ENSP00000293328 (Macaca fascicularis)
STAT

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source
PF02864 (STAT_bind) IPR013801 ENSP00000293328 T337828_2.00 GigaDB (2015-Oct-22)
NCBI Gene Info:
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL. [provided by RefSeq, Jul 2008]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
STAT5B
M09417_2.00
Homo sapiens
NNTTCYMRGAAN

NTTCYKRGAANN
Misc
Kulakovskiy et al.(2013)
STA5B_HUMAN.H11MO.0.A
1.000 1.000
STAT5B
M11371_2.00
Homo sapiens
NDWTTCYNGGAAWHN

NDWTTCCNRGAAWHN
Transfac
Matys et al.(2006)
V$STAT5B_01
1.000 1.000
Stat5b
M09421_2.00
Mus musculus
NNTTCYMRGAAN

NTTCYKRGAANN
Misc
Kulakovskiy et al.(2013)
STA5B_MOUSE.H11MO.0.A
0.979 0.979
Stat5a
M09420_2.00
Mus musculus
TTCYMRGAAN

NTTCYKRGAA
Misc
Kulakovskiy et al.(2013)
STA5A_MOUSE.H11MO.0.A
0.959 0.959
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000293328 STAT 332 582

Links

Other STAT family TFs
Other Macaca fascicularis TFs

105 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
STAT5B Gorilla gorilla ENSGGOG00000008216 I 1.000
ENSNLEG00000011444 Nomascus leucogenys ENSNLEG00000011444 I 1.000
ENSCSAG00000003133 Chlorocebus sabaeus ENSCSAG00000003133 I 1.000
ENSPPYG00000008394 Pongo abelii ENSPPYG00000008394 I 1.000
STAT5B Pan troglodytes ENSPTRG00000009198 I 1.000
ENSPANG00000021460 Papio anubis ENSPANG00000021460 I 1.000
STAT5B Homo sapiens ENSG00000173757 D 1.000
ENSMPUG00000010528 Mustela putorius furo ENSMPUG00000010528 I 0.992
ENSFCAG00000028112 Felis catus ENSFCAG00000028112 I 0.992
ENSP00000293328-D1 Bos grunniens ENSP00000293328-D1 I 0.992
STAT5B Bos taurus ENSBTAG00000010125 I 0.992
STAT5B Equus caballus ENSECAG00000007847 I 0.988
STAT5B Canis familiaris ENSCAFG00000015509 I 0.988
STAT5B Sus scrofa ENSSSCG00000017406 I 0.988
ENSOARG00000018964 Ovis aries ENSOARG00000018964 I 0.988
ENSAMEG00000006061 Ailuropoda melanoleuca ENSAMEG00000006061 I 0.988
STAT5B Tursiops truncatus ENSTTRG00000006684 I 0.984
STAT5B Ochotona princeps ENSOPRG00000008312 I 0.984
ENSSTOG00000006691 Ictidomys tridecemlineatus ENSSTOG00000006691 I 0.984
Stat5b Rattus norvegicus ENSRNOG00000019075 I 0.979
STAT5B Loxodonta africana ENSLAFG00000014045 I 0.979
STAT5B Myotis lucifugus ENSMLUG00000012050 I 0.979
Myotis_brandtii_STAT5B_10015330 Myotis brandtii Myotis_brandtii_STAT5B_10015330 I 0.979
Stat5b Mus musculus ENSMUSG00000020919 D 0.979
STAT5A Macaca mulatta ENSMMUG00000010705 I 0.975
ENSPANG00000021452 Papio anubis ENSPANG00000021452 I 0.975
ENSCSAG00000003196 Chlorocebus sabaeus ENSCSAG00000003196 I 0.975
ENSFCAG00000002153 Felis catus ENSFCAG00000002153 I 0.975
STAT5B Oryctolagus cuniculus ENSOCUG00000005078 I 0.975
STAT5A Pan troglodytes ENSPTRG00000009199 I 0.975
STAT5A Homo sapiens ENSG00000126561 D 0.975
ENSPPYG00000008393 Pongo abelii ENSPPYG00000008393 I 0.975
ENSSARG00000014205 Sorex araneus ENSSARG00000014205 I 0.971
ENSOARG00000000809 Ovis aries ENSOARG00000000809 I 0.970
STAT5A Echinops telfairi ENSETEG00000008535 I 0.968
Stat5a Rattus norvegicus ENSRNOG00000019496 I 0.967
ENSBTAP00000034715-D1 Bos grunniens ENSBTAP00000034715-D1 I 0.967
STAT5A Bos taurus ENSBTAG00000009496 I 0.967
ENSMODG00000014836 Monodelphis domestica ENSMODG00000014836 I 0.967
ENSSHAG00000003879 Sarcophilus harrisii ENSSHAG00000003879 I 0.967
ENSNLEG00000027072 Nomascus leucogenys ENSNLEG00000027072 I 0.965
ENSMPUG00000010517 Mustela putorius furo ENSMPUG00000010517 I 0.963
STAT5A Sus scrofa ENSSSCG00000017402 I 0.963
ENSAMEG00000006086 Ailuropoda melanoleuca ENSAMEG00000006086 I 0.963
