SIX3 (Bos taurus)
Homeodomain

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00046 (Homeobox) IPR001356 ENSBTAG00000027017 T207524_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Six3
M00483_2.00 		Mus musculus
NNNAYMN
NKRTNNN		 PBM
Berger et al.(2008)
Six3_1732 		0.867 1.000
SIX3
M05159_2.00 		Homo sapiens
NNYGATABBN
NVVTATCRNN		 SELEX
Yin et al.(2017)
SIX3_eDBD_HT-SELEX 		0.867 1.000
SIX3
M10698_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SIX3_Q6 		0.867 1.000
SIX3
M05160_2.00 		Homo sapiens
NNYGATABVB
VBVTATCRNN		 SELEX
Yin et al.(2017)
SIX3_eDBD_Methyl-HT-SELEX 		0.867 1.000
Optix
M02124_2.00 		Drosophila melanogaster
NNNNNDATMN
NKATHNNNNN		 PBM
Weirauch et al.(2014)
pTH5437 		0.867 0.947
Optix
M03850_2.00 		Drosophila melanogaster
TAATYTAATTA
TAATTARATTA		 SELEX
Nitta et al.(2015)
Optix_1 		0.867 0.947
Optix
M06526_2.00 		Drosophila melanogaster
TGATA
TATCA		 B1H
Mathelier et al.(2014)
MA0199.1 		0.867 0.947
Optix
M06327_2.00 		Drosophila melanogaster
HHVTGATA
TATCABDD		 B1H
Zhu et al.(2011)
Optix_Cell_FBgn0025360 		0.867 0.947
Optix
M06328_2.00 		Drosophila melanogaster
NNNTGATA
TATCANNN		 B1H
Zhu et al.(2011)
Optix_SOLEXA_FBgn0025360 		0.867 0.947
SIX6
M00326_2.00 		Homo sapiens
NNDATMB
VKATHNN		 PBM
Barrera et al.(2016)
SIX6_REF 		0.865 0.982
Six6
M00169_2.00 		Mus musculus
NNAYMNN
NNKRTNN		 PBM
Badis et al.(2009)
Six6_2267 		0.865 0.982
Six6
M00412_2.00 		Mus musculus
NNNTGATAYCN
NGRTATCANNN		 PBM
Berger et al.(2008)
Six6_2267 		0.865 0.982
SIX6
M05357_2.00 		Homo sapiens
NNYGATASVB
VBSTATCRNN		 SELEX
Yin et al.(2017)
SIX6_eDBD_HT-SELEX 		0.865 0.982
SIX6
M00325_2.00 		Homo sapiens
NNNDATMB
VKATHNNN		 PBM
Barrera et al.(2016)
SIX6_H141N 		0.865 0.982
SIX6
M05358_2.00 		Homo sapiens
VBVYAYCRNN
NNYGRTRBVB		 SELEX
Yin et al.(2017)
SIX6_eDBD_Methyl-HT-SELEX 		0.865 0.982
six3
M02102_2.00 		Oryzias latipes
NNDAYMBNNN
NNNVKRTHNN		 PBM
Weirauch et al.(2014)
pTH5928 		0.865 0.947
SIX6
M00327_2.00 		Homo sapiens
NHDAYMBNN
NNVKRTHDN		 PBM
Barrera et al.(2016)
SIX6_T165A 		0.859 0.965
For this family, TFs with SR scores > 0.599 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSBTAP00000038493 Homeodomain 203 259

Links

Other Homeodomain family TFs
Other Bos taurus TFs

296 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
AAEL002321 Aedes aegypti AAEL002321 I 0.000
AALB006354 Anopheles albimanus AALB006354 I 0.000
AALB006643 Anopheles albimanus AALB006643 I 0.000
AARA001110 Anopheles arabiensis AARA001110 I 0.000
AARA001115 Anopheles arabiensis AARA001115 I 0.000
AATE014626 Anopheles atroparvus AATE014626 I 0.000
ACHR008920 Anopheles christyi ACHR008920 I 0.000
ACHR009845 Anopheles christyi ACHR009845 I 0.000
ACUA016154 Anopheles culicifacies ACUA016154 I 0.000
ACUA021227 Anopheles culicifacies ACUA021227 I 0.000
ACYPI008177 Acyrthosiphon pisum ACYPI008177 I 0.000
ACYPI067710 Acyrthosiphon pisum ACYPI067710 I 0.000
ADAC001560 Anopheles darlingi ADAC001560 I 0.000
ADAC003449 Anopheles darlingi ADAC003449 I 0.000
ADIR000968 Anopheles dirus ADIR000968 I 0.000
