SIX6 (Choloepus hoffmanni)
Homeodomain

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00046 (Homeobox) IPR001356 ENSCHOG00000008045 T207781_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
SIX6
M00326_2.00 		Homo sapiens
NNDATMB
VKATHNN		 PBM
Barrera et al.(2016)
SIX6_REF 		0.867 1.000
Six6
M00169_2.00 		Mus musculus
NNAYMNN
NNKRTNN		 PBM
Badis et al.(2009)
Six6_2267 		0.867 1.000
Six6
M00412_2.00 		Mus musculus
NNNTGATAYCN
NGRTATCANNN		 PBM
Berger et al.(2008)
Six6_2267 		0.867 1.000
SIX6
M05357_2.00 		Homo sapiens
NNYGATASVB
VBSTATCRNN		 SELEX
Yin et al.(2017)
SIX6_eDBD_HT-SELEX 		0.867 1.000
SIX6
M05358_2.00 		Homo sapiens
VBVYAYCRNN
NNYGRTRBVB		 SELEX
Yin et al.(2017)
SIX6_eDBD_Methyl-HT-SELEX 		0.867 1.000
Six3
M00483_2.00 		Mus musculus
NNNAYMN
NKRTNNN		 PBM
Berger et al.(2008)
Six3_1732 		0.865 0.982
SIX3
M05159_2.00 		Homo sapiens
NNYGATABBN
NVVTATCRNN		 SELEX
Yin et al.(2017)
SIX3_eDBD_HT-SELEX 		0.865 0.982
SIX3
M10698_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$SIX3_Q6 		0.865 0.982
SIX6
M00325_2.00 		Homo sapiens
NNNDATMB
VKATHNNN		 PBM
Barrera et al.(2016)
SIX6_H141N 		0.865 0.982
SIX3
M05160_2.00 		Homo sapiens
NNYGATABVB
VBVTATCRNN		 SELEX
Yin et al.(2017)
SIX3_eDBD_Methyl-HT-SELEX 		0.865 0.982
six3
M02102_2.00 		Oryzias latipes
NNDAYMBNNN
NNNVKRTHNN		 PBM
Weirauch et al.(2014)
pTH5928 		0.865 0.947
Optix
M02124_2.00 		Drosophila melanogaster
NNNNNDATMN
NKATHNNNNN		 PBM
Weirauch et al.(2014)
pTH5437 		0.865 0.930
Optix
M03850_2.00 		Drosophila melanogaster
TAATYTAATTA
TAATTARATTA		 SELEX
Nitta et al.(2015)
Optix_1 		0.865 0.930
Optix
M06526_2.00 		Drosophila melanogaster
TGATA
TATCA		 B1H
Mathelier et al.(2014)
MA0199.1 		0.865 0.930
Optix
M06327_2.00 		Drosophila melanogaster
HHVTGATA
TATCABDD		 B1H
Zhu et al.(2011)
Optix_Cell_FBgn0025360 		0.865 0.930
Optix
M06328_2.00 		Drosophila melanogaster
NNNTGATA
TATCANNN		 B1H
Zhu et al.(2011)
Optix_SOLEXA_FBgn0025360 		0.865 0.930
SIX6
M00327_2.00 		Homo sapiens
NHDAYMBNN
NNVKRTHDN		 PBM
Barrera et al.(2016)
SIX6_T165A 		0.860 0.982
For this family, TFs with SR scores > 0.599 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
ENSCHOP00000007114 Homeodomain 190 246

