MLX (Homo sapiens)
bHLH

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00010 (HLH) IPR001092 ENSG00000108788 T034260_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
MLX
M02779_2.00		 Homo sapiens
RTCACGTGAY
RTCACGTGAY		 SELEX
Jolma et al.(2013)
MLX_1		 (Direct) (Direct)
MLX
M04080_2.00		 Homo sapiens
NCACGTGN
NCACGTGN		 SELEX
Yin et al.(2017)
MLX_eDBD_HT-SELEX		 (Direct) (Direct)
MLX
M04081_2.00		 Homo sapiens
NCACRTGV
BCAYGTGN		 SELEX
Yin et al.(2017)
MLX_eDBD_Methyl-HT-SELEX		 (Direct) (Direct)
MLX
M04082_2.00		 Homo sapiens
NVCACGTGVYN
NRBCACGTGBN		 SELEX
Yin et al.(2017)
MLX_FL_HT-SELEX		 (Direct) (Direct)
MLX
M04083_2.00		 Homo sapiens
NDBCACRTGBV
BVCAYGTGVHN		 SELEX
Yin et al.(2017)
MLX_FL_Methyl-HT-SELEX		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Mlx
M00752_2.00 		Mus musculus
CACGTGNNN
NNNCACGTG		 PBM
Weirauch et al.(2013)
pTH2882 		0.914 1.000
Mlx
M01721_2.00 		Mus musculus
NCRCGTGNNN
NNNCACGYGN		 PBM
Weirauch et al.(2014)
pTH5070 		0.914 1.000
Mlx
M02815_2.00 		Mus musculus
RTCACGTGAY
RTCACGTGAY		 SELEX
Jolma et al.(2013)
Mlx_1 		0.914 1.000
MLX
M01114_2.00 		Monodelphis domestica
NNNCACGTGN
NCACGTGNNN		 PBM
Lambert et al.(2019)
pTH11463 		0.914 0.982
For this family, TFs with SR scores > 0.838 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSP00000246912 bHLH 130 188
ENSP00000320913 bHLH 46 104
ENSP00000416627 bHLH 76 134
ENSP00000464697 bHLH 100 158

Links

Other bHLH family TFs
Other Homo sapiens TFs

52 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
ACRE_078720 Acremonium chrysogenum ACRE_078720 N
AFUA_4G03960 Aspergillus fumigatus CADAFUAG00001413 N
CADANGAG00011028 Aspergillus niger CADANGAG00011028 N
CH063_08271 Colletotrichum higginsianum CH063_08271 N
CMQ_1168 Grosmannia clavigera CMQ_1168 N
CSUB01_01897 Colletotrichum sublineola CSUB01_01897 N
CTHT_0034060 Chaetomium thermophilum CTHT_0034060 N
F503_04971 Ophiostoma piceae uamh F503_04971 N
FFUJ_12262 Fusarium fujikuroi FFUJ_12262 N
GSTUM_00009064001 Tuber melanosporum GSTUM_00009064001 N
H101_00195 Trichophyton interdigitale H101_00195 N
HCBG_07168 Histoplasma capsulatum HCBG_07168 N
LEMA_P057910.1 Leptosphaeria maculans LEMA_P057910.1 N
MCYG_02571 Microsporum canis MCYG_02571 N
MCYG_02571 Arthroderma otae MCYG_02571 N
NEUTE1DRAFT_145502 Neurospora tetrasperma NEUTE1DRAFT_145502 N
OIDMADRAFT_72735 Oidiodendron maius OIDMADRAFT_72735 N
PDIP_15270 Penicillium digitatum PDIP_15270 N
PV11_07762 Exophiala sideris PV11_07762 N
S40285_04014 Stachybotrys chlorohalonata S40285_04014 N
S40288_02610 Stachybotrys chartarum S40288_02610 N
SETTUDRAFT_155346 Setosphaeria turcica SETTUDRAFT_155346 N
SNOG_01738 Stagonospora nodorum SNOG_01738 N
SNOG_12765 Phaeosphaeria nodorum SNOG_12765 N
TEQG_05685 Trichophyton equinum TEQG_05685 N
TESG_07096 Trichophyton tonsurans TESG_07096 N
U727_00430311441 Penicillium solitum U727_00430311441 N
UV8b_3206 Ustilaginoidea virens UV8b_3206 N
V499_01312 Pseudogymnoascus pannorum V499_01312 N
VDAG_09033 Verticillium dahliae VDAG_09033 N
VDBG_04344 Verticillium albo atrum VDBG_04344 N
VDBG_04344 Verticillium alfalfae VDBG_04344 N
W97_05320 Coniosporium apollinis W97_05320 N