Tbx19 (Mus musculus)
T-box

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00907 (T-box) IPR001699 ENSMUSG00000026572 T340143_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
This gene encodes a member of a family of transcription factors containing a characteristic T-box DNA-binding domain. The encoded protein promotes expression of the pro-opiomelanocortin (POMC) gene, which is important for the differentiation of cells in the pituitary gland. [provided by RefSeq, Mar 2013]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
TBX19
M03562_2.00
Homo sapiens
NDTVRCACVTANGTGYKANN

NNTMRCACNTABGTGYBAHN
SELEX
Jolma et al.(2013)
TBX19_1
0.912 0.983
TBX19
M05803_2.00
Homo sapiens
NAGGTGYBAHWDTMRCACNTN

NANGTGYKAHWDTVRCACCTN
SELEX
Yin et al.(2017)
TBX19_eDBD_HT-SELEX
0.912 0.983
TBX19
M05804_2.00
Homo sapiens
NANGTGYKAHWDTVRCACSTN

NASGTGYBAHWDTMRCACNTN
SELEX
Yin et al.(2017)
TBX19_eDBD_Methyl-HT-SELEX
0.912 0.983
T
M05809_2.00
Homo sapiens
NANGTGYGAHWWNTVRCACCTN

NAGGTGYBANWWDTCRCACNTN
SELEX
Yin et al.(2017)
T_eDBD_HT-SELEX_1
0.868 0.835
T
M05810_2.00
Homo sapiens
DTCRCAYVTABGTGYGAH

DTCRCACVTABRTGYGAH
SELEX
Yin et al.(2017)
T_eDBD_HT-SELEX_2
0.868 0.835
T
M09427_2.00
Homo sapiens
BYNVCANNNVDGTGWKARDN

NHYTMWCACHBNNNTGBNRV
Misc
Kulakovskiy et al.(2013)
BRAC_HUMAN.H11MO.0.A
0.868 0.835
T
M09431_2.00
Mus musculus
VVNRAWTTSACASNYHDVTGBNMAN

NTKNVCABHDRNSTGTSAAWTYNBB
Misc
Kulakovskiy et al.(2013)
BRAC_MOUSE.H11MO.0.B
0.868 0.835
T
M09651_2.00
Mus musculus
NYTVDCASNNNNSTGHBARNN

NNYTVDCASNNNNSTGHBARN
Misc
Heinz et al.(2010)
Mesoendoderm-Brachyury_GSE54963
0.868 0.835
T
M11384_2.00
Homo sapiens
MKHBTSACACSTAGGTGTGAAATK

MATTTCACACCTASGTGTSAVDMK
Transfac
Matys et al.(2006)
V$BRACH_01
0.868 0.835
T
M05811_2.00
Homo sapiens
NABGTGYGAHWWNTVRCACSTN

NASGTGYBANWWDTCRCACVTN
SELEX
Yin et al.(2017)
T_eDBD_Methyl-HT-SELEX_1
0.868 0.835
T
M05812_2.00
Homo sapiens
DTMRCAYVTABGTGYKAH

DTMRCACVTABRTGYKAH
SELEX
Yin et al.(2017)
T_eDBD_Methyl-HT-SELEX_2
0.868 0.835
byn
M03984_2.00
Drosophila melanogaster
ABGTGYGADDD

HHHTCRCACVT
SELEX
Nitta et al.(2015)
byn_1
0.816 0.756
byn
M03985_2.00
Drosophila melanogaster
DNGTGYBAHWWDTVRCACNH

DNGTGYBAHWWDTVRCACNH
SELEX
Nitta et al.(2015)
byn_2
0.816 0.756
byn
M03986_2.00
Drosophila melanogaster
RDGTGYGADNDNDNNNNNNDRDGTGYGADD

HHTCRCACHYHNNNNNNHNHNHTCRCACHY
SELEX
Nitta et al.(2015)
byn_3
0.816 0.756
byn
M03987_2.00
Drosophila melanogaster
NNTMRCAYNWWNRTGYKAHN

