tbx-38 (Caenorhabditis elegans)
T-box

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00907 (T-box) IPR001699 WBGene00006557 T340946_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in pharynx development. Located in nucleus. Is expressed in several structures, including ABalaa; ABalap; ABalpa; ABalpp; and ABaraa. Human ortholog(s) of this gene implicated in asthma, nasal polyps, and aspirin intolerance and autistic disorder. Orthologous to human TBR1 (T-box brain transcription factor 1); TBX21 (T-box transcription factor 21); and EOMES (eomesodermin). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
tbx-38
M00714_2.00		 Caenorhabditis elegans
NDRGTGHKAN
NTMDCACYHN		 PBM
Narasimhan et al.(2015)
pTH9462		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
For this family, TFs with SR scores > 0.734 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M00714_2.00 T-box 12 195

DNA Binding Domains

Protein ID Domain From To Sequence
C24H11.3 T-box 12 195

Links

Other T-box family TFs
Other Caenorhabditis elegans TFs

1 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
tbx-37 Caenorhabditis elegans WBGene00006556 I 0.797