SPU_030059 (Strongylocentrotus purpuratus)
bHLH

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00010 (HLH) IPR001092 SPU_030059 T045237_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
No direct experiments

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
twi
M03605_2.00 		Drosophila melanogaster
MACACRTGKB
VMCAYGTGTK		 SELEX
Nitta et al.(2015)
twi_1 		0.903 0.882
twi
M03606_2.00 		Drosophila melanogaster
MNDCMYRHCGVD
HBCGDYRKGHNK		 SELEX
Nitta et al.(2015)
twi_2 		0.903 0.882
twi
M05955_2.00 		Drosophila melanogaster
VCCAGATGTB
VACATCTGGB		 B1H
Zhu et al.(2011)
twi_da_SANGER_5_FBgn0003900 		0.903 0.882
twi
M05956_2.00 		Drosophila melanogaster
NAACAYRTGSNV
BNSCAYRTGTTN		 B1H
Zhu et al.(2011)
twi_FlyReg_FBgn0003900 		0.903 0.882
twi
M07538_2.00 		Drosophila melanogaster
NAACAYRTGSNV
BNSCAYRTGTTN		 DNaseI footprinting
Mathelier et al.(2014)
MA0249.1 		0.903 0.882
twi
M09657_2.00 		Drosophila melanogaster
AACAKVTGBBVD
HBVVCABMTGTT		 Misc
Kulakovskiy et al.(2009)
twi 		0.903 0.882
twi
M09892_2.00 		Drosophila melanogaster Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
I$TWI_Q6 		0.903 0.882
Twist2
M01718_2.00 		Mus musculus
NACATATGKN
NMCATATGTN		 PBM
Weirauch et al.(2014)
pTH5033 		0.859 0.902
TWIST1
M08052_2.00 		Homo sapiens
NNNCCAGATGTNN
NNACATCTGGNNN		 ChIP-seq
Mathelier et al.(2014)
MA1123.1 		0.859 0.902
TWIST1
M08722_2.00 		Homo sapiens
WAATBRRWWMCAGATGB
VCATCTGKWWYYVATTW		 Misc
Kulakovskiy et al.(2013)
TWST1_HUMAN.H11MO.0.A 		0.859 0.902
Twist1
M08766_2.00 		Mus musculus
WAATNRRWWMCAKMTGB
VCAKMTGKWWYYNATTW		 Misc
Kulakovskiy et al.(2013)
TWST1_MOUSE.H11MO.0.B 		0.859 0.902
TWIST1
M09831_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$TWIST_Q6_01 		0.859 0.902
TWIST1
M09832_2.00 		Homo sapiens Transfac license required
 Transfac license required
 Transfac
Matys et al.(2006)
V$TWIST_Q6 		0.859 0.902
For this family, TFs with SR scores > 0.838 will likely have a similar motif

DNA Binding Domains

Protein ID Domain From To Sequence
SPU_030059-tr bHLH 110 160

Links

Other bHLH family TFs
Other Strongylocentrotus purpuratus TFs

232 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
TWIST1 Homo sapiens ENSG00000122691 D 0.859
Twist2 Mus musculus ENSMUSG00000007805 D 0.859
Twist1 Mus musculus ENSMUSG00000035799 D 0.859
twi Drosophila melanogaster FBgn0003900 D 0.903
CpipJ_CPIJ012827 Culex pipiens CpipJ_CPIJ012827 I 0.862
CpipJ_CPIJ012828 Culex pipiens CpipJ_CPIJ012828 I 0.862
AAEL002902 Aedes aegypti AAEL002902 I 0.870
ACEP23430 Atta cephalotes ACEP23430 I 0.883
ACYPI001448 Acyrthosiphon pisum ACYPI001448 I 0.859
AGAP011985 Anopheles gambiae AGAP011985 I 0.870
CapteG111042 Capitella teleta CapteG111042 I 0.855
CapteG154829 Capitella teleta CapteG154829 I 0.859
CGI_10006631 Crassostrea gigas CGI_10006631 I 0.859
CGI_10013641 Crassostrea gigas CGI_10013641 I 0.883
CPIJ012827 Culex quinquefasciatus CPIJ012827 I 0.862
CPIJ012828 Culex quinquefasciatus CPIJ012828 I 0.862
DAPPUDRAFT_320202 Daphnia pulex DAPPUDRAFT_320202 I 0.859
EFV58362 Trichinella spiralis EFV58362 I 0.883
