stat5b (Danio rerio)
STAT

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF02864 (STAT_bind) IPR013801 ENSDARG00000055588 T337397_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in several processes, including cell surface receptor signaling pathway; defense response; and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of transcription, DNA-templated and signal transduction. Predicted to be located in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in growth hormone insensitivity syndrome with immune dysregulation 1 and growth hormone insensitivity syndrome with immune dysregulation 2. Orthologous to human STAT5A (signal transducer and activator of transcription 5A) and STAT5B (signal transducer and activator of transcription 5B). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Stat5b
M09421_2.00 		Mus musculus
NNTTCYMRGAAN
NTTCYKRGAANN		 Misc
Kulakovskiy et al.(2013)
STA5B_MOUSE.H11MO.0.A 		0.860 0.860
STAT5B
M09417_2.00 		Homo sapiens
NNTTCYMRGAAN
NTTCYKRGAANN		 Misc
Kulakovskiy et al.(2013)
STA5B_HUMAN.H11MO.0.A 		0.852 0.852
Stat5a
M09420_2.00 		Mus musculus
TTCYMRGAAN
NTTCYKRGAA		 Misc
Kulakovskiy et al.(2013)
STA5A_MOUSE.H11MO.0.A 		0.852 0.852
STAT5B
M11371_2.00 		Homo sapiens
NDWTTCYNGGAAWHN
NDWTTCCNRGAAWHN		 Transfac
Matys et al.(2006)
V$STAT5B_01 		0.832 0.832
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSDARP00000110501 STAT 332 583
ENSDARP00000112066 STAT 332 582
ENSDARP00000138608 STAT 332 582

Links

Other STAT family TFs
Other Danio rerio TFs

Invalid Input OrderBy

107 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action