200 N 0.554
OESDEN_12607 Oesophagostomum dentatum OESDEN_12607 N 0.554
SVUK_0000819801 Strongylus vulgaris SVUK_0000819801 N 0.554
OESDEN_21929 Oesophagostomum dentatum OESDEN_21929 N 0.554
ACAC_0000207501 Angiostrongylus cantonensis ACAC_0000207501 N 0.548
swsn-3 Caenorhabditis elegans WBGene00022182 N 0.528
EVEC_0000378901 Enterobius vermicularis EVEC_0000378901 N 0.523
CBG09815 Caenorhabditis briggsae CBG09815 N 0.521
DME_0000063901 Dracunculus medinensis DME_0000063901 N 0.509
nLs.2.1.2.g01047 Litomosoides sigmodontis nLs.2.1.2.g01047 N 0.502
EEL_0000522201 Elaeophora elaphi EEL_0000522201 N 0.502
LOAG_01279 Loa loa LOAG_01279 N 0.502
WUBG_07283 Wuchereria bancrofti WUBG_07283 N 0.502
nAv.1.0.1.g03900 Acanthocheilonema viteae nAv.1.0.1.g03900 N 0.502
nDi.2.2.2.g02092 Dirofilaria immitis nDi.2.2.2.g02092 N 0.502
WBGene00245293 Onchocerca volvulus WBGene00245293 N 0.502
nOo.2.0.1.g01360 Onchocerca ochengi nOo.2.0.1.g01360 N 0.502
OFLC_0001285101 Onchocerca flexuosa OFLC_0001285101 N 0.502
TCLT_0000145301 Thelazia callipaeda TCLT_0000145301 N 0.502
Bm7076 Brugia malayi Bm7076 N 0.502
CapteG156119 Capitella teleta CapteG156119 N 0.485
ASIM_0001578601 Anisakis simplex ASIM_0001578601 N 0.483
CRE25200 Caenorhabditis remanei CRE25200 N 0.483
CBN09141 Caenorhabditis brenneri CBN09141 N 0.483
ASIM_0001639001 Anisakis simplex ASIM_0001639001 N 0.483
ASU_02248 Ascaris suum ASU_02248 N 0.477
ALUE_0000987201 Ascaris lumbricoides ALUE_0000987201 N 0.477
SMUV_0000644601 Syphacia muris SMUV_0000644601 N 0.477
Sakowv30017721m.g Saccoglossus kowalevskii Sakowv30017721m.g N 0.475
NEMVEDRAFT_v1g177453 Nematostella vectensis NEMVEDRAFT_v1g177453 N 0.474
NV11999 Nasonia vitripennis NV11999 N 0.463
LLOJ006040 Lutzomyia longipalpis LLOJ006040 N 0.462
AAH41216 Xenopus laevis AAH41216 N 0.462
Hsal_01302--XP_395543.3_APIME Harpegnathos saltator Hsal_01302--XP_395543.3_APIME N 0.461
LDEC003494 Leptinotarsa decemlineata LDEC003494 N 0.461
Cflo_00654--XP_395543.3_APIME Camponotus floridanus Cflo_00654--XP_395543.3_APIME N 0.461
HHAL002088-PA Halyomorpha halys HHAL002088-PA N 0.461
YQE_02381 Dendroctonus ponderosae YQE_02381 N 0.461
L798_00593 Zootermopsis nevadensis L798_00593 N 0.461
GB50847 Apis mellifera GB50847 N 0.461
DAPPUDRAFT_305068 Daphnia pulex DAPPUDRAFT_305068 N 0.461
ACEP21543 Atta cephalotes ACEP21543 N 0.461
TC007745 Tribolium castaneum TC007745 N 0.461
ISCW021016 Ixodes scapularis ISCW021016 N 0.459
LotgiG111061 Lottia gigantea LotgiG111061 N 0.458
ENSOCUG00000016848 Oryctolagus cuniculus ENSOCUG00000016848 N 0.456
HelroG188630 Helobdella robusta HelroG188630 N 0.456
Hba_20635 Heterorhabditis bacteriophora Hba_20635 N 0.455
ENSCJAG00000006608 Callithrix jacchus ENSCJAG00000006608 N 0.455
ENSXMAG00000002642 Xiphophorus maculatus ENSXMAG00000002642 N 0.454
ENSPFOG00000009890 Poecilia formosa ENSPFOG00000009890 N 0.454