ADIR000973 Anopheles dirus ADIR000973 I 0.000
AEPI005798 Anopheles epiroticus AEPI005798 I 0.000
AEPI005803 Anopheles epiroticus AEPI005803 I 0.000
AFAF009619 Anopheles farauti AFAF009619 I 0.000
AFAF017899 Anopheles farauti AFAF017899 I 0.000
Afo_R014630 Aptenodytes forsteri Afo_R014630 I 0.000
AFUN011570 Anopheles funestus AFUN011570 I 0.000
AFUN011575 Anopheles funestus AFUN011575 I 0.000
AGAP000063 Anopheles gambiae AGAP000063 I 0.000
AGAP000067 Anopheles gambiae AGAP000067 I 0.000
Alligator_sinensis_CCG012954.1 Alligator sinensis Alligator_sinensis_CCG012954.1 I 0.000
AMEC013051 Anopheles melas AMEC013051 I 0.000
AMEC021831 Anopheles melas AMEC021831 I 0.000
AMEM002691 Anopheles merus AMEM002691 I 0.000
AMIN002127 Anopheles minimus AMIN002127 I 0.000
AMIN002132 Anopheles minimus AMIN002132 I 0.000
AQUA008308 Anopheles quadriannulatus AQUA008308 I 0.000
AQUA008313 Anopheles quadriannulatus AQUA008313 I 0.000
ASIS012617 Anopheles sinensis ASIS012617 I 0.000
ASIS012967 Anopheles sinensis ASIS012967 I 0.000
ASTEI06200 Anopheles stephensi ASTEI06200 I 0.000
ASTEI06205 Anopheles stephensi ASTEI06205 I 0.000
A_05170 Schistosoma haematobium A_05170 I 0.000
BXY_1643500 Bursaphelenchus xylophilus BXY_1643500 I 0.000
CBN04513 Caenorhabditis brenneri CBN04513 I 0.000
Cflo_00481--XP_394648.3_APIME Camponotus floridanus Cflo_00481--XP_394648.3_APIME I 0.000
CGI_10027695 Crassostrea gigas CGI_10027695 I 0.000
Cmyd_10016391 Chelonia mydas Cmyd_10016391 I 0.000
CPIJ006390 Culex quinquefasciatus CPIJ006390 I 0.000
CPIJ006398 Culex quinquefasciatus CPIJ006398 I 0.000
CpipJ_CPIJ006390 Culex pipiens CpipJ_CPIJ006390 I 0.000
CpipJ_CPIJ006398 Culex pipiens CpipJ_CPIJ006398 I 0.000
CRE07226 Caenorhabditis remanei CRE07226 I 0.000
csin101119 Clonorchis sinensis csin101119 I 0.000
csin110224 Clonorchis sinensis csin110224 I 0.000
D915_07175 Fasciola hepatica D915_07175 I 0.000
D917_00854 Trichinella nativa D917_00854 I 0.000
D918_01592 Trichuris suis D918_01592 I 0.000
DAPPUDRAFT_249978 Daphnia pulex DAPPUDRAFT_249978 I 0.000
DAPPUDRAFT_249991 Daphnia pulex DAPPUDRAFT_249991 I 0.000
EFV57892 Trichinella spiralis EFV57892 I 0.000
PAX6 Anolis carolinensis ENSACAG00000002252 I 0.000
ENSAMEG00000006908 Ailuropoda melanoleuca ENSAMEG00000006908 I 0.000
ENSAMXG00000001228 Astyanax mexicanus ENSAMXG00000001228 I 0.000
ENSAMXG00000013008 Astyanax mexicanus ENSAMXG00000013008 I 0.000
PAX6 Bos taurus ENSBTAG00000004561 I 0.000
ENSCING00000006503 Ciona intestinalis ENSCING00000006503 I 0.000
PAX6 Callithrix jacchus ENSCJAG00000005942 I 0.000
PAX6 Cavia porcellus ENSCPOG00000007245 I 0.000
ENSCSAG00000005253 Chlorocebus sabaeus ENSCSAG00000005253 I 0.000
ENSCSAVG00000007987 Ciona savignyi ENSCSAVG00000007987 I 0.000
pax6b Danio rerio ENSDARG00000045936 I 0.000
pax6a Danio rerio ENSDARG00000103379 I 0.000
PAX6 Dasypus novemcinctus ENSDNOG00000000761 I 0.000
PAX6 Equus caballus ENSECAG00000021000 I 0.000
PAX6 Echinops telfairi ENSETEG00000002655 I 0.000
PAX6 Felis catus ENSFCAG00000007094 I 0.000
