|
|
ENSBTAP00000010109-D2
(Bos grunniens)
TBP
|
TF Information |
|---|
| Pfam ID |
Interpro ID |
Gene ID |
CIS-BP ID |
Sequence source |
| PF00352 (TBP) |
IPR000814 |
ENSBTAP00000010109-D2 |
T343067_2.00 |
GigaDB (2015-Oct-22) |
| NCBI Gene Info:This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016] |
Directly determined binding motifs |
|---|
| Name/Motif ID |
Species |
Forward |
Reverse |
Type/Study/Study ID |
SR
Score |
DBD
Identity |
| No direct experiments |
|
|
|
|
|
Motifs from related TFs |
|---|
| Name/Motif ID |
Species |
Forward |
Reverse |
Type/Study/Study ID |
SR
Score |
DBD
Identity |
Tbp
M00216_2.00 |
Mus musculus |
NWWWWAW |
WTWWWWN |
PBM
Badis et al.(2009)
Tbp_pr781
|
1.000
|
1.000
|
TBP
M08231_2.00 |
Homo sapiens |
YATTTGCATD |
HATGCAAATR |
ChIP-seq
Contrino et al.(2012)
Mv129
|
1.000
|
1.000
|
TBP
M09432_2.00 |
Homo sapiens |
MTATAWAWRS |
SYWTWTATAK |
Misc
Kulakovskiy et al.(2013)
TBP_HUMAN.H11MO.0.A
|
1.000
|
1.000
|
Tbp
M09433_2.00 |
Mus musculus |
VTATAAAARS |
SYTTTTATAB |
Misc
Kulakovskiy et al.(2013)
TBP_MOUSE.H11MO.0.A
|
1.000
|
1.000
|
TBP
M11388_2.00 |
Homo sapiens |
VTATAWAWRVVNNNN |
NNNNBBYWTWTATAB |
Transfac
Matys et al.(2006)
V$TATA_01
|
1.000
|
1.000
|
TBP
M11389_2.00 |
Homo sapiens |
NCYWTAAAAD |
HTTTTAWRGN |
Transfac
Matys et al.(2006)
V$TATA_C
|
1.000
|
1.000
|
TBP
M11390_2.00 |
Homo sapiens |
KATAAATW |
WATTTATM |
Transfac
Matys et al.(2006)
V$TBP_01
|
1.000
|
1.000
|
TBP
M11391_2.00 |
Homo sapiens |
Transfac license required
|
Transfac license required
|
Transfac
Matys et al.(2006)
V$TBP_Q6_01
|
1.000
|
1.000
|
TBP
M11392_2.00 |
Homo sapiens |
Transfac license required
|
Transfac license required
|
Transfac
Matys et al.(2006)
V$TBP_Q6
|
1.000
|
1.000
|
TBP
M11491_2.00 |
Homo sapiens |
VTATAWAWRVVNNNN |
NNNNBBYWTWTATAB |
Unknown
Mathelier et al.(2014)
MA0108.2
|
1.000
|
1.000
|
SPT15
M01567_2.00 |
Saccharomyces cerevisiae |
NNDWDAW |
WTHWHNN |
PBM
Zhu et al.(2009)
Spt15
|
0.808
|
0.808
|
SPT15
M08609_2.00 |
Saccharomyces cerevisiae |
NNBBHWTATATATWNCNNDNB |
VNHNNGNWATATATAWDVVNN |
Misc
DeBoer et al.(2011)
YER148W_798
|
0.808
|
0.808
|
SPT15
M11393_2.00 |
Saccharomyces cerevisiae |
Transfac license required
|
Transfac license required
|
Transfac
Matys et al.(2006)
F$TBP_Q6
|
0.808
|
0.808
|
| For this family, TFs with SR scores > 0.700 will likely have a similar motif |