THI2 (Saccharomyces cerevisiae)
Zinc cluster

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00172 (Zn_clus) IPR001138 YBR240C T388334_2.00 Ensembl (2018-Dec-8) Link out
NCBI Gene Info:
Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of thiamine biosynthetic process and positive regulation of transcription by RNA polymerase II. Located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
THI2
M08467_2.00		 Saccharomyces cerevisiae
GGMAACYSWWAGARC
GYTCTWWSRGTTKCC		 COMPILED
Mathelier et al.(2014)
MA0407.1		 (Direct) (Direct)
THI2
M08647_2.00		 Saccharomyces cerevisiae
NMNKNNNBNNBBNNNNCCGH
DCGGNNNNVVNNVNNNMNKN		 Misc
DeBoer et al.(2011)
YBR240C_1449		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
For this family, TFs with SR scores > 0.537 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
YBR240C Zinc cluster 28 66

Links

Other Zinc cluster family TFs
Other Saccharomyces cerevisiae TFs

23 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
1967_YBR240C Saccharomyces paradoxus 1967_YBR240C I 0.683
4848_YBR240C Saccharomyces mikatae 4848_YBR240C I 0.683
SKUD_138702 Saccharomyces kudriavzevii SKUD_138702 I 0.683
SU7_0277 Saccharomyces arboricola SU7_0277 I 0.683
2117_YBR240C Saccharomyces bayanus 2117_YBR240C I 0.654
KAFR_0G03520 Kazachstania africana KAFR_0G03520 I 0.620
Ecym_2263 Eremothecium cymbalariae Ecym_2263 I 0.619
SAKL0A06072g Lachancea kluyveri SAKL0A06072g I 0.619
KLLA0_F10373g Kluyveromyces lactis KLLA0_F10373g I 0.611
ZYRO0G21626g Zygosaccharomyces rouxii ZYRO0G21626g I 0.610
Kwal_1631 Kluyveromyces waltii Kwal_1631 I 0.604
NDAI_0F02050 Naumovozyma dairenensis NDAI_0F02050 I 0.604
NCAS_0H01240 Naumovozyma castellii NCAS_0H01240 I 0.603
Scas_Contig597.4 Saccharomyces castellii Scas_Contig597.4 I 0.603
TDEL_0B04000 Torulaspora delbrueckii TDEL_0B04000 I 0.601
KLTH0H05720g Kluyveromyces thermotolerans KLTH0H05720g I 0.586
KLTH0H05720g Lachancea thermotolerans KLTH0H05720g I 0.586
Kpol_534p28 Vanderwaltozyma polyspora Kpol_534p28 I 0.586
LALA0_S13e03268g Lachancea lanzarotensis LALA0_S13e03268g I 0.584
AGOS_AFL033W Ashbya gossypii AGOS_AFL033W I 0.584
AACERI_AaceriAFL033W Saccharomycetaceae sp ashbya aceri AACERI_AaceriAFL033W I 0.584
ZBAI_04285 Zygosaccharomyces bailii ZBAI_04285 I 0.544
ZBAI_07794 Zygosaccharomyces bailii ZBAI_07794 I 0.544