| NCBI Gene Info:Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within hemopoiesis. Predicted to be located in cytoplasm and nucleus. Is expressed in cardiovascular system; intermediate cell mass of mesoderm; kidney; and lateral plate mesoderm. Human ortholog(s) of this gene implicated in breast cancer (multiple); immunodeficiency 31A; immunodeficiency 31B; immunodeficiency 31C; and prostate adenocarcinoma. Orthologous to human STAT1 (signal transducer and activator of transcription 1). [provided by Alliance of Genome Resources, Apr 2022] |