Tead4 (Mus musculus)
TEA

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF01285 (TEA) IPR000818 ENSMUSG00000030353 T346585_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
This gene product is a member of the transcriptional enhancer factor (TEF) family of transcription factors, which contain the TEA/ATTS DNA-binding domain. It is preferentially expressed in the skeletal muscle, and binds to the M-CAT regulatory element found in promoters of muscle-specific genes to direct their gene expression. This factor may play a role in the embryonic development of skeletal muscle. Alternatively spliced transcripts encoding distinct isoforms, which are translated through the use of a non-AUG (AUU) initiation codon, have been described for this gene. [provided by RefSeq, Jul 2008]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Tead4
M09436_2.00		 Mus musculus
VNRHBHNWGGAATKY
RMATTCCWNDVDYNB		 Misc
Kulakovskiy et al.(2013)
TEAD4_MOUSE.H11MO.0.A		 (Direct) (Direct)
Tead4
M09652_2.00		 Mus musculus
NNNGGAATBY
RVATTCCNNN		 Misc
Heinz et al.(2010)
Tropoblast-Tead4_GSE37350		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
TEAD4
M03579_2.00 		Homo sapiens
NHRGAATKYN
NRMATTCYDN		 SELEX
Jolma et al.(2013)
TEAD4_1 		0.935 0.935
TEAD1
M03577_2.00 		Homo sapiens
DHGGAATGYN
NRCATTCCDH		 SELEX
Jolma et al.(2013)
TEAD1_1 		0.853 0.853
TEAD4
M09435_2.00 		Homo sapiens
NDBNNWGGAATKY
RMATTCCWNNVHN		 Misc
Kulakovskiy et al.(2013)
TEAD4_HUMAN.H11MO.0.A 		0.935 0.935
TEAD1
M03578_2.00 		Homo sapiens
HGGWATKYNHGGAATGY
RCATTCCDNRMATWCCD		 SELEX
Jolma et al.(2013)
TEAD1_2 		0.853 0.853
TEAD4
M11409_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$TEF3_Q3 		0.935 0.935
TEAD1
M05825_2.00 		Homo sapiens
HGGWATGYN
NRCATWCCD		 SELEX
Yin et al.(2017)
TEAD1_FL_HT-SELEX 		0.853 0.853
TEAD1
M09434_2.00 		Homo sapiens
DBBNWGGAATGY
RCATTCCWNVVH		 Misc
Kulakovskiy et al.(2013)
TEAD1_HUMAN.H11MO.0.A 		0.853 0.853
Tead1
M09438_2.00 		Mus musculus
BSYWGGAATGY
RCATTCCWRSV		 Misc
Kulakovskiy et al.(2013)
TEAD1_MOUSE.H11MO.0.A 		0.853 0.853
TEAD1
M11404_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$TEF_01 		0.922 0.922
TEAD1
M11405_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$TEF_07 		0.922 0.922
TEAD1
M11406_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$TEF1_Q6_03 		0.922 0.922
TEAD1
M11407_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$TEF1_Q6_04 		0.922 0.922
TEAD1
M11408_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$TEF1_Q6 		0.922 0.922
TEAD1
M05826_2.00 		Homo sapiens
HGGWATGYN
NRCATWCCD		 SELEX
Yin et al.(2017)
TEAD1_FL_Methyl-HT-SELEX 		0.922 0.922
TEAD3
M03575_2.00 		Homo sapiens
HGGWATGHNHRGAATGY
RCATTCYDNDCATWCCD		 SELEX
Jolma et al.(2013)
TEAD3_1 		0.883 0.883
TEAD3
M03576_2.00 		Homo sapiens
HGGAATGY
RCATTCCD		 SELEX
Jolma et al.(2013)
TEAD3_2 		0.883 0.883
TEAD3
M11401_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$TEF5_Q2 		0.883 0.883
TEAD3
M11402_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$TEF5_Q6_01 		0.883 0.883
sd
M03995_2.00 		Drosophila melanogaster
HGGAATGYRN
NYRCATTCCD		 SELEX
Nitta et al.(2015)
sd_1 		0.831 0.831
sd
M03996_2.00 		Drosophila melanogaster
DDWGGAATGYRN
NYRCATTCCWHH		 SELEX
Nitta et al.(2015)
sd_2 		0.831 0.831
sd
M06455_2.00 		Drosophila melanogaster
NYBHNRWATKWH
DWMATWYNDVRN		 B1H
Zhu et al.(2011)
sd_FlyReg_FBgn0003345 		0.831 0.831
sd
M07545_2.00 		Drosophila melanogaster
NYBHNRWATKWH
DWMATWYNDVRN		 DNaseI footprinting
Mathelier et al.(2014)
MA0243.1 		0.831 0.831
sd
M11410_2.00 		Drosophila melanogaster Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
I$SD_Q6 		0.831 0.831
TEAD2
M05823_2.00 		Homo sapiens
NWGGAATGYR
YRCATTCCWN		 SELEX
Yin et al.(2017)
TEAD2_FL_HT-SELEX 		0.818 0.818
TEAD2
M08175_2.00 		Homo sapiens
NNNWGGAATGTNN
NNACATTCCWNNN		 ChIP-seq
Mathelier et al.(2014)
MA1121.1 		0.818 0.818
Tead2
M09437_2.00 		Mus musculus
SCWGGAATGYNN
NNRCATTCCWGS		 Misc
Kulakovskiy et al.(2013)
TEAD2_MOUSE.H11MO.0.C 		0.818 0.818
Tead2
M09653_2.00 		Mus musculus
BCWGGAATGY
RCATTCCWGV		 Misc
Heinz et al.(2010)
Py2T-Tead2_GSE55709 		0.818 0.818
TEAD2
M11403_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$ETF_Q6_01 		0.818 0.818
TEAD2
M05824_2.00 		Homo sapiens
NHGGAATGYR
YRCATTCCDN		 SELEX
Yin et al.(2017)
TEAD2_FL_Methyl-HT-SELEX 		0.818 0.818
ENSTNIG00000008857_CONSTRUCT
M01323_2.00 		PBM CONSTRUCTS
NRGWATKYN
NRMATWCYN		 PBM
Lambert et al.(2019)
pTH9815 		0.753 0.753
For this family, TFs with SR scores > 0.700 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSMUSP00000006311 TEA 25 277
ENSMUSP00000107784 TEA 24 102
ENSMUSP00000118083 TEA 24 102
ENSMUSP00000120941 TEA 21 54

Links

Other TEA family TFs
Other Mus musculus TFs

Invalid Input OrderBy

316 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action