ENSP00000356795 (Macaca fascicularis)
T-box

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source
PF00907 (T-box) IPR001699 ENSP00000356795 T341064_2.00 GigaDB (2015-Oct-22)
NCBI Gene Info:
This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Mutations in this gene were found in patients with isolated deficiency of pituitary POMC-derived ACTH, suggesting an essential role for this gene in differentiation of the pituitary POMC lineage. ACTH deficiency is characterized by adrenal insufficiency symptoms such as weight loss, lack of appetite (anorexia), weakness, nausea, vomiting, and low blood pressure. [provided by RefSeq, Jul 2008]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
TBX19
M03562_2.00
Homo sapiens
NDTVRCACVTANGTGYKANN

NNTMRCACNTABGTGYBAHN
SELEX
Jolma et al.(2013)
TBX19_1
0.920 1.000
TBX19
M05803_2.00
Homo sapiens
NAGGTGYBAHWDTMRCACNTN

NANGTGYKAHWDTVRCACCTN
SELEX
Yin et al.(2017)
TBX19_eDBD_HT-SELEX
0.920 1.000
TBX19
M05804_2.00
Homo sapiens
NANGTGYKAHWDTVRCACSTN

NASGTGYBAHWDTMRCACNTN
SELEX
Yin et al.(2017)
TBX19_eDBD_Methyl-HT-SELEX
0.920 1.000
T
M05809_2.00
Homo sapiens
NANGTGYGAHWWNTVRCACCTN

NAGGTGYBANWWDTCRCACNTN
SELEX
Yin et al.(2017)
T_eDBD_HT-SELEX_1
0.876 0.835
T
M05810_2.00
Homo sapiens
DTCRCAYVTABGTGYGAH

DTCRCACVTABRTGYGAH
SELEX
Yin et al.(2017)
T_eDBD_HT-SELEX_2
0.876 0.835
T
M09427_2.00
Homo sapiens
BYNVCANNNVDGTGWKARDN

NHYTMWCACHBNNNTGBNRV
Misc
Kulakovskiy et al.(2013)
BRAC_HUMAN.H11MO.0.A
0.876 0.835
T
M09431_2.00
Mus musculus
VVNRAWTTSACASNYHDVTGBNMAN

NTKNVCABHDRNSTGTSAAWTYNBB
Misc
Kulakovskiy et al.(2013)
BRAC_MOUSE.H11MO.0.B
0.876 0.835
T
M09651_2.00
Mus musculus
NYTVDCASNNNNSTGHBARNN

NNYTVDCASNNNNSTGHBARN
Misc
Heinz et al.(2010)
Mesoendoderm-Brachyury_GSE54963
0.876 0.835
T
M11384_2.00
Homo sapiens
MKHBTSACACSTAGGTGTGAAATK

MATTTCACACCTASGTGTSAVDMK
Transfac
Matys et al.(2006)
V$BRACH_01
0.876 0.835
T
M05811_2.00
Homo sapiens
NABGTGYGAHWWNTVRCACSTN

NASGTGYBANWWDTCRCACVTN
SELEX
Yin et al.(2017)
T_eDBD_Methyl-HT-SELEX_1
0.876 0.835
T
M05812_2.00
Homo sapiens
DTMRCAYVTABGTGYKAH

DTMRCACVTABRTGYKAH
SELEX
Yin et al.(2017)
T_eDBD_Methyl-HT-SELEX_2
0.876 0.835
byn
M03984_2.00
Drosophila melanogaster
ABGTGYGADDD

HHHTCRCACVT
SELEX
Nitta et al.(2015)
byn_1
0.816 0.761
byn
M03985_2.00
Drosophila melanogaster
DNGTGYBAHWWDTVRCACNH

DNGTGYBAHWWDTVRCACNH
SELEX
Nitta et al.(2015)
byn_2
0.816 0.761
byn
M03986_2.00
Drosophila melanogaster
RDGTGYGADNDNDNNNNNNDRDGTGYGADD

HHTCRCACHYHNNNNNNHNHNHTCRCACHY
SELEX
Nitta et al.(2015)
byn_3
0.816 0.761
byn
M03987_2.00
Drosophila melanogaster
NNTMRCAYNWWNRTGYKAHN

NDTMRCAYNWWNRTGYKANN
SELEX
Nitta et al.(2015)
byn_4
0.816 0.761
byn
M06453_2.00
Drosophila melanogaster
ADGTGCDA

THGCACHT
B1H
Zhu et al.(2011)
byn_FlyReg_FBgn0011723
0.816 0.761
For this family, TFs with SR scores > 0.734 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000356795 T-box 43 218

