ENSP00000358677 (Macaca fascicularis)
T-box

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source
PF00907 (T-box) IPR001699 ENSP00000358677 T341068_2.00 GigaDB (2015-Oct-22)
NCBI Gene Info:
This genes codes for a member of an evolutionarily conserved family of transcription factors that plays a crucial role in embryonic development. The family is characterized by the presence of the DNA-binding T-box domain and is divided into five sub-families based on sequence conservation in this domain. The encoded protein belongs to the vertebrate specific Tbx1 sub-family. The protein acts as a transcriptional repressor by antagonizing transcriptional activators in the T-box family. The protein forms homo- or heterodimers with other transcription factors of the T-box family or other transcription factors. [provided by RefSeq, Nov 2012]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score
DBD
Identity
TBX18
M05797_2.00
Homo sapiens
DDAGGTGTGARV

BYTCACACCTHH
SELEX
Yin et al.(2017)
TBX18_eDBD_HT-SELEX
0.920 1.000
TBX18
M11380_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$TBX18_01
0.920 1.000
TBX18
M05798_2.00
Homo sapiens
NDAGGYGTGAAN

NTTCACRCCTHN
SELEX
Yin et al.(2017)
TBX18_eDBD_Methyl-HT-SELEX
0.920 1.000
TBX15
M03554_2.00
Homo sapiens
AGGTGTGAAATTCACACCT

AGGTGTGAATTTCACACCT
SELEX
Jolma et al.(2013)
TBX15_1
0.901 0.929
TBX15
M03555_2.00
Homo sapiens
AGGTGTGA

TCACACCT
SELEX
Jolma et al.(2013)
TBX15_2
0.901 0.929
TBX15
M05795_2.00
Homo sapiens
NRSGTGTBAN

NTVACACSYN
SELEX
Yin et al.(2017)
TBX15_eDBD_HT-SELEX
0.901 0.929
TBX15
M11378_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$TBX15_01
0.901 0.929
TBX15
M11379_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$TBX15_02
0.901 0.929
TBX15
M05796_2.00
Homo sapiens
NDSGYGTBAN

NTVACRCSHN
SELEX
Yin et al.(2017)
TBX15_eDBD_Methyl-HT-SELEX
0.901 0.929
TBX22
M11383_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$TBX22_01
0.830 0.742
mid
M03994_2.00
Drosophila melanogaster
DAGGTGTKAN

NTMACACCTH
SELEX
Nitta et al.(2015)
mid_1
0.776 0.604
Tbx20
M00835_2.00
Mus musculus
NRRGTGTBAN

NTVACACYYN
PBM
Weirauch et al.(2013)
pTH3777
0.752 0.659
TBX20
M03565_2.00
Homo sapiens
AGGTGTKARVGYGTGA

TCACRCBYTMACACCT
SELEX
Jolma et al.(2013)
TBX20_1
0.752 0.659
TBX20
M03566_2.00
Homo sapiens
AGGTGTGAAWDTSACACBT

AVGTGTSAHWTTCACACCT
SELEX
Jolma et al.(2013)
TBX20_2
0.752 0.659
TBX20
M03567_2.00
Homo sapiens
NNNDAGGTGTGAAND

HNTTCACACCTHNNN
SELEX
Jolma et al.(2013)
TBX20_3
0.752 0.659
TBX20
M03568_2.00
Homo sapiens
DAGGTGTGAWR

YWTCACACCTH
SELEX
Jolma et al.(2013)
TBX20_4
0.752 0.659
TBX20
M03569_2.00
Homo sapiens
AGGTGTKANGKTGTSA

TSACAMCNTMACACCT
SELEX
Jolma et al.(2013)
TBX20_5
0.752 0.659
TBX20
M05813_2.00
Homo sapiens
DAGGTGTKARSGTGTGAA

TTCACACSYTMACACCTH
SELEX
Yin et al.(2017)
TBX20_eDBD_HT-SELEX_1
0.752 0.659
TBX20
M05814_2.00
Homo sapiens
NAGGTGTGAAWTTCACACCTN

NAGGTGTGAAWTTCACACCTN
SELEX
Yin et al.(2017)
TBX20_eDBD_HT-SELEX_2
0.752 0.659
TBX20
M05817_2.00
Homo sapiens
DRRGTGTBADVGYGTBAN

NTVACRCBHTVACACYYH
SELEX
Yin et al.(2017)
TBX20_FL_HT-SELEX_1
0.752 0.659
TBX20
M05818_2.00
Homo sapiens
WTCACACYTAGGTGTKAM

