Gli3 (Mus musculus)
C2H2 ZF

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00096 (zf-C2H2) IPR007087 ENSMUSG00000021318 T101021_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Gli3
M01022_2.00		 Mus musculus
NGACCACCCNN
NNGGGTGGTCN		 PBM
Peterson et al.(2012)
Gli3		 (Direct) (Direct)
Gli3
M08023_2.00		 Mus musculus
RGVCCACCCAS
STGGGTGGBCY		 ChIP-seq
Chen et al.(2011)
GSE11062_Gli3		 (Direct) (Direct)
Gli3
M09512_2.00		 Mus musculus
RGACCACCCASR
YSTGGGTGGTCY		 Misc
Heinz et al.(2010)
Limb-GLI3_GSE11077		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
GLI3
M04416_2.00 		Homo sapiens
VGACCACCCACVNHG
CDNBGTGGGTGGTCB		 SELEX
Yin et al.(2017)
GLI3_eDBD_HT-SELEX 		0.781 0.983
GLI3
M02642_2.00 		Homo sapiens
GACCACCCANK
MNTGGGTGGTC		 SELEX
Hallikas et al.(2006)
GLI3 		0.781 0.983
GLI3
M08875_2.00 		Homo sapiens
VRACCACCCAV
BTGGGTGGTYB		 Misc
Kulakovskiy et al.(2013)
GLI3_HUMAN.H11MO.0.B 		0.781 0.983
GLI3
M10167_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$GLI3_01 		0.781 0.983
GLI3
M10168_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$GLI3_Q5_01 		0.781 0.983
GLI3
M04417_2.00 		Homo sapiens
CWHBGTGGGTGGTCY
RGACCACCCACVDWG		 SELEX
Yin et al.(2017)
GLI3_eDBD_Methyl-HT-SELEX 		0.781 0.983
Gli2
M01024_2.00 		Mus musculus
NGACCACCYN
NRGGTGGTCN		 PBM
Peterson et al.(2012)
Gli2 		0.761 0.930
GLI2
M02875_2.00 		Homo sapiens
GMCCACMCANVNHB
VDNBNTGKGTGGKC		 SELEX
Jolma et al.(2013)
GLI2_1 		0.761 0.930
GLI2
M02876_2.00 		Homo sapiens
GCGACCACVCWR
YWGBGTGGTCGC		 SELEX
Jolma et al.(2013)
GLI2_2 		0.761 0.930
GLI2
M02732_2.00 		Homo sapiens
GACCACMCAN
NTGKGTGGTC		 SELEX
Jolma et al.(2010)
GLI2_monomer 		0.761 0.930
GLI2
M04402_2.00 		Homo sapiens
VGACCACCCACVDHG
CDHBGTGGGTGGTCB		 SELEX
Yin et al.(2017)
GLI2_eDBD_HT-SELEX 		0.761 0.930
GLI2
M02641_2.00 		Homo sapiens
GACCACCCAHG
CDTGGGTGGTC		 SELEX
Hallikas et al.(2006)
GLI2 		0.761 0.930
GLI2
M10114_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$GLI2_Q3 		0.761 0.930
GLI2
M10115_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$GLI2_Q6 		0.761 0.930
GLI2
M04403_2.00 		Homo sapiens
RGACCACCCACVWWG
CWWBGTGGGTGGTCY		 SELEX
Yin et al.(2017)
GLI2_eDBD_Methyl-HT-SELEX 		0.761 0.930
For this family, TFs with SR scores > 0.755 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M01022_2.00 C2H2 ZF 16 41
M01022_2.00 C2H2 ZF 49 76
M01022_2.00 C2H2 ZF 82 106
M01022_2.00 C2H2 ZF 112 137
M01022_2.00 C2H2 ZF 143 168

DNA Binding Domains

Protein ID Domain From To Sequence
ENSMUSP00000106137 C2H2 ZF 480 505
ENSMUSP00000106137 C2H2 ZF 513 540
ENSMUSP00000106137 C2H2 ZF 546 570
ENSMUSP00000106137 C2H2 ZF 576 601
ENSMUSP00000106137 C2H2 ZF 607 632
ENSMUSP00000115989 C2H2 ZF 480 505
ENSMUSP00000115989 C2H2 ZF 513 540
ENSMUSP00000115989 C2H2 ZF 546 570
ENSMUSP00000115989 C2H2 ZF 576 596