ENSACAG00000009715 Anolis carolinensis ENSACAG00000009715 I 0.870
twist1 Anolis carolinensis ENSACAG00000011825 I 0.859
ENSACAG00000015086 Anolis carolinensis ENSACAG00000015086 I 0.890
ENSAMEG00000008556 Ailuropoda melanoleuca ENSAMEG00000008556 I 0.859
ENSAMEG00000020165 Ailuropoda melanoleuca ENSAMEG00000020165 I 0.859
ENSAMXG00000024993 Astyanax mexicanus ENSAMXG00000024993 I 0.894
ENSAMXG00000025039 Astyanax mexicanus ENSAMXG00000025039 I 0.890
ENSAMXG00000025095 Astyanax mexicanus ENSAMXG00000025095 I 0.870
ENSAMXG00000025610 Astyanax mexicanus ENSAMXG00000025610 I 0.883
ENSAMXG00000025657 Astyanax mexicanus ENSAMXG00000025657 I 0.870
ENSAPLG00000000878 Anas platyrhynchos ENSAPLG00000000878 I 0.859
ENSAPLG00000007177 Anas platyrhynchos ENSAPLG00000007177 I 0.859
TWIST2 Bos taurus ENSBTAG00000021444 I 0.859
TWIST1 Bos taurus ENSBTAG00000046922 I 0.859
TWIST2 Canis familiaris ENSCAFG00000012469 I 0.859
TWIST2 Callithrix jacchus ENSCJAG00000023006 I 0.859
TWIST2 Cavia porcellus ENSCPOG00000025980 I 0.859
ENSCSAG00000018801 Chlorocebus sabaeus ENSCSAG00000018801 I 0.859
ENSCSAG00000019610 Chlorocebus sabaeus ENSCSAG00000019610 I 0.859
twist3 Danio rerio ENSDARG00000019646 I 0.890
twist1a Danio rerio ENSDARG00000030402 I 0.883
twist1b Danio rerio ENSDARG00000076010 I 0.883
twist2 Danio rerio ENSDARG00000078266 I 0.894
TWIST2 Dasypus novemcinctus ENSDNOG00000002434 I 0.859
TWIST1 Dasypus novemcinctus ENSDNOG00000037354 I 0.859
ENSDORG00000012866 Dipodomys ordii ENSDORG00000012866 I 0.859
TWIST1 Erinaceus europaeus ENSEEUG00000015333 I 0.859
TWIST2 Echinops telfairi ENSETEG00000009809 I 0.859
ENSETEG00000013115 Echinops telfairi ENSETEG00000013115 I 0.859
ENSFALG00000009781 Ficedula albicollis ENSFALG00000009781 I 0.859
ENSFALG00000014990 Ficedula albicollis ENSFALG00000014990 I 0.859
ENSFALG00000015081 Ficedula albicollis ENSFALG00000015081 I 0.903
TWIST2 Homo sapiens ENSG00000233608 I 0.859
twist2 Gasterosteus aculeatus ENSGACG00000002227 I 0.894
twist3b Gasterosteus aculeatus ENSGACG00000004773 I 0.890
TWIST1 Gasterosteus aculeatus ENSGACG00000006420 I 0.883
twist3 Gasterosteus aculeatus ENSGACG00000007963 I 0.890
twist1b Gasterosteus aculeatus ENSGACG00000008070 I 0.859
ENSGALG00000004274 Gallus gallus ENSGALG00000004274 I 0.859
ENSGALG00000006321 Gallus gallus ENSGALG00000006321 I 0.879
ENSGALG00000026059 Gallus gallus ENSGALG00000026059 I 0.859
ENSGMOG00000002790 Gadus morhua ENSGMOG00000002790 I 0.870
ENSGMOG00000003155 Gadus morhua ENSGMOG00000003155 I 0.890
ENSLACG00000012096 Latimeria chalumnae ENSLACG00000012096 I 0.859
ENSLACG00000013366 Latimeria chalumnae ENSLACG00000013366 I 0.859
ENSLACG00000019113 Latimeria chalumnae ENSLACG00000019113 I 0.879
TWIST2 Loxodonta africana ENSLAFG00000032174 I 0.859
ENSLOCG00000017835 Lepisosteus oculatus ENSLOCG00000017835 I 0.859
ENSLOCG00000018198 Lepisosteus oculatus ENSLOCG00000018198 I 0.890
ENSLOCG00000018350 Lepisosteus oculatus ENSLOCG00000018350 I 0.859
ENSMEUG00000013853 Macropus eugenii ENSMEUG00000013853 I 0.859