KTMACACCTARGTGTGAW
SELEX
Yin et al.(2017)
TBX20_FL_HT-SELEX_2
0.752 0.659
Tbx20
M09430_2.00
Mus musculus
NDSTGNTGACAGSN

NSCTGTCANCASHN
Misc
Kulakovskiy et al.(2013)
TBX20_MOUSE.H11MO.0.C
0.752 0.659
Tbx20
M09650_2.00
Mus musculus
SCTGTCADCASN

NSTGHTGACAGS
Misc
Heinz et al.(2010)
Heart-Tbx20_GSE29636
0.752 0.659
TBX20
M11385_2.00
Homo sapiens Transfac license required
Transfac license required
Transfac
Matys et al.(2006)
V$TBX20_05
0.752 0.659
TBX20
M05815_2.00
Homo sapiens
DAGGTGTKAASGYGTKAA

TTMACRCSTTMACACCTH
SELEX
Yin et al.(2017)
TBX20_eDBD_Methyl-HT-SELEX_1
0.752 0.659
TBX20
M05816_2.00
Homo sapiens
DASGTGTGAWWWTCACACCTH

DAGGTGTGAWWWTCACACSTH
SELEX
Yin et al.(2017)
TBX20_eDBD_Methyl-HT-SELEX_2
0.752 0.659
TBX20
M05819_2.00
Homo sapiens
DRGGYGTBARVGYGTKAN

NTMACRCBYTVACRCCYH
SELEX
Yin et al.(2017)
TBX20_FL_Methyl-HT-SELEX_1
0.752 0.659
TBX20
M05820_2.00
Homo sapiens
TTMACRCCTAVGTGTGAA

TTCACACBTAGGYGTKAA
SELEX
Yin et al.(2017)
TBX20_FL_Methyl-HT-SELEX_2
0.752 0.659
For this family, TFs with SR scores > 0.734 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000358677 T-box 141 330