Links

Other C2H2 ZF family TFs
Other Mus musculus TFs

139 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
A1O5_10470 Cladophialophora psammophila A1O5_10470 I 0.000
AGABI2DRAFT_187161 Agaricus bisporus AGABI2DRAFT_187161 N 0.000
AOL_s00097g585 Arthrobotrys oligospora AOL_s00097g585 I 0.000
AUEXF2481DRAFT_6481 Aureobasidium subglaciale AUEXF2481DRAFT_6481 I 0.000
BAUCODRAFT_276951 Baudoinia compniacensis BAUCODRAFT_276951 N 0.000
BBA_07483 Beauveria bassiana BBA_07483 N 0.000
Bcin03g00750 Botrytis cinerea Bcin03g00750 I 0.000
BDDG_03512 Blastomyces dermatitidis BDDG_03512 I 0.000
BN946_scf184845.g7 Trametes cinnabarina BN946_scf184845.g7 N 0.000
CC1G_05468 Coprinopsis cinerea CC1G_05468 N 0.000
CCM_08924 Cordyceps militaris CCM_08924 N 0.000
CERSUDRAFT_116811 Ceriporiopsis subvermispora CERSUDRAFT_116811 N 0.000
CGGC5_4259 Colletotrichum gloeosporioides CGGC5_4259 I 0.000
CIMG_13671 Coccidioides immitis CIMG_13671 I 0.000
CMQ_6538 Grosmannia clavigera CMQ_6538 I 0.000
CNJ00670 Cryptococcus neoformans CNJ00670 N 0.000
CPC735_010880 Coccidioides posadasii CPC735_010880 I 0.000
CPUR_06646 Claviceps purpurea CPUR_06646 I 0.000
CSUB01_10111 Colletotrichum sublineola CSUB01_10111 I 0.000
DICSQDRAFT_157861 Dichomitus squalens DICSQDRAFT_157861 N 0.000
E5Q_04000 Mixia osmundae E5Q_04000 N 0.000
EDP42441.1 Malassezia globosa EDP42441.1 N 0.000
estExt_fgenesh2_pm.C_100040 Heterobasidion annosum estExt_fgenesh2_pm.C_100040 N 0.000
estExt_Genewise1Plus.C_sca_8_chr1_1_00454 Nectria haematococca estExt_Genewise1Plus.C_sca_8_chr1_1_00454 I 0.000
EV44_g5365 Erysiphe necator EV44_g5365 I 0.000
fgenesh1_pg.C_scaffold_5000487 Phanerochaete chrysosporium fgenesh1_pg.C_scaffold_5000487 N 0.000
fgeneshMC_pg.1_#_1636 Mucor circinelloides fgeneshMC_pg.1_#_1636 I 0.000
fgeneshMC_pg.4_#_1012 Mucor circinelloides fgeneshMC_pg.4_#_1012 N 0.000
fgeneshMC_pg.5_#_674 Mucor circinelloides fgeneshMC_pg.5_#_674 I 0.000
fgeneshPB_pg.28__99 Phycomyces blakesleeanus fgeneshPB_pg.28__99 N 0.000
FOMPIDRAFT_73073 Fomitopsis pinicola FOMPIDRAFT_73073 N 0.000
GALMADRAFT_139439 Galerina marginata GALMADRAFT_139439 N 0.000
GGTG_06418 Gaeumannomyces graminis GGTG_06418 I 0.000
GLOTRDRAFT_139856 Gloeophyllum trabeum GLOTRDRAFT_139856 N 0.000
GLRG_10296 Colletotrichum graminicola GLRG_10296 I 0.000
GSTUM_00008508001 Tuber melanosporum GSTUM_00008508001 I 0.000
H072_2778 Dactylellina haptotyla H072_2778 I 0.000
HCBG_01276 Histoplasma capsulatum HCBG_01276 I 0.000
HMPREF1624_07934 Sporothrix schenckii HMPREF1624_07934 I 0.000
J056_002242 Wallemia ichthyophaga J056_002242 N 0.000
K443DRAFT_109004 Laccaria amethystina K443DRAFT_109004 N 0.000