ENSMGAG00000002218 Meleagris gallopavo ENSMGAG00000002218 I 0.859
TWIST1 Meleagris gallopavo ENSMGAG00000009311 I 0.879
TWIST1 Myotis lucifugus ENSMLUG00000007047 I 0.859
TWIST2 Myotis lucifugus ENSMLUG00000023316 I 0.859
TWIST1 Macaca mulatta ENSMMUG00000011173 I 0.859
TWIST2 Macaca mulatta ENSMMUG00000021909 I 0.859
ENSMODG00000001412 Monodelphis domestica ENSMODG00000001412 I 0.859
TWIST1 Monodelphis domestica ENSMODG00000023924 I 0.859
ENSMPUG00000019429 Mustela putorius furo ENSMPUG00000019429 I 0.859
ENSNLEG00000011342 Nomascus leucogenys ENSNLEG00000011342 I 0.859
ENSNLEG00000019264 Nomascus leucogenys ENSNLEG00000019264 I 0.859
TWIST1 Ornithorhynchus anatinus ENSOANG00000009614 I 0.859
ENSOANG00000012950 Ornithorhynchus anatinus ENSOANG00000012950 I 0.859
ENSOARG00000000265 Ovis aries ENSOARG00000000265 I 0.859
ENSOARG00000009754 Ovis aries ENSOARG00000009754 I 0.859
TWIST2 Oryctolagus cuniculus ENSOCUG00000004073 I 0.859
TWIST2 Otolemur garnettii ENSOGAG00000029007 I 0.859
ENSONIG00000020502 Oreochromis niloticus ENSONIG00000020502 I 0.883
ENSONIG00000020610 Oreochromis niloticus ENSONIG00000020610 I 0.883
ENSONIG00000021177 Oreochromis niloticus ENSONIG00000021177 I 0.890
ENSONIG00000021342 Oreochromis niloticus ENSONIG00000021342 I 0.894
ENSONIG00000021420 Oreochromis niloticus ENSONIG00000021420 I 0.846
TWIST2 Ochotona princeps ENSOPRG00000017069 I 0.859
TWIST1 Oryzias latipes ENSORLG00000004012 I 0.859
twist1 Oryzias latipes ENSORLG00000007251 I 0.883
twist3 Oryzias latipes ENSORLG00000016373 I 0.890
twist2 Oryzias latipes ENSORLG00000018096 I 0.894
ENSPANG00000001578 Papio anubis ENSPANG00000001578 I 0.859
ENSPFOG00000019887 Poecilia formosa ENSPFOG00000019887 I 0.883
ENSPFOG00000020053 Poecilia formosa ENSPFOG00000020053 I 0.883
ENSPFOG00000020314 Poecilia formosa ENSPFOG00000020314 I 0.894
ENSPFOG00000020501 Poecilia formosa ENSPFOG00000020501 I 0.890
ENSPMAG00000003993 Petromyzon marinus ENSPMAG00000003993 I 0.859
ENSPMAG00000010126 Petromyzon marinus ENSPMAG00000010126 I 0.870
ENSPPYG00000017754 Pongo abelii ENSPPYG00000017754 I 0.859
ENSPSIG00000001961 Pelodiscus sinensis ENSPSIG00000001961 I 0.879
ENSPSIG00000012843 Pelodiscus sinensis ENSPSIG00000012843 I 0.859
ENSPTRG00000018960 Pan troglodytes ENSPTRG00000018960 I 0.859
TWIST2 Pan troglodytes ENSPTRG00000033910 I 0.859
TWIST1 Pteropus vampyrus ENSPVAG00000001710 I 0.859
Twist1 Rattus norvegicus ENSRNOG00000011101 I 0.859
Twist2 Rattus norvegicus ENSRNOG00000020355 I 0.859
ENSSHAG00000003328 Sarcophilus harrisii ENSSHAG00000003328 I 0.859
TWIST1 Sus scrofa ENSSSCG00000015370 I 0.859
TWIST2 Sus scrofa ENSSSCG00000016343 I 0.859
ENSSTOG00000004633 Ictidomys tridecemlineatus ENSSTOG00000004633 I 0.859
TWIST1 Taeniopygia guttata ENSTGUG00000002643 I 0.859
ENSTGUG00000003194 Taeniopygia guttata ENSTGUG00000003194 I 0.859
ENSTGUG00000003756 Taeniopygia guttata ENSTGUG00000003756 I 0.903
twist3 Tetraodon nigroviridis ENSTNIG00000000441 I 0.870
twist2 Tetraodon nigroviridis ENSTNIG00000001562 I 0.894
TWIST1 Tetraodon nigroviridis ENSTNIG00000001678 I 0.883
