SREBF1 (Homo sapiens)
bHLH

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00010 (HLH) IPR001092 ENSG00000072310 T034251_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
SREBF1
M04062_2.00		 Homo sapiens
VHCACVCSAY
RTSGBGTGDB		 SELEX
Yin et al.(2017)
SREBF1_eDBD_HT-SELEX_1		 (Direct) (Direct)
SREBF1
M04063_2.00		 Homo sapiens
VHCRCGYGDB
VHCRCGYGDB		 SELEX
Yin et al.(2017)
SREBF1_eDBD_HT-SELEX_2		 (Direct) (Direct)
SREBF1
M04064_2.00		 Homo sapiens
MTCACVCCAY
RTGGBGTGAK		 SELEX
Yin et al.(2017)
SREBF1_eDBD_Methyl-HT-SELEX_1		 (Direct) (Direct)
SREBF1
M04065_2.00		 Homo sapiens
RTCACCTGAY
RTCAGGTGAY		 SELEX
Yin et al.(2017)
SREBF1_eDBD_Methyl-HT-SELEX_2		 (Direct) (Direct)
SREBF1
M08048_2.00		 Homo sapiens
VTCACSCCAY
RTGGSGTGAB		 ChIP-seq
Mathelier et al.(2014)
MA0595.1		 (Direct) (Direct)
SREBF1
M08711_2.00		 Homo sapiens
VTCACVYSAYH
DRTSRBGTGAB		 Misc
Kulakovskiy et al.(2013)
SRBP1_HUMAN.H11MO.0.A		 (Direct) (Direct)
SREBF1
M09796_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SREBF1_02		 (Direct) (Direct)
SREBF1
M09797_2.00		 Homo sapiens
NATCACGTGAB
VTCACGTGATN		 Transfac
Matys et al.(2006)
V$SREBP1_01		 (Direct) (Direct)
SREBF1
M09798_2.00		 Homo sapiens
KRTCACCCCAC
GTGGGGTGAYM		 Transfac
Matys et al.(2006)
V$SREBP1_02		 (Direct) (Direct)
SREBF1
M09799_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SREBP1_Q5		 (Direct) (Direct)
SREBF1
M09800_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SREBP1_Q6_01		 (Direct) (Direct)
SREBF1
M09801_2.00		 Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SREBP1_Q6		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Srebf1
M00754_2.00 		Mus musculus
VWCAYVYSAB
VTSRBRTGWB		 PBM
Weirauch et al.(2013)
pTH0914 		0.914 0.980
Srebf1
M01724_2.00 		Mus musculus
RWCAYVYBD
HVRBRTGWY		 PBM
Weirauch et al.(2014)
pTH5161 		0.914 0.980
Srebf1
M02816_2.00 		Mus musculus
RTCACGTGAY
RTCACGTGAY		 SELEX
Jolma et al.(2013)
Srebf1_1 		0.914 0.980
Srebf1
M08749_2.00 		Mus musculus
VTCASSYSABN
NVTSRSSTGAB		 Misc
Kulakovskiy et al.(2013)
SRBP1_MOUSE.H11MO.0.B 		0.914 0.980
HLH106
M03626_2.00 		Drosophila melanogaster
RTCACGTGAY
RTCACGTGAY		 SELEX
Nitta et al.(2015)
HLH106_1 		0.890 0.804
HLH106
M03627_2.00 		Drosophila melanogaster
NRTCACGCCAYH
DRTGGCGTGAYN		 SELEX
Nitta et al.(2015)
HLH106_2 		0.890 0.804
Srebf2
M01725_2.00 		Mus musculus
TSRCGTGA
TCACGYSA		 PBM
Weirauch et al.(2014)
pTH4327 		0.862 0.804
SREBF2
M02811_2.00 		Homo sapiens
RTCACGTGAY
RTCACGTGAY		 SELEX
Jolma et al.(2013)
SREBF2_1 		0.862 0.804
SREBF2
M03591_2.00 		Homo sapiens
NRTCACVCCAYH
DRTGGBGTGAYN		 SELEX
Nitta et al.(2015)
SREBF2_1 		0.862 0.804
SREBF2
M04219_2.00 		Homo sapiens
RTCACGCCAY
RTGGCGTGAY		 SELEX
Yin et al.(2017)
SREBF2_eDBD_HT-SELEX_1 		0.862 0.804
SREBF2
M04220_2.00 		Homo sapiens
ATCACGTGAY
RTCACGTGAT		 SELEX
Yin et al.(2017)
SREBF2_eDBD_HT-SELEX_2 		0.862 0.804
SREBF2
M08059_2.00 		Homo sapiens
RTCACVCCAB
VTGGBGTGAY		 ChIP-seq
Mathelier et al.(2014)
MA0596.1 		0.862 0.804
SREBF2
M08741_2.00 		Homo sapiens
NNYCWSBCCABBB
VVVTGGVSWGRNN		 Misc
Kulakovskiy et al.(2013)
SRBP2_HUMAN.H11MO.0.B 		0.862 0.804
Srebf2
M08752_2.00 		Mus musculus
NNYCWSBCCABBB
VVVTGGVSWGRNN		 Misc
Kulakovskiy et al.(2013)
SRBP2_MOUSE.H11MO.0.B 		0.862 0.804
SREBF2
M09462_2.00 		Homo sapiens
MNRTCACVCCAC
GTGGBGTGAYNK		 Misc
Heinz et al.(2010)
HepG2-Srebp2_GSE31477 		0.862 0.804
SREBF2
M09882_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SREBP2_Q6_01 		0.862 0.804
SREBF2
M09883_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SREBP2_Q6 		0.862 0.804
SREBF2
M04221_2.00 		Homo sapiens
RTCACVCCAY
RTGGBGTGAY		 SELEX
Yin et al.(2017)
SREBF2_eDBD_Methyl-HT-SELEX_1 		0.862 0.804
SREBF2
M04222_2.00 		Homo sapiens
RTCACSTGAY
RTCASGTGAY		 SELEX
Yin et al.(2017)
SREBF2_eDBD_Methyl-HT-SELEX_2 		0.862 0.804
For this family, TFs with SR scores > 0.838 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000261646 bHLH 324 374
ENSP00000348069 bHLH 354 404
ENSP00000379100 bHLH 70 120
ENSP00000379106 bHLH 70 120
ENSP00000411516 bHLH 298 325