NDTMRCAYNWWNRTGYKANN
SELEX
Nitta et al.(2015)
byn_4
0.816 0.756
byn
M06453_2.00
Drosophila melanogaster
ADGTGCDA

THGCACHT
B1H
Zhu et al.(2011)
byn_FlyReg_FBgn0011723
0.816 0.756
For this family, TFs with SR scores > 0.734 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSMUSP00000027859 T-box 41 216
ENSMUSP00000123909 T-box 1 151

Links

Other T-box family TFs
Other Mus musculus TFs

179 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
AAEL011926 Aedes aegypti AAEL011926 I 0.799
ENSAMEG00000009278 Ailuropoda melanoleuca ENSAMEG00000009278 I 0.767
ENSAMEG00000004326 Ailuropoda melanoleuca ENSAMEG00000004326 I 0.917
Alligator_sinensis_CCG010779.1 Alligator sinensis Alligator_sinensis_CCG010779.1 I 0.889
Alligator_sinensis_CCG010961.2 Alligator sinensis Alligator_sinensis_CCG010961.2 I 0.799
Alligator_sinensis_CCG019781.1 Alligator sinensis Alligator_sinensis_CCG019781.1 I 0.846
ENSAPLG00000010506 Anas platyrhynchos ENSAPLG00000010506 I 0.889
T Anolis carolinensis ENSACAG00000003467 I 0.873
TBX19 Anolis carolinensis ENSACAG00000010693 I 0.889
AALB003755 Anopheles albimanus AALB003755 I 0.799
AARA000721 Anopheles arabiensis AARA000721 I 0.799
ACOM032190 Anopheles coluzzii ACOM032190 I 0.799
ACUA027826 Anopheles culicifacies ACUA027826 I 0.799
ADAC000433 Anopheles darlingi ADAC000433 I 0.799
ADIR001942 Anopheles dirus ADIR001942 I 0.799
AEPI011219 Anopheles epiroticus AEPI011219 I 0.799
AFUN010277 Anopheles funestus AFUN010277 I 0.799
AGAP011927 Anopheles gambiae AGAP011927 I 0.799
AMEC020399 Anopheles melas AMEC020399 I 0.798
AMIN008605 Anopheles minimus AMIN008605 I 0.799
AQUA010101 Anopheles quadriannulatus AQUA010101 I 0.799
ASIS006984 Anopheles sinensis ASIS006984 I 0.799
ASTEI05115 Anopheles stephensi ASTEI05115 I 0.799
GB51013 Apis mellifera GB51013 I 0.765
Afo_R013116 Aptenodytes forsteri Afo_R013116 I 0.889
ENSAMXG00000013638 Astyanax mexicanus ENSAMXG00000013638 I 0.796
ENSAMXG00000003991 Astyanax mexicanus ENSAMXG00000003991 I 0.808
BGIBMGA000322 Bombyx mori BGIBMGA000322 I 0.826
ENSP00000356795-D1 Bos grunniens ENSP00000356795-D1 I 0.911
T Bos taurus ENSBTAG00000018681 I 0.868
TBX19 Bos taurus ENSBTAG00000002952 I 0.911
estExt_gwp.C_9340008 Branchiostoma floridae estExt_gwp.C_9340008 I 0.830
estExt_GenewiseH_1.C_9340011 Branchiostoma floridae estExt_GenewiseH_1.C_9340011 I 0.831
estExt_gwp.C_650221 Branchiostoma floridae estExt_gwp.C_650221 I 0.831
estExt_fgenesh2_pg.C_650149 Branchiostoma floridae estExt_fgenesh2_pg.C_650149 I 0.830
Brh_R012030 Buceros rhinoceros Brh_R012030 I 0.889
