CIS-BP Database: Catalog of Inferred Sequence Binding Preferences - Update
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Stat5a
(
Rattus norvegicus
)
STAT
TF Information
Pfam ID
Interpro ID
Gene ID
CIS-BP ID
Sequence source
Animal TF db
PF02864 (STAT_bind)
IPR013801
ENSRNOG00000019496
T337653_2.00
Ensembl (2018-Dec-8)
Link out
NCBI Gene Info:
Enables DNA-binding transcription factor activity; double-stranded DNA binding activity; and sequence-specific DNA binding activity. Involved in several processes, including mammary gland development; receptor signaling pathway via JAK-STAT; and response to ethanol. Acts upstream of or within cellular response to cytokine stimulus and cellular response to organic cyclic compound. Located in cytoplasm and nucleus. Orthologous to human STAT5A (signal transducer and activator of transcription 5A). [provided by Alliance of Genome Resources, Apr 2022]
Directly determined binding motifs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
No direct experiments
Motifs from related TFs
Name/Motif ID
Species
Forward
Reverse
Type/Study/Study ID
SR
Score
DBD
Identity
Stat5a
M09420_2.00
Mus musculus
TTCYMRGAAN
NTTCYKRGAA
Misc
Kulakovskiy et al.(2013)
STA5A_MOUSE.H11MO.0.A
0.988
0.988
Stat5b
M09421_2.00
Mus musculus
NNTTCYMRGAAN
NTTCYKRGAANN
Misc
Kulakovskiy et al.(2013)
STA5B_MOUSE.H11MO.0.A
0.975
0.975
STAT5B
M09417_2.00
Homo sapiens
NNTTCYMRGAAN
NTTCYKRGAANN
Misc
Kulakovskiy et al.(2013)
STA5B_HUMAN.H11MO.0.A
0.967
0.967
STAT5B
M11371_2.00
Homo sapiens
NDWTTCYNGGAAWHN
NDWTTCCNRGAAWHN
Transfac
Matys et al.(2006)
V$STAT5B_01
0.967
0.967
For this family, TFs with SR scores >
0.700
will likely have a similar motif
DNA Binding Domains
Protein ID
Domain
From
To
Sequence
ENSRNOP00000026662
STAT
332
582
FIIEKQPPQVLKTQTKFAATVRLLVGGKLNVHMNPPQVKATIISEQQAKSLLKNENTRNDYSGEILNNCCVMEYHQATGTLSAHFRNMSLKRIKRADRRGAESVTEEKFTVLFESQFSVGSNELVFQVKTLSLPVVVIVHGSQDHNATATVLWDNAFAEPGRVPFAVPDKVLWPQLCEALNMKFKAEVQSNRGLTKENLVFLAQKLFNSSSNHLEDYNSMSVSWSQFNRENLPGWNYTFWQWFDGVMEVLK
Links
Other
STAT
family TFs
Other
Rattus norvegicus
TFs
104 Related TFs
Name
Species
Gene ID
Motif Evidence
SR
Score
Action
Invalid Input OrderBy