Links

Other T-box family TFs
Other Macaca fascicularis TFs

263 Related TFs

Name Species Gene ID Motif Evidence SR
Score
Action
Aan_R003640 Calypte anna Aan_R003640 I 0.000
Aan_R014715 Calypte anna Aan_R014715 I 0.000
Afo_R006826 Aptenodytes forsteri Afo_R006826 I 0.000
Afo_R007816 Aptenodytes forsteri Afo_R007816 I 0.000
Brh_R008256 Buceros rhinoceros Brh_R008256 I 0.000
Brh_R010932 Buceros rhinoceros Brh_R010932 I 0.000
Cmyd_10007839 Chelonia mydas Cmyd_10007839 I 0.000
Cmyd_10009086 Chelonia mydas Cmyd_10009086 I 0.000
ENSAMEG00000004878 Ailuropoda melanoleuca ENSAMEG00000004878 I 0.000
ENSAMEG00000008405 Ailuropoda melanoleuca ENSAMEG00000008405 I 0.000
ENSAMEG00000008708 Ailuropoda melanoleuca ENSAMEG00000008708 I 0.000
ENSAMXG00000002477 Astyanax mexicanus ENSAMXG00000002477 I 0.000
ENSAMXG00000003125 Astyanax mexicanus ENSAMXG00000003125 I 0.000
ENSAMXG00000006646 Astyanax mexicanus ENSAMXG00000006646 I 0.000
ENSAMXG00000017236 Astyanax mexicanus ENSAMXG00000017236 I 0.000
ENSAPLG00000004361 Anas platyrhynchos ENSAPLG00000004361 I 0.000
ENSAPLG00000005128 Anas platyrhynchos ENSAPLG00000005128 I 0.000
ENSBTAP00000008704-D1 Bos grunniens ENSBTAP00000008704-D1 I 0.000
ENSCING00000012018 Ciona intestinalis ENSCING00000012018 I 0.000
ENSCJAG00000003076 Callithrix jacchus ENSCJAG00000003076 I 0.000
ENSCJAG00000013342 Callithrix jacchus ENSCJAG00000013342 I 0.000
ENSCSAG00000004897 Chlorocebus sabaeus ENSCSAG00000004897 I 0.000
ENSCSAG00000015361 Chlorocebus sabaeus ENSCSAG00000015361 I 0.000
ENSCSAG00000016668 Chlorocebus sabaeus ENSCSAG00000016668 I 0.000
ENSCSAVG00000009575 Ciona savignyi ENSCSAVG00000009575 I 0.000
ENSECAG00000008016 Equus caballus ENSECAG00000008016 I 0.000
ENSFALG00000005113 Ficedula albicollis ENSFALG00000005113 I 0.000
ENSFALG00000013217 Ficedula albicollis ENSFALG00000013217 I 0.000
ENSGACG00000004834 Gasterosteus aculeatus ENSGACG00000004834 I 0.000
ENSGALG00000012329 Gallus gallus ENSGALG00000012329 I 0.000
ENSGALG00000014639 Gallus gallus ENSGALG00000014639 I 0.000
ENSGMOG00000007975 Gadus morhua ENSGMOG00000007975 I 0.000
ENSGMOG00000010335 Gadus morhua ENSGMOG00000010335 I 0.000
ENSLACG00000017364 Latimeria chalumnae ENSLACG00000017364 I 0.000
ENSLOCG00000002028 Lepisosteus oculatus ENSLOCG00000002028 I 0.000
ENSLOCG00000005938 Lepisosteus oculatus ENSLOCG00000005938 I 0.000
ENSLOCG00000011983 Lepisosteus oculatus ENSLOCG00000011983 I 0.000
ENSMEUG00000009702 Macropus eugenii ENSMEUG00000009702 I 0.000
ENSMEUG00000013134 Macropus eugenii ENSMEUG00000013134 I 0.000
ENSMGAG00000003540 Meleagris gallopavo ENSMGAG00000003540 I 0.000
ENSMMUP00000002494 Macaca fascicularis ENSMMUP00000002494 I 0.000
ENSMPUG00000000986 Mustela putorius furo ENSMPUG00000000986 I 0.000
ENSMPUG00000001825 Mustela putorius furo ENSMPUG00000001825 I 0.000
ENSMPUG00000018143 Mustela putorius furo ENSMPUG00000018143 I 0.000
ENSNLEG00000000944 Nomascus leucogenys ENSNLEG00000000944 I 0.000
ENSNLEG00000003160 Nomascus leucogenys ENSNLEG00000003160 I 0.000
ENSNLEG00000017337 Nomascus leucogenys ENSNLEG00000017337 I 0.000
ENSOARG00000006674 Ovis aries ENSOARG00000006674 I 0.000
ENSOARG00000013052 Ovis aries ENSOARG00000013052 I 0.000
ENSOARG00000017420 Ovis aries ENSOARG00000017420 I 0.000
ENSONIG00000003608 Oreochromis niloticus ENSONIG00000003608 I 0.000
ENSONIG00000004472 Oreochromis niloticus ENSONIG00000004472 I 0.000
ENSONIG00000005084 Oreochromis niloticus ENSONIG00000005084 I 0.000
ENSONIG00000006298 Oreochromis niloticus ENSONIG00000006298 I 0.000
ENSP00000228682 Macaca fascicularis ENSP00000228682 I 0.000