twist1b Tetraodon nigroviridis ENSTNIG00000018440 I 0.883
twist2 Takifugu rubripes ENSTRUG00000006090 I 0.894
twist3 Takifugu rubripes ENSTRUG00000011374 I 0.890
twist3 Takifugu rubripes ENSTRUG00000012607 I 0.870
twist1 Takifugu rubripes ENSTRUG00000015797 I 0.883
ENSXMAG00000019787 Xiphophorus maculatus ENSXMAG00000019787 I 0.883
ENSXMAG00000019956 Xiphophorus maculatus ENSXMAG00000019956 I 0.890
ENSXMAG00000019999 Xiphophorus maculatus ENSXMAG00000019999 I 0.870
ENSXMAG00000020062 Xiphophorus maculatus ENSXMAG00000020062 I 0.894
ENSXMAG00000020142 Xiphophorus maculatus ENSXMAG00000020142 I 0.883
twi Drosophila simulans FBgn0016355 I 0.903
twi Drosophila virilis FBgn0020065 I 0.903
twi Drosophila erecta FBgn0064598 I 0.903
twi Drosophila yakuba FBgn0084444 I 0.903
GF13559 Drosophila ananassae FBgn0090588 I 0.903
GH20971 Drosophila grimshawi FBgn0128433 I 0.903
GI21307 Drosophila mojavensis FBgn0144037 I 0.903
GL11229 Drosophila persimilis FBgn0148838 I 0.903
GM15978 Drosophila sechellia FBgn0170894 I 0.903
GK19547 Drosophila willistoni FBgn0221545 I 0.903
twi Drosophila pseudoobscura FBgn0243556 I 0.903
GB40416 Apis mellifera GB40416 I 0.883
HelroG155122 Helobdella robusta HelroG155122 I 0.877
ISCW009433 Ixodes scapularis ISCW009433 I 0.894
L798_05856 Zootermopsis nevadensis L798_05856 I 0.859
LotgiG179182 Lottia gigantea LotgiG179182 I 0.866
NEMVEDRAFT_v1g234699 Nematostella vectensis NEMVEDRAFT_v1g234699 I 0.859
NV10141 Nasonia vitripennis NV10141 I 0.859
PHUM396880 Pediculus humanus PHUM396880 I 0.870
RPRC000323 Rhodnius prolixus RPRC000323 I 0.868
SINV20920 Solenopsis invicta SINV20920 I 0.859
Smp_203270 Schistosoma mansoni Smp_203270 I 0.859
TC014598 Tribolium castaneum TC014598 I 0.859
YQE_04855 Dendroctonus ponderosae YQE_04855 I 0.859
Aan_R001044 Calypte anna Aan_R001044 I 0.859
Aan_R002857 Calypte anna Aan_R002857 I 0.859
Afo_R010658 Aptenodytes forsteri Afo_R010658 I 0.859
Afo_R013292 Aptenodytes forsteri Afo_R013292 I 0.879
Alligator_sinensis_CCG002585.1 Alligator sinensis Alligator_sinensis_CCG002585.1 I 0.859
Alligator_sinensis_CCG005115.1 Alligator sinensis Alligator_sinensis_CCG005115.1 I 0.879
Alligator_sinensis_CCG008488.1 Alligator sinensis Alligator_sinensis_CCG008488.1 I 0.859
Brh_R012765 Buceros rhinoceros Brh_R012765 I 0.859
Cflo_04586--NP_001011637.1_APIME Camponotus floridanus Cflo_04586--NP_001011637.1_APIME I 0.883
Cmyd_10002489 Chelonia mydas Cmyd_10002489 I 0.879
Cmyd_10006750 Chelonia mydas Cmyd_10006750 I 0.859
ENSP00000405176-D1 Bos grunniens ENSP00000405176-D1 I 0.859
Gfo_R012065 Geospiza fortis Gfo_R012065 I 0.859
Gfo_R014393 Geospiza fortis Gfo_R014393 I 0.903
Hsal_01530--NP_001011637.1_APIME Harpegnathos saltator Hsal_01530--NP_001011637.1_APIME I 0.859
Myotis_brandtii_Twist1_10031742 Myotis brandtii Myotis_brandtii_Twist1_10031742 I 0.859
Ogr01719 Ophisaurus gracilis Ogr01719 I 0.879
Ogr06591 Ophisaurus gracilis Ogr06591 I 0.859
Ogr11552 Ophisaurus gracilis Ogr11552 I 0.859
Ogr11553 Ophisaurus gracilis Ogr11553 I 0.859
Pvit_02271 Pogona vitticeps Pvit_02271 I 0.859