TBX19 Callithrix jacchus ENSCJAG00000016812 I 0.920
T Callithrix jacchus ENSCJAG00000012508 I 0.868
Aan_R012309 Calypte anna Aan_R012309 I 0.896
Cflo_04209--XP_396427.2_APIME Camponotus floridanus Cflo_04209--XP_396427.2_APIME I 0.816
TBX19 Canis familiaris ENSCAFG00000015268 I 0.920
T Canis familiaris ENSCAFG00000000807 I 0.873
TBX19 Cavia porcellus ENSCPOG00000012456 I 0.920
T Cavia porcellus ENSCPOG00000001358 I 0.868
Cmyd_10020966 Chelonia mydas Cmyd_10020966 I 0.891
Cmyd_10017804 Chelonia mydas Cmyd_10017804 I 0.868
ENSCSAG00000011055 Chlorocebus sabaeus ENSCSAG00000011055 I 0.912
ENSCSAG00000012200 Chlorocebus sabaeus ENSCSAG00000012200 I 0.868
TBX19 Choloepus hoffmanni ENSCHOG00000010387 I 0.900
CLEC002870 Cimex lectularius CLEC002870 I 0.823
brachyury Ciona intestinalis ENSCING00000000810 I 0.778
ENSCSAVG00000002247 Ciona savignyi ENSCSAVG00000002247 I 0.783
CGI_10018059 Crassostrea gigas CGI_10018059 I 0.801
CpipJ_CPIJ011372 Culex pipiens CpipJ_CPIJ011372 I 0.802
CPIJ011372 Culex quinquefasciatus CPIJ011372 I 0.802
tbx19 Danio rerio ENSDARG00000079187 I 0.816
ta Danio rerio ENSDARG00000101576 I 0.799
tb Danio rerio ENSDARG00000039806 I 0.839
DAPPUDRAFT_44582 Daphnia pulex DAPPUDRAFT_44582 I 0.757
ENSDNOG00000016178 Dasypus novemcinctus ENSDNOG00000016178 I 0.868
TBX19 Dasypus novemcinctus ENSDNOG00000015810 I 0.883
Tbx19 Dipodomys ordii ENSDORG00000014860 I 0.896
GF25302 Drosophila ananassae FBgn0102294 I 0.816
GG15542 Drosophila erecta FBgn0107790 I 0.816
GH14805 Drosophila grimshawi FBgn0122281 I 0.816
byn Drosophila melanogaster FBgn0011723 D 0.816
GI11508 Drosophila mojavensis FBgn0134268 I 0.816
GL25108 Drosophila persimilis FBgn0162695 I 0.816
GA20217 Drosophila pseudoobscura FBgn0080212 I 0.816
GM25308 Drosophila sechellia FBgn0180168 I 0.816
GD14339 Drosophila simulans FBgn0186024 I 0.816
GJ13700 Drosophila virilis FBgn0200921 I 0.816
GK25266 Drosophila willistoni FBgn0227225 I 0.816
GE21864 Drosophila yakuba FBgn0239106 I 0.816
TBX19 Equus caballus ENSECAG00000010186 I 0.912
T Equus caballus ENSECAG00000007994 I 0.868
TBX19 Felis catus ENSFCAG00000015047 I 0.920
ENSFALG00000005706 Ficedula albicollis ENSFALG00000005706 I 0.889
ENSGMOG00000018941 Gadus morhua ENSGMOG00000018941 I 0.799
ENSGMOG00000017391 Gadus morhua ENSGMOG00000017391 I 0.815
TBX19 Gallus gallus ENSGALG00000015244 I 0.898
T Gallus gallus ENSGALG00000011489 I 0.873
tb Gasterosteus aculeatus ENSGACG00000005258 I 0.798
ta Gasterosteus aculeatus ENSGACG00000007637 I 0.799
Gfo_R011100 Geospiza fortis Gfo_R011100 N 0.798
Gfo_R000170 Geospiza fortis Gfo_R000170 I 0.889
