TBR1 (Homo sapiens)
T-box

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00907 (T-box) IPR001699 ENSG00000136535 T339893_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
TBR1
M03560_2.00
Homo sapiens
AGGTGTGAAN

NTTCACACCT
SELEX
Jolma et al.(2013)
TBR1_1
(Direct) (Direct)
TBR1
M03561_2.00
Homo sapiens
RAGGTGTGAAH

DTTCACACCTY
SELEX
Jolma et al.(2013)
TBR1_2
(Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
Tbr1
M01028_2.00
Mus musculus
DTVRCAMNYH

DRNKTGYBAH
PBM
SebePedros et al.(2013)
pTH2659
0.530 1.000
Eomes
M00215_2.00
Mus musculus
RDGTGYBANN

NNTVRCACHY
PBM
Badis et al.(2009)
Eomes_0921
0.865 0.874
EOMES
M03563_2.00
Homo sapiens
DAGGTGTGAWNNN

NNNWTCACACCTH
SELEX
Jolma et al.(2013)
EOMES_1
0.865 0.869
EOMES
M03564_2.00
Homo sapiens
TVACACNTNNNDRNGTGTGA

TCACACNYHNNNANGTGTBA
SELEX
Jolma et al.(2013)
EOMES_2
0.865 0.869
EOMES
M02752_2.00
Homo sapiens
AGGTGTGAW

WTCACACCT
SELEX
Jolma et al.(2010)
EOMES_monomer
0.865 0.869
EOMES
M05807_2.00
Homo sapiens
DAGGTGTGAN

NTCACACCTH
SELEX
Yin et al.(2017)
EOMES_eDBD_HT-SELEX
0.865 0.869
EOMES
M09647_2.00
Homo sapiens
ARGTGWKAAN

NTTMWCACYT
Misc
Heinz et al.(2010)
H9-Eomes_GSE26097
0.865 0.869
EOMES
M05808_2.00
Homo sapiens
NABGTGYKAH

DTMRCACVTN
SELEX
Yin et al.(2017)
EOMES_eDBD_Methyl-HT-SELEX
0.865 0.869
A0A075Q982_PATMI
M00734_2.00
Patiria miniata
NAGGTGTBAN

NTVACACCTN
PBM
Cheatle-Jarvela et al.(2014)
PmTbr
0.789 0.645
TBX21
M03546_2.00
Homo sapiens
GGTGTGAHDTMACACY

RGTGTKAHDTCACACC
SELEX
Jolma et al.(2013)
TBX21_1
0.766 0.732
TBX21
M03547_2.00
Homo sapiens
DAGGTGTGAW

WTCACACCTH
SELEX
Jolma et al.(2013)
TBX21_2
0.766 0.732
TBX21
M03548_2.00
Homo sapiens
TMACACYTNNDAGGTGTGA

TCACACCTHNNARGTGTKA
SELEX
Jolma et al.(2013)
TBX21_3
0.766 0.732
TBX21
M03549_2.00
Homo sapiens
GGTGTGAWATCACACC

GGTGTGATWTCACACC
SELEX
Jolma et al.(2013)
TBX21_4
0.766 0.732
TBX21
M03550_2.00
Homo sapiens
DAGGTGTGAW

WTCACACCTH
SELEX
Jolma et al.(2013)
TBX21_5
0.766 0.732
TBX21
M03551_2.00
Homo sapiens
TSACACCWNMRAGGTGTGA

TCACACCTYKNWGGTGTSA
SELEX
Jolma et al.(2013)
TBX21_6
0.766 0.732
TBX21
M05793_2.00
Homo sapiens
DAGGTGTKAN

NTMACACCTH
SELEX
Yin et al.(2017)
TBX21_eDBD_HT-SELEX
0.766 0.732
TBX21
M09425_2.00
Homo sapiens
NDSDRGSTGWBRN

NYVWCASCYHSHN
Misc
Kulakovskiy et al.(2013)
TBX21_HUMAN.H11MO.0.A
0.766 0.732
Tbx21
M09428_2.00
Mus musculus
DNDDSTGWSDND

HNHSWCASHHNH
Misc
Kulakovskiy et al.(2013)
TBX21_MOUSE.H11MO.0.A
0.766 0.732
Tbx21
M09648_2.00
Mus musculus
ADGTGWSAHN

NDTSWCACHT
Misc
Heinz et al.(2010)
CD8-Tbet_GSE33802
0.766 0.732
TBX21
M05794_2.00
Homo sapiens
DASGTGTKAW

