TF Information

HHAL001589-PA *(Halyomorpha halys)* TEA
Pfam ID	Interpro ID	Gene ID	CIS-BP ID	Sequence source
PF01285 (TEA)	IPR000818	HHAL001589-PA	T347022_2.00	Misc (2018-Jan-19)
NCBI Gene Info: This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016]
Directly determined binding motifs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
No direct experiments
Motifs from related TFs
Name/Motif ID	Species	Forward	Reverse	Type/Study/Study ID	SR Score	DBD Identity
sd M03995_2.00	Drosophila melanogaster	HGGAATGYRN	NYRCATTCCD	SELEX Nitta et al.(2015) sd_1	0.755	0.755
sd M03996_2.00	Drosophila melanogaster	DDWGGAATGYRN	NYRCATTCCWHH	SELEX Nitta et al.(2015) sd_2	0.755	0.755
sd M06455_2.00	Drosophila melanogaster	NYBHNRWATKWH	DWMATWYNDVRN	B1H Zhu et al.(2011) sd_FlyReg_FBgn0003345	0.755	0.755
sd M07545_2.00	Drosophila melanogaster	NYBHNRWATKWH	DWMATWYNDVRN	DNaseI footprinting Mathelier et al.(2014) MA0243.1	0.755	0.755
sd M11410_2.00	Drosophila melanogaster	Transfac license required	Transfac license required	Transfac Matys et al.(2006) I$SD_Q6	0.755	0.755
TEAD1 M03577_2.00	Homo sapiens	DHGGAATGYN	NRCATTCCDH	SELEX Jolma et al.(2013) TEAD1_1	0.717	0.717
TEAD1 M03578_2.00	Homo sapiens	HGGWATKYNHGGAATGY	RCATTCCDNRMATWCCD	SELEX Jolma et al.(2013) TEAD1_2	0.717	0.717
TEAD1 M05825_2.00	Homo sapiens	HGGWATGYN	NRCATWCCD	SELEX Yin et al.(2017) TEAD1_FL_HT-SELEX	0.717	0.717
TEAD2 M05823_2.00	Homo sapiens	NWGGAATGYR	YRCATTCCWN	SELEX Yin et al.(2017) TEAD2_FL_HT-SELEX	0.717	0.717
TEAD2 M08175_2.00	Homo sapiens	NNNWGGAATGTNN	NNACATTCCWNNN	ChIP-seq Mathelier et al.(2014) MA1121.1	0.717	0.717
TEAD1 M09434_2.00	Homo sapiens	DBBNWGGAATGY	RCATTCCWNVVH	Misc Kulakovskiy et al.(2013) TEAD1_HUMAN.H11MO.0.A	0.717	0.717
Tead1 M09438_2.00	Mus musculus	BSYWGGAATGY	RCATTCCWRSV	Misc Kulakovskiy et al.(2013) TEAD1_MOUSE.H11MO.0.A	0.717	0.717
Tead2 M09437_2.00	Mus musculus	SCWGGAATGYNN	NNRCATTCCWGS	Misc Kulakovskiy et al.(2013) TEAD2_MOUSE.H11MO.0.C	0.717	0.717
Tead2 M09653_2.00	Mus musculus	BCWGGAATGY	RCATTCCWGV	Misc Heinz et al.(2010) Py2T-Tead2_GSE55709	0.717	0.717
TEAD2 M11403_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$ETF_Q6_01	0.717	0.717
TEAD1 M11404_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$TEF_01	0.717	0.717
TEAD1 M11405_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$TEF_07	0.717	0.717
TEAD1 M11406_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$TEF1_Q6_03	0.717	0.717
TEAD1 M11407_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$TEF1_Q6_04	0.717	0.717
TEAD1 M11408_2.00	Homo sapiens	Transfac license required	Transfac license required	Transfac Matys et al.(2006) V$TEF1_Q6	0.717	0.717
TEAD1 M05826_2.00	Homo sapiens	HGGWATGYN	NRCATWCCD	SELEX Yin et al.(2017) TEAD1_FL_Methyl-HT-SELEX	0.717	0.717
TEAD2 M05824_2.00	Homo sapiens	NHGGAATGYR	YRCATTCCDN	SELEX Yin et al.(2017) TEAD2_FL_Methyl-HT-SELEX	0.717	0.717
For this family, TFs with SR scores > 0.700* will likely have a similar motif*