Irx6 (Mus musculus)
Homeodomain

TF Information

Pfam ID Interpro ID Gene ID CIS-BP ID Sequence source Animal TF db
PF00046 (Homeobox) IPR001356 ENSMUSG00000031738 T212468_2.00 Ensembl (2018-Dec-8) Link out

Directly determined binding motifs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
Irx6
M00456_2.00		 Mus musculus
NNDAHWN
NWDTHNN		 PBM
Berger et al.(2008)
Irx6_2623		 (Direct) (Direct)

Motifs from related TFs

Name/Motif ID Species Forward Reverse Type/Study/Study ID SR
Score		 DBD
Identity
ara
M06518_2.00 		Drosophila melanogaster
WWACA
TGTWW		 B1H
Mathelier et al.(2014)
MA0210.1 		0.832 0.930
ara
M06313_2.00 		Drosophila melanogaster
TGTWWWNN
NNWWWACA		 B1H
Zhu et al.(2011)
Ara_Cell_FBgn0015904 		0.832 0.930
ara
M06314_2.00 		Drosophila melanogaster
DWWACA
TGTWWH		 B1H
Zhu et al.(2011)
Ara_SOLEXA_FBgn0015904 		0.832 0.930
caup
M06519_2.00 		Drosophila melanogaster
WAACA
TGTTW		 B1H
Mathelier et al.(2014)
MA0217.1 		0.824 0.895
caup
M06315_2.00 		Drosophila melanogaster
HWDWAACA
TGTTWHWD		 B1H
Zhu et al.(2011)
Caup_Cell_FBgn0015919 		0.824 0.895
caup
M06316_2.00 		Drosophila melanogaster
NDDACA
TGTHHN		 B1H
Zhu et al.(2011)
Caup_SOLEXA_FBgn0015919 		0.824 0.895
Irx4
M00416_2.00 		Mus musculus
NNNDAMAH
DTKTHNNN		 PBM
Berger et al.(2008)
Irx4_2242 		0.790 0.912
Irx2
M00386_2.00 		Mus musculus
NNDACAHNN
NNDTGTHNN		 PBM
Berger et al.(2008)
Irx2_0900 		0.780 0.860
Irx5
M00455_2.00 		Mus musculus
NNNDACAHN
NDTGTHNNN		 PBM
Berger et al.(2008)
Irx5_2385 		0.780 0.860
IRX2
M03212_2.00 		Homo sapiens
NDACAYRACAHN
NDTGTYRTGTHN		 SELEX
Jolma et al.(2013)
IRX2_1 		0.780 0.860
IRX5
M03222_2.00 		Homo sapiens
NDACAYRACAHN
NDTGTYRTGTHN		 SELEX
Jolma et al.(2013)
IRX5_1 		0.780 0.860
IRX5
M05315_2.00 		Homo sapiens
NBDTGTHNDACAYVN
NBRTGTHNDACAHVN		 SELEX
Yin et al.(2017)
IRX5_eDBD_HT-SELEX 		0.780 0.860
IRX5
M05316_2.00 		Homo sapiens
WYRYGHHNHAYRYRY
RYRYRTDNDDCRYRW		 SELEX
Yin et al.(2017)
IRX5_eDBD_Methyl-HT-SELEX 		0.780 0.860
For this family, TFs with SR scores > 0.599 will likely have a similar motif

Experimental Constructs

Motif ID Domain From To Sequence
M00456_2.00 Homeodomain 17 76

DNA Binding Domains

Protein ID Domain From To Sequence
ENSMUSP00000034185 Homeodomain 144 203
ENSMUSP00000127446 Homeodomain 144 203

Links

Other Homeodomain family TFs
Other Mus musculus TFs

390 Related TFs

Name Species Gene ID Motif Evidence SR
Score		 Action
BXY_1034900 Bursaphelenchus xylophilus BXY_1034900 I
Hba_07323 Heterorhabditis bacteriophora Hba_07323 N
AMAM014362 Anopheles maculatus AMAM014362 N
BGLB008222 Biomphalaria glabrata BGLB008222 N
ANCCAN_18840 Ancylostoma caninum ANCCAN_18840 N
ANCDUO_15583 Ancylostoma duodenale ANCDUO_15583 N
BTMF_0001429901 Brugia timori BTMF_0001429901 N
BXY_1035000 Bursaphelenchus xylophilus BXY_1035000 N
D917_04255 Trichinella nativa D917_04255 N
D918_00954 Trichuris suis D918_00954 N
AEPI009424 Anopheles epiroticus AEPI009424 N
HCOI00051800 Haemonchus contortus HCOI00051800 N
HPBE_0000946001 Heligmosomoides bakeri HPBE_0000946001 N
L893_g32898 Steinernema glaseri L893_g32898 N
NECAME_09957 Necator americanus NECAME_09957 N
nRc.2.0.1.g39124 Romanomermis culicivorax nRc.2.0.1.g39124 N
PTRK_0001274900 Parastrongyloides trichosuri PTRK_0001274900 N
SVUK_0000102101 Strongylus vulgaris SVUK_0000102101 N
TTRE_0000574401 Trichuris trichiura TTRE_0000574401 N
ISCW018372 Ixodes scapularis ISCW018372 N
CapteG78125 Capitella teleta CapteG78125 N
EFV52039 Trichinella spiralis EFV52039 N
GF17143 Drosophila ananassae FBgn0094162 N
GF17175 Drosophila ananassae FBgn0094193 N
GH12158 Drosophila grimshawi FBgn0119637 N
GI10902 Drosophila mojavensis FBgn0133665 N
GJ18548 Drosophila virilis FBgn0205706 N
HMEL014400 Heliconius melpomene HMEL014400 N
AAEL013374 Aedes aegypti AAEL013374 N
KGM_20032 Danaus plexippus KGM_20032 N
MCINX008008 Melitaea cinxia MCINX008008 N
RPRC004296 Rhodnius prolixus RPRC004296 N
TC001693 Tribolium castaneum TC001693 N
CLEC006296 Cimex lectularius CLEC006296 N
HHAL001513-PA Halyomorpha halys HHAL001513-PA N
LCUP009247 Lucilia cuprina LCUP009247 N
Minc05254 Meloidogyne incognita Minc05254 N