Tbx10 (Mus musculus)
T-box

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00907 (T-box) IPR001699 ENSMUSG00000037477 T340151_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in cell fate specification and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is expressed in several structures, including ear; genitourinary system; head surface ectoderm; hindbrain; and lung mesenchyme. Orthologous to human TBX10 (T-box transcription factor 10). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Tbx1
M00832_2.00 		Mus musculus
NRGTGTGAANN
NNTTCACACYN		 PBM
Weirauch et al.(2013)
pTH3822 		0.858 0.885
TBX1
M03570_2.00 		Homo sapiens
ARGTGTKAAAWHARGTGTGA
TCACACYTDWTTTMACACYT		 SELEX
Jolma et al.(2013)
TBX1_1 		0.858 0.885
TBX1
M03571_2.00 		Homo sapiens
AGGTGTGAWWTTCACACCT
AGGTGTGAAWWTCACACCT		 SELEX
Jolma et al.(2013)
TBX1_2 		0.858 0.885
TBX1
M03572_2.00 		Homo sapiens
AGGTGTGA
TCACACCT		 SELEX
Jolma et al.(2013)
TBX1_3 		0.858 0.885
TBX1
M03573_2.00 		Homo sapiens
YYTCACACMTYWRAGGTGTGAAA
TTTCACACCTYWRAKGTGTGARR		 SELEX
Jolma et al.(2013)
TBX1_4 		0.858 0.885
TBX1
M03574_2.00 		Homo sapiens
YTCACACCTDKAGGTGTGAA
TTCACACCTMHAGGTGTGAR		 SELEX
Jolma et al.(2013)
TBX1_5 		0.858 0.885
TBX1
M05821_2.00 		Homo sapiens
BDRGGTGTGARV
BYTCACACCYHV		 SELEX
Yin et al.(2017)
TBX1_eDBD_HT-SELEX 		0.858 0.885
Tbx1
M11386_2.00 		Mus musculus Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$TBX1_07 		0.858 0.885
TBX1
M05822_2.00 		Homo sapiens
DNWGGTGTGARN
NYTCACACCWNH		 SELEX
Yin et al.(2017)
TBX1_eDBD_Methyl-HT-SELEX 		0.858 0.885
For this family, TFs with SR scores > 0.734 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSMUSP00000037401 T-box 67 252

Links

Other T-box family TFs
Other Mus musculus TFs

Invalid Input OrderBy

113 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action