ENSP00000379258 Macaca fascicularis ENSP00000379258 I 0.000
ENSP00000390436-D1 Bos grunniens ENSP00000390436-D1 I 0.000
ENSPANG00000014545 Papio anubis ENSPANG00000014545 I 0.000
ENSPANG00000017044 Papio anubis ENSPANG00000017044 I 0.000
ENSPANG00000024168 Papio anubis ENSPANG00000024168 I 0.000
ENSPFOG00000005116 Poecilia formosa ENSPFOG00000005116 I 0.000
ENSPFOG00000006269 Poecilia formosa ENSPFOG00000006269 I 0.000
ENSPFOG00000014778 Poecilia formosa ENSPFOG00000014778 I 0.000
ENSPFOG00000019294 Poecilia formosa ENSPFOG00000019294 I 0.000
ENSPPYG00000004689 Pongo abelii ENSPPYG00000004689 I 0.000
ENSPPYG00000012778 Pongo abelii ENSPPYG00000012778 I 0.000
ENSPPYG00000017613 Pongo abelii ENSPPYG00000017613 I 0.000
ENSPSIG00000008752 Pelodiscus sinensis ENSPSIG00000008752 I 0.000
ENSPSIG00000017804 Pelodiscus sinensis ENSPSIG00000017804 I 0.000
ENSSHAG00000004233 Sarcophilus harrisii ENSSHAG00000004233 I 0.000
ENSSHAG00000006652 Sarcophilus harrisii ENSSHAG00000006652 I 0.000
ENSSHAG00000009727 Sarcophilus harrisii ENSSHAG00000009727 I 0.000
ENSSTOG00000004582 Ictidomys tridecemlineatus ENSSTOG00000004582 I 0.000
ENSSTOG00000020366 Ictidomys tridecemlineatus ENSSTOG00000020366 I 0.000
ENSSTOG00000020844 Ictidomys tridecemlineatus ENSSTOG00000020844 I 0.000
ENSTGUG00000001834 Taeniopygia guttata ENSTGUG00000001834 I 0.000
ENSTSYG00000009406 Tarsius syrichta ENSTSYG00000009406 I 0.000
ENSXMAG00000001777 Xiphophorus maculatus ENSXMAG00000001777 I 0.000
ENSXMAG00000006443 Xiphophorus maculatus ENSXMAG00000006443 I 0.000
ENSXMAG00000017965 Xiphophorus maculatus ENSXMAG00000017965 I 0.000
fgenesh2_pg.scaffold_137000068 Branchiostoma floridae fgenesh2_pg.scaffold_137000068 I 0.000
fgenesh2_pg.scaffold_169000072 Branchiostoma floridae fgenesh2_pg.scaffold_169000072 I 0.000
Gfo_R001212 Geospiza fortis Gfo_R001212 I 0.000
Gfo_R007869 Geospiza fortis Gfo_R007869 I 0.000
Gfo_R013682 Geospiza fortis Gfo_R013682 I 0.000
GLI1 Pteropus vampyrus ENSPVAG00000012109 I 0.000
GLI1 Felis catus ENSFCAG00000002081 I 0.000
GLI1 Bos taurus ENSBTAG00000006631 I 0.000
GLI1 Anolis carolinensis ENSACAG00000006541 I 0.000
GLI1 Otolemur garnettii ENSOGAG00000005219 I 0.000
GLI1 Callithrix jacchus ENSCJAG00000007324 I 0.000
gli1 Xenopus tropicalis XB-GENE-482644 I 0.000
GLI1 Procavia capensis ENSPCAG00000015756 I 0.000
GLI1 Ochotona princeps ENSOPRG00000006483 I 0.000
gli1 Oryzias latipes ENSORLG00000005455 I 0.000
GLI1 Pan troglodytes ENSPTRG00000005133 I 0.000
GLI1 Oryctolagus cuniculus ENSOCUG00000011128 I 0.000
Gli1 Rattus norvegicus ENSRNOG00000025120 I 0.000
GLI1 Tursiops truncatus ENSTTRG00000013086 I 0.000
gli1 Gasterosteus aculeatus ENSGACG00000006458 I 0.000
GLI1 Loxodonta africana ENSLAFG00000022910 I 0.000
GLI1 Homo sapiens ENSG00000111087 D 0.000
gli1 Tetraodon nigroviridis ENSTNIG00000007058 I 0.000
GLI1 Myotis lucifugus ENSMLUG00000001013 I 0.000
GLI1 Macaca mulatta ENSMMUG00000022058 I 0.000
GLI1 Echinops telfairi ENSETEG00000006674 I 0.000
GLI1 Gorilla gorilla ENSGGOG00000001974 I 0.000
GLI1 Cavia porcellus ENSCPOG00000005414 I 0.000
gli1 Takifugu rubripes ENSTRUG00000014998 I 0.000
GLI1 Canis familiaris ENSCAFG00000000223 I 0.000
gli1 Danio rerio ENSDARG00000101244 I 0.000
GLI1 Dasypus novemcinctus ENSDNOG00000017512 I 0.000
Gli1 Dipodomys ordii ENSDORG00000007124 I 0.000
GLI1 Equus caballus ENSECAG00000011246 I 0.000
Gli1 Mus musculus ENSMUSG00000025407 D 0.000
gli1.S Xenopus laevis XB-GENE-864895 I 0.000
GLI2 Tursiops truncatus ENSTTRG00000002058 I 0.000
GLI2 Taeniopygia guttata ENSTGUG00000004599 I 0.000
GLI2 Sus scrofa ENSSSCG00000015733 I 0.000
