Tbx6 (Rattus norvegicus)
T-box

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00907 (T-box) IPR001699 ENSRNOG00000019771 T340435_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and RNA polymerase II-specific DNA-binding transcription factor binding activity. Predicted to be involved in several processes, including cell fate specification; heart development; and regulation of transcription, DNA-templated. Predicted to act upstream of or within several processes, including negative regulation of neuron maturation; regulation of gene expression; and somite rostral/caudal axis specification. Predicted to be located in chromatin and nucleus. Human ortholog(s) of this gene implicated in spondylocostal dysostosis. Orthologous to human TBX6 (T-box transcription factor 6). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
TBX6
M05805_2.00
Homo sapiens
NRSGTGTBAN

NTVACACSYN
SELEX
Yin et al.(2017)
TBX6_eDBD_HT-SELEX
0.884 0.956
TBX6
M05806_2.00
Homo sapiens
NTVRCACBHN

NDVGTGYBAN
SELEX
Yin et al.(2017)
TBX6_eDBD_Methyl-HT-SELEX
0.884 0.956
For this family, TFs with SR scores > 0.734 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSRNOP00000060687 T-box 93 273

Links

Other T-box family TFs
Other Rattus norvegicus TFs

Invalid Input OrderBy

34 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action