Links

Other Homeodomain family TFs
Other Choloepus hoffmanni TFs

296 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
Aan_R012086 Calypte anna Aan_R012086 N 0.000
ACHR008952 Anopheles christyi ACHR008952 I 0.000
AEPI008594 Anopheles epiroticus AEPI008594 I 0.000
Afo_R008073 Aptenodytes forsteri Afo_R008073 N 0.000
AGAP000512 Anopheles gambiae AGAP000512 I 0.000
Alligator_sinensis_CCG011289.1 Alligator sinensis Alligator_sinensis_CCG011289.1 I 0.000
Alligator_sinensis_CCG020461.1 Alligator sinensis Alligator_sinensis_CCG020461.1 I 0.000
ALUE_0001723601 Ascaris lumbricoides ALUE_0001723601 N 0.000
Aqu1.216869 Amphimedon queenslandica Aqu1.216869 I 0.000
BGIBMGA001129 Bombyx mori BGIBMGA001129 I 0.000
Brh_R000244 Buceros rhinoceros Brh_R000244 N 0.000
CPIJ013490 Culex quinquefasciatus CPIJ013490 I 0.000
CpipJ_CPIJ013490 Culex pipiens CpipJ_CPIJ013490 I 0.000
D917_06432 Trichinella nativa D917_06432 I 0.000
D918_02241 Trichuris suis D918_02241 I 0.000
ECANG7_01760 Echinococcus canadensis ECANG7_01760 I 0.000
EFV53558 Trichinella spiralis EFV53558 I 0.000
TEAD3 Canis familiaris ENSCAFG00000001326 I 0.000
ENSCING00000019408 Ciona intestinalis ENSCING00000019408 I 0.000
ENSCJAG00000018829 Callithrix jacchus ENSCJAG00000018829 I 0.000
ENSCSAVG00000007634 Ciona savignyi ENSCSAVG00000007634 I 0.000
tead1a Danio rerio ENSDARG00000028159 I 0.000
tead1b Danio rerio ENSDARG00000059483 I 0.000
TEAD4 Dasypus novemcinctus ENSDNOG00000030589 I 0.000
Tead3 Dipodomys ordii ENSDORG00000010798 I 0.000
TEAD3 Equus caballus ENSECAG00000015056 I 0.000
ENSFALG00000003635 Ficedula albicollis ENSFALG00000003635 I 0.000
ENSFALG00000004805 Ficedula albicollis ENSFALG00000004805 I 0.000
TEAD3 Homo sapiens ENSG00000007866 D 0.000
TEAD4 Homo sapiens ENSG00000197905 D 0.000
tead3a Gasterosteus aculeatus ENSGACG00000009758 I 0.000
tead1b Gasterosteus aculeatus ENSGACG00000015715 I 0.000
ENSGALG00000000953 Gallus gallus ENSGALG00000000953 I 0.000
TEAD4 Gallus gallus ENSGALG00000014342 N 0.000
TEAD3 Gorilla gorilla ENSGGOG00000001847 I 0.000
ENSGMOG00000015271 Gadus morhua ENSGMOG00000015271 I 0.000
ENSLACG00000013349 Latimeria chalumnae ENSLACG00000013349 I 0.000
ENSLACG00000016444 Latimeria chalumnae ENSLACG00000016444 I 0.000
TEAD3 Loxodonta africana ENSLAFG00000014818 I 0.000
ENSLOCG00000009736 Lepisosteus oculatus ENSLOCG00000009736 I 0.000
TEAD4 Meleagris gallopavo ENSMGAG00000013910 I 0.000
TEAD3 Microcebus murinus ENSMICG00000000029 I 0.000
TEAD1 Microcebus murinus ENSMICG00000007178 I 0.000
TEAD3 Macaca mulatta ENSMMUG00000015909 I 0.000
ENSMPUG00000003624 Mustela putorius furo ENSMPUG00000003624 I 0.000
Tead4 Mus musculus ENSMUSG00000030353 D 0.000
Tead1 Mus musculus ENSMUSG00000055320 D 0.000
ENSOARG00000012126 Ovis aries ENSOARG00000012126 I 0.000
TEAD3 Otolemur garnettii ENSOGAG00000002943 I 0.000
ENSONIG00000008822 Oreochromis niloticus ENSONIG00000008822 N 0.000
TEAD4 Oryzias latipes ENSORLG00000002553 I 0.000
TEAD4 Procavia capensis ENSPCAG00000013738 I 0.000
ENSPFOG00000003170 Poecilia formosa ENSPFOG00000003170 I 0.000
ENSPFOG00000013997 Poecilia formosa ENSPFOG00000013997 I 0.000
ENSPSIG00000006176 Pelodiscus sinensis ENSPSIG00000006176 I 0.000
ENSPSIG00000017283 Pelodiscus sinensis ENSPSIG00000017283 N 0.000
TEAD3 Pan troglodytes ENSPTRG00000018086 I 0.000
TEAD3 Pteropus vampyrus ENSPVAG00000002764 I 0.000
ENSSHAG00000015930 Sarcophilus harrisii ENSSHAG00000015930 I 0.000
TEAD3 Taeniopygia guttata ENSTGUG00000001691 I 0.000
tead1a Takifugu rubripes ENSTRUG00000005940 I 0.000
tead3a Takifugu rubripes ENSTRUG00000011546 I 0.000
TEAD4 Takifugu rubripes ENSTRUG00000016489 I 0.000
TEAD3 Tursiops truncatus ENSTTRG00000009434 I 0.000
e_gw.291.69.1 Branchiostoma floridae e_gw.291.69.1 I 0.000
Gfo_R008443 Geospiza fortis Gfo_R008443 N 0.000
HelroG146479 Helobdella robusta HelroG146479 I 0.000
NEMVEDRAFT_v1g86806 Nematostella vectensis NEMVEDRAFT_v1g86806 I 0.000
nRc.2.0.1.g07693 Romanomermis culicivorax nRc.2.0.1.g07693 I 0.000
Ogr18322 Ophisaurus gracilis Ogr18322 I 0.000
PPAI001408 Phlebotomus papatasi PPAI001408 I 0.000
Pvit_05988 Pogona vitticeps Pvit_05988 I 0.000
SMAR011013 Strigamia maritima SMAR011013 I 0.000
TsM_000210300 Taenia solium TsM_000210300 I 0.000