Gli2 Rattus norvegicus ENSRNOG00000007261 I 0.000
GLI2 Pan troglodytes ENSPTRG00000012413 I 0.000
GLI2 Bos taurus ENSBTAG00000011682 I 0.000
GLI2 Macaca mulatta ENSMMUG00000001868 I 0.000
GLI2 Dasypus novemcinctus ENSDNOG00000008730 I 0.000
GLI2 Gorilla gorilla ENSGGOG00000009653 I 0.000
GLI2 Gallus gallus ENSGALG00000011630 I 0.000
GLI2 Homo sapiens ENSG00000074047 D 0.000
GLI2 Felis catus ENSFCAG00000014531 I 0.000
GLI2 Anolis carolinensis ENSACAG00000004133 I 0.000
GLI2 Cavia porcellus ENSCPOG00000015189 I 0.000
GLI2 Canis familiaris ENSCAFG00000004821 I 0.000
Gli2 Mus musculus ENSMUSG00000048402 D 0.000
GLI2 Oryctolagus cuniculus ENSOCUG00000000638 I 0.000
GLI2 Monodelphis domestica ENSMODG00000000245 I 0.000
GLI2 Procavia capensis ENSPCAG00000001704 I 0.000
GLI2 Meleagris gallopavo ENSMGAG00000011872 I 0.000
GLI2 Otolemur garnettii ENSOGAG00000032438 I 0.000
gli2.L Xenopus laevis XB-GENE-17342592 I 0.000
gli2.S Xenopus laevis XB-GENE-6251939 I 0.000
gli2a Danio rerio ENSDARG00000025641 I 0.000
gli2b Takifugu rubripes ENSTRUG00000007692 I 0.000
gli2b Danio rerio ENSDARG00000020884 I 0.000
gli2b Tetraodon nigroviridis ENSTNIG00000013668 I 0.000
gli2b Gasterosteus aculeatus ENSGACG00000001547 I 0.000
gli2b Takifugu rubripes ENSTRUG00000010444 I 0.000
gli2b Oryzias latipes ENSORLG00000012490 I 0.000
gli2b Takifugu rubripes ENSTRUG00000001954 I 0.000
gli2b Tetraodon nigroviridis ENSTNIG00000017828 I 0.000
gli2b Tetraodon nigroviridis ENSTNIG00000010251 I 0.000
GLI3 Echinops telfairi ENSETEG00000003955 I 0.000
GLI3 Equus caballus ENSECAG00000009281 I 0.000
GLI3 Dasypus novemcinctus ENSDNOG00000049286 I 0.000
GLI3 Anolis carolinensis ENSACAG00000017547 I 0.000
GLI3 Bos taurus ENSBTAG00000010671 I 0.000
GLI3 Canis familiaris ENSCAFG00000003535 I 0.000
GLI3 Procavia capensis ENSPCAG00000015092 I 0.000
gli3 Danio rerio ENSDARG00000052131 I 0.000
GLI3 Choloepus hoffmanni ENSCHOG00000003774 I 0.000
GLI3 Callithrix jacchus ENSCJAG00000007690 I 0.000
GLI3 Cavia porcellus ENSCPOG00000013233 I 0.000
GLI3 Homo sapiens ENSG00000106571 D 0.000
GLI3 Felis catus ENSFCAG00000011989 I 0.000
GLI3 Myotis lucifugus ENSMLUG00000015711 I 0.000
Gli3 Rattus norvegicus ENSRNOG00000014395 I 0.000
GLI3 Tupaia belangeri ENSTBEG00000006673 I 0.000
GLI3 Macaca mulatta ENSMMUG00000013614 I 0.000
GLI3 Otolemur garnettii ENSOGAG00000012651 I 0.000
GLI3 Monodelphis domestica ENSMODG00000002714 I 0.000
Gli3 Mus musculus ENSMUSG00000021318 D 0.000
GLI3 Oryctolagus cuniculus ENSOCUG00000006563 I 0.000
GLI3 Microcebus murinus ENSMICG00000010785 I 0.000
GLI3 Meleagris gallopavo ENSMGAG00000012277 I 0.000
GLI3 Pan troglodytes ENSPTRG00000019117 I 0.000
GLI3 Tursiops truncatus ENSTTRG00000003628 I 0.000
GLI3 Ochotona princeps ENSOPRG00000011225 I 0.000
GLI3 Gorilla gorilla ENSGGOG00000002026 I 0.000
GLI3 Ornithorhynchus anatinus ENSOANG00000010699 I 0.000
GLI3 Pteropus vampyrus ENSPVAG00000015920 I 0.000
GLI3 Loxodonta africana ENSLAFG00000008944 I 0.000
gli3.L Xenopus laevis XB-GENE-865509 I 0.000
HelroG111329 Helobdella robusta HelroG111329 I 0.000
Myotis_brandtii_GLI1_10018379 Myotis brandtii Myotis_brandtii_GLI1_10018379 I 0.000
Myotis_brandtii_Gli2_10019076 Myotis brandtii Myotis_brandtii_Gli2_10019076 I 0.000
Ogr02489 Ophisaurus gracilis Ogr02489 I 0.000
Pvit_05813 Pogona vitticeps Pvit_05813 I 0.000
Pvit_06470 Pogona vitticeps Pvit_06470 I 0.000
Pvit_19093 Pogona vitticeps Pvit_19093 I 0.000
Tal_R006208 Tyto alba Tal_R006208 I 0.000
Tal_R009020 Tyto alba Tal_R009020 I 0.000
XP_002933449 Xenopus tropicalis XP_002933449 I 0.000
XP_002933450 Xenopus tropicalis XP_002933450 I 0.000