Links

Other T-box family TFs
Other Macaca fascicularis TFs

177 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
AMTR_s00059p00116150 Amborella trichopoda AMTR_s00059p00116150 N 0.000
AT1G31040 Arabidopsis thaliana AT1G31040 N 0.000
BGIOSGA007635 Oryza indica BGIOSGA007635 N 0.000
BGIOSGA023427 Oryza indica BGIOSGA023427 N 0.000
Bo2g121040 Brassica oleracea Bo2g121040 N 0.000
Bo7g041160 Brassica oleracea Bo7g041160 N 0.000
Bostr.15697s0409 Boechera stricta Bostr.15697s0409 N 0.000
Bra014899 Brassica rapa Bra014899 N 0.000
Bra038403 Brassica rapa Bra038403 N 0.000
BRADI1G32050 Brachypodium distachyon BRADI1G32050 N 0.000
BRADI3G05380 Brachypodium distachyon BRADI3G05380 N 0.000
Cagra.1508s0089 Capsella grandiflora Cagra.1508s0089 N 0.000
Carubv10011663m.g Capsella rubella Carubv10011663m.g N 0.000
cassava11490.m1 Manihot esculenta cassava11490.m1 N 0.000
cassava17724.valid.m1 Manihot esculenta cassava17724.valid.m1 N 0.000
Cla010042 Citrullus lanatus Cla010042 N 0.000
Cla019628 Citrullus lanatus Cla019628 N 0.000
Cucsa.048750 Cucumis sativus Cucsa.048750 N 0.000
Cucsa.134530 Cucumis sativus Cucsa.134530 N 0.000
Eucgr.E00457 Eucalyptus grandis Eucgr.E00457 N 0.000
Eucgr.E04309 Eucalyptus grandis Eucgr.E04309 N 0.000
F775_02274 Aegilops tauschii F775_02274 N 0.000
fgenesh1_pm.C_scaffold_1002523 Arabidopsis lyrata fgenesh1_pm.C_scaffold_1002523 N 0.000
GLYMA05G26271 Glycine max GLYMA05G26271 N 0.000
GLYMA08G09191 Glycine max GLYMA08G09191 N 0.000
GLYMA15G17040 Glycine max GLYMA15G17040 N 0.000
GRMZM2G017882 Zea mays GRMZM2G017882 N 0.000
GSMUA_Achr9G30790_001 Musa acuminata GSMUA_Achr9G30790_001 N 0.000
GSMUA_AchrUn_randomG23740_001 Musa acuminata GSMUA_AchrUn_randomG23740_001 N 0.000
LjSGA_033751.1 Lotus japonicus LjSGA_033751.1 N 0.000
LPERR02G04770 Leersia perrieri LPERR02G04770 N 0.000
LPERR06G19930 Leersia perrieri LPERR06G19930 N 0.000
MLOC_21744 Hordeum vulgare MLOC_21744 N 0.000
OBART02G05520 Oryza barthii OBART02G05520 N 0.000
OBART06G24000 Oryza barthii OBART06G24000 N 0.000
OGLUM02G05380 Oryza glumaepatula OGLUM02G05380 N 0.000
OGLUM06G25260 Oryza glumaepatula OGLUM06G25260 N 0.000
OLONG_011712 Oryza longistaminata OLONG_011712 N 0.000
OLONG_022199 Oryza longistaminata OLONG_022199 N 0.000
OMERI06G23930 Oryza meridionalis OMERI06G23930 N 0.000
ONIVA02G05860 Oryza nivara ONIVA02G05860 N 0.000
ONIVA03G43780 Oryza nivara ONIVA03G43780 N 0.000
OPUNC06G21750 Oryza punctata OPUNC06G21750 N 0.000
ORGLA06G0201700 Oryza glaberrima ORGLA06G0201700 N 0.000
ORUFI02G05620 Oryza rufipogon ORUFI02G05620 N 0.000
OS02G0172800 Oryza sativa OS02G0172800 N 0.000
OS06G0666100 Oryza sativa OS06G0666100 N 0.000
Pavir.Aa03378 Panicum virgatum Pavir.Aa03378 N 0.000
Pavir.Ab00578 Panicum virgatum Pavir.Ab00578 N 0.000
Pavir.Da00255 Panicum virgatum Pavir.Da00255 N 0.000
PDK_20s1530701g001 Phoenix dactylifera PDK_20s1530701g001 N 0.000
PK04104.1 Cannabis sativa PK04104.1 N 0.000
Pm010795 Prunus mume Pm010795 N 0.000
POPTR_0001s15920 Populus trichocarpa POPTR_0001s15920 N 0.000
PRUPE_ppa024886mg Prunus persica PRUPE_ppa024886mg N 0.000
SapurV1A.0104s0310 Salix purpurea SapurV1A.0104s0310 N 0.000
SapurV1A.0210s0200 Salix purpurea SapurV1A.0210s0200 N 0.000
Sb04g004830 Sorghum bicolor Sb04g004830 N 0.000
Sb10g026620 Sorghum bicolor Sb10g026620 N 0.000
Si018139m.g Setaria italica Si018139m.g N 0.000
Solyc02g068510.1 Solanum lycopersicum Solyc02g068510.1 N 0.000
TCM_006017 Theobroma cacao TCM_006017 N 0.000
Thhalv10009789m.g Eutrema salsugineum Thhalv10009789m.g N 0.000
Traes_6BS_4DA724E79 Triticum aestivum Traes_6BS_4DA724E79 N 0.000
Traes_6DS_CA4C01DEF Triticum aestivum Traes_6DS_CA4C01DEF N 0.000
Traes_7AL_5E9E6A334 Triticum aestivum Traes_7AL_5E9E6A334 N 0.000
Traes_7DL_B446D4CC6 Triticum aestivum Traes_7DL_B446D4CC6 N 0.000
TRIUR3_33737 Triticum urartu TRIUR3_33737 N 0.000