STAT5A Erinaceus europaeus ENSEEUG00000003642 I 0.963
STAT5A Tursiops truncatus ENSTTRG00000007155 I 0.963
ENSP00000400320 Macaca fascicularis ENSP00000400320 I 0.962
STAT5A Oryctolagus cuniculus ENSOCUG00000023066 I 0.959
STAT5A Canis familiaris ENSCAFG00000015346 I 0.959
STAT5A Myotis lucifugus ENSMLUG00000026308 I 0.959
Stat5a Mus musculus ENSMUSG00000004043 D 0.959
Stat5a Dipodomys ordii ENSDORG00000000303 I 0.959
Alligator_sinensis_CCG021131.1 Alligator sinensis Alligator_sinensis_CCG021131.1 I 0.959
ENSSTOG00000006713 Ictidomys tridecemlineatus ENSSTOG00000006713 I 0.959
ENSCPOG00000026466 Cavia porcellus ENSCPOG00000026466 I 0.959
STAT5A Equus caballus ENSECAG00000012328 I 0.955
STAT5A Procavia capensis ENSPCAG00000010107 I 0.955
Gfo_R009045 Geospiza fortis Gfo_R009045 I 0.955
Afo_R011286 Aptenodytes forsteri Afo_R011286 I 0.955
ENSTGUG00000002572 Taeniopygia guttata ENSTGUG00000002572 I 0.955
STAT5A Loxodonta africana ENSLAFG00000014055 I 0.955
STAT5A Otolemur garnettii ENSOGAG00000001513 I 0.955
ENSMEUG00000006640 Macropus eugenii ENSMEUG00000006640 I 0.955
STAT5A Pteropus vampyrus ENSPVAG00000003881 I 0.951
ENSOANG00000006496 Ornithorhynchus anatinus ENSOANG00000006496 I 0.951
ENSFALG00000000667 Ficedula albicollis ENSFALG00000000667 I 0.951
Aan_R006195 Calypte anna Aan_R006195 I 0.947
STAT5B Gallus gallus ENSGALG00000003282 I 0.947
ENSMGAG00000003430 Meleagris gallopavo ENSMGAG00000003430 I 0.942
Myotis_brandtii_STAT5A_10015329 Myotis brandtii Myotis_brandtii_STAT5A_10015329 I 0.931
Ogr09155 Ophisaurus gracilis Ogr09155 I 0.930
ENSMODG00000014816 Monodelphis domestica ENSMODG00000014816 I 0.930
Pvit_13934 Pogona vitticeps Pvit_13934 I 0.930
STAT5B Echinops telfairi ENSETEG00000008528 I 0.927
ENSACAG00000017951 Anolis carolinensis ENSACAG00000017951 I 0.926
stat5b Xenopus tropicalis XB-GENE-5913743 I 0.926
stat5b.S Xenopus laevis XB-GENE-5913744 I 0.926
stat5b.L Xenopus laevis XB-GENE-17341802 I 0.926
STAT5A Cavia porcellus ENSCPOG00000012203 I 0.909
ENSLOCG00000012527 Lepisosteus oculatus ENSLOCG00000012527 I 0.905
ENSONIG00000001131 Oreochromis niloticus ENSONIG00000001131 I 0.897
stat5a Oryzias latipes ENSORLG00000003961 I 0.897
stat5a Gasterosteus aculeatus ENSGACG00000008634 I 0.893
ENSXMAG00000005165 Xiphophorus maculatus ENSXMAG00000005165 I 0.893
ENSLACG00000002646 Latimeria chalumnae ENSLACG00000002646 I 0.893
stat5a Danio rerio ENSDARG00000019392 I 0.893
ENSPFOG00000012581 Poecilia formosa ENSPFOG00000012581 I 0.889
stat5a Tetraodon nigroviridis ENSTNIG00000011707 I 0.881
STAT5B Otolemur garnettii ENSOGAG00000017198 I 0.872
stat5a Takifugu rubripes ENSTRUG00000015454 I 0.868
ENSGMOG00000014154 Gadus morhua ENSGMOG00000014154 I 0.864
ENSPFOG00000010905 Poecilia formosa ENSPFOG00000010905 I 0.864
STAT5A Ochotona princeps ENSOPRG00000008335 I 0.860
stat5b Danio rerio ENSDARG00000055588 I 0.852
STAT5B Microcebus murinus ENSMICG00000011988 I 0.848
stat5b Oryzias latipes ENSORLG00000014335 I 0.844
ENSPMAG00000009008 Petromyzon marinus ENSPMAG00000009008 I 0.840
stat5b Gasterosteus aculeatus ENSGACG00000015405 I 0.831
ENSGMOG00000015001 Gadus morhua ENSGMOG00000015001 I 0.802
SNAPOd2T00000256001 Oikopleura dioica SNAPOd2T00000256001 I 0.795
STAT5A Gorilla gorilla ENSGGOG00000017103 I 0.773
ENSOANG00000004051 Ornithorhynchus anatinus ENSOANG00000004051 I 0.746
ENSAMXG00000013978 Astyanax mexicanus ENSAMXG00000013978 I 0.744
STAT5B Pteropus vampyrus ENSPVAG00000003876 I 0.719
ENSAMXG00000000480 Astyanax mexicanus ENSAMXG00000000480 I 0.719