WTMACACSTH
SELEX
Yin et al.(2017)
TBX21_eDBD_Methyl-HT-SELEX
0.766 0.732
SPU_025584
M00733_2.00
Strongylocentrotus purpuratus
RGGTGTGANN

NNTCACACCY
PBM
Cheatle-Jarvela et al.(2014)
SpTbr
0.762 0.617
For this family, TFs with SR scores > 0.734 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000374205 T-box 206 393
ENSP00000387023 T-box 1 106
ENSP00000393934 T-box 1 128

Links

Other T-box family TFs
Other Homo sapiens TFs

219 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
nAv.1.0.1.g04749 Acanthocheilonema viteae nAv.1.0.1.g04749 I 0.000
ANCCAN_24706 Ancylostoma caninum ANCCAN_24706 I 0.000
ANCCAN_23624 Ancylostoma caninum ANCCAN_23624 I 0.000
ANCCEY_02877 Ancylostoma ceylanicum ANCCEY_02877 I 0.000
ANCDUO_15205 Ancylostoma duodenale ANCDUO_15205 I 0.000
ACOC_0000703501 Angiostrongylus costaricensis ACOC_0000703501 I 0.000
AALB003340 Anopheles albimanus AALB003340 I 0.000
AARA009757 Anopheles arabiensis AARA009757 I 0.000
ACHR007729 Anopheles christyi ACHR007729 I 0.000
ACUA003826 Anopheles culicifacies ACUA003826 I 0.000
ADIR006616 Anopheles dirus ADIR006616 I 0.000
AEPI001687 Anopheles epiroticus AEPI001687 I 0.000
AMAM006295 Anopheles maculatus AMAM006295 I 0.000
AMIN002618 Anopheles minimus AMIN002618 I 0.000
ASTEI07078 Anopheles stephensi ASTEI07078 I 0.000
BGIBMGA005084 Bombyx mori BGIBMGA005084 I 0.000
Bm5024 Brugia malayi Bm5024 I 0.000
Cflo_00868--XP_392355.3_APIME Camponotus floridanus Cflo_00868--XP_392355.3_APIME I 0.000
CpipJ_CPIJ004052 Culex pipiens CpipJ_CPIJ004052 I 0.000
CPIJ004052 Culex quinquefasciatus CPIJ004052 I 0.000
CGOC_0000822101 Cylicostephanus goldi CGOC_0000822101 I 0.000
YQE_10516 Dendroctonus ponderosae YQE_10516 I 0.000
DICVIV_00921 Dictyocaulus viviparus DICVIV_00921 I 0.000
GL11998 Drosophila persimilis FBgn0149606 I 0.000
EEL_0000266401 Elaeophora elaphi EEL_0000266401 I 0.000
EVEC_0001110501 Enterobius vermicularis EVEC_0001110501 I 0.000
HCOI02128500 Haemonchus contortus HCOI02128500 I 0.000
nLs.2.1.2.g05095 Litomosoides sigmodontis nLs.2.1.2.g05095 I 0.000
LOAG_14553 Loa loa LOAG_14553 I 0.000
LCUP011134 Lucilia cuprina LCUP011134 I 0.000
ENSMEUG00000002316 Macropus eugenii ENSMEUG00000002316 I 0.000
MCOS_0000195601 Mesocestoides corti MCOS_0000195601 I 0.000
NECAME_07738 Necator americanus NECAME_07738 I 0.000
nOo.2.0.1.g10265 Onchocerca ochengi nOo.2.0.1.g10265 I 0.000
T265_07444 Opisthorchis viverrini T265_07444 N 0.000
PPAI010076 Phlebotomus papatasi PPAI010076 I 0.000
PXEA_0002638601 Protopolystoma xenopodis PXEA_0002638601 I 0.000
A_05794 Schistosoma haematobium A_05794 I 0.000
Sjc_0122310 Schistosoma japonicum Sjc_0122310 I 0.000
SMTD_0001301801 Schistosoma mattheei SMTD_0001301801 I 0.000
SBAD_0000068201 Soboliphyme baturini SBAD_0000068201 I 0.000
SINV18378 Solenopsis invicta SINV18378 I 0.000
SVUK_0000405601 Strongylus vulgaris SVUK_0000405601 I 0.000
TELCIR_21732 Teladorsagia circumcincta TELCIR_21732 I 0.000
TELCIR_22329 Teladorsagia circumcincta TELCIR_22329 I 0.000
D917_07791 Trichinella nativa D917_07791 I 0.000
D918_02805 Trichuris suis D918_02805 I 0.000
WUBG_06449 Wuchereria bancrofti WUBG_06449 I 0.000