ENSGMOG00000002045 Gadus morhua ENSGMOG00000002045 N 0.454
ENSONIG00000006293 Oreochromis niloticus ENSONIG00000006293 N 0.454
smarce1 Oryzias latipes ENSORLG00000018629 N 0.454
ENSPFOG00000019561 Poecilia formosa ENSPFOG00000019561 N 0.454
smarce1 Tetraodon nigroviridis ENSTNIG00000014009 N 0.454
smarce1 Takifugu rubripes ENSTRUG00000012899 N 0.454
PPAI002058 Phlebotomus papatasi PPAI002058 N 0.454
MCOS_0000928101 Mesocestoides corti MCOS_0000928101 N 0.452
AC123471.1 Rattus norvegicus ENSRNOG00000018377 N 0.452
CPIJ018416 Culex quinquefasciatus CPIJ018416 N 0.450
CPIJ007400 Culex quinquefasciatus CPIJ007400 N 0.450
ACYPI008028 Acyrthosiphon pisum ACYPI008028 N 0.450
CpipJ_CPIJ007400 Culex pipiens CpipJ_CPIJ007400 N 0.450
AAEL010903 Aedes aegypti AAEL010903 N 0.450
CpipJ_CPIJ018416 Culex pipiens CpipJ_CPIJ018416 N 0.450
SMARCE1 Gasterosteus aculeatus ENSGACG00000018114 N 0.450
CLEC009203 Cimex lectularius CLEC009203 N 0.448
CLEC001104 Cimex lectularius CLEC001104 N 0.448
HDID_0000207001 Hymenolepis diminuta HDID_0000207001 N 0.446
PXEA_0001727801 Protopolystoma xenopodis PXEA_0001727801 N 0.444
SSLN_0001888901 Schistocephalus solidus SSLN_0001888901 N 0.442
PPA02543 Pristionchus pacificus PPA02543 N 0.442
scaffold237-EXSNAP2012.36 Pristionchus exspectatus scaffold237-EXSNAP2012.36 N 0.442
SMAR004982 Strigamia maritima SMAR004982 N 0.441
HMEL010720 Heliconius melpomene HMEL010720 N 0.440
KGM_12870 Danaus plexippus KGM_12870 N 0.440
TASK_0000875901 Taenia asiatica TASK_0000875901 N 0.438
ECANG7_05376 Echinococcus canadensis ECANG7_05376 N 0.438
EmuJ_000113200 Echinococcus multilocularis EmuJ_000113200 N 0.438
TsM_000047400 Taenia solium TsM_000047400 N 0.438
T265_02983 Opisthorchis viverrini T265_02983 N 0.437
ENSCING00000007774 Ciona intestinalis ENSCING00000007774 N 0.437
HHAL007378-PA Halyomorpha halys HHAL007378-PA N 0.437
D915_15883 Fasciola hepatica D915_15883 N 0.437
SMU15005679 Schmidtea mediterranea SMU15005679 N 0.436
SMTD_0000014601 Schistosoma mattheei SMTD_0000014601 N 0.435
SROB_0000607501 Schistosoma rodhaini SROB_0000607501 N 0.435
SCUD_0000923501 Schistosoma curassoni SCUD_0000923501 N 0.435
A_05744 Schistosoma haematobium A_05744 N 0.435
Sjc_0000110 Schistosoma japonicum Sjc_0000110 N 0.435
Smp_154640 Schistosoma mansoni Smp_154640 N 0.435
SPU_009282 Strongylocentrotus purpuratus SPU_009282 N 0.434
csin103376 Clonorchis sinensis csin103376 N 0.430
GA26137 Drosophila pseudoobscura FBgn0247513 N 0.427
GL26801 Drosophila persimilis FBgn0164382 N 0.427
TriadG53566 Trichoplax adhaerens TriadG53566 N 0.427
ENSFCAG00000026463 Felis catus ENSFCAG00000026463 N 0.423
LCUP013669 Lucilia cuprina LCUP013669 N 0.422
L898_g375 Steinernema monticolum L898_g375 N 0.420
L596_g22461 Steinernema carpocapsae L596_g22461 N 0.419
L892_g30100 Steinernema scapterisci L892_g30100 N 0.419