PAX6 Homo sapiens ENSG00000007372 D 0.000
ENSGACG00000002490 Gasterosteus aculeatus ENSGACG00000002490 I 0.000
pax6b Gasterosteus aculeatus ENSGACG00000016030 I 0.000
PAX6 Gallus gallus ENSGALG00000012123 I 0.000
PAX6 Gorilla gorilla ENSGGOG00000010246 I 0.000
ENSGMOG00000012304 Gadus morhua ENSGMOG00000012304 I 0.000
ENSGMOG00000019087 Gadus morhua ENSGMOG00000019087 I 0.000
ENSLACG00000015337 Latimeria chalumnae ENSLACG00000015337 I 0.000
PAX6 Loxodonta africana ENSLAFG00000015520 I 0.000
ENSLOCG00000004578 Lepisosteus oculatus ENSLOCG00000004578 I 0.000
ENSMEUG00000015900 Macropus eugenii ENSMEUG00000015900 I 0.000
PAX6 Microcebus murinus ENSMICG00000004089 I 0.000
PAX6 Myotis lucifugus ENSMLUG00000006517 I 0.000
PAX6 Macaca mulatta ENSMMUG00000016810 I 0.000
PAX6 Monodelphis domestica ENSMODG00000009611 I 0.000
ENSMPUG00000011295 Mustela putorius furo ENSMPUG00000011295 I 0.000
Pax6 Mus musculus ENSMUSG00000027168 D 0.000
ENSNLEG00000017888 Nomascus leucogenys ENSNLEG00000017888 I 0.000
PAX6 Ornithorhynchus anatinus ENSOANG00000015149 I 0.000
ENSOARG00000016191 Ovis aries ENSOARG00000016191 I 0.000
PAX6 Oryctolagus cuniculus ENSOCUG00000011075 I 0.000
PAX6 Otolemur garnettii ENSOGAG00000007857 I 0.000
ENSONIG00000004074 Oreochromis niloticus ENSONIG00000004074 I 0.000
ENSONIG00000005541 Oreochromis niloticus ENSONIG00000005541 I 0.000
PAX6 Ochotona princeps ENSOPRG00000001678 I 0.000
ENSORLG00000000847 Oryzias latipes ENSORLG00000000847 I 0.000
pax6b Oryzias latipes ENSORLG00000009913 I 0.000
ENSP00000368401-D1 Bos grunniens ENSP00000368401-D1 I 0.000
ENSP00000368424 Macaca fascicularis ENSP00000368424 I 0.000
ENSPANG00000005448 Papio anubis ENSPANG00000005448 I 0.000
PAX6 Procavia capensis ENSPCAG00000005165 I 0.000
ENSPFOG00000016987 Poecilia formosa ENSPFOG00000016987 I 0.000
ENSPPYG00000003386 Pongo abelii ENSPPYG00000003386 I 0.000
ENSPSIG00000012748 Pelodiscus sinensis ENSPSIG00000012748 I 0.000
PAX6 Pan troglodytes ENSPTRG00000003474 I 0.000
Pax6 Rattus norvegicus ENSRNOG00000004410 I 0.000
PAX6 Sorex araneus ENSSARG00000011424 I 0.000
ENSSHAG00000016310 Sarcophilus harrisii ENSSHAG00000016310 I 0.000
PAX6 Sus scrofa ENSSSCG00000013320 I 0.000
ENSSTOG00000003211 Ictidomys tridecemlineatus ENSSTOG00000003211 I 0.000
PAX6 Tupaia belangeri ENSTBEG00000004748 I 0.000
ENSTNIG00000002471 Tetraodon nigroviridis ENSTNIG00000002471 I 0.000
pax6b Tetraodon nigroviridis ENSTNIG00000013804 I 0.000
pax6b Takifugu rubripes ENSTRUG00000006935 I 0.000
ENSTRUG00000017375 Takifugu rubripes ENSTRUG00000017375 I 0.000
ENSTSYG00000011965 Tarsius syrichta ENSTSYG00000011965 I 0.000
ENSXMAG00000014260 Xiphophorus maculatus ENSXMAG00000014260 I 0.000
ENSXMAG00000016421 Xiphophorus maculatus ENSXMAG00000016421 I 0.000
ey Drosophila melanogaster FBgn0005558 D 0.000
ey Drosophila pseudoobscura FBgn0018538 I 0.000
toy Drosophila melanogaster FBgn0019650 D 0.000
ey Drosophila virilis FBgn0028754 I 0.000
ey Drosophila persimilis FBgn0043659 I 0.000
ey Drosophila sechellia FBgn0068720 I 0.000
GF21877 Drosophila ananassae FBgn0098877 I 0.000