T Gorilla gorilla ENSGGOG00000007693 I 0.868
TBX19 Gorilla gorilla ENSGGOG00000001338 I 0.912
Hsal_03707--XP_396427.2_APIME Harpegnathos saltator Hsal_03707--XP_396427.2_APIME I 0.816
T Homo sapiens ENSG00000164458 D 0.868
TBX19 Homo sapiens ENSG00000143178 D 0.912
XP_002164912.1 Hydra magnipapillata XP_002164912.1 I 0.810
XP_002154016.1 Hydra magnipapillata XP_002154016.1 I 0.747
ENSSTOG00000019913 Ictidomys tridecemlineatus ENSSTOG00000019913 I 0.912
ENSSTOG00000028238 Ictidomys tridecemlineatus ENSSTOG00000028238 I 0.868
ENSLACG00000011042 Latimeria chalumnae ENSLACG00000011042 I 0.812
ENSLACG00000015449 Latimeria chalumnae ENSLACG00000015449 I 0.842
ENSLOCG00000003838 Lepisosteus oculatus ENSLOCG00000003838 I 0.796
ENSLOCG00000016526 Lepisosteus oculatus ENSLOCG00000016526 I 0.842
ENSLOCG00000010586 Lepisosteus oculatus ENSLOCG00000010586 I 0.844
LotgiG154800 Lottia gigantea LotgiG154800 I 0.813
TBX19 Loxodonta africana ENSLAFG00000011227 I 0.913
T Loxodonta africana ENSLAFG00000012505 I 0.868
LCUP008716 Lucilia cuprina LCUP008716 I 0.816
ENSP00000356795 Macaca fascicularis ENSP00000356795 I 0.912
ENSMMUP00000022430 Macaca fascicularis ENSMMUP00000022430 I 0.868
SFT2D2 Macaca mulatta ENSMMUG00000005283 I 0.912
T Macaca mulatta ENSMMUG00000017047 I 0.868
T Meleagris gallopavo ENSMGAG00000012328 N 0.744
MCINX002868 Melitaea cinxia MCINX002868 I 0.826
TBX19 Microcebus murinus ENSMICG00000007817 I 0.912
ML174736a Mnemiopsis leidyi ML174736a I 0.801
TBX19 Monodelphis domestica ENSMODG00000002921 I 0.888
T Monodelphis domestica ENSMODG00000006318 I 0.868
MDOA012486 Musca domestica MDOA012486 I 0.816
ENSMPUG00000000522 Mustela putorius furo ENSMPUG00000000522 I 0.912
T Mus musculus ENSMUSG00000062327 D 0.868
Myotis_brandtii_TBX19_10024384 Myotis brandtii Myotis_brandtii_TBX19_10024384 I 0.920
TBX19 Myotis lucifugus ENSMLUG00000011933 I 0.920
NV14821 Nasonia vitripennis NV14821 I 0.816
ENSNLEG00000011552 Nomascus leucogenys ENSNLEG00000011552 I 0.868
ENSNLEG00000014917 Nomascus leucogenys ENSNLEG00000014917 I 0.912
T Ochotona princeps ENSOPRG00000003376 I 0.867
TBX19 Ochotona princeps ENSOPRG00000016564 I 0.915
SNAPOd2T00000418001 Oikopleura dioica SNAPOd2T00000418001 I 0.762
Ogr19099 Ophisaurus gracilis Ogr19099 I 0.873
ENSONIG00000007611 Oreochromis niloticus ENSONIG00000007611 I 0.799
ENSONIG00000008985 Oreochromis niloticus ENSONIG00000008985 I 0.817
ENSONIG00000009906 Oreochromis niloticus ENSONIG00000009906 I 0.842
T Ornithorhynchus anatinus ENSOANG00000012289 I 0.873
T Oryctolagus cuniculus ENSOCUG00000000660 I 0.828