Pvit_05844 Pogona vitticeps Pvit_05844 I 0.879
estExt_gwp.C_4170045 Branchiostoma floridae estExt_gwp.C_4170045 I 0.859
fgenesh2_pm.scaffold_217000008 Branchiostoma floridae fgenesh2_pm.scaffold_217000008 I 0.859
Ocbimv22015922m.g Octopus bimaculoides Ocbimv22015922m.g I 0.859
Sakowv30001350m.g Saccoglossus kowalevskii Sakowv30001350m.g I 0.859
CLEC011700 Cimex lectularius CLEC011700 I 0.859
LCUP006189 Lucilia cuprina LCUP006189 I 0.903
LDEC006528 Leptinotarsa decemlineata LDEC006528 I 0.859
Sjc_0042560 Schistosoma japonicum Sjc_0042560 I 0.859
SMU15037660 Schmidtea mediterranea SMU15037660 I 0.859
twist1 Xenopus tropicalis XB-GENE-479802 I 0.894
twist2 Xenopus tropicalis XB-GENE-5878700 I 0.890
twist1.L Xenopus laevis XB-GENE-6255840 I 0.894
twist1.S Xenopus laevis XB-GENE-865309 I 0.894
AALB010655 Anopheles albimanus AALB010655 I 0.862
AARA000771 Anopheles arabiensis AARA000771 I 0.862
AATE005140 Anopheles atroparvus AATE005140 I 0.870
ACHR006076 Anopheles christyi ACHR006076 I 0.862
ACOM023427 Anopheles coluzzii ACOM023427 I 0.870
ACUA022223 Anopheles culicifacies ACUA022223 I 0.862
ADIR004364 Anopheles dirus ADIR004364 I 0.862
AEPI000695 Anopheles epiroticus AEPI000695 I 0.862
AFAF020800 Anopheles farauti AFAF020800 I 0.870
AFUN009694 Anopheles funestus AFUN009694 I 0.862
AMEC000330 Anopheles melas AMEC000330 I 0.870
AMEM016167 Anopheles merus AMEM016167 I 0.862
AMIN004405 Anopheles minimus AMIN004405 I 0.862
AQUA008654 Anopheles quadriannulatus AQUA008654 I 0.862
ASTEI05879 Anopheles stephensi ASTEI05879 I 0.870
BGLB003400 Biomphalaria glabrata BGLB003400 I 0.870
BGLB010605 Biomphalaria glabrata BGLB010605 I 0.858
LLOJ002131 Lutzomyia longipalpis LLOJ002131 I 0.847
MDOA005417 Musca domestica MDOA005417 I 0.903
PPAI002101 Phlebotomus papatasi PPAI002101 I 0.847
A_07561 Schistosoma haematobium A_07561 I 0.859
csin110283 Clonorchis sinensis csin110283 I 0.859
D915_00417 Fasciola hepatica D915_00417 I 0.851
D917_00468 Trichinella nativa D917_00468 I 0.883
D918_07072 Trichuris suis D918_07072 I 0.883
DILT_0001206901 Diphyllobothrium latum DILT_0001206901 I 0.859
ECANG7_02703 Echinococcus canadensis ECANG7_02703 I 0.883
ECPE_0000551801 Echinostoma caproni ECPE_0000551801 I 0.859
EmuJ_000663800 Echinococcus multilocularis EmuJ_000663800 I 0.859
HDID_0001003601 Hymenolepis diminuta HDID_0001003601 I 0.859
HmN_000912800 Hymenolepis microstoma HmN_000912800 I 0.859
HNAJ_0000179601 Hymenolepis nana HNAJ_0000179601 I 0.859
MCOS_0000111401 Mesocestoides corti MCOS_0000111401 I 0.859
PXEA_0000232401 Protopolystoma xenopodis PXEA_0000232401 I 0.851
SCUD_0002255501 Schistosoma curassoni SCUD_0002255501 I 0.851
SSLN_0000059301 Schistocephalus solidus SSLN_0000059301 I 0.859
TASK_0000180901 Taenia asiatica TASK_0000180901 I 0.859
TMUE_s0004013100 Trichuris muris TMUE_s0004013100 I 0.883
TRE_0001282801 Trichobilharzia regenti TRE_0001282801 I 0.851
TsM_000716700 Taenia solium TsM_000716700 I 0.859
TTAC_0000855201 Hydatigera taeniaeformis TTAC_0000855201 I 0.851
TTRE_0000397101 Trichuris trichiura TTRE_0000397101 I 0.883