L804_00066 Cryptococcus gattii L804_00066 N 0.000
M378DRAFT_24342 Amanita muscaria M378DRAFT_24342 N 0.000
M407DRAFT_17372 Tulasnella calospora M407DRAFT_17372 N 0.000
M437DRAFT_37789 Aureobasidium melanogenum M437DRAFT_37789 I 0.000
M438DRAFT_349765 Aureobasidium pullulans M438DRAFT_349765 I 0.000
M7I_0147 Glarea lozoyensis M7I_0147 I 0.000
MAPG_04630 Magnaporthe poae MAPG_04630 I 0.000
MGG_03288 Magnaporthe oryzae MGG_03288 I 0.000
Moror_12097 Moniliophthora roreri Moror_12097 N 0.000
NechaG65174 Fusarium solani NechaG65174 I 0.000
OCS_04625 Ophiocordyceps sinensis OCS_04625 I 0.000
OIDMADRAFT_183172 Oidiodendron maius OIDMADRAFT_183172 I 0.000
PAAG_12580 Paracoccidioides sp lutzii PAAG_12580 I 0.000
PABG_06099 Paracoccidioides brasiliensis PABG_06099 I 0.000
PaG_04268 Pseudozyma aphidis PaG_04268 N 0.000
PAN0_143c6805 Pseudozyma antarctica PAN0_143c6805 N 0.000
PAXRUDRAFT_536199 Paxillus rubicundulus PAXRUDRAFT_536199 N 0.000
PFICI_09118 Pestalotiopsis fici PFICI_09118 I 0.000
PGTG_14882 Puccinia graminis PGTG_14882 N 0.000
PHACADRAFT_253478 Phanerochaete carnosa PHACADRAFT_253478 N 0.000
PHLGIDRAFT_33148 Phlebiopsis gigantea PHLGIDRAFT_33148 N 0.000
PHSY_004982 Pseudozyma hubeiensis PHSY_004982 N 0.000
PILCRDRAFT_816838 Piloderma croceum PILCRDRAFT_816838 N 0.000
PISMIDRAFT_21810 Pisolithus microcarpus PISMIDRAFT_21810 N 0.000
PTTG_06755 Puccinia triticina PTTG_06755 N 0.000
PV05_07253 Exophiala xenobiotica PV05_07253 I 0.000
PV11_03612 Exophiala sideris PV11_03612 I 0.000
PVAR5_7895 Byssochlamys spectabilis PVAR5_7895 I 0.000
RO3G_01852 Rhizopus oryzae RO3G_01852 N 0.000
RO3G_03650 Rhizopus oryzae RO3G_03650 N 0.000
RO3G_15999 Rhizopus oryzae RO3G_15999 N 0.000
SAPIO_CDS1137 Scedosporium apiospermum SAPIO_CDS1137 I 0.000
SCLCIDRAFT_1207899 Scleroderma citrinum SCLCIDRAFT_1207899 N 0.000
SNOG_02426 Stagonospora nodorum SNOG_02426 I 0.000
SNOG_02426 Phaeosphaeria nodorum SNOG_02426 I 0.000
SPBR_00337 Sporothrix brasiliensis SPBR_00337 I 0.000
sr16828 Sporisorium reilianum sr16828 N 0.000
SS1G_00829 Sclerotinia sclerotiorum SS1G_00829 I 0.000
TRIATDRAFT_141284 Trichoderma atroviride TRIATDRAFT_141284 I 0.000
TRIREDRAFT_22532 Trichoderma reesei TRIREDRAFT_22532 I 0.000
TRIVIDRAFT_2765 Trichoderma virens TRIVIDRAFT_2765 I 0.000
UM06385 Ustilago maydis UM06385 N 0.000
UV8b_475 Ustilaginoidea virens UV8b_475 I 0.000
V565_084030 Rhizoctonia solani V565_084030 N 0.000
VDAG_07716 Verticillium dahliae VDAG_07716 I 0.000
VDBG_05782 Verticillium alfalfae VDBG_05782 I 0.000
VDBG_05782 Verticillium albo atrum VDBG_05782 I 0.000
VHEMI01778 Torrubiella hemipterigena VHEMI01778 N 0.000
WALSEDRAFT_59486 Wallemia sebi WALSEDRAFT_59486 N 0.000