GF22818 Drosophila ananassae FBgn0099812 I 0.000
GG16399 Drosophila erecta FBgn0108631 I 0.000
GG16402 Drosophila erecta FBgn0108634 I 0.000
GH23963 Drosophila grimshawi FBgn0131420 I 0.000
GI14042 Drosophila mojavensis FBgn0136796 I 0.000
GI14081 Drosophila mojavensis FBgn0136835 I 0.000
GL17563 Drosophila persimilis FBgn0155166 I 0.000
GM13021 Drosophila sechellia FBgn0167952 I 0.000
GD24416 Drosophila simulans FBgn0195753 I 0.000
GJ13300 Drosophila virilis FBgn0200526 I 0.000
GK13683 Drosophila willistoni FBgn0215691 I 0.000
GK13702 Drosophila willistoni FBgn0215710 I 0.000
GE14559 Drosophila yakuba FBgn0232158 I 0.000
GE14563 Drosophila yakuba FBgn0232162 I 0.000
GA27636 Drosophila pseudoobscura FBgn0249001 I 0.000
fgenesh2_pg.scaffold_199000043 Branchiostoma floridae fgenesh2_pg.scaffold_199000043 I 0.000
GB41504 Apis mellifera GB41504 I 0.000
GB50342 Apis mellifera GB50342 I 0.000
HelroG173449 Helobdella robusta HelroG173449 I 0.000
HelroG80374 Helobdella robusta HelroG80374 I 0.000
Hsal_09597--XP_394648.3_APIME Harpegnathos saltator Hsal_09597--XP_394648.3_APIME I 0.000
ISCW021772 Ixodes scapularis ISCW021772 I 0.000
L596_g12356 Steinernema carpocapsae L596_g12356 I 0.000
L798_00712 Zootermopsis nevadensis L798_00712 I 0.000
L798_11483 Zootermopsis nevadensis L798_11483 I 0.000
L892_g3713 Steinernema scapterisci L892_g3713 I 0.000
LLOJ005149 Lutzomyia longipalpis LLOJ005149 I 0.000
LotgiG133720 Lottia gigantea LotgiG133720 I 0.000
MCINX016249 Melitaea cinxia MCINX016249 I 0.000
MCOS_0000220101 Mesocestoides corti MCOS_0000220101 I 0.000
NV15820 Nasonia vitripennis NV15820 I 0.000
NV17076 Nasonia vitripennis NV17076 I 0.000
Ogr12767 Ophisaurus gracilis Ogr12767 I 0.000
PHUM097050 Pediculus humanus PHUM097050 I 0.000
PTRK_0000512100 Parastrongyloides trichosuri PTRK_0000512100 I 0.000
Pvit_09512 Pogona vitticeps Pvit_09512 I 0.000
RSKR_0000862000 Rhabditophanes kr3021 RSKR_0000862000 I 0.000
Sakowv30026828m.g Saccoglossus kowalevskii Sakowv30026828m.g I 0.000
SMAR013763 Strigamia maritima SMAR013763 I 0.000
Smp_160670 Schistosoma mansoni Smp_160670 I 0.000
Smp_170750 Schistosoma mansoni Smp_170750 I 0.000
SMTD_0000837201 Schistosoma mattheei SMTD_0000837201 I 0.000
SMU15027897 Schmidtea mediterranea SMU15027897 I 0.000
SPAL_0001466800 Strongyloides papillosus SPAL_0001466800 I 0.000
SSTP_0001059400 Strongyloides stercoralis SSTP_0001059400 I 0.000
SVE_0819200 Strongyloides venezuelensis SVE_0819200 I 0.000
T265_09221 Opisthorchis viverrini T265_09221 I 0.000
T265_14971 Opisthorchis viverrini T265_14971 I 0.000
TC007409 Tribolium castaneum TC007409 I 0.000
TC008176 Tribolium castaneum TC008176 I 0.000
tetur09g00660 Tetranychus urticae tetur09g00660 I 0.000
TMUE_s0038005250 Trichuris muris TMUE_s0038005250 I 0.000
TTRE_0000173501 Trichuris trichiura TTRE_0000173501 I 0.000
vab-3 Caenorhabditis elegans WBGene00006870 I 0.000
pax6 Xenopus tropicalis XB-GENE-484088 I 0.000
pax6.S Xenopus laevis XB-GENE-6464331 I 0.000
pax6.L Xenopus laevis XB-GENE-865046 I 0.000