tbx-39 (Caenorhabditis elegans)
T-box

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00907 (T-box) IPR001699 WBGene00006558 T340947_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in cell fate specification and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is expressed in head muscle; head neurons; intestine; tail neurons; and ventral nerve cord. Human ortholog(s) of this gene implicated in asthma, nasal polyps, and aspirin intolerance and autistic disorder. Orthologous to human TBR1 (T-box brain transcription factor 1); TBX21 (T-box transcription factor 21); and EOMES (eomesodermin). [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
tbx-39
M00715_2.00		 Caenorhabditis elegans
NAACTTRGYNNN
NNNRCYAAGTTN		 PBM
Narasimhan et al.(2015)
pTH9884		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
tbx-40
M02497_2.00 		Caenorhabditis elegans
NNCTTGGYASN
NSTRCCAAGNN		 PBM
Weirauch et al.(2014)
pTH8411 		0.794 0.931
For this family, TFs with SR scores > 0.734 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M00715_2.00 T-box 9 187

DNA Binding Domains

Protein ID Domain From To Sequence
Y73F8A.16 T-box 9 187

Links

Other T-box family TFs
Other Caenorhabditis elegans TFs

1 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
tbx-40 Caenorhabditis elegans WBGene00006559 D 0.794