Links

Other bHLH family TFs
Other Homo sapiens TFs

211 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
AAEL001230 Aedes aegypti AAEL001230 N 0.000
Aan_R008628 Calypte anna Aan_R008628 N 0.000
AARA002561 Anopheles arabiensis AARA002561 N 0.000
ACUA023712 Anopheles culicifacies ACUA023712 N 0.000
ADIR004650 Anopheles dirus ADIR004650 N 0.000
Afo_R015783 Aptenodytes forsteri Afo_R015783 N 0.000
AFUN000252 Anopheles funestus AFUN000252 N 0.000
AGAP000875 Anopheles gambiae AGAP000875 N 0.000
Alligator_sinensis_CCG018588.1 Alligator sinensis Alligator_sinensis_CCG018588.1 N 0.000
AMEC011182 Anopheles melas AMEC011182 N 0.000
AMIN005800 Anopheles minimus AMIN005800 N 0.000
AQUA002448 Anopheles quadriannulatus AQUA002448 N 0.000
ASIS023610 Anopheles sinensis ASIS023610 N 0.000
Cmyd_10014849 Chelonia mydas Cmyd_10014849 N 0.000
D917_04267 Trichinella nativa D917_04267 N 0.000
D918_01045 Trichuris suis D918_01045 N 0.000
ENSAMXG00000013895 Astyanax mexicanus ENSAMXG00000013895 N 0.000
ENSBTAP00000004603-D1 Bos grunniens ENSBTAP00000004603-D1 N 0.000
ENSCSAG00000006922 Chlorocebus sabaeus ENSCSAG00000006922 N 0.000
MYT1L Dasypus novemcinctus ENSDNOG00000037275 N 0.000
ENSFALG00000002053 Ficedula albicollis ENSFALG00000002053 N 0.000
ENSGACG00000012816 Gasterosteus aculeatus ENSGACG00000012816 N 0.000
MYT1L Gorilla gorilla ENSGGOG00000026335 N 0.000
ENSGMOG00000000679 Gadus morhua ENSGMOG00000000679 N 0.000
ENSGMOG00000006285 Gadus morhua ENSGMOG00000006285 N 0.000
ENSGMOG00000009083 Gadus morhua ENSGMOG00000009083 N 0.000
ENSGMOG00000012782 Gadus morhua ENSGMOG00000012782 N 0.000
ENSLACG00000014372 Latimeria chalumnae ENSLACG00000014372 N 0.000
MYT1L Loxodonta africana ENSLAFG00000002751 N 0.000
ENSLAFG00000004212 Loxodonta africana ENSLAFG00000004212 N 0.000
ENSLOCG00000017216 Lepisosteus oculatus ENSLOCG00000017216 N 0.000
ENSMEUG00000001386 Macropus eugenii ENSMEUG00000001386 N 0.000
ST18 Microcebus murinus ENSMICG00000003705 N 0.000
Myt1 Mus musculus ENSMUSG00000010505 N 0.000
MYT1L Oryctolagus cuniculus ENSOCUG00000016764 N 0.000
MYT1L Otolemur garnettii ENSOGAG00000010219 N 0.000
ENSONIG00000011665 Oreochromis niloticus ENSONIG00000011665 N 0.000
ENSONIG00000018694 Oreochromis niloticus ENSONIG00000018694 N 0.000
ST18 Oryzias latipes ENSORLG00000017500 N 0.000
MYT1L Oryzias latipes ENSORLG00000017852 N 0.000
myt1a Oryzias latipes ENSORLG00000020139 N 0.000
ST18 Procavia capensis ENSPCAG00000014437 N 0.000
ENSPFOG00000005354 Poecilia formosa ENSPFOG00000005354 N 0.000
ENSPFOG00000017045 Poecilia formosa ENSPFOG00000017045 N 0.000
ENSSHAG00000015433 Sarcophilus harrisii ENSSHAG00000015433 N 0.000
ENSSTOG00000016500 Ictidomys tridecemlineatus ENSSTOG00000016500 N 0.000
MYT1 Takifugu rubripes ENSTRUG00000002124 N 0.000
MYT1L Takifugu rubripes ENSTRUG00000003414 N 0.000
ST18 Takifugu rubripes ENSTRUG00000006078 N 0.000
myt1la Takifugu rubripes ENSTRUG00000015790 N 0.000
ENSTSYG00000008880 Tarsius syrichta ENSTSYG00000008880 N 0.000
Gfo_R002934 Geospiza fortis Gfo_R002934 N 0.000
HMEL002385 Heliconius melpomene HMEL002385 N 0.000
Hsal_01303--XP_394358.3_APIME Harpegnathos saltator Hsal_01303--XP_394358.3_APIME N 0.000
Myotis_brandtii_MYT1L_10020908 Myotis brandtii Myotis_brandtii_MYT1L_10020908 N 0.000
NV11201 Nasonia vitripennis NV11201 N 0.000
Pvit_03612 Pogona vitticeps Pvit_03612 N 0.000
SMAR006962 Strigamia maritima SMAR006962 N 0.000
Tal_R003131 Tyto alba Tal_R003131 N 0.000