TBX19 Oryctolagus cuniculus ENSOCUG00000014555 I 0.920
tb Oryzias latipes ENSORLG00000011262 I 0.840
me-t Oryzias latipes ENSORLG00000014067 I 0.799
T Otolemur garnettii ENSOGAG00000007863 I 0.868
TBX19 Otolemur garnettii ENSOGAG00000004458 I 0.920
ENSOARG00000012617 Ovis aries ENSOARG00000012617 I 0.911
ENSOARG00000004863 Ovis aries ENSOARG00000004863 I 0.868
TBX19 Pan troglodytes ENSPTRG00000001647 I 0.912
T Pan troglodytes ENSPTRG00000018789 I 0.868
ENSPANG00000005068 Papio anubis ENSPANG00000005068 I 0.868
PHUM392580 Pediculus humanus PHUM392580 I 0.821
ENSPSIG00000015509 Pelodiscus sinensis ENSPSIG00000015509 I 0.882
ENSPSIG00000005649 Pelodiscus sinensis ENSPSIG00000005649 I 0.868
ENSPFOG00000002451 Poecilia formosa ENSPFOG00000002451 I 0.799
ENSPFOG00000016071 Poecilia formosa ENSPFOG00000016071 I 0.833
ENSPFOG00000006034 Poecilia formosa ENSPFOG00000006034 I 0.792
Pvit_02210 Pogona vitticeps Pvit_02210 I 0.882
Pvit_04554 Pogona vitticeps Pvit_04554 I 0.873
ENSPPYG00000017163 Pongo abelii ENSPPYG00000017163 I 0.868
T Rattus norvegicus ENSRNOG00000012229 I 0.868
RPRC001186 Rhodnius prolixus RPRC001186 I 0.823
Sakowv30011577m.g Saccoglossus kowalevskii Sakowv30011577m.g I 0.785
ENSSHAG00000018940 Sarcophilus harrisii ENSSHAG00000018940 I 0.910
ENSSHAG00000018904 Sarcophilus harrisii ENSSHAG00000018904 I 0.868
SMAR005933 Strigamia maritima SMAR005933 I 0.747
TBX19 Sus scrofa ENSSSCG00000006299 I 0.920
T Taeniopygia guttata ENSTGUG00000009448 I 0.873
TBX19 Taeniopygia guttata ENSTGUG00000013434 I 0.889
tb Takifugu rubripes ENSTRUG00000011958 I 0.820
ta Takifugu rubripes ENSTRUG00000012130 I 0.796
tbx19 Takifugu rubripes ENSTRUG00000005718 I 0.812
tbx19 Tetraodon nigroviridis ENSTNIG00000006586 I 0.817
tb Tetraodon nigroviridis ENSTNIG00000016613 I 0.821
ta Tetraodon nigroviridis ENSTNIG00000005634 I 0.789
TC014076 Tribolium castaneum TC014076 I 0.813
TriadG25521 Trichoplax adhaerens TriadG25521 I 0.845
T Tursiops truncatus ENSTTRG00000016665 I 0.868
TBX19 Vicugna pacos ENSVPAG00000000446 I 0.920
tbxt.L Xenopus laevis XB-GENE-6255736 I 0.844
1XBR_A Xenopus laevis 1XBR_A I 0.842
1XBR_B Xenopus laevis 1XBR_B I 0.842
t2.S Xenopus laevis XB-GENE-5981788 I 0.848
tbxt.S Xenopus laevis XB-GENE-865212 I 0.842
tbxt Xenopus tropicalis XB-GENE-478789 I 0.844
t2 Xenopus tropicalis XB-GENE-5981736 I 0.874
ENSXMAG00000006226 Xiphophorus maculatus ENSXMAG00000006226 I 0.791
ENSXMAG00000011123 Xiphophorus maculatus ENSXMAG00000011123 I 0.842
ENSXMAG00000012033 Xiphophorus maculatus ENSXMAG00000012033 I 0.799